LOCUS       NM_001033364            4131 bp    mRNA    linear   ROD 06-DEC-2024
DEFINITION  Mus musculus cadherin-related family member 2 (Cdhr2), mRNA.
ACCESSION   NM_001033364 XM_193722 XM_484261 XM_891361 XM_916090
VERSION     NM_001033364.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4131)
  AUTHORS   Cencer,C.S., Robinson,K.L. and Tyska,M.J.
  TITLE     Loss of intermicrovillar adhesion factor CDHR2 impairs basolateral
            junctional complexes in transporting epithelia
  JOURNAL   Mol Biol Cell 35 (11), br21 (2024)
   PUBMED   39292922
  REMARK    GeneRIF: Loss of intermicrovillar adhesion factor CDHR2 impairs
            basolateral junctional complexes in transporting epithelia.
REFERENCE   2  (bases 1 to 4131)
  AUTHORS   Cencer,C.S., Silverman,J.B., Meenderink,L.M., Krystofiak,E.S.,
            Millis,B.A. and Tyska,M.J.
  TITLE     Adhesion-based capture stabilizes nascent microvilli at epithelial
            cell junctions
  JOURNAL   Dev Cell 58 (20), 2048-2062 (2023)
   PUBMED   37832537
REFERENCE   3  (bases 1 to 4131)
  AUTHORS   Pinette,J.A., Mao,S., Millis,B.A., Krystofiak,E.S., Faust,J.J. and
            Tyska,M.J.
  TITLE     Brush border protocadherin CDHR2 promotes the elongation and
            maximized packing of microvilli in vivo
  JOURNAL   Mol Biol Cell 30 (1), 108-118 (2019)
   PUBMED   30403560
  REMARK    GeneRIF: CDHR2 functions to elongate microvilli and maximize their
            numbers on the apical surface, which together serve to increase the
            functional capacity of enterocyte.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK144400.1, BC141301.1 and BX630481.1.
            
            On Dec 29, 2009 this sequence version replaced NM_001033364.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK144400.1, BC141301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849377, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-71                AK144400.1         2-72
            72-2213             BC141301.1         1-2142
            2214-4093           BC141301.1         2146-4025
            4094-4131           BX630481.1         1-38                c
FEATURES             Location/Qualifiers
     source          1..4131
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 29.03 cM"
     gene            1..4131
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /note="cadherin-related family member 2"
                     /db_xref="GeneID:268663"
                     /db_xref="MGI:MGI:2687323"
     exon            1..107
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            108..170
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            171..242
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            243..382
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            383..436
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            437..523
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            524..613
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            614..739
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            740..886
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            887..962
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1078
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1312
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1468
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1630
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1692
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            1693..1936
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2176
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            2177..2243
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            2244..2849
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            2850..2921
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            2922..2971
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            2972..3120
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3121..3229
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3230..3318
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3319..3387
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3388..3465
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3466..3526
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3527..3651
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3652..3765
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3766..3843
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3844..3901
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     exon            3902..4127
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4101..4106
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /note="hexamer: AATATA"
     polyA_site      4127
                     /gene="Cdhr2"
                     /gene_synonym="Gm624; PC-LKC; Pcdh24"
                     /note="major polyA site"
ORIGIN      
        1 gccggcccca gacggcgccc acctgtgact ggtgtacatc actgcctctg ggccccttcc
       61 aggggctgtc cagatcagct gcttctgggg gggctcttag cccgagggtc ccttcaagat
      121 ggcctggctg tggctgcttt gtgcactgct tcctgccttc atggtatctg tgacagccaa
      181 ctcgccacca tcatttgggg tcaatatgac attagtaacc ctgccagagg acttaccagt
      241 gggtgccgtg gccttctggt tggtggctac agacagtgat aatgaccacc tgacctatgg
      301 aatcagtggc ccaaacgcca gctacttctc cgtcaacgcg aacactgggg aagtgaagct
      361 tgccagccct ttggactttg agacagttcc tttcttcaag atcaccatct ccacaagtga
      421 tggtctcaac atcagaacag ccgagatgca agtgattgtg gaagacagaa atgataacat
      481 acctgttttc ctgaacactg aattctccac cagcatcaat gagaccctgc cagtcggttc
      541 tgtggtgttt tctgtgctgg cagaggacaa ggacacaggg acagccggtt tggtgcaata
      601 tttcatagag aaggtcatcc ccagcaccgc caacagcaat aatctcttcc gcatcctgga
      661 aaatggctcc attgtactga atgacacgct cagttacaac aacaagagtg ccttctacca
      721 gctggagctg aaggcctgtg actcaggggg aatattggat aacaagccaa aaacccaatg
      781 ctcccagccg gtcttcgtat ccatctcagt gattgatgag ccagacctgg accctcggtt
      841 tatcagggag ttctactcag cctctgtggc tgaggatgcc accttgggga cgtccgtgct
      901 gaccgtggag gctgtggaca gtgacaaagg catcaatgac attgtgacct acagtgtctc
      961 caactccacg aggcctgggt ggttcgacat cagggaagat ggggtcatct tcgtcaatgg
     1021 ctccctggac agagagcagc tgcttctgga aaacgaagaa gtgcagatac aggtcacggc
     1081 caccgagaag aatctgaaca tctacgggca agaggccaag gcaagcatgt gggtcacaat
     1141 aagggtgaca gatgtcaacg accacaagcc ggaattttac aactgcagcc tccctggctg
     1201 ctcctttagc ccccaggagg cccaagtcaa cttcataggc tacgtggacg agcatgcctc
     1261 tgcccgaatc tccatcgatg gtctgaccat ggtggcctat gatccagacc agggcgacaa
     1321 tggtaccttc ctgctgtccc tgaatggcca ggatgctgaa gccttcaatg tgtccccaga
     1381 gcgagcagca gggtctgtca gtgtgcaggt ggtggtgaga aactcagaga tggtggacta
     1441 tgagaaggag acagtgatgg ttgtggaggt tgtggccact gactcagtca gcaacaacta
     1501 ctctgttgcc acggtgacca tccaccttag aaacatcaat gaccacaggc ctgtgttctc
     1561 tcagagcctg tatgaactca ctgtgccaga gcactgtcca acaggttatc tggtcactga
     1621 caaaatccag gctacagacc tggatgggga tgaatggggt cctatcacct acagtctgct
     1681 tccaggaaat ggagctgacc tgtttgaggt ggagccaaac tcagggaatc tgacggtgaa
     1741 aaatggcacg ctgctggacc gagagaagca ggctgtgtac tacctcacgc tgcaggccac
     1801 tgacggtggc aaccagtcga ccaccaccgc cctggagatc actctgctgg atatcaatga
     1861 caacccgcct gtggtccgag gctcctataa cgtcttcgtg ccggaggaga atggcaatgt
     1921 ctctgtgacc atccaggcct atgatgatga ccagccagac actaacaaca gcctcctggt
     1981 cttcagcctg cttcctgggc cctacagcag caacttctcc ttagacccca acacagggct
     2041 cctcaggaat cttgggcccc tggaccgaga ggccattgac cctgccctgg agggacgcat
     2101 cgtgctaact gtgattgtgg ctgactgcgg cgagccttcc ctgagcacta atgtcaatgt
     2161 caccatcacg gtagaggaca tcaatgacaa cctgcctgtc ttcaaccagt cttatgaatt
     2221 ctctgtgtgg gagagagttc caggagcatg ggtgggcaca gtgaaggcct gggatgctga
     2281 ccagacggca gccaacaacc gcatcagctt cagcttgtct gggactggcg ccaacaattt
     2341 tatcctccaa ggcaacgtgc tggaacaagg gtgggcagag ggtagcctct ggctgctccc
     2401 ggatgtgaga ctggattacg agacacagaa gttcttccac ctgacagtga gtgctgagaa
     2461 cccaggcccc cagggcctcg attctacagc caatgtcacc gtcacggtga tggatgtgaa
     2521 tgatgagccg cccaccctgg atgcagcctc actccaggcc atctctgtga ctgagaatgg
     2581 ctctgagcat ggccaggtga ctcgggtgat agcccaggat gtggatactg ctgcgttgct
     2641 gaggatagag ctggtggacg tcatctgcac caaggctggg gttgacgtgg gcagcgtgtg
     2701 tcacggctgg ttctctgtgg atggcaacgg ctctgtgtac atcaatcaga gtgaggccat
     2761 cgactatgag gcttgtcacc tggtcacgct ggtcgtgcgg gcgtatgacc tcaacacgga
     2821 tccgggcttt gatgcttaca gcagcaatgg aagccttctc atcaacatca aggacaagaa
     2881 tgacaatgcc ccctattttc tgcctaacaa ccagaccttc gtgatcatcc cagagcttgt
     2941 gttgcccaac cagcaggtgg cttctgtcca ggccagagat gaggactcag aagacaatgg
     3001 gatcatcatg ttctccatcc tgaaagcaga atttgtccgc aaagatggaa cttccaaccc
     3061 tgtccaggtc ttccggatta ccagatcagt ggaagctggc ctgttcactg gcagcatcga
     3121 gttggtgacc aacctagatt ctactatcca aggcacatac caggtgacag ttcaggccca
     3181 agatcagccc acattgggtc ctgccctaga gacacagacc actctgaatc tcttcactgt
     3241 ggaccagagt taccgtgtga ggctgcagtt ctccaccagc aaggaggatg ttggtgccaa
     3301 tatggaggag atcaaggagg ctcttatcca ggcgaccaga acctctgtct acgttgtgac
     3361 catccagaac atagactcta cggctcgggc ccgagccagc tcctacatgg acgcctactt
     3421 tgtcttttcc aatgggacag ccctgacact cactgagctg aatatgatga tccggaaaga
     3481 ccaggatgca ctgaggcagc tgctgcaact ggggctggtg gtggtgagct cccaggagag
     3541 ccaggagccc gatcagcaga aactgctcac cagtgtcatc ataggactgg tggtgtcttt
     3601 ggtgctggtc cttgtgattt tgattacggc ccttgtgtgt ttgcggaaga gctatcaccg
     3661 gaagcttcga gctatgaagg ctggcaagga ggcccgaaag acaccaatag agacgacagc
     3721 tccaactgct gctatcccag ggactaacat gtacaatact gatcgggcca accccgtgct
     3781 ggacctcccc accaaggatc tgggcttgga gtgccactcc tccagtgact tggactatga
     3841 cagcctcaat tccctagatg agaactctgt ggacttggac atggacagta aggaattcaa
     3901 gaggaaggat cttccaggag accctcctga gcctgaccct gagcccctga ctgcagtgct
     3961 ctcaggaagg tcggcaggtg cgagcgaaca gcagaaaaag aatctgtcct tcaccaaccc
     4021 tggcctggac accacagatc tgtgacggag cctgtcattc ttcgagctca aaccgtactg
     4081 tctgccctcc cctaaaatat aatatatggc cttgcttgtc aatcataaaa a
//
