LOCUS       NM_027986               2264 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus cytidine and dCMP deaminase domain containing 1
            (Cdadc1), transcript variant 2, mRNA.
ACCESSION   NM_027986 XM_001000245 XM_001000259 XM_001000276 XM_001000293
            XM_001000308 XM_001000321 XM_001000336 XM_001002774 XM_127813
            XM_901847 XM_901853 XM_901857 XM_901866 XM_914101 XM_923072
            XM_923082 XM_923086 XM_923093 XM_923095 XM_985192
VERSION     NM_027986.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2264)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 2264)
  AUTHORS   Liu,Q., Liu,J., Cao,Q., Sha,J., Zhou,Z., Wang,H. and Li,J.
  TITLE     NYD-SP15: a novel gene potentially involved in regulating
            testicular development and spermatogenesis
  JOURNAL   Biochem Genet 44 (7-8), 409-423 (2006)
   PUBMED   16955368
  REMARK    GeneRIF: NYD-SP15 protein plays an important role in testicular
            development and spermatogenesis
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX242881.1, AK032813.1 and CO039661.1.
            
            On Dec 10, 2009 this sequence version replaced NM_027986.2.
            
            Transcript Variant: This variant (2) contains a different 3' coding
            region and UTR, compared to variant 1. The resulting protein
            (isoform 2) has a shorter and distinct C-terminus when it is
            compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.54785.1, AK038926.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                CX242881.1         1-15
            16-1743             AK032813.1         2-1729
            1744-2264           CO039661.1         1-521               c
FEATURES             Location/Qualifiers
     source          1..2264
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 31.48 cM"
     gene            1..2264
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /note="cytidine and dCMP deaminase domain containing 1"
                     /db_xref="GeneID:71891"
                     /db_xref="MGI:MGI:1919141"
     exon            1..205
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     CDS             124..1695
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /EC_number="3.5.4.5"
                     /note="isoform 2 is encoded by transcript variant 2;
                     cytidine and dCMP deaminase domain-containing protein 1;
                     cytidine deaminase"
                     /codon_start=1
                     /product="cytidine and dCMP deaminase domain-containing
                     protein 1 isoform 2"
                     /protein_id="NP_082262.1"
                     /db_xref="CCDS:CCDS36940.1"
                     /db_xref="GeneID:71891"
                     /db_xref="MGI:MGI:1919141"
                     /translation="MKETDQMQSLEGSGAERSVGTQTGSMTGQIPRLSKVNLFTLLSL
                     WMELFPGVEAQGQKSQKTEEESRGPLGDNEELTRVSTEKKQVKKTGLVVVKNMKIIGL
                     HCSSEDLHTGQIALIKHGSRLKNCDLYFSRKPCSACLKMIVNAGVNRISYWPSDPEIS
                     LLTEASSSEDAKLDAKAAERLKSNSRAHVCVLLQPLVCYMVQFVEETSYKCDFIQKTA
                     KALPGADTDFYSECKQERIKEYEMLFLVSNEERHKQILMTIGLESLCEDPYFSNLRQN
                     MKDLILLLATVASSVPNLKHFGFYCSSPEQINEIHNQSLPQEVARHCMVQARLLAYRT
                     EDHKTGVGAVIWAEAKSRSCDGTGAMYFIGCGYNAFPVGSEYADFPHMDDKHKDREIR
                     KFRYIIHAEQNALTFRCQDIKPEERSMIFVTKCPCDECVPLIKGAGIKQIYAGDVDVG
                     KKKADISYMKFGELEGVRKFTWQLNPSEAYSLDPNEPERRENGVLRRRSAKDEQRSSK
                     RPRLETRSAGRATLQ"
     exon            206..303
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            304..378
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            379..556
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            557..1126
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1176
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1346
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1536
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1597
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..2249
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2226..2231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /note="hexamer: AATAAA"
     polyA_site      2249
                     /gene="Cdadc1"
                     /gene_synonym="2310010M10Rik; NYD-SP15"
                     /note="major polyA site"
ORIGIN      
        1 gtcatcttgc tgcgcagaac aagcggttgt tgacaggccg cagaggtggc cgtaggcgag
       61 cttcaaggaa cctatcatgc ctgaccgggc aagctgtcct gggccgaggc ctttgggctg
      121 gggatgaaag aaacggatca gatgcagagt ttggagggtt ccggggccga gaggtcagtc
      181 ggcacgcaga cgggcagcat gacgggtcaa ataccaaggc tttctaaagt gaaccttttc
      241 accctgctca gtctctggat ggagctcttc ccaggagtgg aagcccaagg gcaaaaatct
      301 cagaaaactg aagaggaaag ccgtggtccc ttaggagaca atgaagagtt gaccagagtg
      361 tctactgaaa aaaaacaggt gaagaaaact ggtcttgtgg tggtgaaaaa catgaagatc
      421 attggtcttc actgctccag tgaagactta catactgggc aaattgctct cattaagcat
      481 gggtccaggc tgaaaaactg tgatctttat ttttcaagaa aaccatgttc tgcttgtttg
      541 aaaatgatag tgaatgctgg agttaaccga atttcttact ggccttctga cccagaaata
      601 agtttgctca ctgaagcttc tagttctgaa gatgcaaagc tagatgccaa agccgcagaa
      661 agattgaagt caaacagccg ggcccatgtg tgtgtcttac tccagccgtt ggtgtgttac
      721 atggtgcagt ttgtggagga aacctcttac aaatgtgact ttattcagaa aactgcaaaa
      781 gcgttgccgg gtgctgacac tgatttttat tctgaatgta aacaagaaag aataaaagag
      841 tatgaaatgt tatttttggt ttcaaatgaa gaaaggcata agcagatact gatgactata
      901 ggtctggaga gcctgtgtga agacccctat tttagcaatc taaggcaaaa catgaaagac
      961 ctgattctac ttttggccac agtagcttct agtgtgccca acttgaaaca cttcggattc
     1021 tactgtagca gcccagagca gattaatgaa attcacaatc agagtttgcc acaggaagtt
     1081 gcaaggcatt gcatggtgca ggccaggtta ttggcatatc gaactgagga tcataaaaca
     1141 ggagttggag ctgtcatttg ggcagaagcg aaatctagaa gctgcgatgg gactggagcc
     1201 atgtacttca tagggtgcgg gtacaatgcc tttcccgtgg gctctgagta tgccgacttc
     1261 ccgcacatgg atgacaagca taaggacaga gaaatacgga agttcagata catcatacat
     1321 gcggagcaga acgctttgac atttagatgt caagatataa aaccagaaga acgcagcatg
     1381 atttttgtga caaaatgccc ctgtgatgaa tgtgtgcctt taattaaagg tgcaggcata
     1441 aagcagatct atgctggtga cgtagatgtt ggaaagaaga aagcagacat ctcgtacatg
     1501 aagtttgggg agcttgaggg tgttcgcaaa ttcacatggc agttgaatcc gtctgaagct
     1561 tatagtcttg acccaaatga gcctgaaagg agagaaaacg gtgtattgag gcgcaggtct
     1621 gcaaaggacg aacagcgcag cagcaagagg ccacgtctgg aaacccgctc tgcaggtcgg
     1681 gctacactgc agtaacccac atgctttctt acacgactga gaaactcgta cgaggctgaa
     1741 ctgtaactag ccacagagtg gtgttacctc tgatcttttt atttcagatg tgttgctcag
     1801 catacagtat atgatcttcc aatatactaa atggagtagc aatagtttga gaccagtgta
     1861 agaacagtac ctactggtat ttatccagag gtgatgcagc cagtttgaga agggatcatt
     1921 cacaggaggc gatcttcttt tgatgggtag ttattttgga ttgcaaggat gacaattaat
     1981 aaactgctcc agggaatacg atgacctggc catcttttaa gactccgtgt ataaataacc
     2041 aaaaggctgc attacactca gtccttctac cagccaggac ttgctgaaat agatggactt
     2101 aaaagttgct gtgcccattc tccattttac atgagttgtg taagtggcct gcagatttag
     2161 ttcagtggag tagtgtgtgc aagcatgtgc aaggccctga gttccctcct aagcaccaca
     2221 aaacaaataa aatgttaatt tcacctaaaa aaaaaaaaaa aaaa
//
