LOCUS       NP_114069                267 aa            linear   ROD 28-APR-2025
DEFINITION  centromere protein Q [Mus musculus].
ACCESSION   NP_114069
VERSION     NP_114069.2
DBSOURCE    REFSEQ: accession NM_031863.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 267)
  AUTHORS   Tian,T., Chen,L., Dou,Z., Yang,Z., Gao,X., Yuan,X., Wang,C.,
            Liu,R., Shen,Z., Gui,P., Teng,M., Meng,X., Hill,D.L., Li,L.,
            Zhang,X., Liu,X., Sun,L., Zang,J. and Yao,X.
  TITLE     Structural insights into human CCAN complex assembled onto DNA
  JOURNAL   Cell Discov 8 (1), 90 (2022)
   PUBMED   36085283
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 267)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 267)
  AUTHORS   Powles,N., Babbs,C., Ficker,M., Schimmang,T. and Maconochie,M.
  TITLE     Identification and analysis of genes from the mouse otic vesicle
            and their association with developmental subprocesses through in
            situ hybridization
  JOURNAL   Dev Biol 268 (1), 24-38 (2004)
   PUBMED   15031102
REFERENCE   4  (residues 1 to 267)
  AUTHORS   Wilkemeyer,M.F., Andrews,E.R. and Ledley,F.D.
  TITLE     Genomic structure of murine methylmalonyl-CoA mutase: evidence for
            genetic and epigenetic mechanisms determining enzyme activity
  JOURNAL   Biochem J 296 (Pt 3) (Pt 3), 663-670 (1993)
   PUBMED   7904153
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY078791.1, AK076094.1 and AC121932.2.
            
            On Feb 13, 2019 this sequence version replaced NP_114069.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012179.1, AK076094.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on expression, longest
                                                protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.55 cM"
     Protein         1..267
                     /product="centromere protein Q"
                     /note="CENP-Q"
                     /calculated_mol_wt=30370
     Region          1..54
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9CPQ5.2)"
     Site            49
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q7L2Z9; propagated from
                     UniProtKB/Swiss-Prot (Q9CPQ5.2)"
     Region          117..266
                     /region_name="CENP-Q"
                     /note="a CENPA-CAD centromere complex subunit; pfam13094"
                     /db_xref="CDD:432970"
     CDS             1..267
                     /gene="Cenpq"
                     /gene_synonym="2610528M18Rik"
                     /coded_by="NM_031863.4:229..1032"
                     /db_xref="CCDS:CCDS28789.1"
                     /db_xref="GeneID:83815"
                     /db_xref="MGI:MGI:1933744"
ORIGIN      
        1 msgkarasrk kpqqvkrslk qrankeadlp enevgntakr nrshakhlss kvtgqatyvh
       61 lkrvkisssk rttwqplpkd teeylqsmme svilgilfni krkeeiqchl nqlkkrllqq
      121 catlkvpprk lnylkdvskm lkmekaqera neeslaslqe eidkivette smtesiqslk
      181 nkiqiltsev eeeeqevkqv fhidsnkvla lpelsqkslk apilqeeila lipnqnallk
      241 dldvlhdsap vknvsafiee aykklds
//
