LOCUS       NM_001126318             958 bp    mRNA    linear   ROD 17-DEC-2024
DEFINITION  Mus musculus chymotrypsin-like elastase family, member 3A (Cela3a),
            mRNA.
ACCESSION   NM_001126318 XR_034091
VERSION     NM_001126318.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Martinez-Ramirez,A.S., Borders,T.L., Paul,L., Schipma,M., Wang,X.,
            Korobova,F., Wright,C.V. and Sosa-Pineda,B.
  TITLE     Specific Temporal Requirement of Prox1 Activity During Pancreatic
            Acinar Cell Development
  JOURNAL   Gastro Hep Adv 1 (5), 807-823 (2022)
   PUBMED   37829188
REFERENCE   2  (bases 1 to 958)
  AUTHORS   Hale,M.A., Swift,G.H., Hoang,C.Q., Deering,T.G., Masui,T.,
            Lee,Y.K., Xue,J. and MacDonald,R.J.
  TITLE     The nuclear hormone receptor family member NR5A2 controls aspects
            of multipotent progenitor cell formation and acinar differentiation
            during pancreatic organogenesis
  JOURNAL   Development 141 (16), 3123-3133 (2014)
   PUBMED   25063451
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645468.11.
            
            On May 7, 2008 this sequence version replaced XR_034091.1.
            
            Sequence Note: This RefSeq record was created from genomic sequence
            data because no single transcript from the reference strain was
            available for the full length of the gene. The extent of this
            transcript is supported by alignment of partial transcripts and
            paralogous data.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMN00849377, SAMN00849389
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AL645468.11        156231-156302       c
            73-158              AL645468.11        154636-154721       c
            159-256             AL645468.11        152347-152444       c
            257-391             AL645468.11        152092-152226       c
            392-528             AL645468.11        150896-151032       c
            529-658             AL645468.11        150311-150440       c
            659-866             AL645468.11        148986-149193       c
            867-958             AL645468.11        148065-148156       c
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 69.88 cM"
     gene            1..958
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /note="chymotrypsin-like elastase family, member 3A"
                     /db_xref="GeneID:242711"
                     /db_xref="MGI:MGI:3651647"
     exon            1..72
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..884
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /codon_start=1
                     /product="chymotrypsin-like elastase family, member 3A
                     precursor"
                     /protein_id="NP_001119790.1"
                     /db_xref="CCDS:CCDS51332.1"
                     /db_xref="GeneID:242711"
                     /db_xref="MGI:MGI:3651647"
                     /translation="MLRLLSSLLLVALASGCGQPSHNPSSRVVNGEEAVPHSWPWQVS
                     LQYEMGGSFHHTCGGSLITPDWVLTAGHCIMPYLNYRVVLGEHEHGVEEGSEQVIPIN
                     AGELFVHPKWNSECVNCGNNIALVKLSRSAQLGDAVQLACLPPAGEILPNGAPCYISG
                     WGRLSTNGPLPTKLQQALLPVVDYEHCSRWDWWGHYVKRTMVCAGGYIQAHSLSSDTH
                     QPRLLSPLQGDSGGPLNCPADNGTWQVHGIASFVSPSGCNTLKKPTMFTRVSAFIDWI
                     EETIANN"
     exon            73..158
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     exon            159..256
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     exon            257..391
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     exon            392..528
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     exon            529..658
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     exon            659..866
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     exon            867..958
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /inference="alignment:Splign:2.1.0"
     regulatory      929..934
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /note="hexamer: AATAAA"
     polyA_site      953
                     /gene="Cela3a"
                     /gene_synonym="Gm13011"
                     /note="major polyA site"
ORIGIN      
        1 tccacatctt tcttatcacc ctgaagctca ccatgctccg actgctgagt tccctcctgc
       61 ttgtggccct tgcctcaggc tgtggacagc cttcccacaa cccctccagc cgagttgtca
      121 atggcgagga agctgttccc cacagctggc cctggcaggt ctcccttcag tatgagatgg
      181 gtgggagctt ccaccatacc tgtggtggct ccctcattac ccctgactgg gttctgactg
      241 cgggccactg catcatgcct tatctcaact accgggtggt acttggggag catgaacatg
      301 gtgtggagga gggctcagag caggtgatcc ccatcaatgc tggagaactc tttgtgcacc
      361 ccaagtggaa ctccgaatgt gtgaactgtg gcaataacat cgctctggtc aagctctcaa
      421 gaagtgccca gctgggagat gcagtccagc ttgcctgcct ccctcctgct ggtgaaatcc
      481 tacccaacgg agcaccctgt tacatcagcg gctggggccg gctctctacc aatggacctc
      541 tgccaaccaa gctgcagcag gccttgctgc ctgtggtgga ctatgaacac tgctccaggt
      601 gggactggtg gggccactat gtgaagagga ccatggtgtg cgccggcggc tacatccaag
      661 cccactcctt atcttcagac acacatcagc cccgactctt gtctccattg cagggtgact
      721 ctggaggacc cctcaactgt cccgctgaca atggcacctg gcaggtccat ggtatagcca
      781 gcttcgtgtc cccctcgggc tgcaacaccc tgaagaagcc cacaatgttc acccgtgtct
      841 cagccttcat tgactggatt gaggagacca ttgccaacaa ctagatccaa ggttcggctg
      901 gcagagagga cccccaggtc ctctaaagaa taaagacctt ttgaaagtcc caagttga
//
