LOCUS       NM_028480               3248 bp    mRNA    linear   ROD 08-DEC-2024
DEFINITION  Mus musculus CEA cell adhesion molecule 5 (Ceacam5), mRNA.
ACCESSION   NM_028480 XM_145406 XM_900489 XM_985186 XM_990318
VERSION     NM_028480.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3248)
  AUTHORS   Luo,Y., Zhang,Z., Ren,J., Dou,C., Wen,J., Yang,Y., Li,X., Yan,Z.
            and Han,Y.
  TITLE     SARS-Cov-2 spike induces intestinal barrier dysfunction through the
            interaction between CEACAM5 and Galectin-9
  JOURNAL   Front Immunol 15, 1303356 (2024)
   PUBMED   38686388
  REMARK    GeneRIF: SARS-Cov-2 spike induces intestinal barrier dysfunction
            through the interaction between CEACAM5 and Galectin-9.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3248)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 3248)
  AUTHORS   Abdul-Wahid,A., Huang,E.H., Cydzik,M., Bolewska-Pedyczak,E. and
            Gariepy,J.
  TITLE     The carcinoembryonic antigen IgV-like N domain plays a critical
            role in the implantation of metastatic tumor cells
  JOURNAL   Mol Oncol 8 (2), 337-350 (2014)
   PUBMED   24388361
  REMARK    GeneRIF: a new mechanistic insight into how the CEA IgV-like N
            domain participates in cellular events that can have a macroscopic
            impact in terms of cancer progression and metastasis.
REFERENCE   4  (bases 1 to 3248)
  AUTHORS   McLellan,A.S., Fischer,B., Dveksler,G., Hori,T., Wynne,F., Ball,M.,
            Okumura,K., Moore,T. and Zimmermann,W.
  TITLE     Structure and evolution of the mouse pregnancy-specific
            glycoprotein (Psg) gene locus
  JOURNAL   BMC Genomics 6, 4 (2005)
   PUBMED   15647114
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK145976.1.
            
            On Apr 6, 2007 this sequence version replaced NM_028480.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK145976.1, AK146102.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3248              AK145976.1         2-3249
FEATURES             Location/Qualifiers
     source          1..3248
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.15 cM"
     gene            1..3248
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /note="CEA cell adhesion molecule 5"
                     /db_xref="GeneID:73250"
                     /db_xref="MGI:MGI:1920500"
     exon            1..259
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     CDS             196..3039
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /note="pregnancy-specific glycoprotein 30;
                     carcinoembryonic antigen-related cell adhesion molecule 5;
                     cell adhesion molecule CEACAM5"
                     /codon_start=1
                     /product="cell adhesion molecule CEACAM5 precursor"
                     /protein_id="NP_082756.1"
                     /db_xref="CCDS:CCDS20863.1"
                     /db_xref="GeneID:73250"
                     /db_xref="MGI:MGI:1920500"
                     /translation="MEASSVLPCKWCTHLQGLLLTASFLTCCHLPTTAQITIELEPPQ
                     VIEGENVLIRVNNLTENLITLAWFRGMRIKSPQIGQYTPATKVTVLGPGHSGRETLYS
                     NGSLQIYNVTQEDIGFYSLRIINKHAEIVSITSIYLNVYSSLWTCEHPSPHAKLTIES
                     VPPGISEGGSVLLLVKNLPQNLLSLFWYKGVIAVKKFEIARHIKATNSSVPGPAHTGR
                     ETVFSNGSLLLQEVMQSDTGFYTLRTMSTDLKDEVAHVQLYMDTYLLTCYHPLQVKIE
                     SLPQNVAVGKTVLLLVHNLPEDFQAFFWYKSAYRRDTYKIAEYKRAMDATILGSAYSS
                     REFIYNNGSMLIIDVTEDDAGYFLLEILREDLKIEKAYIQLHVNSFVSNSKDSASTAR
                     LSIESVPPSIVEGGSVLLLVHNLPKNLQSLFWYKGMIAEKKSELIQHIIATSSSLPGP
                     AHSGRETVYNNGSLLLQRVMQNDTQFYTLQTMDTDLKYEVAHVQLQLDTSLSTWYHPL
                     QVKIESLPRNVAVGKSVLFLVHNFPEVFRAFSWYKPAYKSHTSKIVEYHRFTDSATVG
                     AAYRGIEVIFTNGSMVMIDVTEDDAGFYMLEILREDFKVEKAYVQLHVNSFVPNSKVS
                     VSTARLSIESVPPSIVGGESVLLLVHNLPKNLQSLFWYKGVIAEEKSELIQHIIATSS
                     SLPGPAHSGRETVYSNGSLLLQRVMQNDTGFYTLLTMSTDLKDEIAHVQLQLDTSTCC
                     SLLTSDQLIIVPVPRNIAVGKSVLLLVCNVPKDVQTIFWYKSVYRTDIFKIAEYSRSM
                     ESTIWGLAHSGKEMVYTNGSLLIQNVTEHDAGLYMLEILHKDYKLERAHVQVHVNNPV
                     SWPFVRVTDTTVRVQSSVVFTCFSADPGVSIRWLFNKQSLQLTERMTLSPSKCQLSID
                     PVWREDAGKYQCEVSNPVSSKSSLPVRLAVIEE"
     exon            260..619
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            620..979
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1330
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1690
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..2041
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2401
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            2402..2755
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
     exon            2756..3248
                     /gene="Ceacam5"
                     /gene_synonym="1600029H12Rik; Psg30"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggacagtac tgagagtgga aggaatagat cagtgcctta ggcatagacc ccactaccca
       61 cagcccattg gattctggaa agtggtcctt tcttgggaga cactcagcta agaagaagga
      121 catacagaag aacttgggtg ctgtgctaga gctaaagctt ttttccagag ggaggagagc
      181 acagatagaa gagagatgga agcatcctct gtccttccat gcaagtggtg tacccacttg
      241 caggggcttc tgctcacagc ctccttttta acctgctgtc acctgcctac cactgcacaa
      301 ataaccattg aattagagcc accccaagtg attgaaggag aaaatgttct catacgtgtc
      361 aacaatttga cagagaatct tataacctta gcctggttca gaggaatgag gattaagagc
      421 cctcaaattg gacaatatac accggccact aaagttactg tgctgggtcc tggtcacagt
      481 ggtagagaaa ctttgtacag caatggatcc ctgcagatct acaatgtcac ccaggaggac
      541 ataggattct acagcctacg aatcataaat aaacatgcag aaattgtgtc aataacatcc
      601 atatacctca acgtgtactc atctctatgg acatgtgagc acccttctcc ccatgccaag
      661 ctcaccattg aatcagtgcc acccggcatt tctgaagggg gaagtgttct tctactggtt
      721 aaaaatctcc cccaaaatct tctatccctt ttctggtaca aaggagttat tgcagtgaag
      781 aaatttgaga ttgccagaca cataaaagcc acaaattcaa gtgttccagg gcctgcacac
      841 actggtcgtg agacagtatt cagcaatgga tcccttctgc tacaggaagt tatgcagagt
      901 gatactggat tctatactct acgaactatg agtacagatc tgaaagatga agtagcacat
      961 gtgcagctgt acatggacac ctatcttttg acttgttatc accctttgca agtcaagatc
     1021 gaatcacttc ctcagaatgt tgctgtaggg aaaactgttc ttctcttagt tcataatttg
     1081 cctgaagact ttcaagcatt tttctggtac aaatcagcat atagaagaga tacatacaaa
     1141 attgcagaat acaagagagc catggatgcc accattttgg ggagtgcata cagttcaaga
     1201 gagtttatat acaacaacgg atccatgcta ataattgatg tcactgagga tgatgcagga
     1261 tatttcctgc tagaaatttt aagagaagac ttaaagattg aaaaagccta cattcaactc
     1321 catgtaaata gctttgtttc aaactccaag gactctgcct ccactgcaag gctcagtata
     1381 gaatcagtgc caccgagcat tgttgaaggg ggaagtgttc ttttactggt tcacaatctc
     1441 ccaaaaaatc ttcaatccct tttctggtac aaagggatga ttgcagagaa gaaatctgag
     1501 ctcatacaac acataatagc cacaagttca agcttgccag ggcctgcaca cagtggtcga
     1561 gaaacagtat acaacaatgg atccctgctg ctccagaggg tcatgcaaaa tgatactcaa
     1621 ttttatactc tacaaactat ggatacagat ctgaaatatg aagtagcaca tgttcaactc
     1681 cagctggaca cttccctttc tacttggtat caccctttgc aagtcaagat cgaatcactt
     1741 cctcggaatg ttgctgtagg aaaaagtgtt ctttttctgg ttcataattt tccagaagtc
     1801 tttcgagcat tttcctggta taaaccagcg tataagtcac atacatccaa aattgtagaa
     1861 taccacagat tcacggattc tgccaccgtg ggggctgcat acagaggaat agaggtgata
     1921 ttcaccaacg gatccatggt gatgattgat gtcactgagg atgatgcagg gttttacatg
     1981 ctagaaattt taagagaaga cttcaaagtt gaaaaagcct atgttcaact ccatgtaaat
     2041 agctttgttc caaactcaaa ggtctctgtc tccactgcaa ggctcagtat agaatcagtg
     2101 ccccccagca ttgttggagg ggaaagtgtt cttctactgg ttcacaatct tccaaaaaat
     2161 cttcaatctc ttttctggta caaaggcgtg attgccgagg agaaatctga gctcatccaa
     2221 cacataatag ccacaagttc aagcttgcca gggcctgcac acagtggtcg agaaacagtg
     2281 tacagcaatg gatccctgct gctccagagg gtcatgcaga atgatactgg attctatact
     2341 ctactaacta tgagtacaga tctgaaagat gaaatagcac atgtgcaact ccagctggac
     2401 acctctactt gctgtagcct tctcacctct gaccaactca taattgtacc agtgcctcgg
     2461 aatattgctg tagggaaaag tgttcttctc cttgtttgca atgtgccaaa ggatgttcag
     2521 acaattttct ggtacaaatc ggtgtatcga acagatattt ttaaaattgc agaatatagc
     2581 agatccatgg aatctactat ctgggggctt gcacacagtg gaaaagagat ggtgtacact
     2641 aatggatccc ttctgatcca gaatgtcact gagcatgatg caggattgta catgttagaa
     2701 attttacata aggactacaa acttgagaga gcacatgtgc aagtccatgt aaataaccct
     2761 gtttcatggc cttttgtgcg agtgactgac accacagtca gagtacagag ctcagtagtc
     2821 ttcacttgct tctcagctga ccctggtgtc tccatccgtt ggctcttcaa taagcagagt
     2881 ctgcagctca cagagagaat gacactttcc ccatcaaagt gccaactcag catagatcct
     2941 gtctggaggg aggatgctgg aaagtatcaa tgtgaggtct ccaacccagt cagttcaaag
     3001 tccagtctcc cagtccgtct ggctgtgata gaagagtgac ctctctcctc tcatcctaca
     3061 gcagagtgga gtcatttcct tattgatggg gtgcaaaatg gagatgagtc aagtggtaaa
     3121 agttgtcagt taccactcaa gtactgcctt cattgtaact catacctgta gtcctgacat
     3181 aatcatgtgt ggaaggacag gccatgattt aatgtgaaac atgtttttca aagcaaaata
     3241 aagacatc
//
