LOCUS       NM_007666               8185 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus cadherin 6 (Cdh6), mRNA.
ACCESSION   NM_007666
VERSION     NM_007666.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8185)
  AUTHORS   Bessa,P., Newman,A.G., Yan,K., Schaub,T., Dannenberg,R., Lajko,D.,
            Eilenberger,J., Brunet,T., Textoris-Taube,K., Kemmler,E., Deng,P.,
            Banerjee,P., Ravindran,E., Preissner,R., Rosario,M. and
            Tarabykin,V.
  TITLE     Semaphorin heterodimerization in cis regulates membrane targeting
            and neocortical wiring
  JOURNAL   Nat Commun 15 (1), 7059 (2024)
   PUBMED   39152101
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8185)
  AUTHORS   Song,L., Li,Q., Xia,L., Sahay,A.E., Qiu,Q., Li,Y., Li,H.,
            Sasaki,K., Susztak,K., Wu,H. and Wan,L.
  TITLE     Single-cell multiomics reveals ENL mutation perturbs kidney
            developmental trajectory by rewiring gene regulatory landscape
  JOURNAL   Nat Commun 15 (1), 5937 (2024)
   PUBMED   39009564
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8185)
  AUTHORS   Lin,F., Li,Y., Wang,J., Jardines,S., King,R., Chrenek,M.A.,
            Wiggs,J.L., Boatright,J.H. and Geisert,E.E.
  TITLE     POU6F2, a risk factor for glaucoma, myopia and dyslexia, labels
            specific populations of retinal ganglion cells
  JOURNAL   Sci Rep 14 (1), 10096 (2024)
   PUBMED   38698014
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8185)
  AUTHORS   Sinclair-Wilson,A., Lawrence,A., Ferezou,I., Cartonnet,H.,
            Mailhes,C., Garel,S. and Lokmane,L.
  TITLE     Plasticity of thalamocortical axons is regulated by serotonin
            levels modulated by preterm birth
  JOURNAL   Proc Natl Acad Sci U S A 120 (33), e2301644120 (2023)
   PUBMED   37549297
REFERENCE   5  (bases 1 to 8185)
  AUTHORS   Escuin,S., Rose Raza-Knight,S., Savery,D., Gaston-Massuet,C.,
            Galea,G.L., Greene,N.D.E. and Copp,A.J.
  TITLE     Dual mechanism underlying failure of neural tube closure in the
            Zic2 mutant mouse
  JOURNAL   Dis Model Mech 16 (3) (2023)
   PUBMED   36916392
REFERENCE   6  (bases 1 to 8185)
  AUTHORS   Ikeya,M., Lee,S.M., Johnson,J.E., McMahon,A.P. and Takada,S.
  TITLE     Wnt signalling required for expansion of neural crest and CNS
            progenitors
  JOURNAL   Nature 389 (6654), 966-970 (1997)
   PUBMED   9353119
REFERENCE   7  (bases 1 to 8185)
  AUTHORS   Inoue,T., Chisaka,O., Matsunami,H. and Takeichi,M.
  TITLE     Cadherin-6 expression transiently delineates specific rhombomeres,
            other neural tube subdivisions, and neural crest subpopulations in
            mouse embryos
  JOURNAL   Dev Biol 183 (2), 183-194 (1997)
   PUBMED   9126293
REFERENCE   8  (bases 1 to 8185)
  AUTHORS   Lechner,M.S. and Dressler,G.R.
  TITLE     The molecular basis of embryonic kidney development
  JOURNAL   Mech Dev 62 (2), 105-120 (1997)
   PUBMED   9152004
  REMARK    Review article
REFERENCE   9  (bases 1 to 8185)
  AUTHORS   Munro,S.B. and Blaschuk,O.W.
  TITLE     A comprehensive survey of the cadherins expressed in the testes of
            fetal, immature, and adult mice utilizing the polymerase chain
            reaction
  JOURNAL   Biol Reprod 55 (4), 822-827 (1996)
   PUBMED   8879495
REFERENCE   10 (bases 1 to 8185)
  AUTHORS   Munro,S.B., Duclos,A.J., Jackson,A.R., Baines,M.G. and
            Blaschuk,O.W.
  TITLE     Characterization of cadherins expressed by murine thymocytes
  JOURNAL   Cell Immunol 169 (2), 309-312 (1996)
   PUBMED   8620560
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK134611.1, CN531307.1,
            AC139574.4 and BI134319.1.
            
            On Oct 24, 2015 this sequence version replaced NM_007666.3.
            
            Summary: This gene encodes a member of the cadherin family of
            calcium-dependent glycoproteins that mediate cell adhesion and
            regulate many morphogenetic events during development. The encoded
            preproprotein is further processed to generate a mature protein.
            Mice lacking the encoded protein exhibit delay in
            mesenchyme-to-epithelial conversion and a loss of nephrons.
            Multiple distinct genes of the cadherin family, including this
            gene, are found on chromosome 15. [provided by RefSeq, Oct 2015].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219381.126252.1,
                                           SRR7974084.3913.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-938               AK134611.1         2-939
            939-1166            CN531307.1         439-666
            1167-1167           AC139574.4         102381-102381
            1168-1264           CN531307.1         668-764
            1265-1294           AC139574.4         102479-102508
            1295-1548           AC139574.4         104759-105012
            1549-1685           AC139574.4         111524-111660
            1686-1807           AC139574.4         113625-113746
            1808-1925           AC139574.4         114841-114958
            1926-2177           AC139574.4         115096-115347
            2178-7729           AC139574.4         121615-127166
            7730-8185           BI134319.1         1-456               c
FEATURES             Location/Qualifiers
     source          1..8185
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 6.11 cM"
     gene            1..8185
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /note="cadherin 6"
                     /db_xref="GeneID:12563"
                     /db_xref="MGI:MGI:107435"
     exon            1..162
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            163..523
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     CDS             296..2668
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /note="kidney cadherin; K-cadherin"
                     /codon_start=1
                     /product="cadherin-6 preproprotein"
                     /protein_id="NP_031692.2"
                     /db_xref="CCDS:CCDS27393.1"
                     /db_xref="GeneID:12563"
                     /db_xref="MGI:MGI:107435"
                     /translation="MRTYRYFLLLFWVGQPYPTFSNPLSKRTSGFPAKRKALELSANS
                     RNELSRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFI
                     INENTGDIQATKRLDREEKPVYILRAQAVNRRTGRPVEPESEFIIKIHDINDNEPIFT
                     KDVYTATVPEMADVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIK
                     TALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFK
                     TPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGHEMFDVITDQETQEGIITVKKL
                     LDFEKKKVYTLKVEASNPHVEPRFLYLGPFKDSATVRIVVDDVDEPPVFSKLAYILQI
                     REDARINTTIGSVAAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRET
                     LLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQT
                     LRAVDKDDPYSGHQFSFSLAPEAASSSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLL
                     PVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVAILLCIV
                     ILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGEEDTQAFDIGTLRNPEA
                     MEDSKSRRDIVPEALFLPRRTPTARDNTDVRDFINQRLKENDTDPTAPPYDSLATYAY
                     EGTGSVADSLSSLESVTTDGDQDYDYLSDWGPRFKKLADMYGGMDSDKDS"
     exon            524..818
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            819..938
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1106
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1294
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1548
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1685
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1807
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1925
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..2177
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..8169
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8150..8155
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /note="hexamer: AATAAA"
     polyA_site      8169
                     /gene="Cdh6"
                     /gene_synonym="cad6"
                     /note="major polyA site"
ORIGIN      
        1 gtgtgcccac aagagccagc tctctggagc cgtaaccttc ccatcccgag agctgcagtt
       61 ccagccacag cagcaagaag cacagagcag aagaccgtgg tggaggcagg agcatcctgg
      121 gcgagtggca gggtgtcccc aggagccgga aggcaaaccg aggtaccctc tgaaagccaa
      181 gcaaagaaca ttaaggaagg aaggaggaat gagcctggat ttggtgcagt gaaaagaggc
      241 gtattaagaa aaggggagct cacacccaga ctcgactgcc tgccttgcca gcatcatgag
      301 aacttaccgg tacttcttgc tgctcttttg ggtcggccag ccctacccaa ctttctcaaa
      361 cccattatct aaaaggacta gtggcttccc agcaaagagg aaagccctgg agctctctgc
      421 aaacagcagg aatgagctga gccgttcgaa aaggagttgg atgtggaatc agttcttcct
      481 cctggaggaa tacacgggat ccgattatca gtacgtgggc aagttacatt cagaccagga
      541 tagaggagat ggatcactta aatatatcct ttcaggagat ggagcgggcg atctcttcat
      601 tatcaatgag aacacaggcg acatacaggc caccaagagg ctggacaggg aagaaaaacc
      661 tgtttacatc cttcgagctc aagctgtcaa cagaaggaca gggagacccg tcgagcctga
      721 gtctgaattc atcatcaaga tccacgacat caatgacaat gagccaatat tcaccaagga
      781 cgtttacaca gccacagtcc cggagatggc tgatgttggc acatttgtgg tccaagtcac
      841 ggcgactgat gctgacgacc caacatatgg gaacagtgct aaagtcgtct atagcatcct
      901 gcagggacag ccctactttt cagtggaatc ggaaacaggt atcatcaaga cagcgttgct
      961 caacatggat cgagaaaaca gagaacagta ccaagtggtg attcaggcca aggacatggg
     1021 cggccagatg ggaggactgt cggggactac gaccgtgaac atcacgctga cagatgtcaa
     1081 tgacaaccca ccccgtttcc cccagagtac ctaccagttt aagacccccg agtcctctcc
     1141 accgggaacg ccaattggca ggatcaaagc cagtgatgcc gatgtgggag aaaatgcgga
     1201 gatcgagtac agcatcactg acggtgaggg acacgagatg tttgatgtca tcaccgacca
     1261 ggaaacccag gaagggatca taactgtcaa aaagctcttg gattttgaga agaagaaggt
     1321 gtacaccctc aaggtggaag cctccaatcc ccacgtcgaa ccccgatttc tctacctggg
     1381 tcccttcaaa gactcggcca cggtgagaat cgtggtggac gatgtggacg aacctcctgt
     1441 cttcagcaaa ctggcctaca tcctacagat acgggaggat gcccggataa atacgaccat
     1501 aggctctgtc gcagctcagg atcctgacgc tgccaggaat cctgtcaagt attctgtgga
     1561 tagacacaca gatatggaca ggatattcaa cattgattct ggaaatggtt cgatttttac
     1621 atcaaaactt ctcgaccggg aaaccctgct gtggcacaac atcacagtga tcgcaacgga
     1681 gattaataac ccaaagcaaa gcagccgcgt tcctctatat attaaagttc tcgacgtcaa
     1741 cgacaatgcc ccagagtttg ctgagttcta tgaaactttt gtctgtgaaa aagcaaaggc
     1801 agatcagctg attcagaccc tgcgtgctgt tgacaaggat gatccttaca gcggacacca
     1861 attttccttc tccttggccc cagaagcagc cagcagctca aactttacta tacaagacaa
     1921 caaagacaac actgcaggga tcctaactcg gaaaaatggc tataacagac acgagatgag
     1981 cacctatctc ctgcctgtgg tcatttcgga caacgactac ccagtccaaa gcagcactgg
     2041 gacagtgact gtccgggtct gtgcatgtga ccaccatggg aacatgcagt cctgccacgc
     2101 cgaggccctc atccacccca cagggctgag cacaggggct ctggtggcca tccttctgtg
     2161 catcgtgatc ctactagtga cagtggtgct gttcgcagct ctgaggcggc agcgaaagaa
     2221 agagcctttg atcatttcca aagaggacat cagagataac attgtcagtt acaacgacga
     2281 aggtggcgga gaggaagaca cccaggcctt tgatatcgga accctgagga accctgaagc
     2341 catggaggac agcaaatcgc gcagggacat tgtgcctgaa gctctttttc taccccggcg
     2401 gactccaaca gctcgtgaca acacggatgt cagagatttc attaaccaaa ggttaaagga
     2461 aaatgacacg gacccaacag cccctcctta cgactccttg gccacctatg cctacgaagg
     2521 caccggctct gtggccgact ccctgagctc gctggaatcc gtgaccacgg atggagatca
     2581 agattatgac tatttgagtg actggggccc tcggttcaaa aagctggcag atatgtatgg
     2641 agggatggac agtgacaaag actcctaatc tgttgccttt ttcattttcc aatatgacac
     2701 tggactgtgt gacgtggcta gtcctttcta tttatccact attccgtgag gggttctccc
     2761 gttgtacctg gtccaaaagt caatggctgc agtccgtgtg gatccaatgg tagagacttt
     2821 tttctagtac acttttatga gcttccaaga ggcaaatttt tattttttag ttcatgcagt
     2881 taaccaagtt agcccagcag acacgcggag ggaggagagg taggaacggc ccttgtcccc
     2941 ttagagccgg tcggccacat cccttactgc tggcctagac tctactactt ccttcatggc
     3001 ctccagtcag ctgaatgttc ctactgtaca tttcacatgc taatggaaga agggatcatt
     3061 ttaatgatag aaatatagtt ttagcattta aaaagggggg taacaattgg gaaattgttc
     3121 ctggtctatc agctctcaag gagataatta actttggagc ggtttgtaag gatgtgtgtg
     3181 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtcaaggaa ttaaagtggt
     3241 atctggggca tcctgtctgt gctgggaaag gtgttcctag caccaacaac cacccataac
     3301 gtcaaatcct tccgtgtttt aagatgattt aggagcaaat caaatggtat cgttcaaaga
     3361 cagtgatgaa agacgaaggt gtgttccctg acacgatttg gttgcatgtg ataaacatag
     3421 aaggttcacc atcacaccaa accaagggaa gaagagaaat agctttacaa aaaaaaaaaa
     3481 aaaaaaaaaa aaaaaaaagt taacaaaggg aatcagggaa atttagggaa tttcaaggtt
     3541 ttgtgccatc aagtatctcg gttcccttca ttctttcaac tatcaggaat ctaatgagaa
     3601 gtaggtctaa tactataaat gtcctagaga gaatttcctg aggcaaatgt taactctttg
     3661 tagttgtggt tgctattatc ctcctgtacc tgagtataga agtgtgaagt acaataattc
     3721 atattcttca aatacttctt ttatataatt aacctgactt agtgcggctt agtagattga
     3781 ataccccacc ctagagctca aggggaaggt gagagccagt cacatttgaa cctaacccct
     3841 gccctttgac ctcggagcca tccctacact gcagcaaggg aaagaaatga ctagcactga
     3901 gatgttggtg gaagccagca ttccctgctc ctacaaggct cacagaagaa gagcatggat
     3961 ccccttcagc aagaatgctt aagactcgtg tcacagggac agtcgatttc caaacacagc
     4021 catgctttcc caactggctt cggtagcaac actaccatcc ttgtctttga aatgatgata
     4081 aagtaatagt ctcaactatg agagaaaagt aatataaaat ccatacaatc tattattgct
     4141 ctaattatgc agttaggctc tcttagtcag ttattatcca ggggacccaa ctgaacccag
     4201 ttaatccttc tggcaggttc aaatcattta tttcatatga ccgttctaat gactctcccc
     4261 attagattct catagtgtgc agtcatcaga aatttccaaa gtactgtaat gaaaacatcc
     4321 tcatttgaaa actttaaaaa aaaaaggctc tgtacataca tatataatat atacttaaga
     4381 atgtgctgat ttctcttaat agtcatagga atttattttc aattaatgtt cattttatag
     4441 agataatctt agtatcatct ccatttcagg gtgaggtttt atcaacacat tttctgtgta
     4501 gaaacacact attgtttagt tgacttttaa ataggtgtgt tacccaggtg taaaggtggc
     4561 acctgtggaa cgggagaact gcggaatttg gaatacagtt taaaaaaaaa aatatatata
     4621 tatatatata tatatttaca accacattgc cctttgtatt tcctgaatgg tttcctgttt
     4681 gtgatgggat atcccgaata gtgatgagta tttcatgctt aggctatttc cagcttttag
     4741 gttttatttt tctaattctt catacacaca cacatacaca cacacaggaa cacaaacaaa
     4801 tgctacaagg tggcttcact gaatgtattc cattcgcagg taagtaatga aaaaagatag
     4861 ccaaggaaga ttaataagag ttactaagaa tcacaagaac tgcactttac acagtttatt
     4921 gtaaaattag aatgctctat cttatatctt acattatgtg acaaattgaa ccaagaaaca
     4981 tagttcttaa aaagaaaggt attatctaaa gttgcccttt tgagcttctg gtgtgaagtt
     5041 tggtgttaaa tttccaaggg ctgacaagag caatttccaa ccttttggga taaagttgac
     5101 ctctcctctg agtgcaagtg ttccttgaaa ggaagttgag ttgtctgcca ggtaattggt
     5161 caaagttttt ttttaatctc accctgaaaa atcacacatc ataccaagaa tagatgacta
     5221 tgactcaata ttgaaataac tatttattgt cttatcgcaa agattgttgg ggaagcaaat
     5281 ctgcaaagaa actgaactat ttgagtcctg taggtgtcaa gttcagagaa actcttgcct
     5341 ctaagaatca tcacacagca aatgggaact ccaacttcat ctctctctga atttctgctt
     5401 cccaccaaaa taccaggtta agaacatccc cacggacaga tttctttgag ggatgagtcc
     5461 tgagccaact tgaaatgccg ttctgggggg gagggggaga acacagtttt cagcccactt
     5521 ttcatattat ctgtatcttg atctacagac acaggcaatg agaatgacaa gagagcagga
     5581 ggggtccaac tttagcattt gctttgttga acataagcag actgggtagt aatacaaggt
     5641 tgtttcaaga gcactgatgc ctgtctaact ttaaacctct tttcatcaga aagagggtct
     5701 ttaaacttct tatgatgctt cctagaataa gctgagattt taaagaacat tgagccattg
     5761 tgcattaggt taaaattccc tcactatctg ctttcttcag aaaaatctga aaacatttgt
     5821 cctcaaataa gtaaataaat caatttggaa agatgtgcag accatttcat gagaccctag
     5881 gagtggaaat ctgggcaatg taaatacgac ttccctactt tcacattctg gaggttcagc
     5941 tagagagtca ctctattttc agatggaaca aagctggtga tttcatttta attcaggata
     6001 aaaatatgtg gcttagttct catttccact cctcaaagtg ttattataca agaaactgac
     6061 tctggatctc agaagagcca agttttgaga agccaaaata acttgttaat gtttccatta
     6121 tgtaatctgt gtgtctcatg aacaatattc tatgtagaat gctttatcgt ggaagcaggt
     6181 atttcctaga ggaaaaggat ttataaaata tcaacaaggc attctgagat tctgcagcct
     6241 tgagcaccat agaaacataa cagcaaaaaa gaaaaaaaca gttgattcct aggtgcaagc
     6301 taaatatttg aatgaggtgc ttattctaat caaataaatg ccttttcttt tacagccacc
     6361 aaataaattc tcttagcccc caaatactat gtttgaagta gcataacaac tttggaaaac
     6421 cactctaaga agtaaaaata tctgctattt taaaagacag gctccatttt gtttttaaaa
     6481 aaatcatttt gctgtaattt tattttttac tctatttaga tgaaattatt tttgaattgt
     6541 tacattgtag aagggggggc aggatacagg cagtttactg tatttaaact aacactccac
     6601 ccaaccttct ttctcagatt atacgggcag aaagattaat aactagtgtg gccattttca
     6661 ggacgatggg ttgcatcctg agttctgaca agcgtgtttt ctttgccaga gagtggaatt
     6721 acattgtggt ctcctcagag ttcagtgacg atcatggttg cagagtttta aatcttcctt
     6781 tgacatcttt acagaataat tttcaaaagg ggtaattctc tactgaaaat accagaccct
     6841 gacaatattt aatgcaaaga gcaataccct gttaggaagc aaatacatcg gctcacagac
     6901 ttgttaaaac ttaataaaga aatagctcat ttttaaagcc aggagtttat ggtctctgca
     6961 tcatcgattt aatttaagca ttgctgagac aatctttaat ctccccattt tgtaatacct
     7021 tatttatggt gcattctcat tttttaattt ggggggaacg ttagcctgcc agagccacca
     7081 gatgaaagtg ttaagaggag gtcaaacgga aacaaaggcc attacccgcc atatttcaga
     7141 caagactagg gcacttagcc gaggagacac ccggttatta gattaatttc aaaagacctt
     7201 ttacaagttg cttaattccc ttaaaagaaa aagaagaaga agaaaaccct tggaccacaa
     7261 actcaaatgt cctttcacat gaggttattt gacaaatgag aaatggactc agtgttgtag
     7321 aaaaagcagc cctctgtaat gagatcttgg tctttcgtgt gaggctaatg ctacttatgt
     7381 aaatatatct ggagcacctt ctgtaagctt ttagttttct atgatctatt agtttagtgt
     7441 ttattataaa ataaaataaa aaacccatat gtagaatcac tcggcactca cggggaatgc
     7501 ttgtacaaca aacgtccaat agatctgctc agaagaaacg caggaacact tcaaacccac
     7561 tgtgctgttc tgtttgcaat tattcttact gctttgaaag gaagccgcat cagaataggc
     7621 cttgtaataa gcgctgtgtg cgtcttctct aataccaagc taaggccgtt tgggttctcc
     7681 tactgtgact tgtgatttct aaaccaagaa aataaaggct ttctggtgat ctactgtagt
     7741 tacttaaaaa ataattcaag tataaactga agcttatgcc accctttgaa gacctactgg
     7801 ccggagtcca ctatccgttc gtgtcttcag caagatgaac gaacggagga tggaaacaat
     7861 tgggctggct tctatccttg cgcctagttc ggcagcttgc tgtagcctta cgtattacgt
     7921 ggcaaagttt tctgtgtttg gagaatgagg tagctcagtg tggctgggcc ctctgttgta
     7981 gtcaaatgag agataacacc actccttgac atggcttctt ttagttggtt ttcttttctt
     8041 agtcttataa atttgaaaag gatgcaactt taaaaaagtg atttctcaca aagagtaaat
     8101 atgccttttg caaatcaatt tttgtaacgt tatttatatg atattactta ataaactgtt
     8161 tttttctaaa aaaaaaaaaa aaaaa
//
