LOCUS       NM_198656               3028 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus cadherin-like 26 (Cdh26), transcript variant 1, mRNA.
ACCESSION   NM_198656 XM_355371
VERSION     NM_198656.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3028)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3028)
  AUTHORS   Liu,T., Sun,Y., Guo,Z. and Bai,W.
  TITLE     Knockdown of Cadherin 26 Prevents the Inflammatory Responses of
            Allergic Rhinitis
  JOURNAL   Laryngoscope 133 (7), 1558-1567 (2023)
   PUBMED   36069256
  REMARK    GeneRIF: Knockdown of Cadherin 26 Prevents the Inflammatory
            Responses of Allergic Rhinitis.
REFERENCE   3  (bases 1 to 3028)
  AUTHORS   Feng,Y., Chen,S., Xiong,L., Chang,C., Wu,W., Chen,D., Gao,J.,
            Chen,G., Yi,L. and Zhen,G.
  TITLE     Cadherin-26 Amplifies Airway Epithelial IL-4 Receptor Signaling in
            Asthma
  JOURNAL   Am J Respir Cell Mol Biol 67 (5), 539-549 (2022)
   PUBMED   35930423
  REMARK    GeneRIF: Cadherin-26 Amplifies Airway Epithelial IL-4 Receptor
            Signaling in Asthma.
REFERENCE   4  (bases 1 to 3028)
  AUTHORS   Desgrange,A., Heliot,C., Skovorodkin,I., Akram,S.U., Heikkila,J.,
            Ronkainen,V.P., Miinalainen,I., Vainio,S.J. and Cereghini,S.
  TITLE     HNF1B controls epithelial organization and cell polarity during
            ureteric bud branching and collecting duct morphogenesis
  JOURNAL   Development 144 (24), 4704-4719 (2017)
   PUBMED   29158444
REFERENCE   5  (bases 1 to 3028)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 3028)
  AUTHORS   Lun,M.P., Johnson,M.B., Broadbelt,K.G., Watanabe,M., Kang,Y.J.,
            Chau,K.F., Springel,M.W., Malesz,A., Sousa,A.M., Pletikos,M.,
            Adelita,T., Calicchio,M.L., Zhang,Y., Holtzman,M.J., Lidov,H.G.,
            Sestan,N., Steen,H., Monuki,E.S. and Lehtinen,M.K.
  TITLE     Spatially heterogeneous choroid plexus transcriptomes encode
            positional identity and contribute to regional CSF production
  JOURNAL   J Neurosci 35 (12), 4903-4916 (2015)
   PUBMED   25810521
  REMARK    Erratum:[J Neurosci. 2015 Jun 3;35(22):8686. Adelita, Tai
            [corrected to Adelita, Tais]]
REFERENCE   7  (bases 1 to 3028)
  AUTHORS   Duan,X., Krishnaswamy,A., De la Huerta,I. and Sanes,J.R.
  TITLE     Type II cadherins guide assembly of a direction-selective retinal
            circuit
  JOURNAL   Cell 158 (4), 793-807 (2014)
   PUBMED   25126785
REFERENCE   8  (bases 1 to 3028)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL772217.10, AL935120.9 and AL773557.21.
            
            On Nov 4, 2022 this sequence version replaced NM_198656.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC053928.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               AL772217.10        189004-189372
            370-474             AL772217.10        199927-200031
            475-636             AL935120.9         8273-8434
            637-784             AL935120.9         15895-16042
            785-951             AL935120.9         18523-18689
            952-1080            AL935120.9         19142-19270
            1081-1266           AL935120.9         21053-21238
            1267-1535           AL773557.21        3183-3451
            1536-1678           AL773557.21        4757-4899
            1679-1924           AL773557.21        6633-6878
            1925-2140           AL773557.21        8208-8423
            2141-2271           AL773557.21        8946-9076
            2272-2328           AL773557.21        14267-14323
            2329-2406           AL773557.21        18244-18321
            2407-3028           AL773557.21        23369-23990
FEATURES             Location/Qualifiers
     source          1..3028
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 99.94 cM"
     gene            1..3028
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /note="cadherin-like 26"
                     /db_xref="GeneID:381409"
                     /db_xref="MGI:MGI:2685856"
     exon            1..369
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     CDS             319..2610
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; cadherin-like protein 26"
                     /codon_start=1
                     /product="cadherin-like protein 26 isoform a precursor"
                     /protein_id="NP_941058.1"
                     /db_xref="CCDS:CCDS17162.1"
                     /db_xref="GeneID:381409"
                     /db_xref="MGI:MGI:2685856"
                     /translation="MDTRGCAWLLLLLSLPQGQSHQPLHRSKRRWVLTTLELQEEDPG
                     PFPKLVGELFNNMSNNVSLIYLIRGPGVDEFPEIGLFSIEDHQSGKIYVHRPVDREVT
                     PSFMVHFDAVDRSTGKVVDESLIFNIRIRDVNDHAPQFPEKEFNISVKESQAAGQPIF
                     QLLTVDLDQENTPNSQVLYFLVSQTPLLRESGFRIDLISGEVRLSGCLHYETAPLFTL
                     IVRASDCGEPSLTSTATIHVSVEDSNNHMPTFMEDRYEIRISEGQVEQGVLYLPVQDG
                     DSPFTPAWRTQFNIWDGNEEGHFDIVTDPETNQGLLSIIKPLDYESQVAHSLVVVVEN
                     QEQLFVCTEGQLQPLRKAMASTMVSVQVLDTNDPPAFHPQSFIVSEEDGAWPAIQLGY
                     FNATDPDRADSQIRYKLVHDPENWVTVDEKSGVVTTKKQIDRESPHVNDSFYTIIVHA
                     VDNGLPPLTGTGTLMLFLSDVNDNAPTLRPHSRHLEVCESAGSQPLLIEAEDADLDPY
                     ADPFTFDLDNAQGDVEETWMLRTKQGEGHSAELTMLRSVPPGDYLVPLFIADRQGLAQ
                     KQTVHVRICSCRSGSECEEPSDTWLLWWALSPVGAALMVLSAALLCLLRCSCTFGPKR
                     LRGFIPSDSGHQTLIVYNEESKVPSAQGCDTFFEPRGVKTLLSSTPVYLDRMVPRQQP
                     LQLLEGRVVEAWSQKLQSIDVLEGDTGYLPHVYREEGECEGAETLSSLTFLEQDLSPK
                     LLGCSGSKSTPSEAMCFTSRVPS"
     exon            370..474
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            475..636
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            637..784
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            785..951
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            952..1080
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1266
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            1267..1535
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1678
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            1679..1924
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2140
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            2141..2271
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            2272..2328
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            2329..2406
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     exon            2407..3028
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3008..3013
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /note="hexamer: AATAAA"
     polyA_site      3028
                     /gene="Cdh26"
                     /gene_synonym="Gm1010"
                     /note="major polyA site"
ORIGIN      
        1 ctttcctctg gctcagctat aatccccaag gctggatgcc cagccacttt tctgtgtaca
       61 cacataactt cggtgcttag tatccgagcg cccgcttccc tagagccctg tggccacaga
      121 tgaggttata ccttacccat cagcccacct tctctgacaa acgaaagcag ggcagggaac
      181 agagaactca gcaaggtcaa gtgtccaggc tcaggtaccc aagagagtga ttagaagtga
      241 tgtcattggc tggagaggag atgcctggct cctggtgagg ccaccaggca ccaaggactg
      301 ttctgtgccc tccctagcat ggacaccaga ggctgtgcct ggttgctgct gctgctgtca
      361 ttaccgcagg gacagagcca ccagcctcta catcgatcca agagaagatg ggttctcacc
      421 accctggaac tgcaggagga agacccaggg ccctttccta aactggttgg ggagctcttc
      481 aataatatgt caaacaatgt gtcactgata tatttaatca gaggacctgg tgtggacgaa
      541 tttccagaga ttggtttatt ctctatagaa gatcaccaga gtggaaaaat atatgttcac
      601 cgccctgtcg atcgagaagt gacaccgtct tttatggtgc actttgatgc cgtagatcga
      661 tccacaggga aagttgtgga tgaatccctg attttcaaca ttagaatcag agatgtgaat
      721 gaccatgcac cccagtttcc tgagaaggaa tttaacatca gtgtgaaaga gagccaagcc
      781 gcaggtcaac ctatttttca gttgttaacg gtcgatttgg accaagaaaa cactccaaac
      841 tctcaagtcc tttatttcct cgtctctcaa acgccattac tgagggaaag tggctttcgg
      901 attgatctca tcagcgggga agtgcgactc tcgggatgct tacattatga gactgctcct
      961 ctgttcacac tgatcgtcag agcaagtgat tgtggagagc catccctgac atccacggcc
     1021 accattcatg tcagtgtgga agacagcaac aaccacatgc ccacatttat ggaagaccgt
     1081 tatgagattc ggatttctga aggtcaagtc gaacagggtg tgttgtatct ccctgtccaa
     1141 gatggagatt ctccatttac accagcatgg agaacacaat tcaacatatg ggatggcaac
     1201 gaggagggcc attttgatat tgtgactgac cctgagacca accaagggtt gttaagtatt
     1261 atcaagcctt tggattatga atctcaagta gcccatagcc tcgtcgttgt tgtggagaat
     1321 caggagcagc tcttcgtttg tacggagggc cagctgcagc cattgaggaa ggcgatggcc
     1381 agcaccatgg tgagcgtgca ggtgctggac accaatgacc caccagcctt tcaccctcag
     1441 agcttcattg tcagtgagga ggatggagcc tggcccgcca tccagctggg atacttcaat
     1501 gctacagacc cagacagggc tgacagccag ataagataca aactggttca tgatccagaa
     1561 aattgggtga ccgtggatga gaagtcagga gtggtgacca ccaagaagca aatagaccgg
     1621 gagtcccctc atgtgaatga cagtttctat acaatcatcg tccatgcagt tgacaacggc
     1681 cttcccccgc tgactggcac ggggactctg atgcttttcc tatctgatgt caacgacaat
     1741 gctccaaccc tccggcccca ttcccgacac ttggaggtct gtgagtcggc tgggagccag
     1801 cccctgctga tagaagctga ggatgcagat ctggacccct acgctgaccc ctttactttt
     1861 gatttggaca atgctcaggg agacgtggaa gagacttgga tgctgaggac aaagcagggg
     1921 gaaggccact ctgctgaact cacaatgctg agaagcgtcc cgcccgggga ttacttggtg
     1981 ccactcttca tagctgacag acagggcctc gcccagaagc agacagtcca cgtgagaatc
     2041 tgctcctgcc gcagtggctc tgaatgtgag gagccttcgg acacatggct cctgtggtgg
     2101 gccctgtccc cagttggtgc agcacttatg gttctgtcag ctgctctcct ttgcctgctg
     2161 cggtgctcct gcacatttgg acccaagagg ctcagaggct tcatcccaag tgacagtggc
     2221 caccagacac tgattgtgta taacgaggaa agcaaagtcc cttcagccca gggttgtgac
     2281 actttctttg agccaagagg agtgaaaact ttgctgtctt ccaccccggt ctatctggat
     2341 cgtatggtac ccagacagca gcccctgcag ctgctggaag gaagagtggt ggaggcatgg
     2401 agccagaagc tccagagtat tgatgttctg gaaggtgaca ctggctacct gcctcatgtt
     2461 tacagagagg agggcgagtg tgaaggagct gagaccctca gctctctaac cttcttggag
     2521 caggacctct cccccaagtt gctgggctgc tcgggctcaa aatctactcc ctctgaagca
     2581 atgtgtttta catcaagagt tccttcataa aggtgtatga ggggcatgat ttgggaaatt
     2641 gatcactatt catggacctc tccttttgtt ctttattctt agtcacttcc tagtctgcgg
     2701 tggtttgtgt tacagtcact tgggaaacat ctgggagatg tacctctggc atgccagtgg
     2761 gggtttctct tgtttgggtt aaaagagatg ggaagagctg tccactgtgg agggcgacat
     2821 tccctaggct gtgggtgatg ccattccctg gctgggatca tggactgtgt acatggagaa
     2881 agcaagctga gcatcagcgt tcaccactct ctgcttgctg atctcagaag aacatgactg
     2941 gctgctttag actcctgcca cctcgacttc ccgccctgat gaactgtacc cttgaactgt
     3001 gagccagaat aaacccttcc tcctctaa
//
