LOCUS       NM_026772               1491 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus CDC42 effector protein 2 (Cdc42ep2), mRNA.
ACCESSION   NM_026772
VERSION     NM_026772.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Trost,M., English,L., Lemieux,S., Courcelles,M., Desjardins,M. and
            Thibault,P.
  TITLE     The phagosomal proteome in interferon-gamma-activated macrophages
  JOURNAL   Immunity 30 (1), 143-154 (2009)
   PUBMED   19144319
REFERENCE   2  (bases 1 to 1491)
  AUTHORS   Schnack,C., Danzer,K.M., Hengerer,B. and Gillardon,F.
  TITLE     Protein array analysis of oligomerization-induced changes in
            alpha-synuclein protein-protein interactions points to an
            interference with Cdc42 effector proteins
  JOURNAL   Neuroscience 154 (4), 1450-1457 (2008)
   PUBMED   18541383
REFERENCE   3  (bases 1 to 1491)
  AUTHORS   Davie,J.K., Cho,J.H., Meadows,E., Flynn,J.M., Knapp,J.R. and
            Klein,W.H.
  TITLE     Target gene selectivity of the myogenic basic helix-loop-helix
            transcription factor myogenin in embryonic muscle
  JOURNAL   Dev Biol 311 (2), 650-664 (2007)
   PUBMED   17904117
REFERENCE   4  (bases 1 to 1491)
  AUTHORS   Joberty,G., Perlungher,R.R. and Macara,I.G.
  TITLE     The Borgs, a new family of Cdc42 and TC10 GTPase-interacting
            proteins
  JOURNAL   Mol Cell Biol 19 (10), 6585-6597 (1999)
   PUBMED   10490598
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB842420.1, AC131692.5 and AC127271.3.
            
            On Mar 4, 2011 this sequence version replaced NM_026772.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK083004.1, SRR3224858.10721.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-98                BB842420.1         2-99
            99-1456             AC131692.5         234889-236246
            1457-1491           AC127271.3         93745-93779
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.34 cM"
     gene            1..1491
                     /gene="Cdc42ep2"
                     /gene_synonym="1110008C05Rik; Borg1; Cep2; D19Bwg1013e"
                     /note="CDC42 effector protein 2"
                     /db_xref="GeneID:104252"
                     /db_xref="MGI:MGI:1929744"
     exon            1..53
                     /gene="Cdc42ep2"
                     /gene_synonym="1110008C05Rik; Borg1; Cep2; D19Bwg1013e"
                     /inference="alignment:Splign:2.1.0"
     exon            54..1491
                     /gene="Cdc42ep2"
                     /gene_synonym="1110008C05Rik; Borg1; Cep2; D19Bwg1013e"
                     /inference="alignment:Splign:2.1.0"
     CDS             372..1016
                     /gene="Cdc42ep2"
                     /gene_synonym="1110008C05Rik; Borg1; Cep2; D19Bwg1013e"
                     /note="binder of Rho GTPases 1; CDC42 effector protein
                     (Rho GTPase binding) 2"
                     /codon_start=1
                     /product="cdc42 effector protein 2"
                     /protein_id="NP_081048.1"
                     /db_xref="CCDS:CCDS29484.1"
                     /db_xref="GeneID:104252"
                     /db_xref="MGI:MGI:1929744"
                     /translation="MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIG
                     SGGGDDMFGDISFLQGKFHLLPGTAVEEAEEDGSFDLPFQFTRTTTVCGRELPDGLSP
                     LLKNAISLPVIGGPQALTLPTAQAPPKPPRLHLESPQPSPQPSPQGAGNVDVWRIPEA
                     GSPHNGMSPEPEAEEPFLSHASSLLSLHVDLGPSILDDVLQIMDHDLGRVQIPT"
     regulatory      1464..1469
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc42ep2"
                     /gene_synonym="1110008C05Rik; Borg1; Cep2; D19Bwg1013e"
                     /note="hexamer: AATAAA"
     polyA_site      1486
                     /gene="Cdc42ep2"
                     /gene_synonym="1110008C05Rik; Borg1; Cep2; D19Bwg1013e"
                     /note="major polyA site"
ORIGIN      
        1 ctggtcctct atcctagccg cacagctctg cagctttgcc cgcgctcctc aagcttctca
       61 actctggact aagaatcttg gaacaagagc aaaccccact gctgttgagg agacctcacc
      121 tttctgcctc cagctctcca aagggacttg catccatcta gaagagagga gggtgtattc
      181 accaccctgt ctttgttggc ctttaatcta actttacctg acaccttggg ccaactttga
      241 tcacatctca ccctctactt ttgttttgtt tttggcaaga gtggacattg gccctctgga
      301 gcctgttttg ggcagagggt gttgagagag tactgaggac tgagcggcca ggactgtgtg
      361 ctgaagtcac catgtccacc aaggtcccca tctatttgaa acgtggcagc cgcaaaggca
      421 agaaagagaa gcttcgggac ctgctgtcct cagacatgat cagcccacca cttggggact
      481 tccgtcacac tattcacatt ggcagcggtg gcggagatga catgtttggg gacatctcct
      541 tcctgcaggg caagttccat ctccttccag gaacagcggt ggaagaggct gaggaggatg
      601 gcagctttga ccttcccttc cagtttactc gcactacaac cgtgtgtggg cgagagctcc
      661 ctgatgggct gtcacctctg ctcaaaaacg ccatctccct ccctgtaatt ggtggccccc
      721 aggccctcac tctgcctaca gcccaggctc cacctaagcc tcctcgcttg caccttgaat
      781 ctccacagcc ttctccacag ccttccccac agggggcagg aaatgtggac gtctggagga
      841 ttccagaggc tggctcgccc cacaatggga tgagccctga gccggaggcc gaggagccct
      901 tcctgtccca tgccagctcc ctgctgtccc tgcatgtgga cctggggcct tcgatcctgg
      961 atgatgtcct ccagattatg gatcacgacc taggccgcgt gcagattcct acataaaacc
     1021 ctcggctggc caggcaggtc gcccaggctg tgctgatgcc tggagacatc tatgggcatt
     1081 ggccctgacc taggagtcag gatcccaggt cacacctatg ggtgctggct agtgactgcc
     1141 attttgagcc tttgttttcc cttctcctaa tggacagagt gtatctttgt tttcatctaa
     1201 caacatccac agaggagcca tgcagaagtt gccttagaga ctcctgaatc tctttggtca
     1261 tttgccctca ctgccaattg ccccctttcc ctcgggtccc tgtggggaag actctgctaa
     1321 aatggagccc ctcctttgtt ggtatcgttg gctatgctcc ccactggtct ttgtgtttgg
     1381 gtctgggagt ccagaaatcg tgacatctcc cgccttgtgt cctgtcccaa cccttcctca
     1441 catgaccagg gaattctggt cgcaataaaa catgttgctg ctggtggctg a
//
