LOCUS       NM_001109747            1527 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus centromere protein W (Cenpw), mRNA.
ACCESSION   NM_001109747 XM_488549 XM_906204
VERSION     NM_001109747.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1527)
  AUTHORS   Tian,T., Chen,L., Dou,Z., Yang,Z., Gao,X., Yuan,X., Wang,C.,
            Liu,R., Shen,Z., Gui,P., Teng,M., Meng,X., Hill,D.L., Li,L.,
            Zhang,X., Liu,X., Sun,L., Zang,J. and Yao,X.
  TITLE     Structural insights into human CCAN complex assembled onto DNA
  JOURNAL   Cell Discov 8 (1), 90 (2022)
   PUBMED   36085283
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1527)
  AUTHORS   Simonson,L., Vold,S., Mowers,C., Massey,R.J., Ong,I.M.,
            Longley,B.J. and Chang,H.
  TITLE     Keratin 13 deficiency causes white sponge nevus in mice
  JOURNAL   Dev Biol 468 (1-2), 146-153 (2020)
   PUBMED   32758484
REFERENCE   3  (bases 1 to 1527)
  AUTHORS   Wang,Y., Fan,L.H., Yue,W., Ouyang,Y.C., Wang,Z.B., Hou,Y.,
            Schatten,H. and Sun,Q.Y.
  TITLE     CENP-W regulates kinetochore-microtubule attachment and meiotic
            progression of mouse oocytes
  JOURNAL   Biochem Biophys Res Commun 527 (1), 8-14 (2020)
   PUBMED   32446395
  REMARK    GeneRIF: CENP-W regulates kinetochore-microtubule attachment and
            meiotic progression of mouse oocytes.
REFERENCE   4  (bases 1 to 1527)
  AUTHORS   Geister,K.A., Brinkmeier,M.L., Cheung,L.Y., Wendt,J., Oatley,M.J.,
            Burgess,D.L., Kozloff,K.M., Cavalcoli,J.D., Oatley,J.M. and
            Camper,S.A.
  TITLE     LINE-1 Mediated Insertion into Poc1a (Protein of Centriole 1 A)
            Causes Growth Insufficiency and Male Infertility in Mice
  JOURNAL   PLoS Genet 11 (10), e1005569 (2015)
   PUBMED   26496357
  REMARK    GeneRIF: We determined that Poc1a, encoding protein of the
            centriole 1a, is disrupted by the insertion of a processed Cenpw
            cDNA, which is flanked by target site duplications, suggestive of a
            LINE-1 retrotransposon-mediated event
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1527)
  AUTHORS   Lee,S., Gang,J., Jeon,S.B., Choo,S.H., Lee,B., Kim,Y.G., Lee,Y.S.,
            Jung,J., Song,S.Y. and Koh,S.S.
  TITLE     Molecular cloning and functional analysis of a novel oncogene,
            cancer-upregulated gene 2 (CUG2)
  JOURNAL   Biochem Biophys Res Commun 360 (3), 633-639 (2007)
   PUBMED   17610844
REFERENCE   6  (bases 1 to 1527)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   7  (bases 1 to 1527)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG804382.1, AK141272.1 and BF453953.1.
            
            On or before Oct 6, 2007 this sequence version replaced
            XM_906204.2, XM_488549.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG804382.1, AK141272.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                BG804382.1         1-19
            20-1497             AK141272.1         2-1479
            1498-1527           BF453953.1         1-30                c
FEATURES             Location/Qualifiers
     source          1..1527
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 16.93 cM"
     gene            1..1527
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /note="centromere protein W"
                     /db_xref="GeneID:66311"
                     /db_xref="MGI:MGI:1913561"
     exon            1..180
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..321
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /note="cancer-up-regulated gene 2 protein; CENP-W"
                     /codon_start=1
                     /product="centromere protein W"
                     /protein_id="NP_001103217.1"
                     /db_xref="CCDS:CCDS35876.1"
                     /db_xref="GeneID:66311"
                     /db_xref="MGI:MGI:1913561"
                     /translation="MAPSTTVTRRVKRKAPRAFLKRTLKQKKPHLGLGRCCDLLIHLN
                     CLLFIQRLAEESRTNACESKSRVIKKDHVLAAGKVILKKSRG"
     exon            181..294
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /inference="alignment:Splign:2.1.0"
     exon            295..1512
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      397..402
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /note="hexamer: ATTAAA"
     polyA_site      423
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /note="major polyA site"
     regulatory      1350..1355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /note="hexamer: AATAAA"
     polyA_site      1389
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
     regulatory      1488..1493
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
                     /note="hexamer: AATAAA"
     polyA_site      1512
                     /gene="Cenpw"
                     /gene_synonym="2610036L11Rik; Cug2"
ORIGIN      
        1 gggaggcaag tggcgtgtca gtctgtggtg agcggccctg acgtgcgacg ggccgcgagg
       61 atggcgccct ccaccacagt cactaggcgg gtaaagcgca aggcgccccg cgccttcctc
      121 aagcgcacct taaagcagaa gaagcctcac ctaggtctgg ggaggtgctg cgacctcctg
      181 atccatttga attgcctact ttttattcag cgattggcag aagagtccag gacaaatgct
      241 tgtgaaagta aatctagagt tatcaaaaag gatcatgtac tggctgcagg aaaggtaatt
      301 ctgaagaaga gcagaggtta ggtgtcagca tgtgcttaag cattatatga tatgttaatt
      361 taaaacactt ttatgtatca gtttatattg tggtttatta aaacattgag gaattatgct
      421 ttattcatta atggcttctg agtttctttt gtgttactgt gttgttcctt agtgtgtcaa
      481 aaatgaaatc atgctgtatt gaatagcttg aagagatgtg tactcctttg actaaagctt
      541 atgtctttga atttagccag aattatgctg tgaatttaac ttctaagaaa gcaacataca
      601 gtaaaatctg ggtacatttt aaagatgtta attttggatg aattcacaaa acactatttt
      661 tttgttacac tagtagtaat agtaaaattt ctcaattaga agattgtaag catcagctaa
      721 agtttttaca aacttgtttc catctataaa ccacaaacaa gaagatgtaa atcaaactga
      781 tatactttct tcagtcatga gatttagtag ataaggcatt ttcccatgtc aatcttttgg
      841 aagcttacta tataatattt agttttcact tttgttctga gataattcag atagtatatg
      901 aaattacaaa gctaatataa acatacattc tacattaaac acccagtttc ctcaatgctt
      961 atatagaata tatagtgtaa tatatcaaaa gcaagacttt ggtaattgaa acagtatatg
     1021 tgtagctcca tgctatttta tcatgtgtac tgattatgca attatagaac tacctcagta
     1081 ccacagaggt cttgttgatt tatactcatc cagctaccat gtcctctgct agtctactac
     1141 cctaaccaac ttttctccag ctctatagtt ttgagaatgg aagcatgtca gaaataagca
     1201 ttggagatgt ttttcactca gtgtaatact cttgtgatct gtcccagtca ttgcatctct
     1261 tcactgctga gtgtggatac accatatttt gtatagttgg tttgcctatt gaagagcatt
     1321 ttgatttgtc aaatttgggg attgctataa ataaaatttc tatgaatgat tgtaaacagt
     1381 tttttaaaat ctgtgtaagt tttcactttt ttttctagga aaaatgccta gaagtttgct
     1441 tgataggtca aatggcaaat ctatgtttaa ctttaaaaaa ataaagaaat aaaaactaca
     1501 tagctaaagc aaaaaaaaaa aaaaaaa
//
