LOCUS       NM_023223               1793 bp    mRNA    linear   ROD 06-DEC-2024
DEFINITION  Mus musculus cell division cycle 20 (Cdc20), mRNA.
ACCESSION   NM_023223
VERSION     NM_023223.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1793)
  AUTHORS   Zhou,B., Feng,C., Sun,S., Chen,X., Zhuansun,D., Wang,D., Yu,X.,
            Meng,X., Xiao,J., Wu,L., Wang,J., Wang,J., Chen,K., Li,Z., You,J.,
            Mao,H., Yang,S., Zhang,J., Jiao,C., Li,Z., Yu,D., Wu,X., Zhu,T.,
            Yang,J., Xiang,L., Liu,J., Chai,T., Shen,J., Mao,C.X., Hu,J.,
            Hao,X., Xiong,B., Zheng,S., Liu,Z. and Feng,J.
  TITLE     Identification of signaling pathways that specify a subset of
            migrating enteric neural crest cells at the wavefront in mouse
            embryos
  JOURNAL   Dev Cell 59 (13), 1689-1706 (2024)
   PUBMED   38636517
REFERENCE   2  (bases 1 to 1793)
  AUTHORS   Kolesova,H., Hrabalova,P., Bohuslavova,R., Abaffy,P.,
            Fabriciova,V., Sedmera,D. and Pavlinkova,G.
  TITLE     Reprogramming of the developing heart by Hif1a-deficient
            sympathetic system and maternal diabetes exposure
  JOURNAL   Front Endocrinol (Lausanne) 15, 1344074 (2024)
   PUBMED   38505753
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1793)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 1793)
  AUTHORS   Iyyappan,R., Aleshkina,D., Ming,H., Dvoran,M., Kakavand,K.,
            Jansova,D., Del Llano,E., Gahurova,L., Bruce,A.W., Masek,T.,
            Pospisek,M., Horvat,F., Kubelka,M., Jiang,Z. and Susor,A.
  TITLE     The translational oscillation in oocyte and early embryo
            development
  JOURNAL   Nucleic Acids Res 51 (22), 12076-12091 (2023)
   PUBMED   37950888
REFERENCE   5  (bases 1 to 1793)
  AUTHORS   Ledvin,L., Gassaway,B.M., Tawil,J., Urso,O., Pizzo,D., Welsh,K.A.,
            Bolhuis,D.L., Fisher,D., Bonni,A., Gygi,S.P., Brown,N.G. and
            Ferguson,C.J.
  TITLE     The anaphase-promoting complex controls a
            ubiquitination-phosphoprotein axis in chromatin during
            neurodevelopment
  JOURNAL   Dev Cell 58 (23), 2666-2683 (2023)
   PUBMED   37875116
REFERENCE   6  (bases 1 to 1793)
  AUTHORS   Asadi,A., Jorgensen,J. and Jacobsson,A.
  TITLE     Elovl1 and p55Cdc genes are localized in a tail-to-tail array and
            are co-expressed in proliferating cells
  JOURNAL   J Biol Chem 277 (21), 18494-18500 (2002)
   PUBMED   11891222
REFERENCE   7  (bases 1 to 1793)
  AUTHORS   Sudakin,V., Chan,G.K. and Yen,T.J.
  TITLE     Checkpoint inhibition of the APC/C in HeLa cells is mediated by a
            complex of BUBR1, BUB3, CDC20, and MAD2
  JOURNAL   J Cell Biol 154 (5), 925-936 (2001)
   PUBMED   11535616
REFERENCE   8  (bases 1 to 1793)
  AUTHORS   Zhang,Y. and Lees,E.
  TITLE     Identification of an overlapping binding domain on Cdc20 for Mad2
            and anaphase-promoting complex: model for spindle checkpoint
            regulation
  JOURNAL   Mol Cell Biol 21 (15), 5190-5199 (2001)
   PUBMED   11438673
REFERENCE   9  (bases 1 to 1793)
  AUTHORS   Yao,J., Liu,Y., Lo,R., Tretjakoff,I., Peterson,A. and Stifani,S.
  TITLE     Disrupted development of the cerebral hemispheres in transgenic
            mice expressing the mammalian Groucho homologue
            transducin-like-enhancer of split 1 in postmitotic neurons
  JOURNAL   Mech Dev 93 (1-2), 105-115 (2000)
   PUBMED   10781944
REFERENCE   10 (bases 1 to 1793)
  AUTHORS   Inbal,N., Listovsky,T. and Brandeis,M.
  TITLE     The mammalian Fizzy and Fizzy-related genes are regulated at the
            transcriptional and post-transcriptional levels
  JOURNAL   FEBS Lett 463 (3), 350-354 (1999)
   PUBMED   10606752
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY736811.1, AK168650.1 and AV499208.1.
            
            On Jan 16, 2008 this sequence version replaced NM_023223.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003215.1, AK160204.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                BY736811.1         8-56
            50-1781             AK168650.1         2-1733
            1782-1793           AV499208.1         242-253
FEATURES             Location/Qualifiers
     source          1..1793
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 54.61 cM"
     gene            1..1793
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /note="cell division cycle 20"
                     /db_xref="GeneID:107995"
                     /db_xref="MGI:MGI:1859866"
     exon            1..403
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..1722
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /note="mmCdc20; cell division cycle 20 homolog"
                     /codon_start=1
                     /product="cell division cycle protein 20 homolog"
                     /protein_id="NP_075712.2"
                     /db_xref="CCDS:CCDS18551.1"
                     /db_xref="GeneID:107995"
                     /db_xref="MGI:MGI:1859866"
                     /translation="MAQFVFESDLHSLLQLDAPIPNAPVARWQRKAKEATGPAPSPMR
                     AANRSHSAGRTPGRTPGKSSSKVQTTPSKPGGDRFIPQRSASQMEVASFLLSKENQPE
                     DRGTPTKKEHQKAWSLNLNGFDVEEAKILRLSGKPQNAPEGYQNRLKVLYSQKATPGS
                     SRKTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQ
                     LLQMEQPGDYISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTSHSARVSSLSW
                     NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVN
                     VWPSGPGESGWAPLQTFTQHQGAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGAC
                     LSAVDVHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTARVLGLT
                     MSPDGATVASAAADETLRLWRCFEMDPALRREREKASVAKSSLIHQGIR"
     exon            404..552
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            553..649
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            650..778
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            779..975
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1070
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1299
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1425
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1543
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1784
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1763..1768
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /note="hexamer: AATAAA"
     polyA_site      1784
                     /gene="Cdc20"
                     /gene_synonym="2310042N09Rik; p55CDC"
                     /note="major polyA site"
ORIGIN      
        1 cgctagcagc ggagagttta agaacaacag tccggcgtgt ccttagcttg tctggaaaag
       61 aacgcgttcg gcaggcgcac tgacgcgctg cgaggagctg ggggtttgtg ttcgggagag
      121 ctgagtacgg agagggaccg ggctgctgcg agctgtggca ggcggagccc aggagcccgg
      181 cgaggatcgc gcttggtcgc ctttcgcccc ggtagcggtg ccatggcgca gttcgtgttc
      241 gagagcgatt tgcactcact gcttcaactg gacgcaccca tccccaatgc cccggttgcg
      301 cgctggcagc gcaaagcaaa ggaagccaca ggcccagccc cctcgcccat gcgggccgcc
      361 aacagatcac acagcgccgg gcggaccccg ggccgaactc ctggcaaatc tagttccaag
      421 gttcagacca cccctagcaa acctggaggt gaccgcttta tcccccaacg cagtgcttct
      481 caaatggagg tggccagctt cctcttaagc aaggaaaacc agccggaaga cagggggacg
      541 cccaccaaaa aggagcatca gaaagcctgg tctctcaacc tgaacggttt tgatgtggag
      601 gaagccaaga tcctcaggct cagcggcaaa cctcagaatg ccccagaagg ctaccagaac
      661 agactgaaag tactgtacag tcagaaagcc acgcctggct ccagcaggaa gacttgcaga
      721 tacatccctt ctctgccaga caggatcctt gatgcccccg aaatccggaa tgactactac
      781 ctgaatcttg tagattggag ctctggaaat gtattggctg tggcactgga caacagtgtg
      841 tacttatgga acgctggttc tggtgacatc ctgcagttgt tgcaaatgga gcagcctgga
      901 gactacatat cctcggtggc ctggatcaag gagggcaact acctagctgt aggcaccagc
      961 aatgctgagg tccagctctg ggatgtgcag cagcagaaac gacttcgaaa catgaccagt
     1021 cactccgctc gagtaagctc cctcagttgg aacagctata tcctatccag tggttcacgg
     1081 tctggccaca tccaccacca tgatgttcgg gtagcagaac accatgtggc cacactgagt
     1141 ggccatagcc aggaagtatg tgggcttcgc tgggccccag atggacgaca tctggcaagt
     1201 ggtggcaatg ataacattgt caacgtgtgg cctagtggtc ctggagaaag tggatgggct
     1261 cccctgcaaa cattcactca acatcaaggc gctgtcaagg ctgtggcatg gtgtccctgg
     1321 cagtccaata tcctggcaac aggaggagga accagtgacc ggcacattcg catttggaac
     1381 gtctgctcag gggcctgtct gagtgctgtg gatgtgcatt cccaggtgtg ctccatcctc
     1441 tggtctcccc actataagga gctgatctca ggtcacggct ttgcccagaa ccagctggtt
     1501 atttggaagt atccaaccat ggccaaggtg gctgagctca aaggacacac agcacgggtc
     1561 ctgggtctta caatgagtcc agatggggcc acagtggcat cagcagcagc tgatgagact
     1621 ctacggttgt ggcgctgctt tgagatggac cctgcccttc ggcgtgagcg ggaaaaagcc
     1681 agtgtagcta aaagtagcct catccaccaa ggcatccgtt gaacaaacgc atttcctttc
     1741 ttgtttttat tttatttttt ctaataaagt tcgtatcttc cttaaaaaaa aaa
//
