LOCUS       NM_001405247            7635 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Mus musculus cell adhesion molecule-related/down-regulated by
            oncogenes (Cdon), transcript variant 2, mRNA.
ACCESSION   NM_001405247 XM_011242581
VERSION     NM_001405247.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7635)
  AUTHORS   Franks,N.E. and Allen,B.L.
  TITLE     Hedgehog-dependent and hedgehog-independent roles for growth arrest
            specific 1 in mammalian kidney morphogenesis
  JOURNAL   Development 151 (24) (2024)
   PUBMED   39629522
REFERENCE   2  (bases 1 to 7635)
  AUTHORS   Kumari,A., Franks,N.E., Li,L., Audu,G., Liskowicz,S., Johnson,J.D.,
            Mistretta,C.M. and Allen,B.L.
  TITLE     Distinct expression patterns of Hedgehog signaling components in
            mouse gustatory system during postnatal tongue development and
            adult homeostasis
  JOURNAL   PLoS One 19 (6), e0294835 (2024)
   PUBMED   38848388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7635)
  AUTHORS   Leung,A.O.W., Poon,A.C.H., Wang,X., Feng,C., Chen,P., Zheng,Z.,
            To,M.K., Chan,W.C.W., Cheung,M. and Chan,D.
  TITLE     Suppression of apoptosis impairs phalangeal joint formation in the
            pathogenesis of brachydactyly type A1
  JOURNAL   Nat Commun 15 (1), 2229 (2024)
   PUBMED   38472182
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7635)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 7635)
  AUTHORS   Kim,J.M., Min,K.W., Kim,Y.J., Smits,R., Basler,K. and Kim,J.W.
  TITLE     Wnt/beta-Catenin Signaling Pathway Is Necessary for the
            Specification but Not the Maintenance of the Mouse Retinal Pigment
            Epithelium
  JOURNAL   Mol Cells 46 (7), 441-450 (2023)
   PUBMED   37190767
REFERENCE   6  (bases 1 to 7635)
  AUTHORS   Cole,F. and Krauss,R.S.
  TITLE     Microform holoprosencephaly in mice that lack the Ig superfamily
            member Cdon
  JOURNAL   Curr Biol 13 (5), 411-415 (2003)
   PUBMED   12620190
REFERENCE   7  (bases 1 to 7635)
  AUTHORS   Kang,J.S., Mulieri,P.J., Hu,Y., Taliana,L. and Krauss,R.S.
  TITLE     BOC, an Ig superfamily member, associates with CDO to positively
            regulate myogenic differentiation
  JOURNAL   EMBO J 21 (1-2), 114-124 (2002)
   PUBMED   11782431
REFERENCE   8  (bases 1 to 7635)
  AUTHORS   Mulieri,P.J., Okada,A., Sassoon,D.A., McConnell,S.K. and
            Krauss,R.S.
  TITLE     Developmental expression pattern of the cdo gene
  JOURNAL   Dev Dyn 219 (1), 40-49 (2000)
   PUBMED   10974670
REFERENCE   9  (bases 1 to 7635)
  AUTHORS   Kang,J.S., Mulieri,P.J., Miller,C., Sassoon,D.A. and Krauss,R.S.
  TITLE     CDO, a robo-related cell surface protein that mediates myogenic
            differentiation
  JOURNAL   J Cell Biol 143 (2), 403-413 (1998)
   PUBMED   9786951
REFERENCE   10 (bases 1 to 7635)
  AUTHORS   Kang,J.S., Gao,M., Feinleib,J.L., Cotter,P.D., Guadagno,S.N. and
            Krauss,R.S.
  TITLE     CDO: an oncogene-, serum-, and anchorage-regulated member of the
            Ig/fibronectin type III repeat family
  JOURNAL   J Cell Biol 138 (1), 203-213 (1997)
   PUBMED   9214393
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC159894.2 and AC118232.10.
            
            On Apr 21, 2022 this sequence version replaced XM_011242581.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR9219381.195525.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN00849374, SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               AC159894.2         84305-84571         c
            268-390             AC159894.2         75260-75382         c
            391-523             AC159894.2         53943-54075         c
            524-796             AC159894.2         53187-53459         c
            797-943             AC159894.2         51671-51817         c
            944-1087            AC159894.2         50654-50797         c
            1088-1375           AC159894.2         49385-49672         c
            1376-1645           AC159894.2         48454-48723         c
            1646-1999           AC159894.2         41892-42245         c
            2000-2289           AC159894.2         35966-36255         c
            2290-2464           AC159894.2         34961-35135         c
            2465-2596           AC159894.2         32555-32686         c
            2597-2800           AC159894.2         29040-29243         c
            2801-2982           AC159894.2         27988-28169         c
            2983-3088           AC159894.2         27431-27536         c
            3089-3211           AC159894.2         22900-23022         c
            3212-3433           AC159894.2         19149-19370         c
            3434-3699           AC159894.2         16880-17145         c
            3700-3779           AC159894.2         14196-14275         c
            3780-4039           AC159894.2         2701-2960           c
            4040-6102           AC159894.2         1-2063              c
            6103-7635           AC118232.10        144175-145707       c
FEATURES             Location/Qualifiers
     source          1..7635
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 20.24 cM"
     gene            1..7635
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /note="cell adhesion molecule-related/down-regulated by
                     oncogenes"
                     /db_xref="GeneID:57810"
                     /db_xref="MGI:MGI:1926387"
     exon            1..267
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            268..390
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            391..523
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     CDS             451..4203
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /note="oncogene-regulated cell adhesion molecule;
                     immunoglobulin superfamily member CDO;
                     CAM-related/down-regulated by oncogenes"
                     /codon_start=1
                     /product="cell adhesion molecule-related/down-regulated by
                     oncogenes precursor"
                     /protein_id="NP_001392176.1"
                     /db_xref="GeneID:57810"
                     /db_xref="MGI:MGI:1926387"
                     /translation="MHPDLGPLWTLLYVLVILCSSVSSDLAPYFISEPLSAVQKLGRP
                     VVLHCSAKPVTARISWLHNGKRLDRNTEQIKIHRGTLTILSLNPSLSGCYQCVANNSV
                     GAVVSGPATVSAAALGDFDSSTMHVITAEEKNTGFIGCRVPESNPKAEVRYKIRGKWL
                     KHSTGNYIILPSGNLQVLNVSSKDKGSYKCAAYNPVTSELKVEPTGRKLLVSRPSSNG
                     FHILHPALSQALAVLPHSPVTLECVVSGVPASQVYWLKDGQDAVAGSNWRRLYSHLAT
                     ASIDPADSGNYSCVVGNKSGDVKHVTYMVNVLEHASISKGLHDQKVSLGATVHFTCDV
                     HGNPAPNRTWFHNAQPIHPSSRHLTEGNVLKITRVVMEDSGLYQCVADNGIGFMQSTG
                     RLQIEQDSGWKPVIVTAPANIEVMDGDFVTLSCNATGVPVPVIHWYGRHGLITSHPSQ
                     VLRSKPRKSHLFRPGDLDLEPVYLIMSQAGSSSLSIQAVTLEHAGKYTCEATNKHGST
                     QSEAFLTVVPFETNTKAESVTPSEASQNDERDPQDGSESSLLNLFPVKVHPSGVELPA
                     ERNASVPDAPNILSPPQTHMPDTYNLVWRAGRDGGMPINAYFVKYRKLDDGSGAVGSW
                     HTVRVPGSENELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNTQA
                     SFPPVGVPKRPVTAEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTWIPR
                     ANGGSPITAFKVEYKRMRTSDWLVAAEDIPPSKLSVEVRSLEPGSIYKFRVIAINHYG
                     ESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYVPSSNNNTPIQ
                     GFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSNV
                     MICETKVKRVPGASDYPVKELSTPPSSSGNAGNVGPATSPARSSDMLYLIVGCVLGVM
                     VLILMVFIALCLWKSRQQSTIQKYDPPGYLYQGSEINGQMVEYTTLSGAARINGSVHG
                     GFLSNGCSHLHHKGPSGVNGTLSGNINGGLYSAHTNSLTRACVEFEHPHHLVNSGGVY
                     TAVPQMDPLECINCRNCRNNNRCFTKTNSPLPVVPVVASYPQGGLEMKPLNAMKVPVC
                     PASTVPDHGQLPDDCVKDSVAPIPTQHTCCQDNISDINSDSTEDTAEFSRGDSSGHSE
                     AEDKVFSWNPLILSPVLEDCGEKTARSPPGPPLDGLSVVLQQAQET"
     exon            524..796
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            797..943
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1087
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            1088..1375
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1645
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1999
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            2000..2289
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            2290..2464
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            2465..2596
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            2597..2800
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2982
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            2983..3088
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            3089..3211
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            3212..3433
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            3434..3699
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            3700..3779
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            3780..4039
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     exon            4040..7635
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7607..7612
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /note="hexamer: ATTAAA"
     polyA_site      7629
                     /gene="Cdon"
                     /gene_synonym="Cd0; CDO; Orcam"
                     /note="major polyA site"
ORIGIN      
        1 actccgcccc ccagctcccc tcccggagcc cgggtgcccg gctcgcgcgg ctcggtacga
       61 gacggggacc tcgcgccgcc ccagtgcccc cgccccgcgt gagaggcgcc gcgccctccg
      121 gccgtcctgc ccggtgcatg gaggggcccg ttcggatcgc agccaccgcc gccgccgccg
      181 ccagcgtgcg gggggatgac ctgggggtgg ctctcggagc cggctgctgt gcaggaggtc
      241 tcggggctta gccagccctg cggagagctg cgtgagagca caggctccta tgtcatgggc
      301 atccagtgcc gtgctctgct tcacgtgagg cccgtggagg tggagctgct caccaccatg
      361 gaccaaaccc tctgaagtca cgcgccaaaa taagcggagg cctgggcttt ctctgcaagt
      421 cttcccagcc tacttctgta attgggcgat atgcatccag acctcggacc cttatggaca
      481 ttgctgtatg ttcttgtgat tctgtgttct tctgtgagct cagacttggc accttatttt
      541 atttctgagc cactctctgc tgtccagaag cttggtagac ccgtggtcct acattgttct
      601 gctaaacctg ttactgcccg aatctcatgg ttgcataatg gaaaacggtt ggacagaaac
      661 acagaacaga taaagattca tcgggggact ttgaccattc tgtctcttaa cccttccctt
      721 tctggttgct accagtgcgt tgccaacaac agcgttggtg ccgttgtgag cggccccgca
      781 acagtgtccg ctgcagccct gggtgatttc gattcatcaa caatgcacgt tattactgca
      841 gaagagaaaa acacaggctt cattggctgc agggtaccag agagtaaccc caaagctgag
      901 gtgcgctata agatccgggg aaagtggctg aagcattcca cagggaacta cataatcctt
      961 ccctcaggaa accttcaggt tctgaatgtg tcctctaagg ataagggatc ctacaaatgt
     1021 gctgcctata accctgtcac cagtgaactg aaggttgagc ccactggccg gaagctcctt
     1081 gtgagtcgtc cttcctcgaa tggctttcac attcttcacc ctgctctttc tcaggcatta
     1141 gctgtccttc ctcacagccc cgttaccttg gagtgtgtgg tgagtggggt tccggcctca
     1201 caagtgtatt ggctgaagga cggtcaggat gccgtggcag gaagcaactg gagaaggctg
     1261 tactctcatc tggccacagc tagcatcgac ccagcggatt cggggaacta ttcctgtgtg
     1321 gtgggcaaca agtccggaga tgtgaaacac gtcacttaca tggtcaatgt actggagcat
     1381 gcgtcaattt ctaaagggct gcacgatcag aaggtgtccc tgggggccac cgtacatttt
     1441 acctgtgatg ttcatgggaa cccagccccc aaccgcacct ggtttcataa cgcacagcct
     1501 atccacccct cctcacggca tctcactgaa ggaaacgtgc tgaagatcac ccgggttgtc
     1561 atggaagatt ctgggctata tcagtgcgta gcagacaatg gcattggatt catgcagtct
     1621 actgggagac ttcaaattga acaagacagt ggatggaagc ctgttattgt caccgcacca
     1681 gcaaacatag aggtgatgga tggagacttt gtgactttgt cttgtaatgc caccggagtg
     1741 cctgtcccag tcattcattg gtacggccgc catggattga taaccagcca tccatctcag
     1801 gtccttaggt ccaaaccccg aaagtcccac ctgttccggc ctggggacct ggacctggag
     1861 cctgtctacc tcatcatgtc ccaagctggc tcgagctctc tgtctattca ggcagtcact
     1921 ctggagcatg ctgggaaata tacttgtgaa gctacaaaca aacatggcag cacacagtca
     1981 gaagcattcc tcacagttgt tcctttcgag acaaacacaa aggcagagtc agtcacacct
     2041 tctgaagctt ctcagaatga tgagcgagac ccacaagacg gttcagagtc cagcctgctg
     2101 aacttgtttc cagtgaaggt gcatcccagt ggagtggaat tgccagcaga gagaaatgcc
     2161 tcggtccccg atgctcctaa catactgagc cccccacaga ctcacatgcc agacacgtac
     2221 aacctggtgt ggagggcagg gagggatggc ggaatgccca tcaacgccta tttcgtgaag
     2281 taccgaaagc tggacgatgg tagtggtgca gtgggcagct ggcacacagt tcgtgtccca
     2341 gggagtgaaa atgagctgca tctaactgag ctggagccat caagtctcta tgaagttttg
     2401 atggtggcta gaagtgcagt tggtgaagga cagcctgcca tgcttacctt ccggaccagc
     2461 aaagaaaaaa tggcgtcatc aaaaaacacc caggcctcct ttccgcctgt gggcgtcccc
     2521 aagcggcctg ttactgcaga ggcttccaac agcaattttg gagttgtgct tacggattcc
     2581 tccaggcata gtggagtccc agaggcacca gatcgaccta ctatctctat ggcgtcggag
     2641 acctcagtct atgtcacctg gattccccga gcaaatggtg gctctcccat caccgccttc
     2701 aaggtggaat ataaacggat gagaactagt gattggctgg tagcggctga agacattcct
     2761 ccttccaaac tctctgtgga agttcgtagt ttagagccag gttcaatata caaatttagg
     2821 gtcattgcta tcaaccatta cggtgagagt tttcggagct cagcatcccg tccttaccag
     2881 gtggccggct tcccaaatcg tttttccaat cgcccaataa ctggacctca catcgcatac
     2941 acagaggctg ttagcgacac tcagatcatg ctgaaatgga cgtatgttcc atcaagtaac
     3001 aataatactc ccattcaagg attctatatc tactaccggc caacagacag tgacaatgac
     3061 agtgactaca agagagacgt tgtggaaggc tcaaagcagt ggcacaccat tggtcacctg
     3121 cagccagaga cctcctatga cattaagatg cagtgcttta atgaaggagg ggagagtgag
     3181 ttcagcaacg tgatgatctg cgagactaaa gtaaaacgtg ttcctggagc ttccgactat
     3241 cccgtgaaag agttgagtac ccctcccagt tcctcgggaa acgcagggaa cgtggggcct
     3301 gcaaccagcc ccgccaggag cagcgatatg ttgtacctca tcgttggctg tgtgcttggg
     3361 gttatggtcc tcattcttat ggttttcatt gcgctgtgtc tgtggaagag tcgccaacag
     3421 agcaccatac agaaatatga tcctccagga tatctctacc aggggtcaga gattaatggg
     3481 cagatggtag agtataccac tctctcagga gcagcccgga tcaacgggag tgttcacgga
     3541 ggcttcctca gcaatggctg ttctcatctg caccataaag gccccagtgg agtcaacggg
     3601 accctgagtg gaaacataaa tggaggcctt tattctgcac acacaaactc cctgaccagg
     3661 gcgtgtgtgg agtttgagca tcctcaccat ctagtgaata gtggaggagt gtacacagcc
     3721 gtccctcaga tggacccact ggaatgcatt aattgtcgga attgccggaa caacaatagg
     3781 tgtttcacca aaaccaacag tccccttcct gtggtcccag tggtagcctc ttatcctcag
     3841 ggtggtctgg aaatgaagcc cctcaatgcc atgaaggtgc ctgtgtgccc agcttccaca
     3901 gttcctgacc atggccagtt acctgacgat tgtgtcaagg acagtgtggc accaatacct
     3961 acccagcata cttgctgcca ggacaacata agtgacatca attctgattc cacagaagac
     4021 acagcagagt tcagcagagg agacagcagt ggtcattctg aagcagagga caaagttttc
     4081 agttggaatc ctcttatttt gtcacctgtc ttggaggact gtggtgagaa gacagcgagg
     4141 tctccccctg gacctcctct agacgggctg tcggtggtcc ttcagcaagc ccaagagacc
     4201 tgagaggagt gtgagcagac ctcttcgtgt tcccactgca agccagtaac tgtaccacac
     4261 aggcctgggg acaaactgtg tgaaggacat taattcaaat cagagaaaac cattatttat
     4321 tttttgtaat agtcatgtca tgaatgtatc ttaaaatgtg tgccctttca tattatttat
     4381 gccttacctt ttcccttctc catttcgtcc tgcccctgga taggaccccc cccccgtttt
     4441 tgttttgttt gttttgtttt aacagagctt ttcaatcatc tggaaaacag gggatcactc
     4501 tgtgtcttcc agggtcttcc gtggcagtag gaacttgtgc tgggtcccat cctcaggcct
     4561 gttcagttgt ggggaggagg gttgcccaag ccacttcaca tttgtcacca gtcattccta
     4621 gatggaaaac tgtcacttct cccgtgtcat cagactttct gggaacattt agaaatcaac
     4681 catagttgtg atcatttgtt tataatagcc aacccaactg acagattttt tttgactgcc
     4741 ttccagaaaa acactaatac tgatttattt tctctctggc ctggctacga atagtgatca
     4801 gtcttctagg tttcaaccag ccagtgttgt tatgaacacg gaagcatgta aagtctgtct
     4861 ggattattgt attatgtaga cagggaacca gactcagaaa gaaaattaat tccttcatgg
     4921 tccactgctt tcttaattta caaaatggtt gtcatgagtt ctttgcactg cttgcaaggg
     4981 tatataatac aaaaatgagg cttttaaagt gatagtttga agagaaagct gttacacgcc
     5041 tcaagaaaga gaagggctga agggacctct gagtgaagct cttccgttga tcctatagta
     5101 cttgtgatgc tcaactactt ggagactgat atttgtgtca cttctaacat agacagtgtc
     5161 ctggaggatc tgagtgagca tgtgtgagtc aaccttctgc cactatagca aaattcctga
     5221 ggtgattgtc ttataaggac gcagggttat cttggttccc aagcttagtt ctagtttgtg
     5281 attgaataga cctgtagctt tgggcctgtg ttgagggagc acatcatggt ggatatgcat
     5341 ggcagagcaa aatagcttat accacaaacc agaagagggg gagaacgaga agaacagagt
     5401 gtacaagtcc ccctctcccc caagagcatg cctcagtgat cagaagacct cacacttccc
     5461 tgctcaagat tctaccatct cgggaacatg ttgtcatggg actcagacct tgaacacaga
     5521 gatggatagg cctttggaaa acagtatcca aaccaaagca gaatgccggg aaaggcttag
     5581 tttgaagaaa gggtttgagg gcatttttgg atagtttttc tggtcgctgt cattatgaac
     5641 agtaactgag gcttcagtca gcaggatcca tgcaagcagt tactggtctc tgagtgacaa
     5701 ggacatcgcg gctgcctttg gaaggctttt catacaaacg tgtgaaatag aaaccccagg
     5761 tgctacaaat gcatttcagt aacttgaacc aggccctgat ggatcacaga tctgcttttg
     5821 aatggtgtat cccttggggg ggggggggcg cggggggggg ggacaacaaa attattctct
     5881 ttatgtggaa tcagacaatt ccaggataca ttttgttttc atttcccaca aattgcagtg
     5941 aaagagaata agatactgta ctaatcaact ttatatacat ttgtcagtat tcccttacat
     6001 atgtctgtat cttttataaa tagaactgtt tgtggaaatg tactgtttca gcaggggcca
     6061 ctacgcaagc gttccttctg aaaaatgcag taaatagaat tccatagctg ggtagcgggc
     6121 tgctgtagaa gcgagttcta tgatcctggg gttcatggcc atagtataag agatatgcag
     6181 ttagttttgg aggtagtttg tagccttaca tcttgacttg caaagtacgg tgtagagacc
     6241 tactgtgtgc tttgccagtt gagttgaaac aaagttgtct cagagtcggg gttttggaaa
     6301 gcgggaaaca aatgtctgtg ggcagtcagt tgttcactgt aactcatgaa acaggtatgc
     6361 tggctcgagc cttaggtcag aactgctttt aaagattgaa tttgacatgg ggcttgccca
     6421 tgaggaagat gaaattcctt tacctttagg gcaatctcat tgtggactgc tttatttatg
     6481 attagtaacg ctgttttaag tgttaaccct tttattgtat tttatttata aaaatggctt
     6541 tatatattga gatatataaa tataaatata aatctatata attgccttta tatttaggag
     6601 tttgagttct ccttattgtg agtttctgtg aacttttgtg ccctgcacag tcaccagaaa
     6661 tggtcctagt aagtgtcact tccccaggaa tcaagaggac ataggaaaat gtgggggagg
     6721 ggtcaccagt cattccaaaa tggaatggtg cgcatttgtg gagaaacgat tgtttattag
     6781 ccccctgttt tctcatctga cctccacaac aaatagagta ggcatggaat tcccggccga
     6841 caagtgagct agagcctgct ctggagccta ctctacctga cccatcacca cgcccccttt
     6901 acctgctttc tggaagtgtt atggttcact ctccgtggaa ccagtccaga acgtgtgctg
     6961 ttgtccaccc ctgctgcagc tggtggggct tccctctgtc cacccgcatc tcagactggc
     7021 agagctcttt accaagtact tcatgttcgg gaatctctcc ttgatactct acccttaccc
     7081 tcacccaatc ccaccctttc ctaacctcat gaagatttaa ccatcaactg gcccactgac
     7141 catgaagctg gtaggggctc ttcgtggttc gggagagcct ttgttcagca ttaagcttcc
     7201 ctagtcctag taaatcatgt ctccttttcc tggttttgtt caccaattat gtgactggct
     7261 ctggtgacgg gtgctgtaca gggtacaggt taattgtgtc attctaaact gttgaggtga
     7321 tctcattgtt aaacggttct tgctgggttc tctttgtaca gttgttactc caggctgatc
     7381 acgtcacatc tctgcgtcag ctccagcact accgagagac tgttcggaac tgtcctttct
     7441 ttacctgtat tgctcgctct tacagcattg gccctgcgat gcatgccttg tgctatattg
     7501 aaaaaatatg ttttattttc cttaaagttg tgctgttatg tgtgaagttg tacatactct
     7561 aagtgatgta gttttgacag gttttatttg gttggcatga ttttatatta aaagagaatg
     7621 ctgctttcac gtgca
//
