LOCUS       NM_001406169            7814 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus CUGBP, Elav-like family member 1 (Celf1), transcript
            variant 10, mRNA.
ACCESSION   NM_001406169 XM_030247084
VERSION     NM_001406169.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7814)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 7814)
  AUTHORS   Siddam,A.D., Duot,M., Coomson,S.Y., Anand,D., Aryal,S.,
            Weatherbee,B.A.T., Audic,Y., Paillard,L. and Lachke,S.A.
  TITLE     High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens
            Identifies Downstream Networks Linked to Cataract Pathology
  JOURNAL   Cells 12 (7), 1070 (2023)
   PUBMED   37048143
  REMARK    GeneRIF: High-Throughput Transcriptomics of Celf1 Conditional
            Knockout Lens Identifies Downstream Networks Linked to Cataract
            Pathology.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7814)
  AUTHORS   Yu,T.X., Kalakonda,S., Liu,X., Han,N., Chung,H.K., Xiao,L.,
            Rao,J.N., He,T.C., Raufman,J.P. and Wang,J.Y.
  TITLE     Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains
            intestinal epithelial homeostasis and response to tissue injury
  JOURNAL   JCI Insight 7 (19), e156612 (2022)
   PUBMED   36214222
  REMARK    GeneRIF: Long noncoding RNA uc.230/CUG-binding protein 1 axis
            sustains intestinal epithelial homeostasis and response to tissue
            injury.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7814)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7814)
  AUTHORS   Chang,K.T., Wang,L.H., Lin,Y.M., Cheng,C.F. and Wang,G.S.
  TITLE     CELF1 promotes vascular endothelial growth factor degradation
            resulting in impaired microvasculature in heart failure
  JOURNAL   FASEB J 35 (5), e21512 (2021)
   PUBMED   33811692
  REMARK    GeneRIF: CELF1 promotes vascular endothelial growth factor
            degradation resulting in impaired microvasculature in heart
            failure.
REFERENCE   6  (bases 1 to 7814)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   7  (bases 1 to 7814)
  AUTHORS   Silver,A., Moody,J., Dunford,R., Clark,D., Ganz,S., Bulman,R.,
            Bouffler,S., Finnon,P., Meijne,E., Huiskamp,R. and Cox,R.
  TITLE     Molecular mapping of chromosome 2 deletions in murine
            radiation-induced AML localizes a putative tumor suppressor gene to
            a 1.0 cM region homologous to human chromosome segment 11p11-12
  JOURNAL   Genes Chromosomes Cancer 24 (2), 95-104 (1999)
   PUBMED   9885975
REFERENCE   8  (bases 1 to 7814)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   9  (bases 1 to 7814)
  AUTHORS   Neophytou,P.I., Muir,E.M. and Hutton,J.C.
  TITLE     A subtractive cloning approach to the identification of mRNAs
            specifically expressed in pancreatic beta-cells
  JOURNAL   Diabetes 45 (2), 127-133 (1996)
   PUBMED   8549854
REFERENCE   10 (bases 1 to 7814)
  AUTHORS   Alexander,B.J., Rasko,J.E., Morahan,G. and Cook,W.D.
  TITLE     Gene deletion explains both in vivo and in vitro generated
            chromosome 2 aberrations associated with murine myeloid leukemia
  JOURNAL   Leukemia 9 (12), 2009-2015 (1995)
   PUBMED   8609710
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672241.6.
            
            On May 10, 2022 this sequence version replaced XM_030247084.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1423139.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               AL672241.6         88539-88694
            157-308             AL672241.6         135718-135869
            309-496             AL672241.6         146633-146820
            497-579             AL672241.6         149059-149141
            580-628             AL672241.6         149515-149563
            629-763             AL672241.6         151264-151398
            764-843             AL672241.6         151864-151943
            844-1005            AL672241.6         152754-152915
            1006-1069           AL672241.6         154685-154748
            1070-1198           AL672241.6         156225-156353
            1199-1312           AL672241.6         157255-157368
            1313-1498           AL672241.6         158446-158631
            1499-1642           AL672241.6         160752-160895
            1643-1807           AL672241.6         161291-161455
            1808-7814           AL672241.6         161544-167550
FEATURES             Location/Qualifiers
     source          1..7814
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 50.44 cM"
     gene            1..7814
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="CUGBP, Elav-like family member 1"
                     /db_xref="GeneID:13046"
                     /db_xref="MGI:MGI:1342295"
     exon            1..156
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            157..308
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     CDS             238..1770
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="isoform 4 is encoded by transcript variant 10;
                     CUG-BP- and ETR-3-like factor 1; embryo deadenylation
                     element-binding protein homolog; CELF-1; EDEN-BP homolog;
                     brain protein F41; bruno-like protein 2; deadenylation
                     factor CUG-BP; RNA-binding protein BRUNOL-2; deadenylation
                     factor EDEN-BP; CUG triplet repeat RNA-binding protein 1;
                     50 kDa nuclear polyadenylated RNA-binding protein"
                     /codon_start=1
                     /product="CUGBP Elav-like family member 1 isoform 4"
                     /protein_id="NP_001393098.1"
                     /db_xref="GeneID:13046"
                     /db_xref="MGI:MGI:1342295"
                     /translation="MAAFKLDFLPEMMVDHCSLNSSPVSKKMNGTLDHPDQPDLDAIK
                     MFVGQVPRTWSEKDLRELFEQYGAVYEINILRDRSQNPPQSKGCCFVTFYTRKAALEA
                     QNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQ
                     IEECRILRGPDGLSRGCAFVTFTTRTMAQTAIKAMHQAQTMEGCSSPMVVKFADTQKD
                     KEQKRMAQQLQQQMQQISAASVWGNLAGLNTLGPQYLALLQQTASSGNLNTLSSLHPM
                     GGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSSPSSSSSNSVN
                     PIASLGALQTLAGATAGLNVGSLAGMAALNGGLGSSGLSNGTGSTMEALTQAYSGIQQ
                     YAAAALPTLYNQNLLTQQSIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGN
                     VVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSK
                     PY"
     exon            309..496
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            497..579
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            580..628
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            629..763
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            764..843
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1005
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1069
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1198
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1312
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1498
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1642
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1807
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..7814
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7795..7800
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="hexamer: ATTAAA"
     polyA_site      7814
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="major polyA site"
ORIGIN      
        1 gggtgttctg ctctggcggc agcggcagcg gcagaggcgg cggcggcggc gggacgcgga
       61 ggctcccccg ggattcggcc tcagcagcga ggcagcggcg gctgcggagg agcaaggcag
      121 cagctgaggc agcggcgggc tcaggtgcag ccgctggaag ctaaagctgt gtatatttgt
      181 ggatcagaca agtgcagcaa gttattatca ttggcttctg aaggggagag tgaggtgatg
      241 gctgcgttta agttggattt ccttccagaa atgatggtgg atcattgctc tttgaattcc
      301 agtcctgtct caaagaaaat gaacggcacc ctggaccacc cagaccaacc agatcttgat
      361 gctatcaaga tgtttgtggg ccaggttcca aggacctggt ctgagaaaga cttgagggag
      421 ctttttgagc agtatggtgc tgtctatgaa atcaacatcc taagggatag gagccaaaac
      481 cctcctcaga gcaaagggtg ctgttttgtt acattttaca cccgtaaagc tgcattagaa
      541 gctcagaatg ctctccataa catgaaggtc ctccctggga tgcatcaccc tatacagatg
      601 aagcctgctg acagtgaaaa gaacaatgct gtggaagaca ggaagctctt tattggtatg
      661 atttccaaga agtgtactga aaatgacatc cgagtcatgt tttcttcgtt tggacagatt
      721 gaagagtgcc ggatattgcg gggacctgat ggcttgagca gaggttgtgc atttgtgact
      781 tttactacaa gaaccatggc acagacagct atcaaagcaa tgcaccaagc acaaaccatg
      841 gagggttgct catccccaat ggtggtaaag tttgccgaca cccagaagga caaagaacag
      901 aagagaatgg cccagcagct ccagcagcag atgcagcaga tcagtgcagc gtctgtgtgg
      961 ggaaacctgg ctggtctgaa cacacttgga ccccagtact tagcactcct acagcagact
     1021 gcctcctctg ggaacctcaa caccctgagc agcctccacc caatgggagg gttaaatgca
     1081 atgcagctac agaatttggc tgcactagct gctgcagcta gtgcagctca gaacacacca
     1141 agtggtacca atgctctcac tacatccagc agtcccctca gcgtactcac cagttcagca
     1201 gggtcttcac cgagctccag cagcagtaat tctgtcaacc ccatagcctc acttggagcc
     1261 ctgcaaacat tggccggagc aacagctggc ctcaacgttg gctcattggc agggatggct
     1321 gctttgaatg gtggtctggg cagcagtggc ctttccaatg gcactgggag taccatggaa
     1381 gccctcaccc aggcgtattc tggtatccag caatatgctg ctgcagccct ccccactctg
     1441 tacaaccaga atttattgac acagcagagt attggtgctg ctggaagcca gaaggaaggt
     1501 ccagaaggag ccaacctgtt catctatcac ctgccccagg agtttggaga ccaggactta
     1561 ctgcagatgt ttatgccctt tgggaatgtc gtgtcggcca aggttttcat agacaagcag
     1621 acaaacctga gcaagtgctt tggttttgta agttatgaca atcctgtctc agctcaagct
     1681 gccatccagt ccatgaacgg ctttcaaatt ggaatgaaga ggcttaaagt gcagctcaaa
     1741 cgttcgaaga atgatagtaa gccctactga gtgctcccct ctgagactgg agtgagaaga
     1801 tcttctggca cagcttgccc tgaagactca gctactgcct tctgtgggag tgtcgcttcg
     1861 tacagaggac aagtttgtgc tttggtttcc agtgttttac tttggagttt aggtgccata
     1921 tcctgagggg ttttgttttg ttttgttttg ttttgtttct ttttcccttt atttaaagtt
     1981 tgctgtgttt gtaaccagtt tgttgagaag gaccaacacc agtccacctt gaggaagagg
     2041 gaaatgggtt taaaagataa ttagaacatg ccccaaacca tggaaagaga gggctgagca
     2101 gaacagaaag ttgatccccg aagtctctct ccctgtgtgg aaagagtgag aactaagtct
     2161 aatgaggtac ggggtgggtg agtgggtgag gtgtcttagc ttctagaccc cttagaactg
     2221 gctgctttct gtggaaatgc tgaatttatg ccacctattt ttctaatttt tgtcctggat
     2281 ttctgccctt ctttcctaaa agggggtaag caagtctcat gaaataatgc acttttcagt
     2341 tagcctgaaa tatgcaaata ggagggagat acccatgact aggcagccca gcccgacatt
     2401 cgtgttatat tgattgccct gcctggttgg tggctgttta ggggaagcag ccagagaggt
     2461 cattttcatt aattttaaca tgaagttaga atgtacccat ttccagtagt ctcttttgta
     2521 gaaagtatat ggaagttcat aacaccaagg aatgttgcct ccttctctgg ccacagtttt
     2581 ctcatgaggg gacataagac actcttaaca gcatctctag ccaacaaggg tgcagttcat
     2641 gggcagagca gtcaagaagc catctgatta agggaagaga gacctgcttc ttggtgtgcc
     2701 tgaatcaagg tcacttcaag ccactttgct atatttgagc agagcctagt attcaagaag
     2761 gttcagaagt gcatttctga ttccttaatg aaggtactcc aaaagctgtg ttcccataag
     2821 gtctggcagg cctctcctct agccccattt tctgtccttg aagacagaag aaagtatagg
     2881 acgtttacag gctccatatg gatttagtgt tcatttacct cagtattaac ccatgttcat
     2941 tttgtcatca tgcttacagt aagctccctg ctgcctttca tgggtcttaa ctccagcctt
     3001 tgccagtgtc ccacatagcc tctgggctct cctgctctaa gagaagctgt gggaatgtgc
     3061 atctgagcag aggtagccct ataaatatat gattagtagt cacagccagg gcctgggttc
     3121 ctgggtcatt ggaagcttaa acctcataag ttacaagtct tgactcctag cagcagagat
     3181 tagaaggggc taacctgctt taagtcagat agggactctc cttgtcatgc tgtccctgtg
     3241 gataacaaac agggattgac catcttgctg ttgtacagga agttgttagt ggtgtgttat
     3301 cccattgatg ctgggacagc tgttctctta tagtgataag ttgagtctgt tgtcctctta
     3361 aacatgaaac atacacttct taagctgaac cacgtaaact tgaattctgt gcactgggag
     3421 aaaagtgtcc tgtgtttcaa gataaaactg ttctaaaggc ttccagggta ttgatggaat
     3481 tttttaaaat aatgcaaaaa aaataaaaaa taaaaaactt taaaaggaaa aaaaagaaaa
     3541 aaatgctagg ttgggcaggc actgctcaga atcccaaccg gccggaacca agaatgttgt
     3601 ttctattttt atagaagttt tatacagctc cggggtggag aatatttatt acctaaatta
     3661 tatctctgga aaaggccagg attttgtaga atccagaatg tgattgttgt acacacaggg
     3721 tgctgtgtat gattgaaact actgactttc tgtgaccgtt tgcagcccag gtaacctgtc
     3781 caaggggaag gctaacatta atgctgtgaa ttggcagagg cgagagctgt gctccacagg
     3841 gagctgccag tgctgtgctc cctaaccttc tgttctgcct tcctcctcgg ccagaacatc
     3901 acgttctccc tgctcctctg gttccctcta gctctcccat ttcattgtcc acagatttgt
     3961 cctgtgctcc aggaccaaat gaaactttcc taatgatatt agaagcaaag gagtgacccc
     4021 acctttggaa cagaccccaa acttcatacc tacttgtgat ttctaaaagg agcacttgcc
     4081 ccagcagagc catggtcagc catggctggc tcagttagcc agctagccag ctggggagac
     4141 catgtacttc cattatcccg tttgcccagt gcattagcac agcactagca ctgtcctcga
     4201 gcacagttcc ctccccaggc caaagatggt tttgttgaag aagctgctcc cctataagtc
     4261 ttgatgtgaa agggctcagc ttagagtgga gactgaagtg acgtcttaag cagtccattt
     4321 ctgttgtgtg gaggtttcac ttacagtgtt ttctgctgta gttttgtttc gtggattata
     4381 tcatgccatt gatttgcctt cagtgcagcc caaccactat ctcctgggtt ccacaagagt
     4441 gcccagggcg tatgtggaac cttagggctt ggatttctgg gaacaagggt gggccatcct
     4501 aggattgagc aagaaactct ggccctctat ctaccctaag tagtctccct cccactctag
     4561 ttagcatctt ttgttgctga gaccctgctt gcccagagac tgtcttcatg tgttaggtgc
     4621 tttgcaggaa atccaagcct taggttcccc tctgtctctg gcagttggat gttctcttgg
     4681 tgtccttcat gtccttttga actttcccct gtgtccattg ttagcatgtg caaaagttct
     4741 tgtcatttcc cacccctgcc cttccccgtc tcctcatttc agggctgcat acagtgagtg
     4801 tcctgttctc tctctctgtt tggatgtatt gctctgtgta actcagtgga tctccctctt
     4861 tctggtttgt ttttttttct agattcctgc cgtttgttca tcgttgtgcc taaagcatgt
     4921 cgatgtggcg tcaagtacat cgtccaaatc cctgtctctt cagcttctct gatgcttgaa
     4981 ctctcacctt tgaccttgtg ttgacctttg atgctgatgt gtattttatt atgtttgttt
     5041 ctttctttgt tttttctttt ttctttcttt tttttttttc ccttttgtgc tgccaaattg
     5101 gttttgctag aacgactgct gaagggaaaa tatttaaact tgcatttgaa tataaaaaaa
     5161 aatctatttt tctagaactt cataagataa ccacttgatt ttgtgattcc aattctttgt
     5221 aactgtctca gagcagccct actagcacat gccgtgtggt gtttgtatcc ttgtgaacac
     5281 acagccagtc cgcttccagg ctttgttcct ctgtgtgctt agttttaaag acaactttga
     5341 aataaacaat gaaataaaag atgtcactaa aatctttgag gctcctgaac acattttgct
     5401 gacatagttt tggggcttga ggagaccgca tgttgttatt aatttttgtt tttctgagtt
     5461 ctcaactgca gaaaaatgtc tgaaatacac ccttaccccc attccctttt cactgaatgc
     5521 tgaggtttgg gccccagcta gccttttttc ttttcctttt gtggttcttc ctgaagcagc
     5581 cctgcaggga agccctaggg tccctcttcc cctcccctcc cctcggctca gccagctcac
     5641 acccgtgctt cttcctacag tctccacagc aaaatgtgat gctttcaact tttttgggtt
     5701 ttgtattctt ttgccttttt gttttgaatt tttcctttcc tactaagatt atgcccagaa
     5761 aaaacaagtt gtgcatgttt cctgctgttt cttcacacct tcgtatgtat caccttcacc
     5821 tctctgtttt ctatagtttg tgcaaaaact gactgattta aaggggtttc aaagaagatg
     5881 ttttaaattg ttatggggtt gatttttttt ctcaagattg tatcgtttta ttttgaagtg
     5941 gcaactttct cctctattgc ccttagagtg tttgcctgtg cacttagact gtcactcttt
     6001 gtggtggcct ccaggtctca gtgggggatc caggaggctg gctgctctgc tcagggagta
     6061 cagggggcca gaggcagaag cagaaccaaa ggtggctgtg ggtaggcagg atgcttaggg
     6121 catcaaggct agatcacgga gggagggagg gcaggcgggc agtacttctg attacccaga
     6181 ggaggccatc ggtgcactga gtggcaatat acctgcctgc ctgcgctttc cctaggtgac
     6241 aagcacaata aatactacag tcttcacact gtttacagct ctgggcacca accaccccgc
     6301 actggctctt cactatggct ctgctcttac ttagctaata gagttggggt aagggcaaga
     6361 aactgttttt aaattgggtg aagagccaga tagctactgt tcccgggtgc caggccagcc
     6421 agttctttgg tttcctaagg gaaacttacc ctcttctctt gtagcaccat ccagcctcag
     6481 ggtcttgggg acttggaaga atgtgaatag aggaggagag gctagaggaa atgagtagac
     6541 agggatggat ctgtgaagag cagaggctgc agggaggatt tttgacagat cccactgaga
     6601 cttaagcact ggtgggaggg aaagtggaag caaggttgtc caggaaaggg tggcaaggtg
     6661 cagcaaagga tgggggtggg gagagaagca cggtctggca tcatccactc tctgcctggt
     6721 gttgaaggaa ctccagcaca gtttctgctc tgggacccct acaggttgcc caatatatta
     6781 tgcttgaggc caccttacta ggaagaaatg gcagccaagt gggggactta agtatgctgc
     6841 ttaaggtcct ggaaggggtg gtaggatgcc agcgcctagc atgagagagc ctgctgtgtg
     6901 cccacagtct gactgcacag agcgcctctg tcggcaggag gtgctgcggt ccccttcctg
     6961 tgtactgaga agctgggctt gccaatatag tttgctttcg attccaagag gagctctggg
     7021 aaaacctgtg gataaaacca aatgccaaat gttggacatt gtttcctttt ccttttctct
     7081 ctgattgttt taattgttcc gtagtggttt taatggattt gagaccctgg agcggcagct
     7141 gcctttctga tttccagctg ctttttgtga ataatttaaa aagaaaaaaa aaagaaactt
     7201 tacattttgg agacaaacct gtgtgagttt tttattggta caaacgttgt atttaacact
     7261 aggggttttg tacagttttt tgccttttct actagaaaac aatgtaaagt gatttcacaa
     7321 tgtgaagaga aaaaaattgc cactatgacc aaacgcacag tctgttctgc agcaacaacg
     7381 ggattcaatc aactcaaagt cgtgattcag ccgtagaaat gcttttcttg accttgtttg
     7441 agctttcctt ttttcctgtt tgatttataa aagatgtctt ttgtgtgtga acttgtgttg
     7501 tactctgtag aaaattatgg attttgcttt aatggttttt aaaaaaaaaa aagggcaaga
     7561 agagcccgtg tcgcttttct tacctaatca cagtttgtgt agtggattaa aaaaagaaaa
     7621 agttgttaaa agtttggagc aagggagtat gtgtttaaaa ggactctcct tcctttttgt
     7681 gtgtgtttcc ttttgtccca atggggaacc taaatctgtt ttaattgcac agacacacag
     7741 acaaaaagtc attttgtatc tgccaagtgt ggtaccttcc tttgtttatt tgctattaaa
     7801 ctgtttgaga agaa
//
