LOCUS       NM_177150               1767 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus centromere protein T (Cenpt), mRNA.
ACCESSION   NM_177150 XM_001476693
VERSION     NM_177150.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1767)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1767)
  AUTHORS   Werren,E.A., LaForce,G.R., Srivastava,A., Perillo,D.R., Li,S.,
            Johnson,K., Baris,S., Berger,B., Regan,S.L., Pfennig,C.D., de
            Munnik,S., Pfundt,R., Hebbar,M., Jimenez-Heredia,R.,
            Karakoc-Aydiner,E., Ozen,A., Dmytrus,J., Krolo,A., Corning,K.,
            Prijoles,E.J., Louie,R.J., Lebel,R.R., Le,T.L., Amiel,J.,
            Gordon,C.T., Boztug,K., Girisha,K.M., Shukla,A., Bielas,S.L. and
            Schaffer,A.E.
  TITLE     TREX tetramer disruption alters RNA processing necessary for
            corticogenesis in THOC6 Intellectual Disability Syndrome
  JOURNAL   Nat Commun 15 (1), 1640 (2024)
   PUBMED   38388531
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1767)
  AUTHORS   Tian,T., Chen,L., Dou,Z., Yang,Z., Gao,X., Yuan,X., Wang,C.,
            Liu,R., Shen,Z., Gui,P., Teng,M., Meng,X., Hill,D.L., Li,L.,
            Zhang,X., Liu,X., Sun,L., Zang,J. and Yao,X.
  TITLE     Structural insights into human CCAN complex assembled onto DNA
  JOURNAL   Cell Discov 8 (1), 90 (2022)
   PUBMED   36085283
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1767)
  AUTHORS   Wang,Y., Li,J., Dong,F., Yue,W., Ouyang,Y.C., Wang,Z.B., Hou,Y.,
            Schatten,H. and Sun,Q.Y.
  TITLE     CENP-T regulates both the G2/M transition and anaphase entry by
            acting through CDH1 in meiotic oocytes
  JOURNAL   J Cell Sci 133 (3) (2020)
   PUBMED   31964702
  REMARK    GeneRIF: CENP-T regulates both the G2/M transition and anaphase
            entry by acting through CDH1 in meiotic oocytes.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1767)
  AUTHORS   Nakano,Y., Jahan,I., Bonde,G., Sun,X., Hildebrand,M.S.,
            Engelhardt,J.F., Smith,R.J., Cornell,R.A., Fritzsch,B. and Banfi,B.
  TITLE     A mutation in the Srrm4 gene causes alternative splicing defects
            and deafness in the Bronx waltzer mouse
  JOURNAL   PLoS Genet 8 (10), e1002966 (2012)
   PUBMED   23055939
REFERENCE   6  (bases 1 to 1767)
  AUTHORS   Keegan,C.E., Hutz,J.E., Else,T., Adamska,M., Shah,S.P., Kent,A.E.,
            Howes,J.M., Beamer,W.G. and Hammer,G.D.
  TITLE     Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd)
            mice is caused by a splicing mutation in a novel telomeric
            regulator
  JOURNAL   Hum Mol Genet 14 (1), 113-123 (2005)
   PUBMED   15537664
REFERENCE   7  (bases 1 to 1767)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK090340.1.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_001476693.1, NM_177150.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090340.1, AK167376.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1767              AK090340.1         2-1768
FEATURES             Location/Qualifiers
     source          1..1767
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 53.05 cM"
     gene            1..1767
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /note="centromere protein T"
                     /db_xref="GeneID:320394"
                     /db_xref="MGI:MGI:2443939"
     exon            1..138
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1573
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /note="CENP-T"
                     /codon_start=1
                     /product="centromere protein T"
                     /protein_id="NP_796124.1"
                     /db_xref="CCDS:CCDS22615.1"
                     /db_xref="GeneID:320394"
                     /db_xref="MGI:MGI:2443939"
                     /translation="MADLSFSDGDPTVRTLLRRVLETADSRTPMRRRSTRINAQRRRS
                     QTPYSNRQGSQTKTSARKQSHGARSVGRSTRVQGRGRLEEQTPRTLLRNILLTAPESS
                     TVMPDPVVKPAQVPEVARSSRRESSRGSLELHLPELEPPSTLAPGLTAPGKRKQKLRL
                     SVFQQEVDQGLPLSQEPRRSRSADVSSLASSFNLTFVLPGQPETVERPGLARRRPIRQ
                     LVNAGALLQDLEDNSLASALPGDSHRTPVAALPMDVGLEDTQPFSQSLAAFSLSGKHS
                     LPSPSRPGVEDVERVMGPPSSGTRLQSRMSRSGPAASPSPFLEPQPPPAEPREAVGSN
                     EAAEPKDQEGSSGYEETSARPASGELSSSTHDSLPAEQPPPSPGVAVLSSEPLESVTA
                     KCPSRTQTAGPRRRQDPHKAGLSPYVKFFSFCTKMPVEKTALEIVEKCLDKYFQHLCN
                     DLEVFASHAGRKIVKPEDLLLLMRRQGLVTDQVSQHVLVERYLPLEYRQQLIPCAFSG
                     NSVFPAQ"
     exon            139..229
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            230..317
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            318..414
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            415..551
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            552..594
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            595..743
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            744..938
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1091
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1167
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1344
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1449
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1767
                     /gene="Cenpt"
                     /gene_synonym="G630055P03Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttaggagg ggtggggtcc tgaacatggc ggacctcagc ttttctgacg gcgatcctac
       61 tgtacgcacg cttttgcggc gcgtgctgga gacggcggat tcgcgcactc cgatgagacg
      121 ccggagcact cggatcaatg cacaaagaag acggtctcaa acgccatact ctaacaggca
      181 gggtagccaa acaaagacaa gtgctaggaa gcaatcccat ggagctaggt cagttggcag
      241 atcgactcgt gttcaaggtc gtgggcgcct ggaggaacag acaccccgga ctctgctaag
      301 gaatatctta ctaactgccc cagaatcgtc cactgtgatg ccagacccag tggtgaagcc
      361 agcacaagta ccagaagtgg cccggtcctc cagacgggag agcagtcggg gaagcctgga
      421 gctacacctt cctgaactgg agcccccctc aaccctggct ccgggtctaa cagcccctgg
      481 caaaaggaag cagaaactga gattatcagt atttcagcag gaagtggacc aggggttgcc
      541 tctctcccaa gagccacgta ggagtaggag tgctgatgtt tcatccttgg ctagctcctt
      601 caatcttacc tttgttctac ctggtcagcc agagacagtg gagagacctg gtctggctcg
      661 aagacgtccc atccgccagc ttgtgaatgc tggtgctctt ttgcaggatc tggaagacaa
      721 ttccttagcc tctgctcttc caggtgacag tcacagaaca cctgttgctg ctctgccgat
      781 ggatgtaggc ttggaagaca cacagccttt ctcacagtcc ttggctgcct tttcccttag
      841 tgggaaacat tctctgccca gcccttctcg ccctggggtt gaagatgttg aaagagttat
      901 gggcccacca agctcgggga ccaggctgca aagccggatg agcagatctg gccctgctgc
      961 ctctccttcc cccttcctgg agccacagcc tccgcctgca gaaccgagag aagcagtagg
     1021 atccaacgag gctgcggagc ccaaggatca agaaggatct tcagggtatg aggaaacttc
     1081 tgctaggcca gcaagtggag aattatcctc cagcacacat gactcactcc cagctgaaca
     1141 gccacccccg tcacctggag ttgcagtcct atcttcagag cccctggagt ctgtgacagc
     1201 taagtgccca tccaggaccc aaactgcagg tcctaggcgc cgccaagacc cccacaaggc
     1261 tggactgagc ccctatgtga agttcttcag cttctgtact aagatgcccg tggagaagac
     1321 ggctcttgag atagtagaga agtgcctaga caagtatttc cagcaccttt gcaatgacct
     1381 ggaggtattt gcttctcatg ctggccgtaa gattgtgaag ccagaggact tattgctgct
     1441 gatgcgacgg cagggactag tgactgatca agtctcgcag catgtgctcg tggagcggta
     1501 cctgcccttg gagtaccggc aacaacttat cccttgtgca ttcagtggca attctgtctt
     1561 ccctgcacag taggaccagg ccttccctgg cacctactct ccctaccttg gaaatcttga
     1621 accctacaca atcatgaagg ttccctcatc tcctggcacc aagaaagtct cacaaatggg
     1681 ttcttctgct ttgtggtgca tgtcttagga cctgcccagg ttgccttccc ccagcctgga
     1741 aaggaatagg aattaaagac tttatac
//
