LOCUS       NM_001357784            3135 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus CUGBP, Elav-like family member 3 (Celf3), transcript
            variant 6, mRNA.
ACCESSION   NM_001357784 XM_006502325
VERSION     NM_001357784.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3135)
  AUTHORS   Shen,C.L., Tsai,Y.Y., Chou,S.J., Chang,Y.M. and Tarn,W.Y.
  TITLE     RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar
            foliation
  JOURNAL   Commun Biol 7 (1), 1712 (2024)
   PUBMED   39738787
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3135)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3135)
  AUTHORS   Kaiser,M., Wojahn,I., Rudat,C., Ludtke,T.H., Christoffels,V.M.,
            Moon,A., Kispert,A. and Trowe,M.O.
  TITLE     Regulation of otocyst patterning by Tbx2 and Tbx3 is required for
            inner ear morphogenesis in the mouse
  JOURNAL   Development 148 (8) (2021)
   PUBMED   33795231
REFERENCE   4  (bases 1 to 3135)
  AUTHORS   Ishizuka,A., Hasegawa,Y., Ishida,K., Yanaka,K. and Nakagawa,S.
  TITLE     Formation of nuclear bodies by the lncRNA Gomafu-associating
            proteins Celf3 and SF1
  JOURNAL   Genes Cells 19 (9), 704-721 (2014)
   PUBMED   25145264
REFERENCE   5  (bases 1 to 3135)
  AUTHORS   Osipovich,A.B., Long,Q., Manduchi,E., Gangula,R., Hipkens,S.B.,
            Schneider,J., Okubo,T., Stoeckert,C.J. Jr., Takada,S. and
            Magnuson,M.A.
  TITLE     Insm1 promotes endocrine cell differentiation by modulating the
            expression of a network of genes that includes Neurog3 and Ripply3
  JOURNAL   Development 141 (15), 2939-2949 (2014)
   PUBMED   25053427
REFERENCE   6  (bases 1 to 3135)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   7  (bases 1 to 3135)
  AUTHORS   Dev,A., Nayernia,K., Meins,M., Adham,I., Lacone,F. and Engel,W.
  TITLE     Mice deficient for RNA-binding protein brunol1 show reduction of
            spermatogenesis but are fertile
  JOURNAL   Mol Reprod Dev 74 (11), 1456-1464 (2007)
   PUBMED   17393433
  REMARK    GeneRIF: Brunol1 might be nonessential protein for mouse embryonic
            development and spermatogenesis.
REFERENCE   8  (bases 1 to 3135)
  AUTHORS   Li,H., Bishop,K.M. and O'Leary,D.D.
  TITLE     Potential target genes of EMX2 include Odz/Ten-M and other gene
            families with implications for cortical patterning
  JOURNAL   Mol Cell Neurosci 33 (2), 136-149 (2006)
   PUBMED   16919471
REFERENCE   9  (bases 1 to 3135)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122808.3 and BC057553.1.
            
            On Nov 10, 2017 this sequence version replaced XM_006502325.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219382.33323.1,
                                           SRR17784647.1081980.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-786               AC122808.3         57402-58187         c
            787-869             AC122808.3         56303-56385         c
            870-918             AC122808.3         51788-51836         c
            919-1047            AC122808.3         51252-51380         c
            1048-1127           AC122808.3         51077-51156         c
            1128-1271           AC122808.3         49986-50129         c
            1272-1413           AC122808.3         49718-49859         c
            1414-1563           AC122808.3         49369-49518         c
            1564-1629           AC122808.3         48801-48866         c
            1630-1770           AC122808.3         48374-48514         c
            1771-1914           AC122808.3         47983-48126         c
            1915-2051           AC122808.3         47046-47182         c
            2052-3116           AC122808.3         44456-45520         c
            3117-3135           BC057553.1         3174-3192
FEATURES             Location/Qualifiers
     source          1..3135
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 40.73 cM"
     gene            1..3135
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /note="CUGBP, Elav-like family member 3"
                     /db_xref="GeneID:78784"
                     /db_xref="MGI:MGI:1926034"
     exon            1..786
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     CDS             642..2042
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /note="isoform 5 is encoded by transcript variant 6;
                     trinucleotide repeat containing 4; CUG-BP- and ETR-3-like
                     factor 3; bruno-like protein 1; RNA-binding protein
                     BRUNOL-1; ELAV-type RNA-binding protein 1; trinucleotide
                     repeat-containing gene 4 protein; VCUGBP, Elav-like family
                     member 3"
                     /codon_start=1
                     /product="CUGBP Elav-like family member 3 isoform 5"
                     /protein_id="NP_001344713.1"
                     /db_xref="GeneID:78784"
                     /db_xref="MGI:MGI:1926034"
                     /translation="MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYT
                     GLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGML
                     GKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRT
                     LPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAAL
                     VAAHSAYLSPMATMAAVQMQHMAAISANGLIATPITPSSGTSTPPAIAATPVSAIPAA
                     LGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPA
                     AYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEF
                     TDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMK
                     RLKVQLKRPKDANRPY"
     exon            787..869
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            870..918
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            919..1047
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1127
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1271
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1272..1413
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1563
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1629
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1770
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1771..1914
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1915..2051
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..3117
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3089..3094
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /note="hexamer: AATAAA"
     regulatory      3093..3098
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /note="hexamer: AAGAAA"
     polyA_site      3101
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
                     /note="major polyA site"
     polyA_site      3113
                     /gene="Celf3"
                     /gene_synonym="4930415M08Rik; BRUNOL1; CAGH4; ERDA4;
                     ETR-1; Tnrc4"
ORIGIN      
        1 ggtctaggga gaacctgaag gggacagggc agaagggacc cccgaagccc tgccgccatc
       61 agagatcaag catttggcat cagggatctt cggacccagc agaaggatca gccacaggga
      121 ggtgtcttcc ctaggaagcc aacgagagag tcacctgccc cacatcagga gcagggaccc
      181 cctcatgacg ctgctggcaa ccatagcagt cccctagccc ctcagcctct ttcctatcgc
      241 cctcttctga ctttacccca tctcctttgg catctgtgcc tttgctcccg ccctctgagc
      301 tccaccgttc cagctaccac ccaaacgccc cagggtttgg tcaccctgac cctcagcctg
      361 ggatatttgc cagatctctg ggagggagat cctttgcttg ggctatgccc ctggtggcct
      421 gacactgtct gcctagaccc ctgaccccta gccctcaact ccccaggcct cctttgtgtg
      481 aagagccctc ctctgctcag cagtgtggtt gggggccaaa ggaaaagctg gccctgctgg
      541 gcccctgggc cctaccacct gcctcctggt tgggcagctt cccttgtctt tggtcctctc
      601 cctgctcccc cacccccggc ccctcctcct gggccgcccc aatgaaggag ccagatgcca
      661 tcaagctgtt tgtggggcag atcccgaggc atctggagga aaaggacctg aagcccatct
      721 tcgagcagtt tggtcggatc ttcgagctga ctgtcatcaa ggacaagtac accgggctgc
      781 acaagggatg tgctttcctg acgtactgtg ctcgcgattc agccctgaag gcccagagtg
      841 ccctgcacga acagaagact ctcccaggga tgaacaggcc gatccaggtc aagccagccg
      901 acagcgagag tcgaggagaa gaccggaagc tctttgtggg catgctagga aagcagcaga
      961 cagatgagga tgtccggaag atgtttgaac catttgggac tatagacgag tgcactgtgc
     1021 tccgggggcc agacggtacc agcaaaggct gtgcctttgt gaagttccag actcacgctg
     1081 aggcccaggc agccatcaac acccttcaca gcagccggac cctaccgggt gcctcatcca
     1141 gcctggtggt aaagtttgct gacacggaga aggagcgagg tctccgtcga atgcagcagg
     1201 tggctaccca gctgggcatg ttcagcccga tcgccctcca gtttggagcc tacagcgcct
     1261 acacccaggc cctgatgcag cagcaggcgg ccctggtagc agctcacagt gcctacctca
     1321 gccctatggc caccatggct gccgtgcaga tgcagcacat ggctgccatc agtgccaatg
     1381 gcctcatcgc cacccccatc actccatcct caggaaccag cacccctcct gccattgctg
     1441 ccacgcccgt ctctgccatc cctgctgcct tgggcgtcaa cggctacagc ccggtgccca
     1501 cccagcctac agggcagcct gccccggatg ctctgtatcc caacggggtt cacccttacc
     1561 cagcccagag cccggcagcc cccgtggacc ctctccagca ggcctatgca ggaatgcagc
     1621 actacacagc agcgtacccc gcagcctaca gcctggttgc acctgcgttc ccgcagcctc
     1681 cagccctggt tgcccagcag cccccaccac cacctcagca acagcagcag cagcagcagc
     1741 agcaacagca acagcagcag caacgggaag gccctgatgg ctgcaacatc ttcatctacc
     1801 acctgcccca ggagttcaca gactcagaga tcctccagat gtttgtccct tttggtcatg
     1861 tcatctcagc caaagtcttt gttgaccggg ccaccaatca gagcaaatgt tttggctttg
     1921 tgagtttcga caatccggcc agtgcccagg ctgccatcca ggctatgaac ggtttccaga
     1981 ttggcatgaa gcgcctcaaa gtccagctaa agcggcctaa ggatgcaaac aggccctact
     2041 aagggcttca ggtctggaga taccagagga aggggcactt cagtataccc tcttcctatg
     2101 actggccctg gccttctctg cacatctgcc ccaggccttg attggactct ggggcaagag
     2161 ctgcttcatg gtccgagggc ccaggacctg gctcactccc accatcttgc ctctctgaag
     2221 ggccatggtt ttgcttccct ggcttcaaga gcctatttcc tccccagtgc ccttttggcc
     2281 tttgtgagga agcaaggaat aggcttgaag gttcaggggc atctgccttc tgctaaggct
     2341 cctggatgag cctctgtgcc cactgctggc ccttgcctcc cctcagtggc ctgcagtagc
     2401 tgtgcaggct cggaagggca gcaggacact ctcctctttc ccaagcaccc tcccccttgc
     2461 ctctccccac ggcagggcct tctcagaagc cctgccttct cagaagctgg ctcccacgtt
     2521 tctccccacc ctcagctaga ggtaggagat ctccaaaccc cgggctctca gccctaaaac
     2581 tcactgcctt ccccaagagc cccctccaag gagggtgtgt gtgtgggggg gggggggcct
     2641 gagggctgcc tctctgccag tcagtcacag agaccctcct ttcatgagga aaagacctct
     2701 ccctgagtcc ctaaatatgt ttacagtctc tgctggcccc tccatgtaaa taccatgacc
     2761 accagggctt taatcagccc acccagccag acgctgccat ctctctttct gggagtttag
     2821 acaatgctgc ccttggattt tgtttttttc tttttttcct ctcttgattt ctccctttgc
     2881 tttgggggta attgggtatt tgggggaagg gtatggggag ggctaaaggg gtttattacc
     2941 tgatcatttt ctttaggaag aggttctagg gaaaaaaaca tggggtgggg tggggagggt
     3001 aaaggataag aagggggaat caatttctga cagttctcta ctcttattta ttgagtttta
     3061 cttttaaaga gttggtcttt tctgtctaaa taaagaaaaa acatttgaaa gcatcaaaaa
     3121 aaaaaaaaaa aaaaa
//
