LOCUS       NM_011800               4021 bp    mRNA    linear   ROD 30-DEC-2022
DEFINITION  Mus musculus cadherin 20 (Cdh20), mRNA.
ACCESSION   NM_011800 XM_984366
VERSION     NM_011800.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4021)
  AUTHORS   Ding Y, Lang D, Yan J, Bu H, Li H, Jiao K, Yang J, Ni H, Morotti S,
            Le T, Clark KJ, Port J, Ekker SC, Cao H, Zhang Y, Wang J, Grandi E,
            Li Z, Shi Y, Li Y, Glukhov AV and Xu X.
  TITLE     A phenotype-based forward genetic screen identifies Dnajb6 as a
            sick sinus syndrome gene
  JOURNAL   Elife 11, e77327 (2022)
   PUBMED   36255053
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4021)
  AUTHORS   Polanco J, Reyes-Vigil F, Weisberg SD, Dhimitruka I and Bruses JL.
  TITLE     Differential Spatiotemporal Expression of Type I and Type II
            Cadherins Associated With the Segmentation of the Central Nervous
            System and Formation of Brain Nuclei in the Developing Mouse
  JOURNAL   Front Mol Neurosci 14, 633719 (2021)
   PUBMED   33833667
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4021)
  AUTHORS   Vagnozzi AN, Garg K, Dewitz C, Moore MT, Cregg JM, Jeannotte L,
            Zampieri N, Landmesser LT and Philippidou P.
  TITLE     Phrenic-specific transcriptional programs shape respiratory motor
            output
  JOURNAL   Elife 9, e52859 (2020)
   PUBMED   31944180
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4021)
  AUTHORS   Hanley O, Zewdu R, Cohen LJ, Jung H, Lacombe J, Philippidou P, Lee
            DH, Selleri L and Dasen JS.
  TITLE     Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of
            Motor Columns
  JOURNAL   Neuron 91 (5), 1005-1020 (2016)
   PUBMED   27568519
REFERENCE   5  (bases 1 to 4021)
  AUTHORS   Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K,
            Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre
            A, Pombero A, Rubenstein JLR, Wakeman WB, Hohmann J, Dee N, Sodt
            AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,
            Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S,
            Wohnoutka P, Hawrylycz MJ, Puelles L and Jones AR.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   6  (bases 1 to 4021)
  AUTHORS   Jung H, Lacombe J, Mazzoni EO, Liem KF Jr, Grinstein J, Mahony S,
            Mukhopadhyay D, Gifford DK, Young RA, Anderson KV, Wichterle H and
            Dasen JS.
  TITLE     Global control of motor neuron topography mediated by the
            repressive actions of a single hox gene
  JOURNAL   Neuron 67 (5), 781-796 (2010)
   PUBMED   20826310
REFERENCE   7  (bases 1 to 4021)
  AUTHORS   Willnow T, Antignac C, Brandli A, Christensen E, Cox R, Davidson D,
            Davies J, Devuyst O, Eichele G, Hastie N, Verroust P, Schedl A and
            Meij I.
  TITLE     The European renal genome project: an integrated approach towards
            understanding the genetics of kidney development and disease
  JOURNAL   Organogenesis 2 (2), 42-47 (2005)
   PUBMED   19521566
REFERENCE   8  (bases 1 to 4021)
  AUTHORS   Moore R, Champeval D, Denat L, Tan SS, Faure F, Julien-Grille S and
            Larue L.
  TITLE     Involvement of cadherins 7 and 20 in mouse embryogenesis and
            melanocyte transformation
  JOURNAL   Oncogene 23 (40), 6726-6735 (2004)
   PUBMED   15273735
  REMARK    GeneRIF: Melanoma cell lines contained transcripts for cadherin-7
            but not for cadherin-20.
REFERENCE   9  (bases 1 to 4021)
  AUTHORS   Haase G, Dessaud E, Garces A, de Bovis B, Birling M, Filippi P,
            Schmalbruch H, Arber S and deLapeyriere O.
  TITLE     GDNF acts through PEA3 to regulate cell body positioning and muscle
            innervation of specific motor neuron pools
  JOURNAL   Neuron 35 (5), 893-905 (2002)
   PUBMED   12372284
REFERENCE   10 (bases 1 to 4021)
  AUTHORS   Faulkner-Jones BE, Godinho LN, Reese BE, Pasquini GF, Ruefli A and
            Tan SS.
  TITLE     Cloning and expression of mouse Cadherin-7, a type-II cadherin
            isolated from the developing eye
  JOURNAL   Mol Cell Neurosci 14 (1), 1-16 (1999)
   PUBMED   10433813
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC101970.11, AK034475.1 and AC158931.4.
            
            [WARNING] On May 3, 2023 this sequence was replaced by NM_011800.6.
            
            On Feb 16, 2018 this sequence version replaced NM_011800.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK034475.1, AF007116.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-299               AC101970.11        96254-96552
            300-514             AK034475.1         2-216
            515-515             AC158931.4         153993-153993
            516-4021            AK034475.1         218-3723
FEATURES             Location/Qualifiers
     source          1..4021
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 49.42 cM"
     gene            1..4021
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /note="cadherin 20"
                     /db_xref="GeneID:23836"
                     /db_xref="MGI:MGI:1346069"
     exon            1..379
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            380..765
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     CDS             520..2925
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /note="cadherin-7"
                     /codon_start=1
                     /product="cadherin-20 precursor"
                     /protein_id="NP_035930.1"
                     /db_xref="CCDS:CCDS15203.1"
                     /db_xref="GeneID:23836"
                     /db_xref="MGI:MGI:1346069"
                     /translation="MWTTGRMSNAKSWLGLGTSLYFWALMDLTATVLSSTPMPEVELE
                     TLFSGRSQSHQRSKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEG
                     AGIVFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDIND
                     NEPKFLDGPYIATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDS
                     KTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQ
                     KHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDINTDQNFQVGI
                     ITVKKPLSFESKKSYTLKVEGSNPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPG
                     FYFVEVPEDVTIGTTIQIISAKDPDVTNNSIRYSIDRGSDPGRFFYVDITTGALMTAR
                     PLDREEFSWHNITVLAMEMNNPSQVGSVAVTIKVLDVNDNAPEFPRFYEAFICENAKA
                     GQLIQTVSAVDQDDPHNGQHFYYSLAPEAANNPNFTVRDNQDNTARILTRRSGFRQQE
                     QSVFYLPILIADSGQPVLSSTGTLTIQVCSCNDDGHVMSCSPEAYLLPVSLSRGALIA
                     ILACIFVLLVLVLLILSMRRHRKQPYIIDDDENIHENIVRYDDEGGGEEDTEAFDIAA
                     MWNPREAQAGAAPKTRQDMLPEIESLSRYVPQTCAVSSTVHSYVLAKLYEADMDLWAP
                     PFDSLQTYMFEGDGSVAGSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASEGPA
                     PLW"
     exon            766..1060
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1180
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1348
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1536
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1790
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..1927
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            1928..2049
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            2050..2167
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2419
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
     exon            2420..4021
                     /gene="Cdh20"
                     /gene_synonym="Cdh7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcgggcta gaaaacgcgc gaaggagggg aagaagcgga ccgcgcgctg gtcttaaagg
       61 acggtgacca gaagaaccag gcagctcttt tcaccctcct ggcagagagc tgagggccgt
      121 gggcatcagc ggatttgctg ctcttgtcat cagctctcca ctgccagaga tcgagcggag
      181 actttggaaa catccgaagg ctgtaaagct gtgacacttt tgacttgggg ggaagggggt
      241 ggggcggggg cacagaggcg agctgaggcg aagggactcg gcaggacacc cgttcgccca
      301 atgaggaagg cagcgatatg agctggacac ccgccactac ggagtctcca cgtctctgga
      361 gagtcgccgg ctgtgccagg acttcagctt gacttgaatg gagatctcct ttgggaagca
      421 atgagtttcc gataatctgt ggtgtggctt gttttatttg gaaaatactc aaccccagtg
      481 cttgccattc tacttgactt ctgaaactcc tgcaagccca tgtggactac gggtagaatg
      541 agcaatgcaa agagttggct tggacttggc acatccttgt acttctgggc gctgatggac
      601 ctcacagcca ctgttctctc cagcactcca atgccagaag ttgaattaga aacactcttc
      661 tctggaaggt cgcagtcaca tcagcgaagc aagaggagct gggtttggaa tcagtttttt
      721 gtcctggaag agtacactgg gactgaccct ttgtatgtcg gcaagcttca ttcagacatg
      781 gacagaggag atggatccat caaatacatc ctttcaggag aaggagcagg catcgtgttt
      841 accattgatg acaccactgg agacatccat gccattcaga ggctcgaccg agaagaaaga
      901 gcccaatata ctctaagggc tcaagcccta gacaggagaa caggccggcc aatggagcca
      961 gaatcagagt tcattatcaa aatccaagat atcaatgaca acgagcccaa gttcctggat
     1021 ggaccttaca tcgccactgt gccagaaatg tcaccagtag gtacatctgt tatccaagtg
     1081 acagccacag atgctgatga cccaacctat ggcaacagtg cccgggtagt gtacagcatt
     1141 ctccagggcc agccatattt ttctgtggac tccaaaacag gtgtaatcag aacagccctt
     1201 atgaacatgg acagagaagc caaggagtac tatgaagtga ttatccaagc caaagatatg
     1261 ggagggcaac ttggaggatt ggctgggacc acaacagtca acatcactct ctcagatgtc
     1321 aatgataacc caccccgatt tccacagaaa cattatcaga tgagtgtgct agaatctgct
     1381 ccaattagct ctactgtggg cagagtgttt gccaaggacc tggatgaagg aatcaatgca
     1441 gagatgaagt ataccattgt ggatggagat ggtgcagatg cttttgatat taatacagac
     1501 caaaacttcc aagttggcat cataactgtg aagaagcccc tgagttttga aagcaagaaa
     1561 agctacaccc tgaaggtgga aggatccaat cctcacctag agatgcgttt tctgaacctt
     1621 ggcccatttc aggacacaac aacagtgcac atcagtgtgg aggatgtgga cgagccccct
     1681 gtgtttgagc ctggctttta ttttgtggag gtgccagagg atgtgacaat tggaacaacc
     1741 atacagatca tttctgctaa ggacccagac gtaaccaaca actcaatcag gtactccatt
     1801 gacagaggca gcgacccggg aagatttttc tatgtggaca ttacaacagg tgctctaatg
     1861 actgcaagac cactagacag agaagagttc tcctggcata atataactgt ccttgctatg
     1921 gaaatgaaca atccctccca agtgggaagt gttgctgtca caatcaaagt cctcgatgtg
     1981 aatgacaacg ctccagagtt tcccagattc tatgaagctt ttatctgtga aaatgccaaa
     2041 gccggacagc tgatccagac agtgagtgct gtggatcaag atgaccctca caatggccaa
     2101 catttctact acagtttggc tcctgaggct gctaacaacc ccaacttcac tgtcagggac
     2161 aaccaagata atactgctcg gattctgacc cggaggtccg gcttccgaca gcaggagcag
     2221 agcgtcttct acctgcccat cctcatcgca gacagcggcc agcccgtcct cagcagcacc
     2281 ggcacgctta ccattcaagt gtgcagctgc aatgacgatg gccacgtcat gtcctgcagc
     2341 ccagaggcct atctgctccc agtcagcttg agtcggggtg ccctcatcgc catcctggcc
     2401 tgcatctttg tcctcttagt gttggtgctg ctcatcctgt ccatgaggcg acatcgcaaa
     2461 caaccctaca tcatcgacga cgatgagaac atccacgaga acattgtgcg ctacgacgac
     2521 gaggggggcg gcgaagagga cacagaggcc ttcgacatcg cagccatgtg gaacccgcgc
     2581 gaggcgcagg caggcgccgc ccccaagacg cgccaggaca tgctccccga gatcgagagc
     2641 ctgtcccgct acgtgcctca gacctgcgcg gtcagcagca cggtccacag ctacgtgctg
     2701 gccaagctct acgaggccga catggacctg tgggccccgc ccttcgactc cctgcagacc
     2761 tacatgtttg aaggggacgg ctctgtggcc ggctcgctca gctccctgca gtcagccacc
     2821 tcggactcag agcagagctt tgatttcctc acggactggg gaccccgctt ccgaaaactg
     2881 gcagaactct acggggcgtc cgaggggccc gcgcccttgt ggtgacagaa gcccggaggc
     2941 aaaggggcac ccaaatccag acgttctcaa aggctgcttc tcatgcccga ggcgcggcca
     3001 ccccaggagc aatattgtgc tggacagtga ggatgggagt gagtggaccc agcagagctc
     3061 tctctggatc agctttactt ggttagacta agctaaataa tcagaaggaa acccaggaga
     3121 agagggcaga atctccaatt accattttaa tttctttttt tgacactgta ttcacaggtt
     3181 tgaattatta aagcttggct ctttttgttt gtttctttat tcctttgttt tttcctattc
     3241 accaaggctt ttgtcacttt accaccaaga aaaggtgcca gtgttaacta cacagatagt
     3301 aggtgagggc gggagtggag gcagggagca agtcctactc tagtttttct gcatcgtcag
     3361 atctgcagaa accaacacac acacacacac acacacacac acacacacac acacacacac
     3421 accactgaaa aattattcct cagtgaaatc atcttacttg ttctaaggtg ggtggtacat
     3481 tatttaactc ttttgagaca aggtttagac tttcccggcc ttgcatgggg aatggttggg
     3541 gagggtggga gaaggaagag acattgacat tgacgtgtgc tctcatgtaa gagctgaaca
     3601 gagagttcgc attgtagctg atccagcatc aacacgttag tgtgcggtgt tctcctgaca
     3661 gctttttatg ccttcgtaaa agccagaagg aaagcagaaa agctgcctcg tgcactgtag
     3721 atgtctcttc tgagtgccaa atgtggagat cagatgcaac aaaagaaagc caaataagaa
     3781 gtatctgata aaagcatggg ttagagggct ttcctaatct gtgtaaagtc aatccaaggg
     3841 atgtttacat actgtagata acctacttga acaaaatcag tattatagag aagaaatgga
     3901 tgtaagagta ttacctgtaa aagttttgta tatttgttaa taattttgtt aataaatatg
     3961 atgtgctaca tctcagtaac ttagcacttc ttttaataaa agctaaatag aaggaaaggt
     4021 g
//
