LOCUS       NM_139291               3041 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus cell division cycle 26 (Cdc26), transcript variant 1,
            mRNA.
ACCESSION   NM_139291
VERSION     NM_139291.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3041)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3041)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   3  (bases 1 to 3041)
  AUTHORS   Xie,L., Hoffmann,A.D., Burnicka-Turek,O., Friedland-Little,J.M.,
            Zhang,K. and Moskowitz,I.P.
  TITLE     Tbx5-hedgehog molecular networks are essential in the second heart
            field for atrial septation
  JOURNAL   Dev Cell 23 (2), 280-291 (2012)
   PUBMED   22898775
REFERENCE   4  (bases 1 to 3041)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   5  (bases 1 to 3041)
  AUTHORS   Li,H., Bishop,K.M. and O'Leary,D.D.
  TITLE     Potential target genes of EMX2 include Odz/Ten-M and other gene
            families with implications for cortical patterning
  JOURNAL   Mol Cell Neurosci 33 (2), 136-149 (2006)
   PUBMED   16919471
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732548.9.
            
            On Jan 31, 2019 this sequence version replaced NM_139291.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.329212.1,
                                           SRR7345562.2487040.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-74                AL732548.9         99281-99354         c
            75-171              AL732548.9         95185-95281         c
            172-363             AL732548.9         93453-93644         c
            364-3041            AL732548.9         83073-85750         c
FEATURES             Location/Qualifiers
     source          1..3041
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 33.12 cM"
     gene            1..3041
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /note="cell division cycle 26"
                     /db_xref="GeneID:66440"
                     /db_xref="MGI:MGI:1913690"
     exon            1..74
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            75..171
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            172..363
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             283..540
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /note="CDC26 subunit of anaphase promoting complex; cell
                     division cycle protein 26 homolog"
                     /codon_start=1
                     /product="anaphase-promoting complex subunit CDC26"
                     /protein_id="NP_647452.1"
                     /db_xref="CCDS:CCDS38774.1"
                     /db_xref="GeneID:66440"
                     /db_xref="MGI:MGI:1913690"
                     /translation="MLRRKPTRLELKLDDIEEFESIRKDLEARKKQKEDVEGVGTSDG
                     EGAAGLSSDPKSREQMINDRIGYKPQLKSNNRTSQFGNFEF"
     exon            364..3041
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      780..785
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      802
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /note="major polyA site"
     regulatory      3016..3021
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3041
                     /gene="Cdc26"
                     /gene_synonym="2010012C09Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtagtttggg ctgcgcagca atggagtcat ggtgggagtt gaggttctgg ggaactgcag
       61 aggcctgaaa agagatttcg atagtgactt taatctcagc ataggaagca tctgattaat
      121 gaatgattta cccactgagg acccttagat cctgtggata cctgagaatt gattcatctg
      181 tttgtagctg aggcttggca cctgcagctt ttcctctcct gccatttcac cagcccccag
      241 ctcacgggct ctggctcccc tgaagtcctg ggtgacttca ctatgctgcg acggaaaccg
      301 acccgcttag agctcaagct cgacgacatt gaggagtttg agagcattcg caaggacctg
      361 gaggcccgta agaagcagaa ggaagatgtg gaaggtgtag gaaccagcga tggagaagga
      421 gctgctgggc tcagcagtga ccccaaaagc cgggaacaaa tgattaatga tcgaattggt
      481 tataaacccc aactcaagag caacaaccgc acatctcagt ttggaaactt tgaattttag
      541 agatggattc tcttgtatgc cagacccctg ggacagaata caatgatgac aggagtacca
      601 accagattta gagaattaag tgtgtgcaac caagcagaag gttttctgtc tcctgcaggg
      661 agaggtgact tctgtgtgaa attactgctg tccaaccttt ctgattggct ggaagccaaa
      721 ttctggcttc ttcctggaaa gttggaccgc agaaggctta actgattttt gtttttaaaa
      781 ataaatttat ttttggaaaa aatgtgagac gtccttaaag gtagtagcac tgctaatcgc
      841 cagctctgac aggtaactgc tacaagtgac atcattctcc ttgtctttac aaaaagaccc
      901 caggccccaa acacttgcag ttgatcccct gggctgactt gtttattcac tgtctgctga
      961 ccatccttca agcaacagag atcccagatg agtgtgctca ggctgcaatc cagcacttgg
     1021 gaggctgaag taggaatctc aaagagtcga aggctagtct gggctacaga gcaaaaccct
     1081 gtctcaaaat gtcaaaaaca aacaaacaaa caaacaaact ggagactgga ttcaaatgat
     1141 cagattgtca gaattaaacc cacttccagg aagctttaca ccgggggggg ggggggggga
     1201 agcacaaaca gctgtacagt gagagacatt ctgttcttca cttgggactt cacttgcgca
     1261 gcacccatct gagagctgct ctggatactt tcataccatg ccctattttt accataaaac
     1321 ccagggacag aaccaccagc tgtggaagcc agaacatctg gaatcaagtt tcaaagaaac
     1381 tccttagctg ggatttaccc aggattttgg atagttcaag agtgatgtga atgggaaggt
     1441 agagacagag ggagatgtat agttccctct tctgctccaa gcttttctac aaaaccttta
     1501 ttctagtttt attgatgact tctaagtcct gttatcttcc tgtcttagaa cacaataaaa
     1561 cccccaagac acaggctgta cataagactc tttattattg cagcctgcaa aggccttcca
     1621 gcgggcaaag gaaacaaagg aaaggatctg cctgcctgcc tcagtccttc actgcaactc
     1681 cccagtagga tccccacagt tgtttttgtg cctccctcgt gttttgccct ttgtcctgac
     1741 agctgtcgtg cagagggctg tatgagagtg ctgagtgccg actctcttac ttcctgagag
     1801 ggcacaccat tctgagtttg cagatgcgaa ccagagctca gccacgaagt gggagctgtg
     1861 gagccacctg ctttccaatc ccatgctcct aatggcctca actacattgc tctctaagtg
     1921 gtctcagctg agtctttaag aaagcagtgt gtgggggaga gaaaatttcc tattttcaag
     1981 tttccaagat tttctatgct ttcttttttt ttttttttaa aggtttattt attattatat
     2041 ctaagtacac tgtagctgtc ttcagatgca ccagaagagg gcatcagatc tcattacggg
     2101 tggttttgag ccaccatgtg gttgctggga tttgaactca ggaccttcag aagagcagtc
     2161 ggtgttctta accactgagc cacctctcca gccctatgct ttcttattaa cagaatgaga
     2221 caattattca tcagtagacc aggacttact gcaattgcta atcttttttg ggcataccta
     2281 aattatatgt atcaatgctg tgttccttag gatctgtttg tttcgggact accagcaccc
     2341 aggaggtcac tttattcaga agagtgacct ttcattttcc tgaagccttc aggtgtaata
     2401 taatcagtac acaggaaaaa tgtagtaagg cttgggtgcc tgtcttgtgt gggatgcctt
     2461 atctgtatta ctcttaattt aaataggtgc tagtacttct ttgtgtgtat gcacatgcag
     2521 ggcatgctag ggattggacc tagagcttag aaaggcatac gaggcaagct ctcaaccaac
     2581 tgagctacac ccatagccat ttgtttttgc aacagagtcc ctcgctgtgc agaatcccag
     2641 gcccacctgc aattataccc acctgcagtc ctctctgtct ctatctttat agctggttcc
     2701 gagatccctg ctgctacagg gagagacaga agctgtggag tgtctgtaaa caccacaccc
     2761 aggtgtcagg attatacttc atttcctttg acttacagac caggttgcta gactctagga
     2821 tagtagaggg gctccggtgg gacacatttg ccatctgtat gtacctctcc tccttatttc
     2881 ccctatatcc tgagtggcac attcttttag aattccctcc cttctctctg ccacagaaag
     2941 cagaggtaga cttactggtg ttagggcctg agctctctga gctgctcatg ctgctgtctg
     3001 tgtttttatg gtattaataa acttctggcc caaaaggaaa a
//
