LOCUS       NM_026410               1906 bp    mRNA    linear   ROD 17-JUL-2024
DEFINITION  Mus musculus cell division cycle associated 5 (Cdca5), mRNA.
ACCESSION   NM_026410
VERSION     NM_026410.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1906)
  AUTHORS   Hashimoto,K., Ohira,M., Kodama,A., Kimoto,M., Inoue,M., Tone,S.,
            Usui,Y., Hanashima,A., Goto,T., Ogura,Y., Ujihara,Y. and Mohri,S.
  TITLE     Loss of connectin novex-3 leads to heart dysfunction associated
            with impaired cardiomyocyte proliferation and abnormal nuclear
            mechanics
  JOURNAL   Sci Rep 14 (1), 13727 (2024)
   PUBMED   38877142
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1906)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 1906)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1906)
  AUTHORS   Ulmke,P.A., Sakib,M.S., Ditte,P., Sokpor,G., Kerimoglu,C., Pham,L.,
            Xie,Y., Mao,X., Rosenbusch,J., Teichmann,U., Nguyen,H.P.,
            Fischer,A., Eichele,G., Staiger,J.F. and Tuoc,T.
  TITLE     Molecular Profiling Reveals Involvement of ESCO2 in Intermediate
            Progenitor Cell Maintenance in the Developing Mouse Cortex
  JOURNAL   Stem Cell Reports 16 (4), 968-984 (2021)
   PUBMED   33798452
REFERENCE   5  (bases 1 to 1906)
  AUTHORS   Jordan,P.W., Eyster,C., Chen,J., Pezza,R.J. and Rankin,S.
  TITLE     Sororin is enriched at the central region of synapsed meiotic
            chromosomes
  JOURNAL   Chromosome Res 25 (2), 115-128 (2017)
   PUBMED   28050734
  REMARK    GeneRIF: Results indicate that Sororin regulation during meiosis is
            distinct from its regulation in mitotic cells and may suggest that
            it interacts with a distinctly different partner to ensure proper
            chromosome dynamics in meiosis.
REFERENCE   6  (bases 1 to 1906)
  AUTHORS   Remeseiro,S., Cuadrado,A., Kawauchi,S., Calof,A.L., Lander,A.D. and
            Losada,A.
  TITLE     Reduction of Nipbl impairs cohesin loading locally and affects
            transcription but not cohesion-dependent functions in a mouse model
            of Cornelia de Lange Syndrome
  JOURNAL   Biochim Biophys Acta 1832 (12), 2097-2102 (2013)
   PUBMED   23920377
REFERENCE   7  (bases 1 to 1906)
  AUTHORS   Nishiyama,T., Sykora,M.M., Huis in 't Veld,P.J., Mechtler,K. and
            Peters,J.M.
  TITLE     Aurora B and Cdk1 mediate Wapl activation and release of acetylated
            cohesin from chromosomes by phosphorylating Sororin
  JOURNAL   Proc Natl Acad Sci U S A 110 (33), 13404-13409 (2013)
   PUBMED   23901111
REFERENCE   8  (bases 1 to 1906)
  AUTHORS   Machold,R., Klein,C. and Fishell,G.
  TITLE     Genes expressed in Atoh1 neuronal lineages arising from the
            r1/isthmus rhombic lip
  JOURNAL   Gene Expr Patterns 11 (5-6), 349-359 (2011)
   PUBMED   21440680
REFERENCE   9  (bases 1 to 1906)
  AUTHORS   Nishiyama,T., Ladurner,R., Schmitz,J., Kreidl,E., Schleiffer,A.,
            Bhaskara,V., Bando,M., Shirahige,K., Hyman,A.A., Mechtler,K. and
            Peters,J.M.
  TITLE     Sororin mediates sister chromatid cohesion by antagonizing Wapl
  JOURNAL   Cell 143 (5), 737-749 (2010)
   PUBMED   21111234
REFERENCE   10 (bases 1 to 1906)
  AUTHORS   Rankin,S., Ayad,N.G. and Kirschner,M.W.
  TITLE     Sororin, a substrate of the anaphase-promoting complex, is required
            for sister chromatid cohesion in vertebrates
  JOURNAL   Mol Cell 18 (2), 185-200 (2005)
   PUBMED   15837422
  REMARK    Erratum:[Mol Cell. 2005 May 27;18(5):609]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC131692.5.
            
            On Apr 29, 2007 this sequence version replaced NM_026410.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011701.1, BC052904.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               AC131692.5         68627-68738         c
            113-204             AC131692.5         68346-68437         c
            205-270             AC131692.5         67368-67433         c
            271-306             AC131692.5         67248-67283         c
            307-780             AC131692.5         63311-63784         c
            781-1906            AC131692.5         62062-63187         c
FEATURES             Location/Qualifiers
     source          1..1906
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.34 cM"
     gene            1..1906
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /note="cell division cycle associated 5"
                     /db_xref="GeneID:67849"
                     /db_xref="MGI:MGI:1915099"
     exon            1..112
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..861
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /note="cell division cycle-associated protein 5; sororin
                     p35"
                     /codon_start=1
                     /product="sororin"
                     /protein_id="NP_080686.1"
                     /db_xref="CCDS:CCDS29493.1"
                     /db_xref="GeneID:67849"
                     /db_xref="MGI:MGI:1915099"
                     /translation="MAERRTRSGGAAQRSGPRTSLTKPSKSSKRKSGSDLPNSFSEIW
                     PRTTPAVPVRKAIVLKKIVAHAVEVPDVHTVRRSPRISFILEKENNPPLKVPTKEDLF
                     KTCSVPGTPSSTPVLYTQNVEPDSGEAELDSRDLEMSQKVRRSYSRLQSLGCASTSTP
                     GRRSFFGFEGPDDLPGVSPVVCSKLIETPKVPAKDLVPARTKDLVPDSTKDLVPARTL
                     PGISPPVVKEKRKKKVPEILKSELDKWAVAMNAEFEAAEQFELLIE"
     exon            113..204
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            205..270
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            271..306
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            307..780
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            781..1906
                     /gene="Cdca5"
                     /gene_synonym="2610036L13Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcaaagttcc cggttggcgc gagcctgagt aggcgaccgc ggcggagact gagcccgacc
       61 gtacacatgg cggagcggcg aacacgatca ggaggggctg cccagcggtc tgggcccagg
      121 acttcactta ctaagccttc gaagtcgtcc aagcggaaat ctggctcaga tctcccgaac
      181 tcgttctctg aaatctggcc gaggacaact ccagcggtcc cagtcagaaa ggccatcgtc
      241 ttgaagaaga tcgtagctca tgcagtagag gtcccagatg tccacacggt tcgaagaagt
      301 cctaggatct cttttatttt ggaaaaagag aacaaccctc cgctcaaggt acccacgaaa
      361 gaagacctct tcaagacttg tagtgtccct ggtactccct ccagcacccc cgtgctgtac
      421 actcagaatg ttgagcctga ctctggagaa gcagagctgg acagcagaga cctggaaatg
      481 tctcagaaag tcaggcggtc gtacagtcgg ctacagagcc ttggttgtgc ctcaacctcc
      541 acccctggcc gccgatcctt ctttggcttt gagggacctg acgacttgcc tggagtctca
      601 cctgtcgtgt gttcaaagtt aatcgagacc ccaaaggtac ctgcaaagga cttggttccg
      661 gctagaacga aggacttggt tccagatagt acgaaggact tggttccggc tagaacgctc
      721 cctggaatct ctcccccagt tgtgaaagag aaacgaaaga agaaggttcc tgaaatcctg
      781 aaatcagagc tggataagtg ggctgtggcc atgaatgctg aatttgaagc tgccgagcag
      841 tttgagcttc tgattgaatg agatgaactg ggatgcccgt cattaagtgg ggtgacctgg
      901 ctggctctcc cctcttcctg tacatattgc cttttgagta gagcaggata tgtggggtcc
      961 ctttcactag ccttgttacc cagaaaggta ttgctggcct cttgttatat tgtgtctcct
     1021 tgccctggac tgtctacctc tacagcgttg gggatgagaa tccactgctc tgaaccggaa
     1081 ctgtcagaaa cagggttagc catgggctgt ctctgctgtt gcattcagcc accaaccagc
     1141 agagaggttt tgtgttctgc tttggttctg tagagttgag agatctcaaa gaccagggag
     1201 acagttaaat gcttgaggga ggatttttac attgagtctc tggagtccag gatatgaacg
     1261 ggaggaagca taattggttt ttaacacagt gacttatgta ggaactggtc cgtgtctgtg
     1321 ctctgctgtt gacattggtg aacggggtgc tgctgcttac agcaaagtgg gtacacttga
     1381 tagcgtgggc ctcggatgca ccagtgtaag ctttatagtc tctgctttga cctctttcct
     1441 cgcccacatc tgtttctttg aatacaagct gtgtggcctc agccctagac accatgtcac
     1501 ctcatctctc acctactaga cagcttttgc tgtgagctta aaactattgc tctcatgtga
     1561 gaccaaccat tcctgggggt tgctgggaac aaaagtggat gtatcatggc ttctaaggtt
     1621 ccttcctgcc tgccacctct caatcatggt aaaagctgtg gtttaaaggc cattggcctt
     1681 ccaaccttta cagttcacga gagcagaagc tgtggggaat gagagctcag gtaagctcct
     1741 gctccaccag ggtggcttag tggatcactc ctgcaggctc agtcctcacc cgttcctgaa
     1801 tcatgctgaa ttgctaccat cactgcagac ctacctgcct gtgaggaact agtgtgcagc
     1861 ctaagggcaa ggtggcttga tctcaaataa actgtgtaga agtttc
//
