LOCUS       NM_152810               2994 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus cell division cycle 5-like (Cdc5l), mRNA.
ACCESSION   NM_152810 XM_001002583
VERSION     NM_152810.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2994)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2994)
  AUTHORS   Yao,X., Wang,C., Yu,W., Sun,L., Lv,Z., Xie,X., Tian,S., Yan,L.,
            Li,L. and Liu,J.
  TITLE     BCAS2 regulates oocyte meiotic prophase I by participating in mRNA
            alternative splicing
  JOURNAL   FASEB J 38 (1), e23361 (2024)
   PUBMED   38085152
REFERENCE   3  (bases 1 to 2994)
  AUTHORS   Zhang,J., Liu,W., Li,G., Xu,C., Nie,X., Qin,D., Wang,Q., Lu,X.,
            Liu,J. and Li,L.
  TITLE     BCAS2 is involved in alternative splicing and mouse oocyte
            development
  JOURNAL   FASEB J 36 (2), e22128 (2022)
   PUBMED   34972250
REFERENCE   4  (bases 1 to 2994)
  AUTHORS   Jokoji,G., Maeda,S., Oishi,K., Ijuin,T., Nakajima,M.,
            Tawaratsumida,H., Kawamura,I., Tominaga,H., Taketomi,E., Ikegawa,S.
            and Taniguchi,N.
  TITLE     CDC5L promotes early chondrocyte differentiation and proliferation
            by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1
  JOURNAL   J Biol Chem 297 (2), 100994 (2021)
   PUBMED   34298017
REFERENCE   5  (bases 1 to 2994)
  AUTHORS   Rong,Y., Ji,S.Y., Zhu,Y.Z., Wu,Y.W., Shen,L. and Fan,H.Y.
  TITLE     ZAR1 and ZAR2 are required for oocyte meiotic maturation by
            regulating the maternal transcriptome and mRNA translational
            activation
  JOURNAL   Nucleic Acids Res 47 (21), 11387-11402 (2019)
   PUBMED   31598710
REFERENCE   6  (bases 1 to 2994)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   7  (bases 1 to 2994)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   8  (bases 1 to 2994)
  AUTHORS   Lemon,W.J., Bernert,H., Sun,H., Wang,Y. and You,M.
  TITLE     Identification of candidate lung cancer susceptibility genes in
            mouse using oligonucleotide arrays
  JOURNAL   J Med Genet 39 (9), 644-655 (2002)
   PUBMED   12205107
REFERENCE   9  (bases 1 to 2994)
  AUTHORS   Jiang,C.H., Tsien,J.Z., Schultz,P.G. and Hu,Y.
  TITLE     The effects of aging on gene expression in the hypothalamus and
            cortex of mice
  JOURNAL   Proc Natl Acad Sci U S A 98 (4), 1930-1934 (2001)
   PUBMED   11172053
REFERENCE   10 (bases 1 to 2994)
  AUTHORS   Burns,C.G., Ohi,R., Krainer,A.R. and Gould,K.L.
  TITLE     Evidence that Myb-related CDC5 proteins are required for pre-mRNA
            splicing
  JOURNAL   Proc Natl Acad Sci U S A 96 (24), 13789-13794 (1999)
   PUBMED   10570151
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC163677.2 and
            AC169676.2.
            
            On Mar 21, 2007 this sequence version replaced NM_152810.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC031480.1, AK172950.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-317               AC163677.2         170792-171108
            318-421             AC163677.2         176457-176560
            422-583             AC169676.2         149987-150148       c
            584-711             AC169676.2         149319-149446       c
            712-811             AC169676.2         147968-148067       c
            812-1030            AC169676.2         143068-143286       c
            1031-1175           AC169676.2         140412-140556       c
            1176-1364           AC169676.2         139020-139208       c
            1365-1513           AC169676.2         136589-136737       c
            1514-1676           AC169676.2         135295-135457       c
            1677-1841           AC169676.2         134241-134405       c
            1842-1922           AC169676.2         131803-131883       c
            1923-2165           AC169676.2         131263-131505       c
            2166-2363           AC169676.2         128061-128258       c
            2364-2576           AC169676.2         116460-116672       c
            2577-2994           AC169676.2         115354-115771       c
FEATURES             Location/Qualifiers
     source          1..2994
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 22.36 cM"
     gene            1..2994
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /note="cell division cycle 5-like"
                     /db_xref="GeneID:71702"
                     /db_xref="MGI:MGI:1918952"
     exon            1..317
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     CDS             273..2681
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /note="cell division cycle 5-related protein; cdc5-like
                     protein"
                     /codon_start=1
                     /product="cell division cycle 5-like protein"
                     /protein_id="NP_690023.1"
                     /db_xref="CCDS:CCDS37627.1"
                     /db_xref="GeneID:71702"
                     /db_xref="MGI:MGI:1918952"
                     /translation="MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAK
                     QCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEF
                     LLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLA
                     NTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKKKRGVDYNAEIPFEK
                     KPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKKDKQHLKRKKESDLP
                     SAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSAS
                     STLLSEYNVTNNSIALRTPRTPASQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDF
                     SGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNI
                     NPEDGMADYSDPSYVKQMERESREHLRLGLLGLPAPKNDFEIVLPENAEKELEEREID
                     DTYIEDAADVDARKQAIRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPLNVEPPLT
                     DLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNNSEHITYLEHSPYEKF
                     SKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSRYTRANL
                     ASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWD
                     QIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKELQQRYADLLMEKETL
                     QAKF"
     exon            318..421
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            422..583
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            584..711
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            712..811
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            812..1030
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1175
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1364
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1365..1513
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1676
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1677..1841
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1842..1922
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..2165
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2363
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2364..2576
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
     exon            2577..2994
                     /gene="Cdc5l"
                     /gene_synonym="1200002I02Rik; PCDC5RP"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcgcgcga cacgtcgggc gccttggcac ctgcggtttg attagtctcc atcagtctta
       61 aggttgcagc ctggccgccc gcgtcttttg ccttcggccg ctaagatctc gcgagatttc
      121 ccggggctgc ccacgccgcg cctgcgcaga gctcttcaaa gcagaaggtc gctcttggga
      181 ggaagtggcc ttttgcgtcc cgtgcccgga gcgccgttac tactttctcg aagctctcct
      241 cggctccctt gccgggacac tctgccgcta agatgccccg gattatgatc aaagggggag
      301 tgtggaggaa cacggaggat gaaattctga aagcagcggt aatgaaatat gggaaaaacc
      361 agtggtctag gattgcctca ttgctgcata ggaaatcggc aaagcagtgc aaagccagat
      421 ggtacgaatg gctggatcca agtattaaaa aaactgaatg gtccagagaa gaggaagaaa
      481 aactcttgca cctggccaag ctgatgccaa cgcagtggag gaccattgct ccgatcatag
      541 gaagaacagc agcccagtgc ttggaacact atgagttcct cctggacaaa actgcccaaa
      601 gggacaatga agaagaaaca acagatgacc cccgaaagct taagcctgga gagatagatc
      661 caaacccaga gaccaagcca gcccggcctg acccgataga catggatgag gatgaacttg
      721 agatgctctc cgaggctcga gcccgtctgg ccaatactca aggaaagaag gctaaaagga
      781 aagcaagaga aaagcagttg gaagaagcca ggcgccttgc tgccctccag aaaagacgag
      841 agcttcgagc agctggcata gagattcaga agaaaaggaa aaagaagaga ggcgttgatt
      901 ataatgctga aatcccattt gaaaaaaagc ctgctcttgg tttttatgat acttctgagg
      961 agaattacca ggcccttgat gcagatttca ggaaactgcg gcagcaggat cttgatggag
     1021 agctaagatc tgaaaaagaa ggaagagata ggaaaaaaga caaacagcat ttaaaaagga
     1081 aaaaggagtc tgatttacca tcagctatcc tccaaaccag tggtgtctct gagttcacta
     1141 aaaagagaag caaacttgtg ttgcctgcgc ctcagatttc agatgctgaa ctccaggaag
     1201 ttgtcaaggt aggccaggcc agtgaagtcg cacggcagac ggcggaggag tcaggaataa
     1261 caaactctgc ttctagcact ctcctgtctg agtacaatgt cacaaacaac agcatcgctc
     1321 tgagaacacc acggacacca gcctctcaag acaggattct acaggaagct cagaacctca
     1381 tggccttgac caatgtggac actccattga aaggtgggct taatacccca ctgcatgaga
     1441 gtgacttctc tggtgtgacc ccacagcggc aagttgtgca gactccaaat acagttctgt
     1501 ctaccccttt caggactcct tctaatggag ctgaagggct gactccccga agtggaacaa
     1561 ctcctaaacc agtcactaat gccaccccag gtagaacacc acttagagac aagttaaaca
     1621 ttaatccaga ggatggaatg gcagactaca gtgacccctc ttacgtgaag cagatggaaa
     1681 gagaatctcg tgaacatctc cgtttagggt tgttaggcct ccccgcacct aagaatgatt
     1741 ttgaaattgt tctgcctgaa aatgccgaga aggaactaga agaacgtgaa atagatgata
     1801 cctacattga agatgctgct gatgtggatg ctcgaaagca ggccatccga gatgctgagc
     1861 gtgtaaagga aatgaaacga atgcataaag ctgttcagaa ggatctgccc aggccgtctg
     1921 aagtaaatga aactatttta agacctttaa atgtagaacc acctctaaca gatttacaga
     1981 agagtgaaga actgatcaaa aaagaaatga ttacgatgct tcattatgat cttctacatc
     2041 atccctacga accatctgga aataaaaaag gaaaaaatgt tgggtttgct accaacaatt
     2101 cagagcacat tacctatctt gagcacagcc cttatgagaa gttctccaaa gaagatctga
     2161 aaaaggccca ggatgctctg gtacaagaga tggaagtggt caaacaagga atgagccatg
     2221 gcgaactctc cagtgaagct tacaaccagg tgtgggagga atgctacagt caagtcctct
     2281 atcttcctgc tcagagccgc tacactcgtg ctaatcttgc tagcaaaaag gacagaattg
     2341 aatcacttga aaagagactt gagataaaca ggggtcacat gacaacagaa gccaagagag
     2401 ctgcaaagat ggaaaagaag atgaagattt tgcttggtgg ttaccagtct cgtgctatgg
     2461 ggctcatgaa gcagttgaat gacttatggg accagattga gcaggctcac ttggagctac
     2521 gcacttttga agaactcaag aaacatgaag actctgctat tccccgtagg ctagagtgtc
     2581 taaaagaaga tgtgcagcgg caacaggaac gagagaaaga gcttcagcag agatacgcgg
     2641 atttgctgat ggagaaagag actttacagg caaagttctg aagcacagtg gatgctctgc
     2701 cacaggagat cgagttgctg gtttcctact cagcaaggct gaactgagct tcctcttcat
     2761 tgacaagtta cccagcaccg tggtttctca gttgtttgtt ttgaatgata ctgatctttg
     2821 cgttccgtgt tacagacttg gactccagga taatgagggt ttaaattatc cagatgctca
     2881 ttctttgcca gtgtcatatt tacaaaattt cgtagtttag gcctttaatt taaaaagcct
     2941 gactttaaat actgcctgtg agtaaaccct tgaataaaaa gaacatgtga aaaa
//
