LOCUS       NM_001159930            2327 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus centromere protein L (Cenpl), transcript variant 1,
            mRNA.
ACCESSION   NM_001159930
VERSION     NM_001159930.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2327)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2327)
  AUTHORS   Tian,T., Chen,L., Dou,Z., Yang,Z., Gao,X., Yuan,X., Wang,C.,
            Liu,R., Shen,Z., Gui,P., Teng,M., Meng,X., Hill,D.L., Li,L.,
            Zhang,X., Liu,X., Sun,L., Zang,J. and Yao,X.
  TITLE     Structural insights into human CCAN complex assembled onto DNA
  JOURNAL   Cell Discov 8 (1), 90 (2022)
   PUBMED   36085283
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2327)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2327)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2327)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DV649208.1, BC116944.1, BC060191.1 and BC063765.1.
            
            On Mar 5, 2015 this sequence version replaced NM_001159930.1.
            
            Transcript Variant: This variant (1) encodes the protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC080823.1, SRR5189673.166955.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-697               DV649208.1         1-697
            698-1754            BC116944.1         499-1555
            1755-1910           BC060191.1         4185-4340
            1911-2327           BC063765.1         1604-2020
FEATURES             Location/Qualifiers
     source          1..2327
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 69.75 cM"
     gene            1..2327
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /note="centromere protein L"
                     /db_xref="GeneID:70454"
                     /db_xref="MGI:MGI:1917704"
     exon            1..590
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            591..764
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /inference="alignment:Splign:2.1.0"
     CDS             594..1631
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /codon_start=1
                     /product="centromere protein L"
                     /protein_id="NP_001153402.1"
                     /db_xref="CCDS:CCDS48413.1"
                     /db_xref="GeneID:70454"
                     /db_xref="MGI:MGI:1917704"
                     /translation="MDSCDFRGLTSRRRTSNLKNYFVGATPLQKRLELVRRQNSDFPS
                     PSRRKIPQCSQLQEDIDPQKVAFLLHKQWTIYSLTPLYKFSYSNLKDYSRLLSAFIVA
                     EKQKGVAVEVGEDFNIKVIFSTLLGVKGTQRDHEAFLVQILSKSQSSREHREDKVLWT
                     GWFCCVFGESLQETVSEDFTCLPLFLANGAESNTSLIRDWFQKTFDCCFSPLAISAFN
                     LSWMAAMWTACKMDRYMATTEFLWSVPCSPQSLDISYAIHPEDAKALWESVHKTPGEV
                     TQEEVDLFMNCLYSHFHRHFKIHLAATRLVRVSTSVASAHTDGKIKILCHKYLIGVLA
                     YMTELAIFQIE"
     exon            765..1016
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1559
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /inference="alignment:Splign:2.1.0"
     exon            1560..2296
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1880..1885
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /note="hexamer: AATAAA"
     polyA_site      1910
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /note="major polyA site"
     regulatory      2273..2278
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
                     /note="hexamer: AATACA"
     polyA_site      2296
                     /gene="Cenpl"
                     /gene_synonym="2610300B10Rik; CENP-L"
ORIGIN      
        1 gaacaacgcg gcgcaatagg ggattgggaa tttgaggcta ttgattgaag ccttccaagc
       61 cttgccctca gttaaaatga cgacttcagt tgctttcagt tacgtgaaat cggagggcca
      121 caggcgaggc tttccgagtc ggccgcaggg caagtcggga aatgatttta aactggaggg
      181 cgtggcgtgt gtggaaaagc gcctagacga gcggaacttt caagtctacc tttgatcccc
      241 ggagagctcc ggagaagggt ctttggggac tccctgtttt tcgtgggccg gcgccagctt
      301 ccgaagagcg aggatcatag agccgggcag cttgggaagc cgagctgtct ctcccggggg
      361 aagtcgcagg tcttgctcga gcctgaggga agctaggttc actccaggac tcctgatgtc
      421 tcttctgaac tcaccgggga ttgcttcggt tctctcttaa gcagtcattt tggccacttt
      481 cttcttctta aaaaaccaaa acctttcgtc tcgacgtagt cttggagcaa aacttgaagg
      541 atgattcgtg aatccggagt ggatgacagt gtctttacga catagttttg accatggatt
      601 cctgtgattt tcgaggactg acttctagac gaaggacctc aaatcttaag aactactttg
      661 taggtgccac ccctctgcag aaacgactgg aattggtcag gaggcagaat tcagattttc
      721 ccagtccatc tcgaaggaaa attccccagt gttcacagtt gcaggaagat atcgatcctc
      781 agaaggttgc atttctcctc cacaaacagt ggactatata tagtttaact cccttgtata
      841 aattctccta ttctaatctc aaagactatt ctagacttct aagtgcattt attgttgccg
      901 aaaagcaaaa aggagtagct gtggaagtgg gagaagactt caacatcaaa gtgattttct
      961 ccactctact tggagtgaaa gggacacaaa gggaccatga agcgtttctt gtccagattc
     1021 tctcaaaatc tcagtcatca cgtgaacaca gagaagataa agtgttgtgg actggttggt
     1081 tctgttgtgt gtttggagag agtcttcagg agactgtctc agaagacttc acctgtctac
     1141 ccttattcct tgcaaatgga gcggagtcca atacatcttt aatcagagac tggtttcaga
     1201 aaacctttga ctgttgcttc agtcctttag caatcagtgc gtttaatctt tcctggatgg
     1261 ctgctatgtg gacagcatgc aaaatggacc gttatatggc tactactgaa tttctttggt
     1321 ctgtgccctg tagcccacag agcttagata tttcttatgc aatacatcca gaagatgcaa
     1381 aagctttatg ggaaagtgtc cacaaaaccc ctggggaggt tacccaggag gaagttgact
     1441 tatttatgaa ctgcctttat tcacatttcc ataggcattt caaaattcac ttagcagcca
     1501 caagattggt tcgtgtctca acatctgtag cttcagcaca cactgatggg aaaataaaga
     1561 ttctgtgtca taaatacctt attggtgtgt tggcatatat gacagaactg gcaatttttc
     1621 aaattgaatg aatttttgta tggactaagt gatgcattat aaactgtttt gatcatttgc
     1681 tgaactgcga tgccaagtgg gacagtggaa gaaatggagc acttgtctca gggtgcctct
     1741 ggagttgccc agatggatat agaacatagt ggtagtgggt gagccgcgtt catgggcttg
     1801 tgtatccagc atatcactgt ggctgtgtcc tgttataaaa gatgctgaat tgttaatata
     1861 aaaggatcca atttagtcaa ataaacttac ctaaaatctg gtgtttccaa ttgaagttat
     1921 ttattctgtt agtggggctt gcctctgagg ttccttcctg acttccttga tttttcacct
     1981 ctagatttcc ctcagtttgg ttttttgatt ctctttccac tttcatgtct tgaactgttt
     2041 tattaatttc tttctactgt ttgtgtcttt catagagtta aggattaatt ccctttttta
     2101 aagacctcta ccatattcat aagtgctatt ttaaggtctt ttgtcttgtg tttcagctat
     2161 gttgtaattc tcagggccta ctgtggtagg ttgctgggct ctagtggaga cattgtgtcc
     2221 tggctgttac tgagtatatt tttatgatgg catctgggtt tgggaagagt gtaatacatg
     2281 atgttgatat tcataaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
