LOCUS       NM_001406168            4751 bp    mRNA    linear   ROD 02-JUL-2024
DEFINITION  Mus musculus CUGBP, Elav-like family member 1 (Celf1), transcript
            variant 9, mRNA.
ACCESSION   NM_001406168 XM_030247083
VERSION     NM_001406168.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4751)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4751)
  AUTHORS   Siddam,A.D., Duot,M., Coomson,S.Y., Anand,D., Aryal,S.,
            Weatherbee,B.A.T., Audic,Y., Paillard,L. and Lachke,S.A.
  TITLE     High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens
            Identifies Downstream Networks Linked to Cataract Pathology
  JOURNAL   Cells 12 (7), 1070 (2023)
   PUBMED   37048143
  REMARK    GeneRIF: High-Throughput Transcriptomics of Celf1 Conditional
            Knockout Lens Identifies Downstream Networks Linked to Cataract
            Pathology.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4751)
  AUTHORS   Yu,T.X., Kalakonda,S., Liu,X., Han,N., Chung,H.K., Xiao,L.,
            Rao,J.N., He,T.C., Raufman,J.P. and Wang,J.Y.
  TITLE     Long noncoding RNA uc.230/CUG-binding protein 1 axis sustains
            intestinal epithelial homeostasis and response to tissue injury
  JOURNAL   JCI Insight 7 (19), e156612 (2022)
   PUBMED   36214222
  REMARK    GeneRIF: Long noncoding RNA uc.230/CUG-binding protein 1 axis
            sustains intestinal epithelial homeostasis and response to tissue
            injury.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4751)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4751)
  AUTHORS   Chang,K.T., Wang,L.H., Lin,Y.M., Cheng,C.F. and Wang,G.S.
  TITLE     CELF1 promotes vascular endothelial growth factor degradation
            resulting in impaired microvasculature in heart failure
  JOURNAL   FASEB J 35 (5), e21512 (2021)
   PUBMED   33811692
  REMARK    GeneRIF: CELF1 promotes vascular endothelial growth factor
            degradation resulting in impaired microvasculature in heart
            failure.
REFERENCE   6  (bases 1 to 4751)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   7  (bases 1 to 4751)
  AUTHORS   Silver,A., Moody,J., Dunford,R., Clark,D., Ganz,S., Bulman,R.,
            Bouffler,S., Finnon,P., Meijne,E., Huiskamp,R. and Cox,R.
  TITLE     Molecular mapping of chromosome 2 deletions in murine
            radiation-induced AML localizes a putative tumor suppressor gene to
            a 1.0 cM region homologous to human chromosome segment 11p11-12
  JOURNAL   Genes Chromosomes Cancer 24 (2), 95-104 (1999)
   PUBMED   9885975
REFERENCE   8  (bases 1 to 4751)
  AUTHORS   Ko,M.S., Threat,T.A., Wang,X., Horton,J.H., Cui,Y., Wang,X.,
            Pryor,E., Paris,J., Wells-Smith,J., Kitchen,J.R., Rowe,L.B.,
            Eppig,J., Satoh,T., Brant,L., Fujiwara,H., Yotsumoto,S. and
            Nakashima,H.
  TITLE     Genome-wide mapping of unselected transcripts from extraembryonic
            tissue of 7.5-day mouse embryos reveals enrichment in the t-complex
            and under-representation on the X chromosome
  JOURNAL   Hum Mol Genet 7 (12), 1967-1978 (1998)
   PUBMED   9811942
REFERENCE   9  (bases 1 to 4751)
  AUTHORS   Neophytou,P.I., Muir,E.M. and Hutton,J.C.
  TITLE     A subtractive cloning approach to the identification of mRNAs
            specifically expressed in pancreatic beta-cells
  JOURNAL   Diabetes 45 (2), 127-133 (1996)
   PUBMED   8549854
REFERENCE   10 (bases 1 to 4751)
  AUTHORS   Alexander,B.J., Rasko,J.E., Morahan,G. and Cook,W.D.
  TITLE     Gene deletion explains both in vivo and in vitro generated
            chromosome 2 aberrations associated with murine myeloid leukemia
  JOURNAL   Leukemia 9 (12), 2009-2015 (1995)
   PUBMED   8609710
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL672241.6.
            
            On May 10, 2022 this sequence version replaced XM_030247083.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363660.3781.1,
                                           SRR17784649.1124785.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-156               AL672241.6         88539-88694
            157-308             AL672241.6         135718-135869
            309-496             AL672241.6         146633-146820
            497-579             AL672241.6         149059-149141
            580-628             AL672241.6         149515-149563
            629-763             AL672241.6         151264-151398
            764-843             AL672241.6         151864-151943
            844-1005            AL672241.6         152754-152915
            1006-1081           AL672241.6         154673-154748
            1082-1210           AL672241.6         156225-156353
            1211-1324           AL672241.6         157255-157368
            1325-1510           AL672241.6         158446-158631
            1511-1654           AL672241.6         160752-160895
            1655-1819           AL672241.6         161291-161455
            1820-4751           AL672241.6         164619-167550
FEATURES             Location/Qualifiers
     source          1..4751
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 50.44 cM"
     gene            1..4751
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="CUGBP, Elav-like family member 1"
                     /db_xref="GeneID:13046"
                     /db_xref="MGI:MGI:1342295"
     exon            1..156
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            157..308
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            309..496
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            497..579
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            580..628
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            629..763
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            764..843
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            844..1005
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1081
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1082..1210
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1324
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1510
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1654
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1819
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..4751
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4732..4737
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="hexamer: ATTAAA"
     polyA_site      4751
                     /gene="Celf1"
                     /gene_synonym="1600010O03Rik; Brunol2; CUG-BP; CUG-BP1;
                     CUGBP; Cugbp1; D2Wsu101e; HNAB50; NAB50"
                     /note="major polyA site"
ORIGIN      
        1 gggtgttctg ctctggcggc agcggcagcg gcagaggcgg cggcggcggc gggacgcgga
       61 ggctcccccg ggattcggcc tcagcagcga ggcagcggcg gctgcggagg agcaaggcag
      121 cagctgaggc agcggcgggc tcaggtgcag ccgctggaag ctaaagctgt gtatatttgt
      181 ggatcagaca agtgcagcaa gttattatca ttggcttctg aaggggagag tgaggtgatg
      241 gctgcgttta agttggattt ccttccagaa atgatggtgg atcattgctc tttgaattcc
      301 agtcctgtct caaagaaaat gaacggcacc ctggaccacc cagaccaacc agatcttgat
      361 gctatcaaga tgtttgtggg ccaggttcca aggacctggt ctgagaaaga cttgagggag
      421 ctttttgagc agtatggtgc tgtctatgaa atcaacatcc taagggatag gagccaaaac
      481 cctcctcaga gcaaagggtg ctgttttgtt acattttaca cccgtaaagc tgcattagaa
      541 gctcagaatg ctctccataa catgaaggtc ctccctggga tgcatcaccc tatacagatg
      601 aagcctgctg acagtgaaaa gaacaatgct gtggaagaca ggaagctctt tattggtatg
      661 atttccaaga agtgtactga aaatgacatc cgagtcatgt tttcttcgtt tggacagatt
      721 gaagagtgcc ggatattgcg gggacctgat ggcttgagca gaggttgtgc atttgtgact
      781 tttactacaa gaaccatggc acagacagct atcaaagcaa tgcaccaagc acaaaccatg
      841 gagggttgct catccccaat ggtggtaaag tttgccgaca cccagaagga caaagaacag
      901 aagagaatgg cccagcagct ccagcagcag atgcagcaga tcagtgcagc gtctgtgtgg
      961 ggaaacctgg ctggtctgaa cacacttgga ccccagtact tagcacttta tttgcagctc
     1021 ctacagcaga ctgcctcctc tgggaacctc aacaccctga gcagcctcca cccaatggga
     1081 gggttaaatg caatgcagct acagaatttg gctgcactag ctgctgcagc tagtgcagct
     1141 cagaacacac caagtggtac caatgctctc actacatcca gcagtcccct cagcgtactc
     1201 accagttcag cagggtcttc accgagctcc agcagcagta attctgtcaa ccccatagcc
     1261 tcacttggag ccctgcaaac attggccgga gcaacagctg gcctcaacgt tggctcattg
     1321 gcagggatgg ctgctttgaa tggtggtctg ggcagcagtg gcctttccaa tggcactggg
     1381 agtaccatgg aagccctcac ccaggcgtat tctggtatcc agcaatatgc tgctgcagcc
     1441 ctccccactc tgtacaacca gaatttattg acacagcaga gtattggtgc tgctggaagc
     1501 cagaaggaag gtccagaagg agccaacctg ttcatctatc acctgcccca ggagtttgga
     1561 gaccaggact tactgcagat gtttatgccc tttgggaatg tcgtgtcggc caaggttttc
     1621 atagacaagc agacaaacct gagcaagtgc tttggttttg taagttatga caatcctgtc
     1681 tcagctcaag ctgccatcca gtccatgaac ggctttcaaa ttggaatgaa gaggcttaaa
     1741 gtgcagctca aacgttcgaa gaatgatagt aagccctact gagtgctccc ctctgagact
     1801 ggagtgagaa gatcttctga ttcctgccgt ttgttcatcg ttgtgcctaa agcatgtcga
     1861 tgtggcgtca agtacatcgt ccaaatccct gtctcttcag cttctctgat gcttgaactc
     1921 tcacctttga ccttgtgttg acctttgatg ctgatgtgta ttttattatg tttgtttctt
     1981 tctttgtttt ttcttttttc tttctttttt ttttttccct tttgtgctgc caaattggtt
     2041 ttgctagaac gactgctgaa gggaaaatat ttaaacttgc atttgaatat aaaaaaaaat
     2101 ctatttttct agaacttcat aagataacca cttgattttg tgattccaat tctttgtaac
     2161 tgtctcagag cagccctact agcacatgcc gtgtggtgtt tgtatccttg tgaacacaca
     2221 gccagtccgc ttccaggctt tgttcctctg tgtgcttagt tttaaagaca actttgaaat
     2281 aaacaatgaa ataaaagatg tcactaaaat ctttgaggct cctgaacaca ttttgctgac
     2341 atagttttgg ggcttgagga gaccgcatgt tgttattaat ttttgttttt ctgagttctc
     2401 aactgcagaa aaatgtctga aatacaccct tacccccatt cccttttcac tgaatgctga
     2461 ggtttgggcc ccagctagcc ttttttcttt tccttttgtg gttcttcctg aagcagccct
     2521 gcagggaagc cctagggtcc ctcttcccct cccctcccct cggctcagcc agctcacacc
     2581 cgtgcttctt cctacagtct ccacagcaaa atgtgatgct ttcaactttt ttgggttttg
     2641 tattcttttg cctttttgtt ttgaattttt cctttcctac taagattatg cccagaaaaa
     2701 acaagttgtg catgtttcct gctgtttctt cacaccttcg tatgtatcac cttcacctct
     2761 ctgttttcta tagtttgtgc aaaaactgac tgatttaaag gggtttcaaa gaagatgttt
     2821 taaattgtta tggggttgat tttttttctc aagattgtat cgttttattt tgaagtggca
     2881 actttctcct ctattgccct tagagtgttt gcctgtgcac ttagactgtc actctttgtg
     2941 gtggcctcca ggtctcagtg ggggatccag gaggctggct gctctgctca gggagtacag
     3001 ggggccagag gcagaagcag aaccaaaggt ggctgtgggt aggcaggatg cttagggcat
     3061 caaggctaga tcacggaggg agggagggca ggcgggcagt acttctgatt acccagagga
     3121 ggccatcggt gcactgagtg gcaatatacc tgcctgcctg cgctttccct aggtgacaag
     3181 cacaataaat actacagtct tcacactgtt tacagctctg ggcaccaacc accccgcact
     3241 ggctcttcac tatggctctg ctcttactta gctaatagag ttggggtaag ggcaagaaac
     3301 tgtttttaaa ttgggtgaag agccagatag ctactgttcc cgggtgccag gccagccagt
     3361 tctttggttt cctaagggaa acttaccctc ttctcttgta gcaccatcca gcctcagggt
     3421 cttggggact tggaagaatg tgaatagagg aggagaggct agaggaaatg agtagacagg
     3481 gatggatctg tgaagagcag aggctgcagg gaggattttt gacagatccc actgagactt
     3541 aagcactggt gggagggaaa gtggaagcaa ggttgtccag gaaagggtgg caaggtgcag
     3601 caaaggatgg gggtggggag agaagcacgg tctggcatca tccactctct gcctggtgtt
     3661 gaaggaactc cagcacagtt tctgctctgg gacccctaca ggttgcccaa tatattatgc
     3721 ttgaggccac cttactagga agaaatggca gccaagtggg ggacttaagt atgctgctta
     3781 aggtcctgga aggggtggta ggatgccagc gcctagcatg agagagcctg ctgtgtgccc
     3841 acagtctgac tgcacagagc gcctctgtcg gcaggaggtg ctgcggtccc cttcctgtgt
     3901 actgagaagc tgggcttgcc aatatagttt gctttcgatt ccaagaggag ctctgggaaa
     3961 acctgtggat aaaaccaaat gccaaatgtt ggacattgtt tccttttcct tttctctctg
     4021 attgttttaa ttgttccgta gtggttttaa tggatttgag accctggagc ggcagctgcc
     4081 tttctgattt ccagctgctt tttgtgaata atttaaaaag aaaaaaaaaa gaaactttac
     4141 attttggaga caaacctgtg tgagtttttt attggtacaa acgttgtatt taacactagg
     4201 ggttttgtac agttttttgc cttttctact agaaaacaat gtaaagtgat ttcacaatgt
     4261 gaagagaaaa aaattgccac tatgaccaaa cgcacagtct gttctgcagc aacaacggga
     4321 ttcaatcaac tcaaagtcgt gattcagccg tagaaatgct tttcttgacc ttgtttgagc
     4381 tttccttttt tcctgtttga tttataaaag atgtcttttg tgtgtgaact tgtgttgtac
     4441 tctgtagaaa attatggatt ttgctttaat ggtttttaaa aaaaaaaaag ggcaagaaga
     4501 gcccgtgtcg cttttcttac ctaatcacag tttgtgtagt ggattaaaaa aagaaaaagt
     4561 tgttaaaagt ttggagcaag ggagtatgtg tttaaaagga ctctccttcc tttttgtgtg
     4621 tgtttccttt tgtcccaatg gggaacctaa atctgtttta attgcacaga cacacagaca
     4681 aaaagtcatt ttgtatctgc caagtgtggt accttccttt gtttatttgc tattaaactg
     4741 tttgagaaga a
//
