LOCUS       NM_001285988            5690 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus cell division cycle 27 (Cdc27), transcript variant 1,
            mRNA.
ACCESSION   NM_001285988
VERSION     NM_001285988.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5690)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5690)
  AUTHORS   Meziane,H., Birling,M.C., Wendling,O., Leblanc,S., Dubos,A.,
            Selloum,M., Pavlovic,G., Sorg,T., Kalscheuer,V.M., Billuart,P.,
            Laumonnier,F., Chelly,J., van Bokhoven,H. and Herault,Y.
  TITLE     Large-Scale Functional Assessment of Genes Involved in Rare
            Diseases with Intellectual Disabilities Unravels Unique
            Developmental and Behaviour Profiles in Mouse Models
  JOURNAL   Biomedicines 10 (12), 3148 (2022)
   PUBMED   36551904
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5690)
  AUTHORS   Ferguson,C.J., Urso,O., Bodrug,T., Gassaway,B.M., Watson,E.R.,
            Prabu,J.R., Lara-Gonzalez,P., Martinez-Chacin,R.C., Wu,D.Y.,
            Brigatti,K.W., Puffenberger,E.G., Taylor,C.M., Haas-Givler,B.,
            Jinks,R.N., Strauss,K.A., Desai,A., Gabel,H.W., Gygi,S.P.,
            Schulman,B.A., Brown,N.G. and Bonni,A.
  TITLE     APC7 mediates ubiquitin signaling in constitutive heterochromatin
            in the developing mammalian brain
  JOURNAL   Mol Cell 82 (1), 90-105 (2022)
   PUBMED   34942119
REFERENCE   4  (bases 1 to 5690)
  AUTHORS   Huang,J., Ikeuchi,Y., Malumbres,M. and Bonni,A.
  TITLE     A Cdh1-APC/FMRP Ubiquitin Signaling Link Drives mGluR-Dependent
            Synaptic Plasticity in the Mammalian Brain
  JOURNAL   Neuron 86 (3), 726-739 (2015)
   PUBMED   25913861
REFERENCE   5  (bases 1 to 5690)
  AUTHORS   Xie,L., Hoffmann,A.D., Burnicka-Turek,O., Friedland-Little,J.M.,
            Zhang,K. and Moskowitz,I.P.
  TITLE     Tbx5-hedgehog molecular networks are essential in the second heart
            field for atrial septation
  JOURNAL   Dev Cell 23 (2), 280-291 (2012)
   PUBMED   22898775
REFERENCE   6  (bases 1 to 5690)
  AUTHORS   Juriloff,D.M., Harris,M.J. and Dewell,S.L.
  TITLE     A digenic cause of cleft lip in A-strain mice and definition of
            candidate genes for the two loci
  JOURNAL   Birth Defects Res A Clin Mol Teratol 70 (8), 509-518 (2004)
   PUBMED   15329828
REFERENCE   7  (bases 1 to 5690)
  AUTHORS   Listovsky,T., Oren,Y.S., Yudkovsky,Y., Mahbubani,H.M., Weiss,A.M.,
            Lebendiker,M. and Brandeis,M.
  TITLE     Mammalian Cdh1/Fzr mediates its own degradation
  JOURNAL   EMBO J 23 (7), 1619-1626 (2004)
   PUBMED   15029244
REFERENCE   8  (bases 1 to 5690)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 5690)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   10 (bases 1 to 5690)
  AUTHORS   Tugendreich,S., Boguski,M.S., Seldin,M.S. and Hieter,P.
  TITLE     Linking yeast genetics to mammalian genomes: identification and
            mapping of the human homolog of CDC27 via the expressed sequence
            tag (EST) data base
  JOURNAL   Proc Natl Acad Sci U S A 90 (21), 10031-10035 (1993)
   PUBMED   8234252
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603709.14.
            
            On Dec 23, 2022 this sequence version replaced NM_001285988.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC172100.1, SRR9219380.80794.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-150               AL603709.14        96261-96410         c
            151-226             AL603709.14        82493-82568         c
            227-374             AL603709.14        80636-80783         c
            375-500             AL603709.14        77628-77753         c
            501-598             AL603709.14        75239-75336         c
            599-753             AL603709.14        74476-74630         c
            754-965             AL603709.14        74161-74372         c
            966-1080            AL603709.14        72761-72875         c
            1081-1214           AL603709.14        71949-72082         c
            1215-1314           AL603709.14        68621-68720         c
            1315-1522           AL603709.14        67279-67486         c
            1523-1692           AL603709.14        66562-66731         c
            1693-1845           AL603709.14        63274-63426         c
            1846-2054           AL603709.14        61270-61478         c
            2055-2172           AL603709.14        58799-58916         c
            2173-2301           AL603709.14        56069-56197         c
            2302-2376           AL603709.14        54245-54319         c
            2377-2533           AL603709.14        53036-53192         c
            2534-5690           AL603709.14        48422-51578         c
FEATURES             Location/Qualifiers
     source          1..5690
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 67.79 cM"
     gene            1..5690
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="cell division cycle 27"
                     /db_xref="GeneID:217232"
                     /db_xref="MGI:MGI:102685"
     exon            1..150
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..2616
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="isoform 1 is encoded by transcript variant 1; Cell
                     division cycle protein 27 homolog; cell division cycle 27
                     homolog"
                     /codon_start=1
                     /product="cell division cycle protein 27 homolog isoform
                     1"
                     /protein_id="NP_001272917.1"
                     /db_xref="GeneID:217232"
                     /db_xref="MGI:MGI:102685"
                     /translation="MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLL
                     ATCYYRSGKAYKAYRLLKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKS
                     HDDLVTEFGDSACFTLSLLGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGE
                     KPDPDQTFKLTSLQNFSSCLPNTCTTLVSNHSLSHRQPETVLTETPQDTIELNRLNLE
                     SSNSKYSLNTDSSVSYIDSTVISPDNVPLGPGTAILSKQVQNKPKTGRSLLGGPTALS
                     PLTPSFGILPLETPSPGDGSYLQNYTNTPSVIDVAPTGAPTKKTFCVLQSVARMGQTG
                     TKSVFSQSGNSREVTPVLVAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSD
                     SSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGLTQPSINDSLEITKLDSSIISEGKIT
                     TVTPQIQAFNLQKAAAGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYSTGWVL
                     CQIGRAYFELSEYMQAERIFSEVRRIESFRVEGMEIYSTTLWHLQKDVALSVLSKDLT
                     DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD
                     KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG
                     VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP
                     KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPIT
                     QEEQIMGTDESQESSMTDADDTQLHAAESDEF"
     exon            151..226
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            227..374
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            375..500
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            501..598
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            599..753
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            754..965
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1080
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1214
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1314
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1522
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1523..1692
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1693..1845
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..2054
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            2055..2172
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2301
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2376
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            2377..2533
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     exon            2534..5690
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3068..3073
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="hexamer: AATAAA"
     polyA_site      3088
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="major polyA site"
     regulatory      4040..4045
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="hexamer: ATTACA"
     polyA_site      4060
                     /gene="Cdc27"
                     /gene_synonym="APC3"
     regulatory      5427..5432
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="hexamer: ATTAAA"
     regulatory      5449..5454
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="hexamer: AATAAA"
     polyA_site      5450
                     /gene="Cdc27"
                     /gene_synonym="APC3"
     polyA_site      5469
                     /gene="Cdc27"
                     /gene_synonym="APC3"
     regulatory      5669..5674
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc27"
                     /gene_synonym="APC3"
                     /note="hexamer: AATAAA"
     polyA_site      5690
                     /gene="Cdc27"
                     /gene_synonym="APC3"
ORIGIN      
        1 actcggcctc ccccatcccc cggtaacggt cgctggtgag tttaaatgag ccggggctgg
       61 ccgggctgga gccgctacgg ggggggcctg aggcactgca gaaagtgggt ctgagcctca
      121 aggatgacgg tgctgcagga acctgtccag gctgctatat ggcaagcgct aaaccactat
      181 gcttaccgag atgcagtttt cctcgcagaa cgactatatg cagaagtaca ttcagaagaa
      241 gccttgtttt tactggcaac ctgttactac cgctcaggaa aggcttataa agcatataga
      301 ctcttgaaag gacacagttg taccacccca cagtgtaaat acctgcttgc aaaatgttgt
      361 gttgacctca gcaagcttgc agaaggggaa cagatcttat ctggtggagt gtttaataag
      421 cagaaaagcc atgacgacct tgtcactgag tttggagatt cagcttgctt cactctttcc
      481 ttgttgggac atgtgtattg caagacagat cggcttgcca aagggtcaga atgttaccaa
      541 aagagcctta gtttaaatcc tttcctctgg tctccctttg aatcgttatg tgaaataggt
      601 gagaagccag atcctgacca aacatttaaa ttaacatctc tacagaattt tagcagttgt
      661 cttcccaaca cttgtacaac tctagtatct aatcacagtt tatctcacag acagcctgag
      721 acagtcctta cagaaacacc ccaagacaca attgaattaa acagactgaa tttagaatct
      781 tccaattcaa agtactcctt gaatacagat tcctccgtgt cttacattga ttcaactgta
      841 atttcaccag ataacgtccc ccttggacct ggtactgcca tattatctaa acaggttcaa
      901 aataaaccaa aaactggtcg aagtttatta ggaggaccaa ctgctcttag cccattaacc
      961 ccaagttttg ggattttgcc attagaaacc ccaagtcctg gagatggatc ctatttacaa
     1021 aactacacta atacaccttc tgtaattgat gtggcaccca ccggagcacc tacaaaaaag
     1081 actttttgtg ttttacagtc tgttgcaaga atgggccaaa ctggaacaaa gtctgtcttc
     1141 tcacagagtg gaaatagtcg agaggtcaca ccagtacttg ttgcacaaac acaaagttct
     1201 ggcccacaaa caagtacaac acctcaggta ttgagcccca ctatcacatc tcccccaaac
     1261 gcattgcctc ggagaagttc ccgccttttc actagtgaca gttctacaac caaggagaat
     1321 agcaaaaagt taaaaatgaa gtttccacct aaaatcccta acagaaaaac aaaaagtaaa
     1381 actaataaag gaggactaac tcagcccagc ataaacgata gtctggaaat tacaaaactg
     1441 gactcctcta tcatttcaga agggaaaata accacagtca cacctcagat ccaggcattt
     1501 aacctacaaa aggcagcagc aggtttgatg agccttcttc gtgaaatggg aaaaggttat
     1561 ttagctttgt gttcatacaa ctgcaaagaa gctatcaata ttttgagcca tctaccttct
     1621 catcactaca gtactggttg ggtcctatgc cagattggac gggcttattt tgaactttca
     1681 gaatacatgc aggctgaaag aatattctca gaggttagaa ggattgagag tttcagagtt
     1741 gaaggaatgg agatctactc tacaacactc tggcatcttc agaaagacgt tgctctttca
     1801 gttctttcaa aagatttaac agacatggat aagaattcac cagaggcctg gtgtgctgca
     1861 gggaattgtt tcagtctaca acgagagcat gatatagcaa ttaaattctt ccaaagagct
     1921 atccaggtcg atccaaatta cgcttacgcc tatactctat taggacatga gtttgtgtta
     1981 actgaagaac tagataaagc attagcatgt tttcgaaatg ctataagagt aaatcccaga
     2041 cattacaatg catggtatgg tttaggaatg atttattaca agcaagagaa gttcagcctc
     2101 gcagaaatgc atttccagaa agcacttgat atcaaccctc agagttcagt tttactttgc
     2161 cacattggag tagttcagca tgcactaaag aagtctgaga aggctttgga taccctaaac
     2221 aaagccattg ttatcgatcc caagaaccct ctatgcaaat ttcacagagc ctcggtttta
     2281 tttgcaaatg aaaaatacaa gtctgcttta caagaactcg aggaactgaa gcagattgtc
     2341 cccaaagagt ccctcgttta cttcctaata ggaaaggttt acaagaagtt gggtcaaact
     2401 catctcgcct tgatgaattt ctcttgggct atggatttag atcctaaagg agccaataat
     2461 cagattaaag aggcaattga caagcgctac cttccagatg atgaggagcc aataacccag
     2521 gaggaacaga tcatggggac agatgaatcc caggagagca gcatgacaga tgcagatgac
     2581 acacaacttc atgcggcgga aagtgacgaa ttttaacttg tggaagtcag actctgactg
     2641 tgctagtgct gacatgtccc tgtccctcca tacactgagt ctcaactctt gagccgccat
     2701 tgccgtcatt cgtcacctag accatgagtg tgccactttc attggaccct gactgtacac
     2761 agaatggaag gcagtgcgat acttagctgc taacaagact ggctctttta ccagtatgaa
     2821 tgacaatttg ggggaggggt gaggaacttt tcttttttct ttaatctctt cagttggaaa
     2881 tctatcatgg aaggaagagt tatgttttat cttgaaggaa ccattagata cggaaatggt
     2941 gatgaaccag aatttcttgg tcatttttcc aaaattgttt tttatttggt tctattcctg
     3001 ataaacagag taactggcct tcatttctag gtcttcgaga atggtgttag caagtgccag
     3061 atggaacaat aaaagacatt gcctataaca gagtaaagtt cattgccaag gaacatagct
     3121 taccttaagc ttggagtctc tcctataagc aaatgcagtg ggcctgttcg gactcatacg
     3181 gaggagtcaa atatccctcc atacagtgta cacttattct tggcaagaat gctttaatgt
     3241 ctaaccaaga attttaattt attcgtcttg cttcaaagtg ttgatcattg ttgtcttggt
     3301 attgcaaact ttaaaattgg tcttgacgat actggcttta ctccttgagc tctgggatcg
     3361 ccttcaacac tcagagatgg tagcgtggtt ccctgatgaa aagccaagca ggcccttaat
     3421 aaccactgtg tttaccagaa gagtcagtat gagaacacta aagagaaacc ttcgagatca
     3481 tgatagagaa gccttaatac agctggagct gtccctaacc gtgtgtctgc ctctctccca
     3541 ggagtgcaag cacgcatggt gacctctgtt gagtgccgtt ctttcagctc tctacttcgt
     3601 aattgtcagt agtgtgagtc actgcaactt gtcatgggcg taattaattg ggtttaaaat
     3661 actgaacatt tttaacctag gaaaaagttt cttatgaaag agacaaattc tctcctgagt
     3721 tcatcataat atgggtttgt gtgtttgggg actggccaca attttaaaga tctaattatg
     3781 cgtataaaaa tgggaattat tggaatttca caataacaga tttaaacagt cttaaattgt
     3841 gtatctcctt tattgtaatg tattgaaaat tttagagaaa ccttagttaa cattttatta
     3901 agtgccaatg tcagaatata acagattata gtttcttatg ggtgacaggc ctgcagttct
     3961 tattttggaa tgtttgatga aggaaaacct ctcctactgg tcacttgtat atgtaagtca
     4021 agctgtgaaa ataaggtgga ttacagacga tgtggaagaa tgttttagcc tgtagactca
     4081 gtcattttct gtcagttact taaccttctc atccagatgt gaattagaca cagaccatca
     4141 taaagtcaaa gtcttgggtt aggtattagg tgccagggaa acattttaaa ataatttact
     4201 gactaaatct atgtatgtgc cgtttaaaaa aataataatt tatgtgcaaa aggaaaattg
     4261 ggaataaatg accatcataa aaaattccca taggctagca cttcaattct aacagatatt
     4321 ccattttatt attcattagt tgtgtaaagt ttaattttca tttcttttat ttttttaatt
     4381 ggcaaatcgt aagccagcta tatacatata tatattacat tatcagatct agagtttcat
     4441 agcaagcttt accctgagtt ctgttgcaga cctagaaaat gctaagctca gagcataatt
     4501 tactgaagtg taattatctt tttttttttt agtaggagtt tatgtcctgt gccagaggga
     4561 cttctggtgc tgattttaag acaaaggata ggggatggtt gtggcgtggc tggctggaag
     4621 gcactcagac acttggcctg ctttcacagt ttcctcacac ctgcttttaa cagcatttag
     4681 atgcggaagc cttatttcca catagtaact gcttcttggg tctctttctt tttctttgtg
     4741 tctttccttt cctttgcttt ttttttttcc cacagaatag ggatcagata aacaaacaca
     4801 ttttggtaag caagttgttt gtttcaaatt tcagagcttg ctttgaaggg acttaagaat
     4861 cctaagtacc tccttgtctt tgtcacacct acacataagg acacagatac agatacacac
     4921 actcacacac acgtacatta gagcattggg gttttttttt ccttcgtgga aatggttatt
     4981 attactgcac caggatgaat attttttttt tcaagagaac agatggtact caaaataagg
     5041 aaaggtctct taactctttc tgtatttcgt tacttaacaa ttttttattt tacccaagaa
     5101 ctgcaagtaa catttgaacc atgctgctgt tgtaccttaa taactcagtg atcaccagtg
     5161 tttagtccat taaaaacact cttttcgaag aaaacagttt cgaagtctct gattagccag
     5221 agtacactat gggtcttcac tgagaaaaac gaaggcccat tttctttggg aaaacctggg
     5281 aaaatgcaag tgtgggtgtg ccatgtgtgt tctatttgca ttgaaacaat gtacttttgt
     5341 gtcgtctttt ttgcttttcc tgacttattt cagaaattgt atagtctttg gggggaaagt
     5401 cttctctgtt aatatattta cagttcatta aaggatatgg aaaatccaaa taaattactt
     5461 ttgaaagcag tttataatca aggtgttaaa gctatgtaaa agctgtgtca tctgcatttt
     5521 tatactgagc cacagcagca tagtgatgac agatcacatt ttatgttcta caagagccta
     5581 ggacaatgtt tctctaattt ttacttacac tttttaatat ataatatatt aaagttcata
     5641 ccctttttag tattatttgg aatttcaaaa taaatactat gacaaaaaaa
//
