LOCUS       NM_153785               2765 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus cyclin dependent kinase like 3 (Cdkl3), transcript
            variant 2, mRNA.
ACCESSION   NM_153785
VERSION     NM_153785.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2765)
  AUTHORS   Bardot,P., Vincent,S.D., Fournier,M., Hubaud,A., Joint,M., Tora,L.
            and Pourquie,O.
  TITLE     The TAF10-containing TFIID and SAGA transcriptional complexes are
            dispensable for early somitogenesis in the mouse embryo
  JOURNAL   Development 144 (20), 3808-3818 (2017)
   PUBMED   28893950
REFERENCE   2  (bases 1 to 2765)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   3  (bases 1 to 2765)
  AUTHORS   Liu,Z. and Tao,D.
  TITLE     Inactivition of CDKL3 mildly inhibits proliferation of cells at
            VZ/SVZ in brain
  JOURNAL   Neurol Sci 36 (2), 297-302 (2015)
   PUBMED   25270654
  REMARK    GeneRIF: Results indicated that CDKL3 may be involved in
            proliferation of cells surrounding the brain ventricle where
            neuronal progenitor cells are enriched during the late embryo st
REFERENCE   4  (bases 1 to 2765)
  AUTHORS   Alvarez-Dominguez,J.R., Hu,W., Yuan,B., Shi,J., Park,S.S.,
            Gromatzky,A.A., van Oudenaarden,A. and Lodish,H.F.
  TITLE     Global discovery of erythroid long noncoding RNAs reveals novel
            regulators of red cell maturation
  JOURNAL   Blood 123 (4), 570-581 (2014)
   PUBMED   24200680
REFERENCE   5  (bases 1 to 2765)
  AUTHORS   Harrow,J.L., Steward,C.A., Frankish,A., Gilbert,J.G.,
            Gonzalez,J.M., Loveland,J.E., Mudge,J., Sheppard,D., Thomas,M.,
            Trevanion,S. and Wilming,L.G.
  TITLE     The Vertebrate Genome Annotation browser 10 years on
  JOURNAL   Nucleic Acids Res 42 (Database issue), D771-D779 (2014)
   PUBMED   24316575
REFERENCE   6  (bases 1 to 2765)
  AUTHORS   Liu,Z., Xu,D., Zhao,Y. and Zheng,J.
  TITLE     Non-syndromic mild mental retardation candidate gene CDKL3
            regulates neuronal morphogenesis
  JOURNAL   Neurobiol Dis 39 (3), 242-251 (2010)
   PUBMED   20347982
  REMARK    GeneRIF: CDKL3 is involved in neuronal morphogenesis during
            development.
REFERENCE   7  (bases 1 to 2765)
  AUTHORS   Dubos,A., Pannetier,S. and Hanauer,A.
  TITLE     Inactivation of the CDKL3 gene at 5q31.1 by a balanced t(X;5)
            translocation associated with nonspecific mild mental retardation
  JOURNAL   Am J Med Genet A 146A (10), 1267-1279 (2008)
   PUBMED   18412109
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK046394.1, AK045356.1 and AL669920.15.
            
            On Oct 31, 2009 this sequence version replaced NM_153785.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045356.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               AK046394.1         2-102
            102-762             AK045356.1         2-662
            763-763             AL669920.15        184086-184086
            764-2765            AK045356.1         664-2665
FEATURES             Location/Qualifiers
     source          1..2765
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 31.85 cM"
     gene            1..2765
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /note="cyclin dependent kinase like 3"
                     /db_xref="GeneID:213084"
                     /db_xref="MGI:MGI:2388268"
     exon            1..290
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            291..470
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            471..665
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            666..844
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            845..957
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1097
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1186
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1346
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1675
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1676..1769
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1932
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1933..2030
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2765
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2120..2125
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /note="hexamer: AATACA"
     polyA_site      2139
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
     regulatory      2304..2309
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /note="hexamer: TATAAA"
     polyA_site      2330
                     /gene="Cdkl3"
                     /gene_synonym="B230379H01Rik"
                     /note="major polyA site"
ORIGIN      
        1 aatttccagt cttgcgtact gtgctcggaa cgcggcagtg ccccgccctc accccgttgc
       61 cagggcgtcc ggctgccccg agccggcaag gtcggccagg agaggaggtg tggtgtcccg
      121 ggccggctgg gacttgcacg cagccgggcc ggcgggacta caggatgggc tgaggcggcg
      181 gtggttctca ggacgaggtc gacagcgcgg cgagacgggc cactcgggtt ggggctgcac
      241 agactgcgtg tttgaggaga gggcaggacg tatgggtgac tagtgctgag aagccaggct
      301 tgaaaatgga gatgtatgaa acccttggaa aagtgggaga gggaagttat ggaacggtca
      361 tgaaatgcaa acataaggac actgggcgaa tagtggccat taagattttc tatgagaaac
      421 cagaaaaatc tgtcaacaaa attgcaacga gagaaataaa gtttctaaag caatttcggc
      481 atgaaaacct ggtcaatttg attgaagttt ttagacaaaa gaagaaaatt catttggtat
      541 ttgagtttat tgaccacacg gtcttagatg agctgcagca ctactgtcac ggactagaga
      601 gtaagcggct gagaaagtac ctcttccaga tccttcgcgc cattgagtac ctgcataata
      661 ataatattat ccatcgagat ataaagcctg agaatatttt agtctcccag tcaggaatta
      721 cgaagctgtg tgattttggg tttgcgagga cactagcagc tcctggagac gtttacacag
      781 actacgtggc cacacgctgg tacagagctc cagagctggt gttgaaagac acctcctacg
      841 gaaagccagt ggacatctgg gctttgggct gtatgatcat tgaaatggcc actggccatc
      901 ccttccttcc tagcagttcc gatttggatt tgctccacaa gattgtttta aaagtaggca
      961 acctgacccc gcacctgcac aatatctttt ccaagagtcc catctttgct ggggtggttc
     1021 ttcctcaagt tcaacaccca aaaaccgcaa gaaagaaata ccccaagctc aatggattgc
     1081 tggcagatat agttcatgct tgtttacaaa ttgatcctgc tgagaggaca tcatctactg
     1141 atcttttgcg tcacgattac tttactagag atggatttat tgagaaattc ataccagagc
     1201 tgagagctaa attattacag gaagcaaagg ttaattcatt tataaagcca aaagagaatt
     1261 ttaaagaaaa tgaacctgtg agagatgaga agaaatcagt ttttaccaac accctgctct
     1321 atggaaatcc atcactttat ggcaaggaag tggacagaga caaaagggcc aaggagctca
     1381 aagtcagagt cattaaggcc aaagggggca aaggagatgt cccagaccag aagaagccag
     1441 agtatgaagg cgaccaccgc cagcagggca cagctgatga cacacagccc tcatcactgg
     1501 acaagaagcc ttctgtcttg gaactgacaa accctctcaa tcccagtgag aattctgacg
     1561 gtgtcaaaga agacccacac gctgggggtt gtatgataat gccacctatc aacctgacaa
     1621 gcagtaattt gttggccgca aatctcagtt caaacctttc ccaccccaat tcacggttaa
     1681 ctgaaagaac aaaaaagaga cgcacttctt cacaaactat tggacagact ttgtctaata
     1741 gcagacaaga ggacacaggt cccacacaag tccaaacaga gaaaggtgca tttaatgagc
     1801 gaacaggtca gaatgaccaa atatcgagtg ggaacaaaag aaagctgaat tttcccaaat
     1861 gcgacaggaa agaattccat ttccctgaac tgccattcac agtgcaggcg aaggagatga
     1921 aagggatgga agttaaacag ataaaagtgc tgaagagaga atcaaagaaa acagattcat
     1981 ctaaaatacc aactttactt agtatggacc caaatcaaga aaaacaagag ggtggagatg
     2041 gcgattgtga ggggaagaat ttgaagagga acagattttt tttttcccga tagtgctttg
     2101 tcttttaagt aatcttaaaa atacaagctt gacaattcct tcctttttat tttatataca
     2161 ctagaatgta cataggttgc tgctaagata gccacccatc ccatctgcat caacatcatc
     2221 tatttttttg gttttgctag caaaattttc acaatttttc tctatcttcc aaaaactgtt
     2281 attttgatgc tgtgatttga aattataaag tcacctcctc tgtctgcttc cttccttgcc
     2341 atgattactg agtgggtagt cacatgatgt gccctgctcg cactgctctc agactgctga
     2401 gactcaaacc tcataagcca ggggtctcct gggaagcact ggcctcttca agtggatgct
     2461 cgatgaacct tcttatctgt tgtcttagta accactcgtt gccatcacat gatgaaagac
     2521 attctattgt ccccagtgaa gcatttatag tacttacata acatgttaca gtgatatgat
     2581 gttcctaggt taaactcctt gagatgaaac tatttcctgc attctctgac tcccctagtc
     2641 taatagttcc ttccatttag ccagaagaat ttcctgaaga agcgatgcac aacctgggaa
     2701 aggtttactt tctatcctgg gctgttttct gttgctaaat aatatagact gggtagttag
     2761 ttaac
//
