LOCUS       NM_001406847            7565 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus CUGBP, Elav-like family member 2 (Celf2), transcript
            variant 20, mRNA.
ACCESSION   NM_001406847
VERSION     NM_001406847.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7565)
  AUTHORS   Huang,P., Meng,L., Pang,J., Huang,H., Ma,J., He,L. and Lin,X.
  TITLE     miR-208a-3p regulated by circUQCRC2 suppresses
            ischemia/reperfusion-induced acute kidney injury by inhibiting
            CELF2-mediated tubular epithelial cell apoptosis, inflammation and
            ferroptosis
  JOURNAL   Shock 61 (6), 942-950 (2024)
   PUBMED   38664873
  REMARK    GeneRIF: miR-208a-3p regulated by circUQCRC2 suppresses
            ischemia/reperfusion-induced acute kidney injury by inhibiting
            CELF2-mediated tubular epithelial cell apoptosis, inflammation and
            ferroptosis.
REFERENCE   2  (bases 1 to 7565)
  AUTHORS   Guo,T., Wang,Y., Sun,X., Hou,S., Lan,Y., Yuan,S., Yang,S., Zhao,F.,
            Chu,Y., Ma,Y., Cheng,T., Yu,J., Liu,B., Yuan,W. and Wang,X.
  TITLE     Loss of RNA-binding protein CELF2 promotes acute leukemia
            development via FAT10-mTORC1
  JOURNAL   Oncogene 43 (19), 1476-1487 (2024)
   PUBMED   38514854
  REMARK    GeneRIF: Loss of RNA-binding protein CELF2 promotes acute leukemia
            development via FAT10-mTORC1.
REFERENCE   3  (bases 1 to 7565)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 7565)
  AUTHORS   Salamon,I., Park,Y., Miskic,T., Kopic,J., Matteson,P., Page,N.F.,
            Roque,A., McAuliffe,G.W., Favate,J., Garcia-Forn,M., Shah,P.,
            Judas,M., Millonig,J.H., Kostovic,I., De Rubeis,S., Hart,R.P.,
            Krsnik,Z. and Rasin,M.R.
  TITLE     Celf4 controls mRNA translation underlying synaptic development in
            the prenatal mammalian neocortex
  JOURNAL   Nat Commun 14 (1), 6025 (2023)
   PUBMED   37758766
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7565)
  AUTHORS   Qu,F., Li,W., Xu,J., Zhang,R., Ke,J., Ren,X., Meng,X., Qin,L.,
            Zhang,J., Lu,F., Zhou,X., Luo,X., Zhang,Z., Wang,M., Wu,G., Pei,D.,
            Chen,J., Cui,G., Suo,S. and Peng,G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7565)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (bases 1 to 7565)
  AUTHORS   Zhang,W., Liu,H., Han,K. and Grabowski,P.J.
  TITLE     Region-specific alternative splicing in the nervous system:
            implications for regulation by the RNA-binding protein NAPOR
  JOURNAL   RNA 8 (5), 671-685 (2002)
   PUBMED   12022233
  REMARK    GeneRIF: NAPOR may be one of a group of closely related proteins
            involved in splicing regulation within the brain.
REFERENCE   8  (bases 1 to 7565)
  AUTHORS   Ladd,A.N., Charlet,N. and Cooper,T.A.
  TITLE     The CELF family of RNA binding proteins is implicated in
            cell-specific and developmentally regulated alternative splicing
  JOURNAL   Mol Cell Biol 21 (4), 1285-1296 (2001)
   PUBMED   11158314
REFERENCE   9  (bases 1 to 7565)
  AUTHORS   Choi,D.K., Ito,T., Tsukahara,F., Hirai,M. and Sakaki,Y.
  TITLE     Developmentally-regulated expression of mNapor encoding an
            apoptosis-induced ELAV-type RNA binding protein
  JOURNAL   Gene 237 (1), 135-142 (1999)
   PUBMED   10524244
REFERENCE   10 (bases 1 to 7565)
  AUTHORS   Lu,X., Timchenko,N.A. and Timchenko,L.T.
  TITLE     Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG
            repeats expanded in myotonic dystrophy
  JOURNAL   Hum Mol Genet 8 (1), 53-60 (1999)
   PUBMED   9887331
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772190.6, AL845492.10 and AL845515.5.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253014.5400904.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849374,
                                           SAMN00849375 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               AL772190.6         80634-80800
            168-203             AL772190.6         199493-199528
            204-394             AL845492.10        167533-167723       c
            395-477             AL845492.10        110225-110307       c
            478-526             AL845492.10        70781-70829         c
            527-661             AL845492.10        61798-61932         c
            662-741             AL845492.10        53992-54071         c
            742-900             AL845492.10        50134-50292         c
            901-964             AL845492.10        46144-46207         c
            965-1099            AL845492.10        32084-32218         c
            1100-1231           AL845492.10        6769-6900           c
            1232-1411           AL845515.5         135326-135505       c
            1412-1583           AL845515.5         128583-128754       c
            1584-7565           AL845515.5         121235-127216       c
FEATURES             Location/Qualifiers
     source          1..7565
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 3.69 cM"
     gene            1..7565
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /note="CUGBP, Elav-like family member 2"
                     /db_xref="GeneID:14007"
                     /db_xref="MGI:MGI:1338822"
     exon            1..167
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..1539
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /note="isoform 26 is encoded by transcript variant 20; CUG
                     triplet repeat, RNA binding protein 2; CUG-BP- and
                     ETR-3-like factor 2; bruno-like protein 3; RNA-binding
                     protein BRUNOL-3; neuroblastoma apoptosis-related
                     RNA-binding protein; elav-type RNA-binding protein 3;
                     mNapor"
                     /codon_start=1
                     /product="CUGBP Elav-like family member 2 isoform 26"
                     /protein_id="NP_001393776.1"
                     /db_xref="GeneID:14007"
                     /db_xref="MGI:MGI:1338822"
                     /translation="MVSLISDLDSLRGWKALRETATELSGSPPSNGTANKMNGALDHS
                     DQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSCCFVTFYT
                     RKAALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRV
                     MFSPFGQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVK
                     FADTQKDKEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAF
                     SGIQQMAGMNALQLQNLATLAAAAAAAQTSATSTNANPLSSTSSALGALTSPVAASTP
                     NSTAGAAMNSLTSLGTLQGLAGATVGLNNINALAGTINSMAALNGGLGATGLTNGTAG
                     TMDALTQAYSGIQQYAAAALPTLYSQSLLQQQSAAGSQKEGFVSYDNPVSAQAAIQAM
                     NGFQIGMKRLKVQLKRSKNDSKPY"
     exon            168..203
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            204..394
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            395..477
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            478..526
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            527..661
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            662..741
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            742..900
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            901..964
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            965..1099
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1231
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1411
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1412..1583
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1584..7565
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5371..5376
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /note="hexamer: ATTAAA"
     polyA_site      5390
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /note="major polyA site"
     regulatory      7539..7544
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
                     /note="hexamer: AATAAA"
     polyA_site      7565
                     /gene="Celf2"
                     /gene_synonym="B230218O03; B230345P09Rik; CELF-2; CUG-BP2;
                     Cugbp2; D230046B21Rik; Etr-3; mETR-3; Napor; Napor-2"
ORIGIN      
        1 gctgctgggc gctgctgctc cggcctgagc ccagagccac ctctgcctgc gtccctgtcg
       61 ccctgtcagg cacctctgct ctccggtttg ccttctttcc gcagctctca gacaatggtt
      121 tccctaatct ctgacctgga ctccctgaga ggctggaaag cgttaagaga gactgccaca
      181 gagttatctg gaagtccacc aagtaacggc acagccaaca agatgaacgg agctttggat
      241 cattcagacc agccagaccc agatgccatt aagatgtttg tcggacagat ccctaggtcc
      301 tggtcggaaa aggagctgaa agaacttttt gagccttatg gagctgtcta ccagatcaac
      361 gtcctccggg accggagtca gaaccctccc cagagttgtt gtttcgtaac attttataca
      421 agaaaagctg cacttgaggc ccagaatgca ctgcacaata ttaaaacttt acctgggatg
      481 catcatccca ttcagatgaa acctgcagat agtgaaaagt caaacgctgt ggaagacaga
      541 aaattgttca taggaatggt ttccaagaaa tgtaacgaga atgatatcag agtgatgttt
      601 tctccattcg gtcagataga agaatgccgg attctccggg gacctgatgg gctgagtcga
      661 ggctgtgcgt ttgtcacatt ttctacaagg gcaatggcac agaatgcaat caaagccatg
      721 catcagtctc agaccatgga gggctgctct tcaccaatcg tggtgaagtt tgctgacact
      781 cagaaggaca aagagcaaag gcgcctccag cagcagcttg cacagcagat gcaacagctc
      841 aacactgcca cttgggggaa cctaacagga ctgggtggac ttaccccgca gtacctggcg
      901 cttctgcagc aggccacctc ctccagcaac ctgggtgcat tcagtggcat tcagcaaatg
      961 gctggcatga atgctttaca gttacagaat ctggcaacac tggctgctgc tgcagctgct
     1021 gctcaaacct cagccaccag caccaatgca aaccctctgt ctagcacaag cagtgccctg
     1081 ggagccctca caagccctgt ggctgcttca acccccaatt ccaccgctgg tgcggccatg
     1141 aattccttga cctctcttgg gactctacaa ggattggctg gagccactgt cggattgaat
     1201 aatattaatg cactagcagg taccataaac agtatggcgg ctctgaatgg aggacttggc
     1261 gccacaggct tgacgaatgg tacggctggc accatggacg ccctgaccca ggcctactca
     1321 ggaattcagc agtatgcggc agctgcactg cccactttgt acagccagag cttgctgcaa
     1381 cagcagagtg ctgcaggcag ccagaaggaa ggttttgtta gctatgacaa tccagtctct
     1441 gcacaagctg caatccaggc tatgaacggc tttcagatcg gcatgaaacg cttgaaggtg
     1501 cagctgaaac gctccaaaaa cgacagcaaa ccttactgat cctaacccca gaagctccct
     1561 gctcttattt tagctttctt aggacatctt catgcccgtt agtcatcgtt tgcctagcat
     1621 gtccctgtgg cgtctcaaaa acagtttcat cgtcccgtca ttgtttctga tgtctttctg
     1681 acctcacatc atatttggtt ctcctactga cctttgatct agttttgacc tttgaaattt
     1741 gcatgtgacc tcatctagct atgaattctg ggaagtcaat gtgaaaaaca ttgctgcatt
     1801 catgcaagac tgaaattatt agacaaatta tagaaaacaa aacctgtggc aaaaatgttt
     1861 ctttcttatt tttttttctt ttcataaaac agacttgaaa gtattacaca gggattggca
     1921 ttctgcccgg tcactggtga caatagcaat atgtgtccag ggacacagaa tgttggtttc
     1981 taacagacta cttccaaaaa cagtttgaga aaaaaaaaaa aactgtctga ttttaagtct
     2041 ctagaggtct gtaatagttt ttacattttt caggcagtgt aaagtttttt gataaggcca
     2101 ttttaggtgg ctcactttct cattaagata tatatataga accacttttt gtagattagt
     2161 ataagaaaaa tatttaccct gttttggggc aaatgctacc tatttgtgtc accttttgct
     2221 gaactgactc acagttagac aatccatggt ttaatgcaca tgaaattacc tatattttat
     2281 actgttccaa tgtacaggag aaaggctact gtaagctgcg tcatgttggt gcttctgtgg
     2341 attaagttgt gctctcatca caagtcttaa ggtcttaatg ttatttgttg ataagacaag
     2401 cttagaattg gtttacttaa aacaaaaaaa aaaaagaatt tcaaaaaaaa aagttgtttg
     2461 cttaaaaaaa aaaagttcat gtgagagaaa aaagaaaaaa aaagaaaaaa aaaaaactat
     2521 tccagactaa gttttgtgtt ggcctgagaa gcattggcgt cacttttttt tattgtggac
     2581 tattagatgt gtttgtgttc agcaaaatgt gatgttttgt tttttctttt aaagaaaaaa
     2641 gtgaaaacta tctagtgcca aattccaaag gtacttcctc cctagagctt cgcgtgtttc
     2701 ctgtgagaag tgatttgata acatggtatt ttattatgtg ttttgtataa atccctaata
     2761 tttaaaacaa acaaaaaaaa aaaaaaggtt acaaagtttg ttaacttgct attccgtggt
     2821 cttgttgcct gaaattgtta ttgtttgtta tttctctatg ctgttttttg taagacattg
     2881 tataagtgcc gtgtgtcact tttctaacct ctccacgtca atgctgtgac ggcagccctc
     2941 acaatgtatt ctcttcataa tatctggaaa cctctaaggt gagaaagtcc tgaactttta
     3001 accctttcta cccagagcta tctggaatgt tggtgacttt ttatactgtc atccttgggt
     3061 ttgttttggg gtgtttagat atttttttcc atttgtatct tctgagttat tttttgtttt
     3121 ttgagtcaca caccttccca aaaaaccctt aagtcttttt cctaaaccgt tttttatttt
     3181 cttttttatc ccctccttcc tatcaccctg tgctccttca gtttaaatat aagagactga
     3241 gtagaccctg ggaagggaaa aacaggtaga gcttagccct acacaaaccc taaagaccgt
     3301 gtctgctttt tgataagggt ttcatggtat gccctcgtgt acaatatttt tatacaccct
     3361 ggagttaaat ggctttttgg tggtccaatc tttcaagaag ttttactttt gtttcttaaa
     3421 cacccctatg taatgctgag tcagcctttg gctcgggatt ctcagacgca tgtggacacc
     3481 tgaatatgca aggtgtcttc ctgaaaagcc cacacatttc aagtggttgg ccatgtaaga
     3541 ggagatcagc tgctcttcac cacaattact accaaatact aggactagtt cctgctgttg
     3601 ctctcgaaag tgccatattc ctgagtctgg cttcatatga gcagatgtct tgttctgaca
     3661 gaccccaatg tcatgcctac agtccaaaca cacacccagc ctctgggaaa acacaccctg
     3721 caagcttctg gtctcagctc ccttttcctt cacaccctcc ctccatttga tttaatgtgt
     3781 gtgtgaatgt gatagccctg agatggaaag gattagcctc tcacaatgca aaaaaaaaaa
     3841 aaaaaaaaaa aagttccctc cttccagcac gcgcacttcc agtgacatga ttggtgttag
     3901 cccactgttt accactgccg gggccttcct tcatccttga gggctatttt gtactttctg
     3961 cagcactcag ctcactaaca gtgatcacac acattctcag tctctctatg gtggtgtgta
     4021 ggtacacgtg tagaaacaca agagaatacc agttgtattt catagaccat ctcgttcaca
     4081 atctatttag ttattaatga tataaatctc aaaaaaaaat cttgactttt ttttttcccc
     4141 ccatggaagc caactgccct ccttcctctt aacccacctg cggcccccgc agaggctcgg
     4201 gtcaggcagg tactttctgt tgagctcggt ttctgatttt gcaggcgacc aagaccgtcc
     4261 attgaggcga gggcttggtt ttgcatgttt cattgttaga aagttagcct tcctcagaga
     4321 cagactgtcc ttcctctctc agtatcaaaa ggaaacgctg caagggtgcg cagggcctgt
     4381 ttccggaaga caaaacacag ggaaactgca tttttaaaaa tcaagtgtaa agcatataga
     4441 cttttaaaac tcactcagag aactctgatc agatggcacc tccacggtgt gacaagttca
     4501 tctttccttc accgcagggg ttctagttcc ttggcttgtg ctactctgga atcatttact
     4561 gtttctgtct ttattatctt aagtgctaat taaaagaaaa taaaacttaa aaaaatgtag
     4621 tttcattacc ttttgaataa tgtcatacaa aaatgtattt gtgtttttgt gctgtgggaa
     4681 ttgttgtttg tagattaata ataccatttt gtttagaact acaaaatagt ttttaaatat
     4741 tgtctgagaa aagccaaagt taatgcaacc tagtggaaac tgtaagacca tttgagtatt
     4801 gtttctgttt tattgatgca tttggatttt gttgtttgat ggaatttgag ccaaaaaaca
     4861 aaaatgcagg ctttcctatt tctacaactg attgtactta cgcattttgt accagtggga
     4921 ttttttatac tggagattaa aaaaaaatgg aaatttttgt ggcttactct tgtgggcccc
     4981 ctgacaatga ctgatttcaa gtttgatttc tggttgatag gaagaaagtt gcttttcctt
     5041 taagaattaa aaactttggc ttgatttctt tttttccctt tgcttatatc tagcattaga
     5101 attttgtctt aaaatacagc ggtaagtttc actctttatt ctgtactgtg cagttacaca
     5161 ataagataat tagatttaga agtactcagt cactttaagt ggataaatgt attagttaaa
     5221 ctttaggagt ttgctttttt gctgtttaga tcgaagtttt ttctgaccct tctgtcctca
     5281 ttgtgaacat aaccgtgtag ttgaaacagt cagacttatt tttgtaatgt atgttattgt
     5341 gtgatgcggt tttttgcttc tgtctccaat attaaaccat tttcctaata cttgtttctc
     5401 tctctgcgtg ttgtattgtt ggtaatcatt ctgtgttggt gacacatcta cacaacctca
     5461 ctgttgcacg tatctgttct tttctttatg ttgtgtaaaa agatacagtc gattccacct
     5521 aagtgaatat ctgatttggg acacgaagaa actacacatc ccacctctgg ttcatccaca
     5581 gcctacccct gactgatgct tccaagacaa tacgcctttc cctctgatcc ctctaggacc
     5641 gcctagaggg ctacacttgg caaggcattt tatggtcttt tgaccacaca tgttctttcc
     5701 tctcccctcc ctcctatcca cagttcctaa catccgtgaa gtctctccta taaaccttaa
     5761 gagggacaga agcagtagac ccagggcttc ttcatctacc ttcaggtacg aagtctcatg
     5821 actacagtca gggttagaga gggttagaaa gcccttataa aagaggcaca ccctcaggga
     5881 gaggtaaaat aaagccagct ggccaacagc gggcagctaa aaaccattaa gcttaggtgt
     5941 gtgctgcact gatcaatggg tatgtataga agtgcatttc tattcgctca tcaatttaat
     6001 ccaggagtag cttcaattat taccactcac agaagtggga agacttccag gtattcaatg
     6061 agggaggtgg ggagaattct gctcaagtcc ttgctgtctg tttacaaagg ggagctcaga
     6121 atgccatagg tccattgtcg tcccccctcc ccctcccccc cccccaccgc agtagacaca
     6181 ggataggaag gagatgtgct ctcactgtac ccaacccctg atcagagaag aactgcccca
     6241 ctgcccatgc tgtgacaagc cctccccgct ctactgtcta cttgctcagg agtctggctg
     6301 ccctcaaaga gtatttccca tggctatctg ctcccttctc ttctcgcccg tgccaggaca
     6361 cctgagctgg tgtcagcgaa agctctggct gcccaccctc tggtttcagc tggcccctca
     6421 ggcccctttc ttcagtcagg tcaacaacca tgggcctacc aaacagaaga aaggtggctc
     6481 tttccctagg ccaaacctct cactgggcat gaggttccga gccctgctcc tactctgaca
     6541 aaagctgatt cctagtgaca cctgtgctgg ctttctcagg gcggggcctg cttgctcagt
     6601 tgcctctgaa aggccactgc ttcactagtg agggaagacc aaagtgtggt ttctttttct
     6661 tttctggagg aatgggcggc atcagggagg gaaggcctgg gaaagaggat ggtaaaattt
     6721 gttccaagat gtgtttcttt ttgaaatcct aatatgacca ccattcagca cagggcatga
     6781 tgttcgcgca ctgaaagaca aactgggctt ttctaccgaa gacacaaagg ctcggtcctg
     6841 taagcacttg tgactataaa gtcagccgct gcttaaattc acactcagcg tttatttttt
     6901 gtgtaactcc caccatggtt gtgagcaggt ctgcccatgc acaggccacc atgagaagcc
     6961 agacaactgt cagcattcac tggctgatgg aagccatatg cctgccaggc cgaagcaatg
     7021 gggtgtgatc tgcaggctcg tagctagcag gctaggcaat gcagtgaaca caagcggacc
     7081 atgcatcgtt cctgataagt gaataaaaca ctgtggccag acaatcagct tattcactta
     7141 tcaggaatcg actgttctac taattcactg gttttgtttt tcattctgtt gtagttcact
     7201 atttttgctg tgttctgttt ttttttcctc tcatgcttgg gcaaattcac tggagatatt
     7261 accttcatgt gaccatgaac cgtttctatc gagtgaaaat ggtatcttaa caaaatctat
     7321 gcacttgcta tcaggaacac aatactggat gtgtcttata tatattgaac tatatagtac
     7381 tcgatttctt aaataaagct taagaaagga tttgtgtgca aagtgaatgt gattctttct
     7441 caaagcagtg tctttaaggg gtattgttca tttaagtctt caatgatata ggatattttt
     7501 cattaaaatt atagcattgt ctttatgaat taatattcaa taaatggact ttggaaacaa
     7561 aaaaa
//
