LOCUS       NM_031863               3711 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus centromere protein Q (Cenpq), mRNA.
ACCESSION   NM_031863
VERSION     NM_031863.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3711)
  AUTHORS   Tian,T., Chen,L., Dou,Z., Yang,Z., Gao,X., Yuan,X., Wang,C.,
            Liu,R., Shen,Z., Gui,P., Teng,M., Meng,X., Hill,D.L., Li,L.,
            Zhang,X., Liu,X., Sun,L., Zang,J. and Yao,X.
  TITLE     Structural insights into human CCAN complex assembled onto DNA
  JOURNAL   Cell Discov 8 (1), 90 (2022)
   PUBMED   36085283
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3711)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3711)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   4  (bases 1 to 3711)
  AUTHORS   Wilkemeyer,M.F., Andrews,E.R. and Ledley,F.D.
  TITLE     Genomic structure of murine methylmalonyl-CoA mutase: evidence for
            genetic and epigenetic mechanisms determining enzyme activity
  JOURNAL   Biochem J 296 (Pt 3) (Pt 3), 663-670 (1993)
   PUBMED   7904153
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY078791.1, AK076094.1 and AC121932.2.
            
            On Feb 13, 2019 this sequence version replaced NM_031863.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012179.1, AK076094.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on expression, longest
                                                protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-46                BY078791.1         2-47
            47-1461             AK076094.1         2-1416
            1462-3711           AC121932.2         30277-32526
FEATURES             Location/Qualifiers
     source          1..3711
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.55 cM"
     gene            1..3711
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /note="centromere protein Q"
                     /db_xref="GeneID:83815"
                     /db_xref="MGI:MGI:1933744"
     exon            1..192
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            193..327
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             229..1032
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /note="CENP-Q"
                     /codon_start=1
                     /product="centromere protein Q"
                     /protein_id="NP_114069.2"
                     /db_xref="CCDS:CCDS28789.1"
                     /db_xref="GeneID:83815"
                     /db_xref="MGI:MGI:1933744"
                     /translation="MSGKARASRKKPQQVKRSLKQRANKEADLPENEVGNTAKRNRSH
                     AKHLSSKVTGQATYVHLKRVKISSSKRTTWQPLPKDTEEYLQSMMESVILGILFNIKR
                     KEEIQCHLNQLKKRLLQQCATLKVPPRKLNYLKDVSKMLKMEKAQERANEESLASLQE
                     EIDKIVETTESMTESIQSLKNKIQILTSEVEEEEQEVKQVFHIDSNKVLALPELSQKS
                     LKAPILQEEILALIPNQNALLKDLDVLHDSAPVKNVSAFIEEAYKKLDS"
     exon            328..382
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            383..509
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            510..575
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            576..705
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            706..825
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            826..903
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            904..3711
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1438..1443
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1464
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /note="major polyA site"
ORIGIN      
        1 acacaagtgt gtttgcgttc ctcactgacg cttccggttc ccagatcctg gaagttctcc
       61 gtcttttccg gttgtttggg cggattaagt cagaagcgcg ccttttgaat ccgtgaagca
      121 actgtgaaga gtcgaggaag cgataaagcg gctgacagat ccaggggata atttgagcct
      181 cacgcgtttg tgactatgta tcgttgtgat tatactgttt agatgaaaat gtctggtaaa
      241 gcacgtgctt ctaggaaaaa acctcaacag gtgaaaagaa gtttgaaaca aagagccaat
      301 aaggaagcgg atttgccaga gaatgaggtt ggaaacacag caaaaagaaa cagaagtcat
      361 gcaaagcatc tgtcctctaa agtaacagga caagcaacgt atgttcatct aaaacgggta
      421 aaaatatcat ccagcaagag aacaacctgg caacctcttc caaaggatac tgaagagtat
      481 ttgcaaagta tgatggagtc agtcattctt ggaattttat tcaacataaa aagaaaagaa
      541 gaaattcagt gtcatctcaa ccagttgaag aaaagactac tacaacaatg tgcaacactg
      601 aaagtccctc caagaaagtt gaactattta aaggatgtgt caaaaatgct gaaaatggaa
      661 aaggcacagg aaagagcaaa tgaagagagc ctggcttcac tgcaggaaga aatagacaaa
      721 atagtagaga ccacagagtc aatgactgag agtattcaaa gcctaaagaa taaaattcaa
      781 attttgacaa gtgaagtaga agaagaggaa caggaggtga aacaggtatt tcacatagat
      841 agcaataaag tacttgctct tccagaactt tctcagaaaa gtcttaaagc acccatactt
      901 caagaagaaa ttttggcact aattccaaac cagaatgctc ttctgaagga cttggatgtt
      961 cttcatgatt cagccccagt gaagaatgtg tcagcattca ttgaagaagc ctataagaaa
     1021 cttgactcct aaagagttgg attttgtttt ggtgtttaag ccgtgttcca tattaactta
     1081 ttgttgataa attgtaaaac tcttttttct tttagtaata gtctctcact ctgtttgtag
     1141 cctaggctgg ctcagcactt attctttctc ccatttggcc ttgaactccc agcaatcctg
     1201 cctcagcatc ctgagtgctg ggattaccgg ggcgagcttc acatctggcc caaaggtgtg
     1261 caacttaact ggagatcttt cttcaaaaca attaaccttt gttatctacc ttaaaactag
     1321 cctgtgtggg cttatcatta atatctaatg tcctataaac attgcagttg ctaaatctag
     1381 gaaatttata tatatgtaga tatttgctaa aactgtttac tgagaattat ttttaaaaat
     1441 aaaaaaaaaa atgccatgat gtaatagttt ctgatgtgtg agtagaactt tttattggaa
     1501 gtcattttgt ggctatgaag agtgggtgta cagcacctac ttgatagaaa cattagtatc
     1561 tctctcttta ctttgactgg tagccttcat tttctgtcca atcatgtgga atttgaaaaa
     1621 tctcaaatgc cttcttaaat ctctcatctc tatgcaattc ttgctatttt tttcaggtgt
     1681 ttttgcacta acgataataa catgctggtt ctttggctag agaattgtta ggtgctggat
     1741 actttctgct ccaccaaagc atactctttg tatgtttaaa gattgtttaa agggaacctg
     1801 agtacatata tcctatcaga taaaagcaaa acaaacaaca gaaaactttt ttggaaaagc
     1861 ccagtattgg acaagtgacc accgccaaag gtagaaagaa ctggggaagg gctgcagagt
     1921 agggttaaaa atgaaaatat gtgagacttg caggcaagag catggttgtt cgcttaacag
     1981 gaggatccta acactgtgca gtgcaaagaa aggctgctat cctaagctcc acaaatgtga
     2041 accacagcta accaaaatgt tcttgcgctt tgtgagaaac tgttaggagt ttctcatgcc
     2101 gtgtcaatta tgagacagcc tggtgtctca taactcaagc tgcattcctg ctaagcatct
     2161 tctcataaac cttgtgaagt ttatatatgt gaagaaatat ttccataagc aggtctgaaa
     2221 tcatctctaa ccaacagtag tacattgatt tggagtgggt agtacattag cttggatttt
     2281 gttatctact tataattgca gttgaatttt tttaagattt atttatttta tgtatgagta
     2341 cactgttgct gtcttcagac acaccagaag agggcatcag atcccattac aaatggttgt
     2401 gaatcaccat gtagttgctg ggaattgaac tcacgacttg tggaagagca tccaatgctc
     2461 ttaacagcag agccatctct ccagccctaa attttctatc gtactaaaga atttttgtta
     2521 gcttatttag gaaattccat aatgctgcta atatctccca aacagaactt cctgtttacc
     2581 tatggttaac tatcttggga ttgatatctg ctgtagaggg aggtcatggc tttggaatcc
     2641 tggagctgct tgagcccaaa gaatcagaag cagggtcatc ttaggaaggt taggaagact
     2701 ttagaaaagt aatagatttc cacaggttgc cttaaaaccc tgcgctcagc aactgaaaac
     2761 ttggttcttt tagactaata gaatgctaag tcattggttt ttatcattag ctagaacatt
     2821 tacactagca tactgttttc ctcaggatat ctacttgata gttaatatca agtcaactag
     2881 aatatcagtt tatcattaca actgaatgat agtcacctca tttccacggc agaactgcta
     2941 cctcctagct ttggaagtat agcctttaac ttagagctat gctacactcc aggacttaac
     3001 aggtaatcaa aaacagcttt tctttaaatg ctttattttt ggcatccttt ttgtgaatga
     3061 tttgaggtaa atctacagct aatatccttt gtccccaagt agatgctaag tagataaggt
     3121 gtgagtgaac agcaggtgtc agtgtagaaa ttgcctggtc ttagcaaaca aagacaatgc
     3181 tgtaatgaaa gcaggtaatt atatggagct ctgatggatt tgtaaaagag ccaagccaaa
     3241 tactgagcca caacagagtg gaaaacggag cagtcattaa acaaagccct aatatataat
     3301 gaactgcaaa agaggtgtac attaaatacc aagagaaaat gggttaattc ttgaaaggaa
     3361 aggtttaaaa gctatgaaat gcttgcataa tattcaatct tataatgatc acttagacat
     3421 agaaactaag tgctttcacc agttaggttt gtgaatattt aaaagtgaaa cgtgttgaat
     3481 taactcctag ggaaataaat gttaagtaaa ctgccaaagg acagtaattt ggtataacca
     3541 ttttggggaa catgctacac aagtaagttg tagcctccat gtcggccatt tacattcttt
     3601 atataagctt ctctattacc tgccaactct gtttgcatat cttcaataat taggctctgt
     3661 tatgtgaaac acctgcagta gaacctacga ttaaaggatt tattttactt g
//
