LOCUS       NM_173370               3855 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus CDP-diacylglycerol synthase 1 (Cds1), transcript
            variant 1, mRNA.
ACCESSION   NM_173370 NM_001417858
VERSION     NM_173370.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3855)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3855)
  AUTHORS   Qi,Y., Kapterian,T.S., Du,X., Ma,Q., Fei,W., Zhang,Y., Huang,X.,
            Dawes,I.W. and Yang,H.
  TITLE     CDP-diacylglycerol synthases regulate the growth of lipid droplets
            and adipocyte development
  JOURNAL   J Lipid Res 57 (5), 767-780 (2016)
   PUBMED   26946540
REFERENCE   3  (bases 1 to 3855)
  AUTHORS   Araujo,D.J., Anderson,A.G., Berto,S., Runnels,W., Harper,M.,
            Ammanuel,S., Rieger,M.A., Huang,H.C., Rajkovich,K., Loerwald,K.W.,
            Dekker,J.D., Tucker,H.O., Dougherty,J.D., Gibson,J.R. and
            Konopka,G.
  TITLE     FoxP1 orchestration of ASD-relevant signaling pathways in the
            striatum
  JOURNAL   Genes Dev 29 (20), 2081-2096 (2015)
   PUBMED   26494785
REFERENCE   4  (bases 1 to 3855)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 3855)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   6  (bases 1 to 3855)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   7  (bases 1 to 3855)
  AUTHORS   Inglis-Broadgate,S.L., Ocaka,L., Banerjee,R., Gaasenbeek,M.,
            Chapple,J.P., Cheetham,M.E., Clark,B.J., Hunt,D.M. and Halford,S.
  TITLE     Isolation and characterization of murine Cds (CDP-diacylglycerol
            synthase) 1 and 2
  JOURNAL   Gene 356, 19-31 (2005)
   PUBMED   16023307
  REMARK    GeneRIF: Cds1 showed a very restricted expression pattern and was
            mapped to chromosome 5E3.
REFERENCE   8  (bases 1 to 3855)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   9  (bases 1 to 3855)
  AUTHORS   Volta,M., Bulfone,A., Gattuso,C., Rossi,E., Mariani,M.,
            Consalez,G.G., Zuffardi,O., Ballabio,A., Banfi,S. and Franco,B.
  TITLE     Identification and characterization of CDS2, a mammalian homolog of
            the Drosophila CDP-diacylglycerol synthase gene
  JOURNAL   Genomics 55 (1), 68-77 (1999)
   PUBMED   9889000
REFERENCE   10 (bases 1 to 3855)
  AUTHORS   Lykidis,A., Jackson,P.D., Rock,C.O. and Jackowski,S.
  TITLE     The role of CDP-diacylglycerol synthetase and phosphatidylinositol
            synthase activity levels in the regulation of cellular
            phosphatidylinositol content
  JOURNAL   J Biol Chem 272 (52), 33402-33409 (1997)
   PUBMED   9407135
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC121983.3, AC172745.4 and AC171108.2.
            
            On or before Mar 14, 2023 this sequence version replaced
            NM_001417858.1, NM_173370.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055292.1, AF533367.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-291               AC121983.3         137528-137818
            292-419             AC121983.3         153704-153831
            420-516             AC172745.4         24698-24794         c
            517-614             AC172745.4         19168-19265         c
            615-754             AC172745.4         17753-17892         c
            755-813             AC172745.4         9648-9706           c
            814-896             AC172745.4         7521-7603           c
            897-984             AC172745.4         6296-6383           c
            985-1053            AC172745.4         3706-3774           c
            1054-1206           AC172745.4         1717-1869           c
            1207-1326           AC172745.4         301-420             c
            1327-1430           AC171108.2         6894-6997
            1431-3855           AC171108.2         10475-12899
FEATURES             Location/Qualifiers
     source          1..3855
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 48.93 cM"
     gene            1..3855
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /note="CDP-diacylglycerol synthase 1"
                     /db_xref="GeneID:74596"
                     /db_xref="MGI:MGI:1921846"
     exon            1..291
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            292..419
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            420..516
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            517..614
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            615..754
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            755..813
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            814..896
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            897..984
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1053
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1206
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1326
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1430
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..3855
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3832..3837
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3855
                     /gene="Cds1"
                     /gene_synonym="4833409J18Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtgcgtgga acggcgcacc tggcaacggc gccgcgtccc cgcccgcgcc ggtccgcaca
       61 ccctgccggc ggcctcgagc gctcgctcgt tgatgccgtt ctgggggtga cccggcgcgg
      121 ctccgcggtg gcggggcgct agacgacgcc agcccagcga cgcgggagcg ggacatgctg
      181 gagctgcggc accgcggggg ctgccccggc cctgggggag cgggggcgcc gccaccccgc
      241 gagggagagg cggccggcgg tgaccacgaa accgagagca ccagcgacaa agaaacagat
      301 attgatgaca ggtatggaga tctcgatgcc agaggcgatt ccgacgtgcc tgaggtccca
      361 ccgtcctcag acaggacccc cgagattctc aagaaagccc tgtccggact atcttcaaga
      421 tggaagaact ggtggattcg cgggatcctc accctcacca tgatctccct cttcttcctg
      481 attatctata tggggtcctt catgctgatg cttctggttc tgggcatcca agtgaagtgc
      541 ttccatgaga tcatcaccat cgggtaccgg gtctaccact cctacgacct cccatggttt
      601 aggacactaa gttggtactt cctcctgtgt gtgaactact tcttctatgg agagacggtg
      661 gcagattact tcgccacgtt tgttcagagg gaggagcagc tgcagttcct cattcgctac
      721 cacaggttca tatccttcgc cctctacctg gcaggtttct gcatgtttgt cctgagcctg
      781 gtgaagaagc actacagact gcagttctat atgttcgcat ggacgcacgt cactttactg
      841 ataaccgtca ctcagtcaca tcttgtcatc caaaatctgt ttgaaggcat gatatggttc
      901 cttgttccca tatcaagcgt catctgcaat gacatcacag cttatctttt tggatttttt
      961 tttggaagaa ctcctctaat taagctgtct cctaagaaga cttgggaagg attcattggt
     1021 ggtttcttct ccacagtcat atttggattc attgctgcct atgtgttgtc caagtaccag
     1081 tactttgtgt gcccggtgga ataccgaagc gacgtcaact ccttcgtgac agagtgtgag
     1141 ccctcagaac tgttccagct tcagaattac tccctccctc cattcctaca ggcagtgctg
     1201 agccgggaga ctgtgagctt gtaccccttc cagatacaca gcattgccct ttcaacgttc
     1261 gcgtcactga ttggcccatt tggaggcttc tttgccagtg gattcaaaag agctttcaaa
     1321 atcaaggatt ttgcaaacac gattcctgga catggcggga taatggacag gtttgactgt
     1381 cagtatttga tggcaacgtt cgtgcacgtg tacatcacca gcttcatcag gggtccgaat
     1441 cccagcaaag tgctccagca gctgttagtg cttcaaccag aacagcagtt aaatatctac
     1501 agaaccctga agattcatct caccgagaaa gggatcctgc agcccacctt gaaggtgtag
     1561 ctgcccttga ggacgacggg ctgctgagga ggagctcaca gaccagctct gactggagcc
     1621 gtgcactgag ccagcctggg gctaaaactc agtagatgca ggctttgcag atacaaaggt
     1681 ttctttttct gaatttacaa ttactgtgaa tatttaacaa acacgtggtc taaggtgagt
     1741 gcagcagtcg cccacccgtg aaagatcctg tacttttcta aaatgtattt tccaatgtta
     1801 agttctctgc cctcactggc caggttccat gatttaggta gacttgcgtt ttaaagagtc
     1861 aaacactatc aactgaggcc ctcgtagggt gttgaccttt gccctggtgc tgccctggcg
     1921 tagccatagc tgaatgcact ggaggcacct tgggaatcga ggtctcgggg tttcctcctc
     1981 taatgatctc aagcatttct gaagggctga gttagattaa aaagaaagaa aaagagcgat
     2041 tgtccacttt tctctctctt ctttttgttt gtttgttcat ggtactgggc tagaacccag
     2101 ggtccggtcc acaccaggca ggtgccccac tcttgggctc cgccttggct gggccgccta
     2161 ctttcagagt agcagtcatc tgccaagtgt taacgccctg gtgttaagga gtttcaaaat
     2221 cagaagctag aggctggtgc ttagaccact gttgatttgt tgaaaaagaa gttatcagaa
     2281 tccatttctg atgcaaaaga gactcagagt gggtcctgca tggcgagccc agcacgaggc
     2341 tcctccacca gaaatacctc accagggatg gtagggatga gtggtgtgtg gtggtggctg
     2401 gggagccacc tggaaaggag agttttccct aaagacccag ctccaggcca gccccctgct
     2461 ggtaattaac ctctgtcacc ttgcacttcc tgaacccaag aataaaagta cagcagaaac
     2521 agcagccatg aagcaggaaa gcctacaaat gccacacctt gcccctgtgc aggtggggcc
     2581 ggaccctgtg agtggactag gggatctcct gttgctgtgt gtgctctgca gccatactta
     2641 accaaatgtc gcggtcaccc gcagagacga cctggagggg gagaaatgga gatgctgcag
     2701 aggatagttt ggtaatgaaa agagtaaata ttttgtttaa gttagaaatc acccatattt
     2761 ccttcccact gtggatgcgc tagggttctg aggaggagcc cacaggcatc agtagcagtc
     2821 ctgagaacac cattgttggc ccccaggtga ctggtgaccc tgcgctggat tcagcccacg
     2881 ccctctgcat acaagccagg ggagcgctgt caccttagga gatcccctct cagtggctga
     2941 tgtcagtgtc ccctgctttt gtgtgtcccc ccgccccgcc ccagatgttg accataaatg
     3001 agttgcaggc acaaaagaaa tggagggaag ccttgtggta ggagcatgtc caggaacagg
     3061 ctgtctgcag aggtaaagga tggttgagga catggtggct tctccttacc caccatgctc
     3121 tcatggcttg cgaggcagaa ttatggaagc attacttaat acacgtatta aaaatcaata
     3181 ttctaaacac aaaggatgaa actaggacta tctggggtta caataaaagc tcttctcaat
     3241 tagatctttt agagctgggt gtacattatg ccatataaaa acaagcgagt tctttaacaa
     3301 caacactcta gtaatgaaca ttttagccta ctttttatag cgtgtacatt aaagtggact
     3361 atagcaaaca accaccgtga gagcgactgt gaccagcgtt ccatttgcac tggaacaggc
     3421 gtcatccagt ggagtgaagt ggtggatgag tggcaaccag gaaggccctc cacagcagag
     3481 atccatcgat ggaaaatcga cctttgaact gctgtctgac ctggtagctt ttgggatggt
     3541 gatgtctgag aaccagggcg ctctccctag tcttccttgt ggattcacac agacagttgc
     3601 tgtccgagat taaaggctgc ccccactttt gtccctttgc actttgaaca gaggtcatgg
     3661 cgacacctgg tctgatgaga agaaaggtcg agacagtgtg gatatactgt acggggtgag
     3721 agtttattat atgtgtctat cagccctcag cgctgtggat atatatactg tagagcttat
     3781 gatatgtgtc aatcagtcct ctgaatcttt ttactgaaac tgggatagaa aaataaagat
     3841 ccaatggtat tttga
//
