LOCUS       NM_001412933            2669 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus cell division cycle associated 7 like (Cdca7l),
            transcript variant 1, mRNA.
ACCESSION   NM_001412933 XM_036157374
VERSION     NM_001412933.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2669)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2669)
  AUTHORS   Xiao,M., Wang,J. and Chen,Y.
  TITLE     E2F2 Promotes Wound Healing of Diabetic Foot Ulcer by Regulating
            CDCA7L Transcription
  JOURNAL   Exp Clin Endocrinol Diabetes 131 (3), 162-172 (2023)
   PUBMED   36893788
  REMARK    GeneRIF: E2F2 Promotes Wound Healing of Diabetic Foot Ulcer by
            Regulating CDCA7L Transcription.
REFERENCE   3  (bases 1 to 2669)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2669)
  AUTHORS   Rutledge,E.A., Benazet,J.D. and McMahon,A.P.
  TITLE     Cellular heterogeneity in the ureteric progenitor niche and
            distinct profiles of branching morphogenesis in organ development
  JOURNAL   Development 144 (17), 3177-3188 (2017)
   PUBMED   28705898
REFERENCE   5  (bases 1 to 2669)
  AUTHORS   Amlin-Van Schaick,J.C., Kim,S., DiFabio,C., Lee,M.H., Broman,K.W.
            and Reilly,K.M.
  TITLE     Arlm1 is a male-specific modifier of astrocytoma resistance on
            mouse Chr 12
  JOURNAL   Neuro Oncol 14 (2), 160-174 (2012)
   PUBMED   22234937
REFERENCE   6  (bases 1 to 2669)
  AUTHORS   Machold,R., Klein,C. and Fishell,G.
  TITLE     Genes expressed in Atoh1 neuronal lineages arising from the
            r1/isthmus rhombic lip
  JOURNAL   Gene Expr Patterns 11 (5-6), 349-359 (2011)
   PUBMED   21440680
REFERENCE   7  (bases 1 to 2669)
  AUTHORS   Ou,X.M., Chen,K. and Shih,J.C.
  TITLE     Monoamine oxidase A and repressor R1 are involved in apoptotic
            signaling pathway
  JOURNAL   Proc Natl Acad Sci U S A 103 (29), 10923-10928 (2006)
   PUBMED   16829576
REFERENCE   8  (bases 1 to 2669)
  AUTHORS   Huang,A., Ho,C.S., Ponzielli,R., Barsyte-Lovejoy,D., Bouffet,E.,
            Picard,D., Hawkins,C.E. and Penn,L.Z.
  TITLE     Identification of a novel c-Myc protein interactor, JPO2, with
            transforming activity in medulloblastoma cells
  JOURNAL   Cancer Res 65 (13), 5607-5619 (2005)
   PUBMED   15994933
  REMARK    GeneRIF: Mouse JPO2/RAM2 (Cdca7l) interacts with cMyc.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC139993.16.
            
            On Oct 20, 2022 this sequence version replaced XM_036157374.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422597.405155.1,
                                           SRR13422600.1739224.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164135
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                AC139993.16        47283-47359         c
            78-155              AC139993.16        39226-39303         c
            156-290             AC139993.16        26076-26210         c
            291-422             AC139993.16        21103-21234         c
            423-776             AC139993.16        18803-19156         c
            777-848             AC139993.16        17448-17519         c
            849-1019            AC139993.16        17174-17344         c
            1020-1142           AC139993.16        16434-16556         c
            1143-1292           AC139993.16        15516-15665         c
            1293-1429           AC139993.16        14198-14334         c
            1430-2669           AC139993.16        12534-13773         c
FEATURES             Location/Qualifiers
     source          1..2669
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 63.2 cM"
     gene            1..2669
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /note="cell division cycle associated 7 like"
                     /db_xref="GeneID:217946"
                     /db_xref="MGI:MGI:2384982"
     exon            1..77
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..1448
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /note="isoform 1 is encoded by transcript variant 1; cell
                     division cycle-associated 7-like protein; transcription
                     factor RAM2"
                     /codon_start=1
                     /product="cell division cycle-associated 7-like protein
                     isoform 1"
                     /protein_id="NP_001399862.1"
                     /db_xref="GeneID:217946"
                     /db_xref="MGI:MGI:2384982"
                     /translation="MELATRSQCPLEASHLFCSDASSNLMKSLRAADQIPKEVADIFS
                     APSDDEEFVGFQDDVPMQNLSESCGSLDSRELEKQQNVCFRSKYFTEELRRIFKEDTD
                     SEMEDFEGFTESELNMSSNPELMESELSDSDKAYPVMNDAEEDDEEEAAPRRGRSTRR
                     SSFGLRVAFQFPTKKLARTPDKDSSHLLDSKTDLRRKKSSRQPKGKEDSASDAEDESR
                     AESQENSDALLKRAMNIKENKAMLAQLLAELNSVPDFFPVRTPPSASRRRTPRRAFSE
                     GQITRRMNPTRSARPPEKFALENFTFSATKLTEELYSFRRRKTISGGKCQTYRRHRIS
                     SFRSVKDITEEDLENIAITVRDKVYDKVLGNTCHQCRQKTIDTKTVCRNQSCGGVRGQ
                     FCGPCLRNRYGEDVRTALLDPKWTCPPCRGICNCSYCRRRDGRCATGILIHLAKFYGY
                     DNVKEYLESLQKQL"
     exon            78..155
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            156..290
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            291..422
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            423..776
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            777..848
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            849..1019
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            1020..1142
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1292
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            1293..1429
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..2669
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2651..2656
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /note="hexamer: AATAAA"
     polyA_site      2669
                     /gene="Cdca7l"
                     /gene_synonym="JPO2"
                     /note="major polyA site"
ORIGIN      
        1 gccagcccgg gtggccgcgt gcagggctca gggaagtgag cccagcaggg aagatggagc
       61 tggccacgcg ctcccagtgt cccctagaag caagtcattt gttctgttca gacgccagta
      121 gcaacttaat gaagtcactg agagcagctg accagatccc caaagaagta gctgacatct
      181 tcagtgctcc cagtgacgat gaagagtttg tgggtttcca ggatgatgtt cccatgcaaa
      241 acctgtcaga gagctgtggt agtttggact cacgggagtt ggagaaacag cagaatgtgt
      301 gcttccgttc caaatacttc acagaagaac taagaaggat tttcaaagag gacacggact
      361 cagaaatgga agattttgaa ggatttacag agagcgagct gaacatgagc agtaacccag
      421 agctcatgga gtcggagctg agtgacagtg acaaagcata ccctgtgatg aatgatgcgg
      481 aggaagatga tgaagaggag gctgcaccta gaaggggcag gtccacaaga agaagcagtt
      541 tcggtcttcg ggtagccttt cagttcccca ccaaaaaatt ggcaagaaca ccagataaag
      601 atagctcaca cttgctggac agtaagacgg atcttagaag aaagaagagc tccagacagc
      661 ccaagggaaa ggaggactct gcttctgatg ccgaggatga gtccagagct gagagccaag
      721 agaattcgga tgctctgctg aaaagggcca tgaacatcaa agagaacaag gctatgcttg
      781 ctcagttgtt ggcggaattg aattcggtgc cagatttctt ccctgttcgg acaccacctt
      841 cggcttctag gaggcgaaca ccacgacggg ccttctcaga gggacagatc acacggcgca
      901 tgaacccaac ccggagtgca cgaccccctg aaaagtttgc tctggagaac ttcaccttct
      961 cagccaccaa gcttactgaa gagctttaca gtttcagaag aagaaagaca atcagtgggg
     1021 ggaaatgcca gacgtataga cgtcatcgga tatcttcttt ccgctcagtg aaagacatca
     1081 ctgaggaaga cttggaaaac attgccataa ctgtgcgtga taaagtctat gataaagtgc
     1141 ttggtaacac gtgccatcag tgccggcaga agaccatcga taccaagacg gtctgtcgga
     1201 accagagctg tggtggtgtg cggggacagt tctgtgggcc ctgcctgcgg aatcgctatg
     1261 gggaggatgt gcggacagcg ttgctggatc cgaagtggac atgtcctccc tgccgtggca
     1321 tctgcaattg cagttactgc cggaggcgag atggccgctg tgctactgga attctcattc
     1381 atctggccaa gttctacggt tatgataatg tcaaggagta cctggagagc ttacagaagc
     1441 agctgtagaa gacagtcgag aggagaggga tcgctcgaac ttaaccaggc ggagtcccac
     1501 gagacgagtc tgctctttgt gccagcctta gacgcttgtt ttctagaatt tactggttct
     1561 actgctattg tttcttaaaa gatgtttata tgcttaaaaa ggtttctcag gaaatatagt
     1621 aaagcagaga aatctgtatc catacctgca tagacctgta ttgtgacaag tgtctgctga
     1681 agagttaaaa gcacagtttg agtggggcag agttaatgct caggtaagtt ataaagaaga
     1741 ccttgtctga cagctctcgc ctttgatact cagttccccc acggtcactc ccttcctgca
     1801 gaggctgttg ctttgcctcc tgagtgacca tagctcaaac ctgatagttt atcctgctct
     1861 ggatattaaa ttctgggtca ttaggaattt atattgaaga atgttactct aaactaccaa
     1921 gtgcaattaa ccacacactg tgagtaaggt gtccttttta ttaagagaca atagaaacag
     1981 acactggagg cctcactgtg cttgcctctt ccttcaggac ctgcctggag cctgctgctt
     2041 ctattttttt aaaaaaaaat ttttatagat tatgcttttt atagaacact cactgcattg
     2101 tttccaagtc ttagggatac aagataagcc atggtgtttt gaatgggtgt tgggggaagc
     2161 taaaatcaat aagtattcat cccttatagg tgtgtagtgt ttggtccttg tgtactgtga
     2221 ttactcgccc tcctcaaaga ataattctct aacaaaagaa tgtatacccc tgttactaaa
     2281 acatccttgc tgtgtctggc tgaagctgga gggacgtgag ctgtaaaacc aaggccgttc
     2341 atgcttccag cagtagagcc acacctgcca gtacccactt agctatcctg tctttgctcc
     2401 ttagcctgaa cgtccacacg taggtggggc ctctcgcttt ggttttgtaa acagggcact
     2461 cgtaggcatg cttaatttct tgtctgtcca cgggcacggc tttggcaaag atgacgggca
     2521 tcatggacgt taactcctta aggcgggcat caacaagggc tcctgactgg atgtcccacc
     2581 tggcacctgt ggcagagaca acagttgtgt aactggcatg cgggttctga tgctcttaat
     2641 tgttccatgc aataaatgtt ccactttga
//
