LOCUS       NM_199032               5539 bp    mRNA    linear   ROD 09-JUL-2024
DEFINITION  Mus musculus centrosomal protein 135 (Cep135), mRNA.
ACCESSION   NM_199032 XM_006535023 XM_355607
VERSION     NM_199032.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5539)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5539)
  AUTHORS   Wang,K., Wang,X., Zhao,F., Zhao,Q., Kong,S., Ma,P., Wu,G., Wang,W.
            and Zhang,X.
  TITLE     Centrosomal Protein CEP135 Regulates the Migration and Angiogenesis
            of Endothelial Cells in a Microtubule-Dependent Manner
  JOURNAL   Front Biosci (Landmark Ed) 28 (11), 303 (2023)
   PUBMED   38062802
  REMARK    GeneRIF: Centrosomal Protein CEP135 Regulates the Migration and
            Angiogenesis of Endothelial Cells in a Microtubule-Dependent
            Manner.
REFERENCE   3  (bases 1 to 5539)
  AUTHORS   Gonzalez-Martinez,J., Cwetsch,A.W., Martinez-Alonso,D.,
            Lopez-Sainz,L.R., Almagro,J., Melati,A., Gomez,J.,
            Perez-Martinez,M., Megias,D., Boskovic,J., Gilabert-Juan,J.,
            Grana-Castro,O., Pierani,A., Behrens,A., Ortega,S. and Malumbres,M.
  TITLE     Deficient adaptation to centrosome duplication defects in neural
            progenitors causes microcephaly and subcortical heterotopias
  JOURNAL   JCI Insight 6 (16), e146364 (2021)
   PUBMED   34237032
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5539)
  AUTHORS   Otto,T., Candido,S.V., Pilarz,M.S., Sicinska,E., Bronson,R.T.,
            Bowden,M., Lachowicz,I.A., Mulry,K., Fassl,A., Han,R.C.,
            Jecrois,E.S. and Sicinski,P.
  TITLE     Cell cycle-targeting microRNAs promote differentiation by enforcing
            cell-cycle exit
  JOURNAL   Proc Natl Acad Sci U S A 114 (40), 10660-10665 (2017)
   PUBMED   28923932
REFERENCE   5  (bases 1 to 5539)
  AUTHORS   Mizuno,S., Takami,K., Daitoku,Y., Tanimoto,Y., Dinh,T.T.,
            Mizuno-Iijima,S., Hasegawa,Y., Takahashi,S., Sugiyama,F. and
            Yagami,K.
  TITLE     Peri-implantation lethality in mice carrying megabase-scale
            deletion on 5qc3.3 is caused by Exoc1 null mutation
  JOURNAL   Sci Rep 5, 13632 (2015)
   PUBMED   26346620
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5539)
  AUTHORS   Kinzel,D., Boldt,K., Davis,E.E., Burtscher,I., Trumbach,D.,
            Diplas,B., Attie-Bitach,T., Wurst,W., Katsanis,N., Ueffing,M. and
            Lickert,H.
  TITLE     Pitchfork regulates primary cilia disassembly and left-right
            asymmetry
  JOURNAL   Dev Cell 19 (1), 66-77 (2010)
   PUBMED   20643351
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC127332.3.
            
            On Dec 27, 2021 this sequence version replaced NM_199032.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223969.5689.1,
                                           SRR9219380.41611.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               AC127332.3         133478-133703
            227-383             AC127332.3         136494-136650
            384-574             AC127332.3         137971-138161
            575-742             AC127332.3         138802-138969
            743-884             AC127332.3         140172-140313
            885-969             AC127332.3         142136-142220
            970-1098            AC127332.3         146166-146294
            1099-1314           AC127332.3         147916-148131
            1315-1380           AC127332.3         151501-151566
            1381-1519           AC127332.3         154410-154548
            1520-1743           AC127332.3         156429-156652
            1744-1896           AC127332.3         160417-160569
            1897-2049           AC127332.3         161582-161734
            2050-2127           AC127332.3         166063-166140
            2128-2279           AC127332.3         169406-169557
            2280-2395           AC127332.3         175444-175559
            2396-2550           AC127332.3         175632-175786
            2551-2606           AC127332.3         176204-176259
            2607-2775           AC127332.3         176938-177106
            2776-2886           AC127332.3         178452-178562
            2887-3072           AC127332.3         178931-179116
            3073-3282           AC127332.3         181641-181850
            3283-3485           AC127332.3         182843-183045
            3486-3590           AC127332.3         183701-183805
            3591-3704           AC127332.3         185661-185774
            3705-5539           AC127332.3         189411-191245
FEATURES             Location/Qualifiers
     source          1..5539
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 41.31 cM"
     gene            1..5539
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="centrosomal protein 135"
                     /db_xref="GeneID:381644"
                     /db_xref="MGI:MGI:2681869"
     exon            1..226
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            227..383
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     CDS             271..3693
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="centrosomal protein 4"
                     /codon_start=1
                     /product="centrosomal protein of 135 kDa"
                     /protein_id="NP_950197.1"
                     /db_xref="CCDS:CCDS19365.1"
                     /db_xref="GeneID:381644"
                     /db_xref="MGI:MGI:2681869"
                     /translation="MTTAAERKYINIRKRLDQLGYRQTLSVDSLPLVEKLFSDLVHTT
                     ESLRQCRLSSGKAEKESANLDFVLEPYKLENTRLNKENNELYLELMKLRECSDKHIKD
                     LKTTLKKCSRETADLKFLNNQYVHKVKVLEKESKAKDEKIQQLQEKNLRAVVQTPGGR
                     KRNIAFRRQRMQIDEPAPPSEVSAYPVPQPEDPYIADLLQVADNRIQELQEEVQQLQE
                     KLAQMEKGVLDYSKQIELREREIQRLSLALDGGCSPDVLSLETRNKTNEKLIAHLNVQ
                     VDFLQQANKELEKHIQELMETKETVTTEVVNLSNRNEKLCQELTEIDQLAQRLERHKE
                     QVLETADKELGEAKKEIKRNLCEMRNLEEKMSKLQWELDLSHKEKERLNSELLLKSDL
                     ETVVHQLEQEKQRLSKKLQSFAVTERELTLEVERMRLEHGIKRRDKSPSRLDTFLKGI
                     EEERDYYKKELEKLQHLIQRRSCAINYSAREKPPVVKCSEKGDCSTDVHLITRERDEL
                     QRMLERFEKYMEDIQSNVKLLTAERDKLNVLYKEAKEELSTLRKESTNSTSPNHLVSC
                     VEKEKERALSELRRITAEKEALREKLKNIQERNAVGKSDLEKTIEHLTYINHQLENEK
                     YELQSKMLMMKETVESLENKSKLQAQKLSHVTGDSSHQKTEMTSLRIVSEQLQRSLDD
                     CQHRLSIKRGELESAQEQIKMLEQKLENLSHRMTVQSEETHAMKKTIGVMDKEKDFLQ
                     ETVDEKTEKIANLQESLLSKEKVIAQLKVTVAEYETSLNQLQETLTTRDREINSLRRQ
                     LDASHKELDDVGKSREISFKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVH
                     KYITEVSRWESLMAAKEKENKDLLDRFQMLHSRAEDWEVKAQQAEGENSSVRLELLSI
                     DTERRHLRERVDLLEKEIQEHINAHHAYESQISSMAKAMSQLEEELRRHESEKATMLG
                     DVSSLRELCIKLDSGKDVMTQQLNSKSLELERAVAELENVKSESELLKKQLTNERQTI
                     KNLESLLATNRDKEFQSHLTSHEKDTEIQLLKEKLNLSESKLTTQSRETSMLRTKVTQ
                     LQTDYDNLKRQMSNEKYERERAIQEMRRLGLPTSPLSSTLKSPVQTPDHINA"
     exon            384..574
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            575..742
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            743..884
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            885..969
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1098
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1314
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1380
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1519
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1743
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            1744..1896
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            1897..2049
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2127
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2128..2279
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2280..2395
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2396..2550
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2551..2606
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2775
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2776..2886
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            2887..3072
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            3073..3282
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            3283..3485
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            3486..3590
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            3591..3704
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     exon            3705..5539
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3958..3963
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="hexamer: ACTAAA"
     polyA_site      3977
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="major polyA site"
     regulatory      4048..4053
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="hexamer: AATATA"
     polyA_site      4076
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
     regulatory      5514..5519
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="hexamer: AATAAA"
     polyA_site      5539
                     /gene="Cep135"
                     /gene_synonym="Cep4; Gm1044"
                     /note="major polyA site"
ORIGIN      
        1 ccgagggccg aaagccgcca tctccgggcg gccggcgcgc gcgccgccac tgtgggccgc
       61 tccggtccgt taccggggca acggcggcgc tccctccttg tgggccgcga ccgtctctct
      121 ccgcgccatt ttcaaaccgc gctcgtgccg gagccattgg ccgcagcagg acgagccagc
      181 ggggacagcg ggtccggagg gcgatgtacc tcgggacgga gcggcggcct ttaagttggg
      241 agtgtgacta aaactggttt tggaagcaag atgactacag ctgcagagag aaagtatatt
      301 aacattcgga agaggttaga ccagctgggc taccgccaga ccctgtcagt ggacagtctg
      361 cctttggtag aaaaactttt cagtgacctc gttcatacga cagaaagcct gcggcagtgc
      421 aggttgtcct cgggaaaggc ggaaaaggaa agtgccaatc tcgattttgt tttggaacct
      481 tataaacttg aaaatacaag actgaataag gagaataatg aattgtatct ggagttaatg
      541 aagctcagag aatgctcaga caagcacatt aaagacttga agacgacact gaagaaatgt
      601 tcccgtgaga cagctgatct gaagtttctg aacaaccagt atgttcacaa ggtcaaagtc
      661 ctggagaaag agagcaaagc caaggatgaa aagatccagc agcttcaaga gaagaacctg
      721 cgtgctgtgg tgcagacccc tggtggcagg aaaagaaaca ttgcatttag gcgccagcgg
      781 atgcaaatcg atgaaccagc cccaccctca gaagtcagcg catacccggt tcctcaacca
      841 gaagacccat acattgcgga cctcctgcaa gtggctgaca acaggattca ggagctgcag
      901 gaggaggtcc agcagctgca ggagaagcta gcacagatgg agaaaggagt gctggactac
      961 agcaagcaga ttgaactgag agaacgagaa atacagcgac tgtcacttgc gttggatggc
     1021 ggttgttccc ctgatgtcct gtctctggag accagaaata aaaccaatga gaaactcatt
     1081 gctcacttaa atgtccaggt tgacttcctc cagcaagcta ataaagagct ggagaagcat
     1141 attcaagagc tcatggaaac caaggaaaca gtgacaactg aagttgtgaa cctcagcaac
     1201 agaaacgaga agctctgcca ggagctaacc gagatcgacc agttagccca gcggctggaa
     1261 aggcacaagg agcaagtgct ggagacagca gacaaggagc tcggggaggc aaagaaagag
     1321 attaaacgaa acctctgtga aatgcggaac cttgaggaaa aaatgtcaaa actgcagtgg
     1381 gaattggact taagccataa ggagaaggag agactgaaca gtgagctgct tttaaagtca
     1441 gacctggaga ctgttgttca tcagctcgaa caagaaaagc aaagacttag caaaaagctg
     1501 cagagttttg cagtcacaga aagagaactg actctggagg ttgagaggat gaggctagaa
     1561 catgggataa agcgtcggga caagtcaccc tctcgtctgg acacatttct gaaaggcata
     1621 gaggaagagc gcgattatta caagaaagag ctggagaaac tgcagcatct aatccagcgg
     1681 agatcttgtg cgattaatta ctccgctcgg gaaaaacctc ctgtagtcaa atgctcagaa
     1741 aagggtgact gcagcacgga cgttcacctg atcacaagag aaagggatga acttcagcgc
     1801 atgctggaga gattcgagaa atacatggag gacatacagt ccaacgtgaa gctgctgacg
     1861 gcggaaaggg acaagctgaa tgtcctgtat aaggaagcaa aggaagagtt gtctacacta
     1921 aggaaggagt ccactaattc gacatccccc aaccatcttg ttagttgtgt agaaaaggag
     1981 aaagaacgcg cgttatctga gttgagaaga attacagcag aaaaggaagc tctgagagaa
     2041 aagttgaaaa acatccaaga aaggaatgct gttggaaaat cagacttaga gaaaactatt
     2101 gaacatttga catatattaa tcaccagctt gaaaatgaaa aatatgaatt gcaatctaaa
     2161 atgttaatga tgaaagaaac agtggagtca ttagagaaca aatcaaaact ccaagctcaa
     2221 aagcttagcc atgtgactgg tgactcatct catcagaaaa cagagatgac ctcccttagg
     2281 atcgtcagtg agcagctaca gcgctcactt gatgactgtc agcaccgact ttccataaaa
     2341 agaggtgaac ttgaatcagc ccaagagcaa attaaaatgc tggagcaaaa actagagaat
     2401 ctcagccaca ggatgacggt gcagagcgaa gagactcacg ccatgaagaa gaccattgga
     2461 gtgatggaca aagaaaagga ctttctccag gagactgtgg atgagaagac agaaaagatc
     2521 gccaacctgc aggaaagcct ccttagtaaa gaaaaagtca ttgcccagtt gaaggtcaca
     2581 gttgcagagt atgaaacatc acttaaccag ctacaagaaa ctttgactac tcgagaccga
     2641 gagataaaca gcctccggcg ccagcttgat gcatctcaca aggagcttga tgatgttggg
     2701 aaatctagag agatctcttt taaggaaaat agaaggttac aagatgacct ggccacaatg
     2761 gcgagagaaa atcaggagat ctcactggag ctggaagcag cagtgcaaga aaaagaagag
     2821 atgaagagca gagtccataa gtacatcact gaggtgtcgc ggtgggagag cctgatggcc
     2881 gccaaggaaa aagaaaacaa agacttgctg gatagattcc agatgctcca cagccgtgct
     2941 gaggactggg aggtcaaggc tcagcaagcg gaaggggaga acagctcagt ccgcctggag
     3001 ctgctgtcta tcgacacaga gagaaggcat ctgcgggaac gagtggacct cctggagaag
     3061 gagatccagg agcacatcaa tgcacatcac gcatacgagt ctcagatctc gtcaatggct
     3121 aaggccatgt ctcagttaga agaggagctg cgacgtcatg agagcgagaa agccaccatg
     3181 ttaggtgacg tgtcgtctct ccgagaactg tgcatcaagc tcgactcagg caaagacgtc
     3241 atgacccagc agctgaattc caaaagccta gagctggagc gggcggtagc agaattagag
     3301 aatgtaaaat cagaatcaga actattaaaa aaacagctga cgaatgagag acagacaatt
     3361 aaaaaccttg agtcgttgtt agctacaaac agagataaag agttccagtc ccatttaacc
     3421 tcccacgaga aggacacaga aatccagctg ctgaaggaga agctaaatct ctcagaaagc
     3481 aaactgacta cccaaagccg agaaacctcc atgcttcgaa ctaaagtgac acagttgcag
     3541 acagattatg ataatctgaa gaggcagatg tcaaacgaga agtacgaacg agagcgagca
     3601 atccaagaga tgcgccgact tggtcttcct acatcacctc tgagctctac tctgaaatct
     3661 cctgtacaga ctcctgatca tataaatgca tagttaccag gaagattatg gttttcagtg
     3721 agtttctgcg tggatttttt aagaacacag agtaatgaga tatttgaagt tcttgttcct
     3781 gcaaatcatg aacactgaca caaattctac ctctgtcaac ctttatttaa atcagtggat
     3841 atttatgtaa aaatgtttag ttttaaaaga gccttatatg tatattttca tatgtgaaaa
     3901 aacaaaatat gtattaatag cttaactgat gtgatatgtg aatttttatt attcccaact
     3961 aaaattactc cttacaatgt gtttatactg tgaattgctt taacatgctc acattatgct
     4021 ttaataatct gtgccttagt gaaccataat atatgcatgg aaggattctt gcactattta
     4081 ggtttcgtgc ctgtgtttat agcccatagc atgatgaatt cagaaaatga tccatttgat
     4141 gctgttccgt aagtgtgaca tcagtccacg tgtgctgtct atcacacagg ggagtctatc
     4201 taaatctagt ctaatagaac tctttttatt ttaaaagtaa agaaagagtt tatgtgagct
     4261 tctgtttcca gagagttagg actccctcag ggaagccgag cggctgacag cgagctcacc
     4321 acacagagcc tagagtggcc aggaagtagg ggaagctgtg tactccgaaa gccctccccc
     4381 cagggacgca cttgctccag taaatctgca cctcttagac ctcctcaaac agcaccccca
     4441 cacacctggg gccaagtgtt caagtctctg ggtctgtctg tgggatacat ttctcattca
     4501 gactacattt tctaaaacca aaaattcaac tgataccaat tttcccccct gaggtgtttt
     4561 ttgctatttc tgaaagttca gacctactgg aggtcaataa actcagctat ctgtttgcaa
     4621 attacttaca ttttcatcaa ctttgaaaaa cattttcctg gctatagagg aaataaatgt
     4681 gcctagtgat ctcatctgga taaaatagtt atcgccgtgt gtgatagtgc aagcaggaag
     4741 ggcggcagtg ggagacactt ttatctatgt gggccttatt tgggctgtcc tatgcgctct
     4801 ccacatgaca catttttttt aagaattaag ttaaaataat tcagagtttt gtaaaataat
     4861 caaatgaaaa ttttttttac taactaaatt cttcagtgta ctagtctaaa atttcagaat
     4921 atgaaagtat ataaagtaaa tatagaaaag tgttttgtta aaagtccaat atgcatctga
     4981 taatacctat ttgtggctcc aaatcctatc taatatcccc agtctttccg aatagtatgt
     5041 caacaccatc cctgtgccgt ataaattgaa aacacctttt tataacttcc ctttcaaggt
     5101 tgtgtaactc tgaagaattg aggtgtatgc tcagccttag aaaagagtag acatacaaaa
     5161 taaaatgtcg acaccaatac taatcatgta ccaactgttc gcgtttgaag aaacccctct
     5221 tttataacta gatttcatta tggttgagaa agaacttaaa agtcagcgca ggccagcgag
     5281 tcagctggga gcaacccgct ttgtttcctc ttggcttaaa gcaagttgct ctctgtgaac
     5341 gtccctgagg gtgggtagac atccaggtaa ctagtgtgcc ttatgtggtc aggatgttcc
     5401 ctttgcaata atttgctgca tagttgagta cagggcgact tactctccca ctatgtgtat
     5461 aatttattca ttctatctcc tttgagtaaa ttcatgtttt atagcaaaat atgaataaaa
     5521 aggaccattt acaatgtca
//
