LOCUS       NM_007675               1060 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus CEA cell adhesion molecule 10 (Ceacam10), transcript
            variant 1, mRNA.
ACCESSION   NM_007675
VERSION     NM_007675.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Patel,V.N., Aure,M.H., Choi,S.H., Ball,J.R., Lane,E.D., Wang,Z.,
            Xu,Y., Zheng,C., Liu,X., Martin,D., Pailin,J.Y., Prochazkova,M.,
            Kulkarni,A.B., van Kuppevelt,T.H., Ambudkar,I.S., Liu,J. and
            Hoffman,M.P.
  TITLE     Specific 3-O-sulfated heparan sulfate domains regulate salivary
            gland basement membrane metabolism and epithelial differentiation
  JOURNAL   Nat Commun 15 (1), 7584 (2024)
   PUBMED   39217171
  REMARK    Erratum:[Nat Commun. 2024 Oct 10;15(1):8784. doi:
            10.1038/s41467-024-53230-4.. PMID: 39389981]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  AUTHORS   Cao,Z., Huang,C., Lu,F., Jiang,X., Hu,Y., Cao,C. and Liu,Z.
  TITLE     Meis1 Regulates Nociceptor Development and Behavioral Response to
            Tactile Stimuli
  JOURNAL   Front Mol Neurosci 15, 901466 (2022)
   PUBMED   35875660
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1060)
  AUTHORS   Minett,M.S., Pereira,V., Sikandar,S., Matsuyama,A., Lolignier,S.,
            Kanellopoulos,A.H., Mancini,F., Iannetti,G.D., Bogdanov,Y.D.,
            Santana-Varela,S., Millet,Q., Baskozos,G., MacAllister,R.,
            Cox,J.J., Zhao,J. and Wood,J.N.
  TITLE     Endogenous opioids contribute to insensitivity to pain in humans
            and mice lacking sodium channel Nav1.7
  JOURNAL   Nat Commun 6, 8967 (2015)
   PUBMED   26634308
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1060)
  AUTHORS   Heckt,T., Bickert,T., Jeschke,A., Seitz,S., Schulze,J., Ito,W.D.,
            Zimmermann,W., Amling,M., Schinke,T., Horst,A.K. and Keller,J.
  TITLE     Increased osteoclastogenesis in mice lacking the carcinoembryonic
            antigen-related cell adhesion molecule 1
  JOURNAL   PLoS One 9 (12), e114360 (2014)
   PUBMED   25490771
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1060)
  AUTHORS   Li,S.H., Lee,R.K., Hsiao,Y.L. and Chen,Y.H.
  TITLE     Demonstration of a glycoprotein derived from the Ceacam10 gene in
            mouse seminal vesicle secretions
  JOURNAL   Biol Reprod 73 (3), 546-553 (2005)
   PUBMED   15901639
  REMARK    GeneRIF: The purification and physiological role of CEACAM10 in
            male mice is reported. [CEACAM]
REFERENCE   6  (bases 1 to 1060)
  AUTHORS   Finkenzeller,D., Fischer,B., Lutz,S., Schrewe,H., Shimizu,T. and
            Zimmermann,W.
  TITLE     Carcinoembryonic antigen-related cell adhesion molecule 10
            expressed specifically early in pregnancy in the decidua is
            dispensable for normal murine development
  JOURNAL   Mol Cell Biol 23 (1), 272-279 (2003)
   PUBMED   12482980
  REMARK    GeneRIF: Taken together, both Ceacam10 and Ceacam9, alone or in
            combination, are not essential for either murine placental and
            embryonic development or for adult life.
REFERENCE   7  (bases 1 to 1060)
  AUTHORS   Kataoka,K., Takata,Y., Nakajima,A., Saito,S. and Huh,N.
  TITLE     A carcinoembryonic antigen family cDNA from mouse placenta encoding
            a protein with a rare domain composition
  JOURNAL   Placenta 21 (7), 610-614 (2000)
   PUBMED   10985962
REFERENCE   8  (bases 1 to 1060)
  AUTHORS   Stubbs,L., Carver,E.A., Shannon,M.E., Kim,J., Geisler,J.,
            Generoso,E.E., Stanford,B.G., Dunn,W.C., Mohrenweiser,H.,
            Zimmermann,W., Watt,S.M. and Ashworth,L.K.
  TITLE     Detailed comparative map of human chromosome 19q and related
            regions of the mouse genome
  JOURNAL   Genomics 35 (3), 499-508 (1996)
   PUBMED   8812484
REFERENCE   9  (bases 1 to 1060)
  AUTHORS   Keck,U., Nedellec,P., Beauchemin,N., Thompson,J. and Zimmermann,W.
  TITLE     The cea10 gene encodes a secreted member of the murine
            carcinoembryonic antigen family and is expressed in the placenta,
            gastrointestinal tract and bone marrow
  JOURNAL   Eur J Biochem 229 (2), 455-464 (1995)
   PUBMED   7744068
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC161488.7, AK018529.1 and BE949028.1.
            
            On May 1, 2009 this sequence version replaced NM_007675.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003346.2, BG518984.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-22                AC161488.7         47652-47673         c
            23-1043             AK018529.1         3-1023
            1044-1060           BE949028.1         1-17                c
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 12.78 cM"
     gene            1..1060
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /note="CEA cell adhesion molecule 10"
                     /db_xref="GeneID:26366"
                     /db_xref="MGI:MGI:1347248"
     exon            1..136
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..870
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; CEA-related cell adhesion molecule 10;
                     carcinoembryonic antigen 10; carcinoembryonic
                     antigen-related cell adhesion molecule 10; cell adhesion
                     molecule CEACAM10"
                     /codon_start=1
                     /product="cell adhesion molecule CEACAM10 isoform 1
                     precursor"
                     /protein_id="NP_031701.3"
                     /db_xref="CCDS:CCDS39833.1"
                     /db_xref="GeneID:26366"
                     /db_xref="MGI:MGI:1347248"
                     /translation="MELASAHLHKGQVPWVGLLLTASLLTYWSPATTAQVTVEAVPPN
                     VTADNNVLLLVHNLPQTLRVFYWYKGNSGAGHNEIGRFVTSINRSKMGLAHSGRETIY
                     SNGSLFFQSVTKNDEGVYTLYMLDQNFEITPISVRFHVHPSLLPSLSPPTTGQVTVEA
                     VRPNVAEGENVLLLVHNLPRTLRAIYWYRGTTAGERNEIARFITASNKIILGPAHSDR
                     EIIYNNGSLFFQGVTKNDEGAYALDMLFQNFDHTLMPVQFNVHAKKQ"
     exon            137..496
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /inference="alignment:Splign:2.1.0"
     exon            497..856
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /inference="alignment:Splign:2.1.0"
     exon            857..1050
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1021..1026
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /note="hexamer: AATAAA"
     polyA_site      1050
                     /gene="Ceacam10"
                     /gene_synonym="Bgp3; Cea10"
                     /note="major polyA site"
ORIGIN      
        1 cagggcagat acctgggcag ccaggcttag cagtagtgtt ggagaagaag ctagcaggca
       61 ggcagcagag acatggagct ggcctcagca catctccaca aagggcaggt tccctgggtt
      121 ggactactgc tcacagcctc acttttaact tactggagcc ctgccactac tgcccaagtc
      181 accgttgagg ctgtgccgcc caacgttact gcagacaaca atgttcttct acttgttcac
      241 aatctgccgc agacgctccg agtcttttac tggtacaagg gaaacagtgg ggctggacac
      301 aatgaaattg gacgatttgt aacatccatt aataggagta aaatggggct tgcacacagc
      361 ggcagagaga caatatatag caatggatcc ctgttcttcc aaagtgtcac caagaatgat
      421 gagggagtct acacattata tatgctagat caaaactttg aaattactcc gatttctgtg
      481 cgatttcatg tacacccctc acttttaccc tccttgagcc ctcccaccac tggccaagtc
      541 accgttgagg ctgtgcggcc caacgttgcc gaaggggaaa acgttcttct acttgttcac
      601 aatctgccac ggacgctccg agcaatttac tggtacaggg gaaccactgc gggtgaaaga
      661 aatgaaattg cacgatttat aacagcctcc aataagatta tattggggcc tgcacacagc
      721 gacagagaga tcatatacaa caatggatcc ctgttcttcc aaggtgtcac caagaatgat
      781 gagggagcct acgcactaga tatgctattt caaaacttcg atcataccct aatgcctgtg
      841 caatttaatg ttcacgctaa aaagcagtag gaattttttt tccagccccc ttgcatttaa
      901 ttcttctttc attgctcttt ctaactggaa ccgaactctg ggaaagaggg ctgatgctca
      961 ctagtgaacc ccagggattt catcagctga cggtgccttg cttcacctcc ttccaccagc
     1021 aataaagtcc gcataacttc tgcaaacaaa aaaaaaaaaa
//
