LOCUS       NM_027118               6901 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus cyclin dependent kinase 13 (Cdk13), transcript variant
            2, mRNA.
ACCESSION   NM_027118
VERSION     NM_027118.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6901)
  AUTHORS   Hampl,M., Jandova,N., Luskova,D., Novakova,M., Szotkowska,T.,
            Cada,S., Prochazka,J., Kohoutek,J. and Buchtova,M.
  TITLE     Early embryogenesis in CHDFIDD mouse model reveals facial clefts
            and altered cranial neurogenesis
  JOURNAL   Dis Model Mech 17 (6) (2024)
   PUBMED   38511331
REFERENCE   2  (bases 1 to 6901)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 6901)
  AUTHORS   Cheng,L., Zhou,S., Zhou,S., Shi,K., Cheng,Y., Cai,M.C., Ye,K.,
            Lin,L., Zhang,Z., Jia,C., Xiang,H., Zang,J., Zhang,M., Yin,X.,
            Li,Y., Di,W., Zhuang,G. and Tan,L.
  TITLE     Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells
            in Ovarian Cancer
  JOURNAL   Cancer Res 82 (19), 3588-3602 (2022)
   PUBMED   35857807
  REMARK    GeneRIF: Dual Inhibition of CDK12/CDK13 Targets Both Tumor and
            Immune Cells in Ovarian Cancer.
REFERENCE   4  (bases 1 to 6901)
  AUTHORS   Campbell,G.J., Hands,E.L. and Van de Pette,M.
  TITLE     The Role of CDKs and CDKIs in Murine Development
  JOURNAL   Int J Mol Sci 21 (15), 5343 (2020)
   PUBMED   32731332
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6901)
  AUTHORS   Novakova,M., Hampl,M., Vrabel,D., Prochazka,J., Petrezselyova,S.,
            Prochazkova,M., Sedlacek,R., Kavkova,M., Zikmund,T., Kaiser,J.,
            Juan,H.C., Fann,M.J., Buchtova,M. and Kohoutek,J.
  TITLE     Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features
            and Intellectual Developmental Disorders as a Result of
            Non-functional CDK13
  JOURNAL   Front Cell Dev Biol 7, 155 (2019)
   PUBMED   31440507
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6901)
  AUTHORS   King,R., Struebing,F.L., Li,Y., Wang,J., Koch,A.A., Cooke
            Bailey,J.N., Gharahkhani,P., MacGregor,S., Allingham,R.R.,
            Hauser,M.A., Wiggs,J.L. and Geisert,E.E.
  CONSRTM   International Glaucoma Genetics Consortium; NEIGHBORHOOD Consortium
  TITLE     Genomic locus modulating corneal thickness in the mouse identifies
            POU6F2 as a potential risk of developing glaucoma
  JOURNAL   PLoS Genet 14 (1), e1007145 (2018)
   PUBMED   29370175
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6901)
  AUTHORS   Chen,H.R., Lin,G.T., Huang,C.K. and Fann,M.J.
  TITLE     Cdk12 and Cdk13 regulate axonal elongation through a common
            signaling pathway that modulates Cdk5 expression
  JOURNAL   Exp Neurol 261, 10-21 (2014)
   PUBMED   24999027
  REMARK    GeneRIF: The findings of this study suggest that Cdk12 and Cdk13
            regulate axonal elongation through a common signaling pathway that
            modulates Cdk5 expression.
REFERENCE   8  (bases 1 to 6901)
  AUTHORS   Dai,Q., Lei,T., Zhao,C., Zhong,J., Tang,Y.Z., Chen,B., Yang,J.,
            Li,C., Wang,S., Song,X., Li,L. and Li,Q.
  TITLE     Cyclin K-containing kinase complexes maintain self-renewal in
            murine embryonic stem cells
  JOURNAL   J Biol Chem 287 (30), 25344-25352 (2012)
   PUBMED   22547058
REFERENCE   9  (bases 1 to 6901)
  AUTHORS   Chen,H.H., Wong,Y.H., Geneviere,A.M. and Fann,M.J.
  TITLE     CDK13/CDC2L5 interacts with L-type cyclins and regulates
            alternative splicing
  JOURNAL   Biochem Biophys Res Commun 354 (3), 735-740 (2007)
   PUBMED   17261272
REFERENCE   10 (bases 1 to 6901)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154828.2 and AC154219.1.
            
            Transcript Variant: This variant (2) uses an alternate in-frame
            splice site in the 3' coding region, compared to variant 1. It
            encodes isoform 2 which is shorter than isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK173265.1, SRR11927934.2689921.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1660              AC154828.2         86643-88302         c
            1661-2317           AC154828.2         55506-56162         c
            2318-2488           AC154828.2         49641-49811         c
            2489-2628           AC154828.2         48159-48298         c
            2629-2799           AC154828.2         46309-46479         c
            2800-2989           AC154828.2         34876-35065         c
            2990-3046           AC154828.2         33462-33518         c
            3047-3148           AC154828.2         22296-22397         c
            3149-3226           AC154828.2         22122-22199         c
            3227-3343           AC154828.2         11272-11388         c
            3344-3475           AC154828.2         10325-10456         c
            3476-3681           AC154219.1         174599-174804       c
            3682-3951           AC154219.1         172867-173136       c
            3952-6901           AC154219.1         169473-172422       c
FEATURES             Location/Qualifiers
     source          1..6901
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 6.05 cM"
     gene            1..6901
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /note="cyclin dependent kinase 13"
                     /db_xref="GeneID:69562"
                     /db_xref="MGI:MGI:1916812"
     exon            1..1660
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..2317
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            2318..2488
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            2489..2628
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            2629..2799
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            2800..2989
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            2990..3046
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3047..3148
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3149..3226
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3227..3343
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3344..3475
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3476..3681
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3682..3951
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     exon            3952..6901
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5358..5363
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /note="hexamer: AATAAA"
     polyA_site      5381
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /note="major polyA site"
     regulatory      5395..5400
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /note="hexamer: TATAAA"
     polyA_site      5415
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
     regulatory      6540..6545
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /note="hexamer: ATTAAA"
     polyA_site      6562
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
     regulatory      6878..6883
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
                     /note="hexamer: ATTAAA"
     polyA_site      6901
                     /gene="Cdk13"
                     /gene_synonym="2310015O17Rik; Cdc2l5"
ORIGIN      
        1 cgccgccgcc gccacaggac gacgtggacg cgccgcggcc ggccggcgac ggaggcgtgc
       61 tgtggtcgcg cccactgccc tcccgcgagc tcgcccccga cgtcaggacg atggagtgaa
      121 gcgcggcccg cggtggcact tccgcgttgc gccgccggag cccgaggccg ccgccgccgc
      181 cgccaccgcc gccgcccggc acggccggct ttccgccgag gataggatcc tcccgcgcca
      241 ggccctgacg ccgctgcgca cacaccgcga ctggaaccgg ggacgcgcgt cccgacccgg
      301 attatcgtgg cgcgactccc ggccggccct gctgctcgct acccctccgc cgcggctgcc
      361 gtcccccttc ccggcggggg acatggccag ggtctgaccc cggaggaggc cgcacccgcg
      421 ccgcactctg cggcgggctc taggcgatgc cgagtagctc ggacacggcg ctggggggag
      481 gcgggggcct gagctgggcc gagaagaagt tggaggagcg ccgcaagcgg aggcgattcc
      541 tgtcccctca gcagccgccg ctgctgttgc cgctcctgca gccgcagctc ctgcaaccgc
      601 cgccgccccc gccgcctctg ctcttcctgg ctgcccccgg cgcggccgcc gccgcagccg
      661 ccgccgccgc ggcctcctcc tcttgcttca gcccgggccc tcctctggag gtcaagcggc
      721 tggcgagagg caagaggcgc cccggagggc ggcagaagcg gcgccgcggg ccccgcgccg
      781 ggcaggaggc ggagaagcgc cgggtcttct cgctgcccca gccgcagcag gacggcggtg
      841 gcggtgccag tagcggcggg ggtgtgaccc cgctggtgga gtacgaggat gtgagctccc
      901 agtccgagca ggggctgctg ctggggggcg ccagcgcggc aacggcggcg acggctgccg
      961 ggggaacggg gggcaacggc gggagtccgg cctcctcctc cggcacgcag aggcgcgcgg
     1021 aggggtcgga gcgcaggccg cgccgggacc gccgcagcag cagcggccgc agcaaggagc
     1081 gccaccgcga gcaccggcgg cgggacggga cgcgcagcgg cagcgaggcc tcaaaggccc
     1141 gcagccgcca cggacacagc ggcgaggagc gggcggaggc cgccaagagc ggcagcagca
     1201 gcagcagcgg cggccgccgc aagagcgcgt cggctacgtc cagcagcagt agcagccgca
     1261 aggaccggga cctcaaggcc caccgcagcc ggactaagtc gtccaaggaa ccgccctcgg
     1321 cctacaagga gccgcccaag gcctaccggg aggacaagag cgagccgaag gcctacaggc
     1381 ggcggcagcg gtccctgagc ccgctgggag gccgggacga aagcccggtg tcccacaggg
     1441 cctcgcagag ccttcggagc cgcaagtccc ccagtccggc gggaggtggc agcagtcctt
     1501 attcccggcg gctgccgcgc tccccgagcc cctatagccg gcgccgctcg cccagctaca
     1561 gccgccacag ctcctacgag cggggcggcg acgtatcccc cagcccgtac agcagcagca
     1621 gctggcggcg ctcgcgcagc ccctacagcc cagtactcag acgatctgcc aaatcccgaa
     1681 gcagaagccc atattcatct aggcactcaa gatctcggag caggcacaga ttgtctagat
     1741 caagaagtcg tcattcaagc atttctccta gcacactaac tctgaagagt agcttggcag
     1801 ctgaattgaa caagaataaa aaggcacgag ctgcagaggc agcaagagct gcagaggcag
     1861 caaaagctgc agaagctgct aaggctgctg aagcagctgc caaagctgcc aaagcctcaa
     1921 atgcttctac acctaccaag gggaacacag aaactggtgc cagtgtctca cagacaaacc
     1981 atgtgaagga agtcaaaaaa cttaaaactg agcatgcacc ttctccttca agtggtggga
     2041 ccgtcaaaag cgacaaagca aaaacaaagc caccgcttca agtaacaaag gtagacaata
     2101 atttgacagt agagaaagcc accaagaaaa cagttgttgg gaaggagagt aaacctgctg
     2161 ctacaaagga agaaccagtt tccactaaag agaaaagcaa gccactcaca ccaagcacag
     2221 gagccaagga gaaggagcag catgtggctt tagtgacctc tacgttaccg ccattacctt
     2281 tgcctcccat gctgcctgaa gataaagatg ctgatagctt aagaggcaac atttctgtca
     2341 aagcagttaa aaaagaagta gaaaagaaac tccgatgtct gcttgctgat ttaccattgc
     2401 cccctgagtt accaggagga gatgatcttt ccaagagtcc agaggagaag aaaacagcag
     2461 cacagttaca tagcaaacga aggcctaaaa tatgtgggcc tcgctatggt gaaatcaaag
     2521 aaaaagatat tgactggggg aaacgctgcg tggataaatt tgatatcatc ggaattattg
     2581 gagaaggtac ttatggacaa gtttacaaag ccagggacaa agacacggga gaaatggtag
     2641 ccttaaagaa agtacgtctg gataatgaaa aggagggttt cccaattaca gcaattagag
     2701 aaattaaaat tcttcggcaa ctcacccacc agagtatcat caatatgaag gaaatcgtga
     2761 ctgataaaga agatgctttg gattttaaga aagacaaagg tgcattttac ctggtgtttg
     2821 aatatatgga ccatgatctg atgggactgc tggaatcagg cttggttcat tttaatgaaa
     2881 accatataaa atcttttatg agacagctca tggaaggcct ggattattgt cataagaaga
     2941 actttttgca tagagatatt aaatgttcaa atatccttct aaataataga ggacagataa
     3001 aacttgcaga ttttggactt gctcgtttat atagctcaga agaaagtcgc ccatatacta
     3061 acaaggtcat tactttgtgg tatcgtccac ctgaattgct cttgggagaa gaacgatata
     3121 caccagccat tgatgtatgg agctgtggat gtatccttgg tgaactcttc actaaaaaac
     3181 ctatatttca agcaaaccag gaacttgcac agctagagct aataagccgt atatgtggga
     3241 gtccatgtcc tgcagtgtgg cctgatgtaa tcaaactgcc atatttcaac accatgaaac
     3301 caaagaagca atatcggcgg aagttaagag aagaatttgt tttcatcccc gcagctgcac
     3361 tcgacttatt cgattacatg cttgccttgg atcccagtaa gcgctgcact gctgagcagg
     3421 ctcttcagtg tgagttcctg cgagacgtgg aaccctccaa aatgcctcca ccagaccttc
     3481 ctttgtggca agattgtcat gaattatgga gtaaaaagag aagaagacag aaacagatgg
     3541 gcatgactga tgatctttcc acaatcaaag cccctaggaa ggacctgtct ctgggcttag
     3601 atgacagcag aactaacaca ccccagggtg tgctgccacc cgcacagttg aaatctcaga
     3661 gcaactcaaa tgtagcacct ggtgaaaaac agacagatcc atcaacacca caacaggagt
     3721 cttcaaaatc attgggagga gttcagcctt cacagaccat ccagcctaaa gtggaaactg
     3781 atgctgccca ggctgctgtg cagagtgcat ttgcagtcct cttgactcag ttaataaagg
     3841 cccaacagtc caaacagaaa gatgccatgc tagaggaaag ggaaaatgga tcaggacatg
     3901 aagctccatt gcaactcagg cctcctctag aaccgagcac tcctggatcc gggcaagatg
     3961 acctcatcca gcaccaagac aggaggatat tggagctgac accagaacca gaccggcctc
     4021 gaattctgcc tcctgatcaa cggcctcctg aacctcctga accaccacca gttactgagg
     4081 aggacctaga ttatcggaca gaaaaccagc atgttcctac cactagttct tcattaactg
     4141 acccacatgc tggagtgaag gcagccctct tacagctgct tgctcagcat cagccccagg
     4201 atgatcccaa aagagaaggt ggtatcgatt atcccacagg agacacatat gtgcccagtt
     4261 cagactataa ggacaacttt ggatcttctt tctctgccgc tccttacgtt agcagtgatg
     4321 gtctaggaag tagctccgct gctgcaccat tggaagcacg tagtttcatt ggaaactcag
     4381 atattcagtc tctggataac tacagtactg cttcatctca cactggtggt ccacctcaaa
     4441 cttctgcctt tactgagtcg tttgccagtt cagtagctgg atatggagac atttacctca
     4501 atgctggtcc catgttgttt agtggagaca aggaccatag atttgaatat agccatggtc
     4561 ctatcacagt cctcacaaac agcaatgacc cttccacagg gccagagagt actcatccct
     4621 tgccagcaaa gatgcacaac tataactatg gtggtaactt acaggaaaat ccaggtggcc
     4681 ctagcctcat gcatggacag acctggactt ctcctgccca aggacctgga tattcacaag
     4741 gatacagggg acacattagc acatcagctg gcagaggtcg aggcagaggg ttaccatact
     4801 gagtatctgt ttttcctcag gcacatcatt tttatctgga aagacttttc tagctgcaat
     4861 ttcaggcagc aatccaagag acttgaataa tattaattca acaacagctt tatttttatg
     4921 tggaaagggt cttgcataca atagtgaaaa aaacaaaaca acaaaaaaaa tctttgctta
     4981 aattcatgct gttcttaaaa ctagctctat tgattgtaca tcgtcacaga ttttagttaa
     5041 caattttatt ttgtattctt gcagttttaa gtggatgcta acattaggga cataatgttt
     5101 ttatggccct gtggcagatc ttctgaacta tgcacacttg tgcttttttt tgtaagtttg
     5161 gaccaacttt tatgtaaaca agctcccctt ccccccatgc cccccatccc ccttccagtt
     5221 ttacaacaat cagaaagggc actgatttat ttggtatttt ctttttacaa agctaccttt
     5281 agtcgaaggt cactgtcagt ctttgcacct gctttcagtg ttattgtgaa aggtgtactt
     5341 tgtgctcatt tcagaaaaat aaaacacaac ctttctcttg atgcaacagt tttatataaa
     5401 aaatggtcaa cattattttt gttttgtttt tttcaggtta ccataataca ggaaaattca
     5461 ttcaaatgaa atagtggttt ttatatgaaa actatgggta gggtggggag gggttgagta
     5521 agtgccttaa caggtaagct taaggtctgc ggatgaaatg agccttcaca ccactgtctt
     5581 tctaagggag tctgtactgt gctgacgggg cagggagctt ctccgctctc aggagttgct
     5641 tggtcagttc tgttagctcc attccctctg cctgcctgtc acactgtccc tttctgcctg
     5701 tcttttggct gtgttgactt ccactgttac cttctcttgg taggggtgta agaggaaaag
     5761 aaagggagaa ctcagaacct tatgttactt ctgggaagta ctaaaacttt tttttatcaa
     5821 ttaagtggtt gaaagtagta gctgaatgag aattttagag tgctcctttc tttctggctg
     5881 tcatactgac ccagtttcta tttggagggc aggagttttg aagcaagtat gtataacaat
     5941 tcataaataa atacatatgg tacataacaa atgtattgaa gtccacagaa ggagggtggc
     6001 aaacacctta ttttaagtta tataatttta agaaaatgtc aacttaagta gaaacatgtc
     6061 ctagatctaa tttagtaaag caaacagaaa actcaaagag aaaaccttcc ctcttccttt
     6121 caattctgtg aaatttacta taatttctgc cagattagag cagtgctatt ctattagaat
     6181 caaccaagaa agaataactc tgatgttgtc aagtcgcact atgtttacgt tcacacacac
     6241 acacacacac acacaaaaaa ccaaaattct atttctgaaa aggaaccaaa ggtaaatagc
     6301 cagcatcacc ttcatcattc gtagataaga gactctgggg aaccgccctc gcgtgccgac
     6361 tgacaatttc aattgttgta gtacctttcc cattggatac taagtaagga agaactgtta
     6421 tgaaaagcag cttagcttca tgccctttat atgatttgtg accctgcatt tacaaacatt
     6481 caggaaacat tattgtttgg tgacagaata ttttaaagat aattttccag tttatgccta
     6541 ttaaaaatga gttttcagtt gaccatttta ttttttgatc gtattttgtt ggtgaaagaa
     6601 aaaaattaat ggaagaaaaa atattttgct tttatttgaa tacagagtac taacaactta
     6661 ataaaacagt agaggaagtg aaaaaatgtt ttgaaattta gaaattagag tattcaagtc
     6721 tctgaaattt taatatggtg agtcttagag ctttagactt tcctataagt gacagtatct
     6781 aaattattat ttgtcacatt tggtacatct gctggccata agcagctaac ctaaaattga
     6841 aactatttat gtgacatgaa tagtctgtgt tttaaaaatt aaatatttta tataaaattg
     6901 a
//
