LOCUS       NM_007655               1002 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus CD79A antigen (immunoglobulin-associated alpha)
            (Cd79a), mRNA.
ACCESSION   NM_007655 XM_989437
VERSION     NM_007655.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Ogishi,M., Kitaoka,K., Good-Jacobson,K.L., Rinchai,D., Zhang,B.,
            Wang,J., Gies,V., Rao,G., Nguyen,T., Avery,D.T., Khan,T.,
            Smithmyer,M.E., Mackie,J., Yang,R., Arias,A.A., Asano,T.,
            Ponsin,K., Chaldebas,M., Zhang,P., Peel,J.N., Bohlen,J., Levy,R.,
            Pelham,S.J., Lei,W.T., Han,J.E., Fagniez,I., Chrabieh,M., Laine,C.,
            Langlais,D., Gruber,C., Al Ali,F., Rahman,M., Aytekin,C.,
            Benson,B., Dufort,M.J., Domingo-Vila,C., Moriya,K., Shlomchik,M.,
            Uzel,G., Gray,P.E., Suan,D., Preece,K., Chua,I., Okada,S.,
            Chikuma,S., Kiyonari,H., Tree,T.I., Bogunovic,D., Gros,P., Marr,N.,
            Speake,C., Oram,R.A., Beziat,V., Bustamante,J., Abel,L.,
            Boisson,B., Korganow,A.S., Ma,C.S., Johnson,M.B., Chamoto,K.,
            Boisson-Dupuis,S., Honjo,T., Casanova,J.L. and Tangye,S.G.
  TITLE     Impaired development of memory B cells and antibody responses in
            humans and mice deficient in PD-1 signaling
  JOURNAL   Immunity 57 (12), 2790-2807 (2024)
   PUBMED   39603236
REFERENCE   2  (bases 1 to 1002)
  AUTHORS   Priam,P., Krasteva,V., Rousseau,P., Polsinelli,A., Cote,L.,
            Desanlis,I., Farah,A., Lavallee,V.P., Kmita,M. and Lessard,J.A.
  TITLE     Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes
            collaborates with E2a to promote murine lymphoid specification
  JOURNAL   Dev Cell 59 (23), 3124-3140 (2024)
   PUBMED   39232562
REFERENCE   3  (bases 1 to 1002)
  AUTHORS   Wang,Y., Zhang,S., Kang,N., Dong,L., Ni,H., Liu,S., Chong,S.,
            Ji,Z., Wan,Z., Chen,X., Wang,F., Lu,Y., Hou,B., Tong,P., Qi,H.,
            Xu,M.M. and Liu,W.
  TITLE     Progressive polyadenylation and m6A modification of Ighg1 mRNA
            maintain IgG1 antibody homeostasis in antibody-secreting cells
  JOURNAL   Immunity 57 (11), 2547-2564 (2024)
   PUBMED   39476842
REFERENCE   4  (bases 1 to 1002)
  AUTHORS   Mori,S., Kohyama,M., Yasumizu,Y., Tada,A., Tanzawa,K., Shishido,T.,
            Kishida,K., Jin,H., Nishide,M., Kawada,S., Motooka,D., Okuzaki,D.,
            Naito,R., Nakai,W., Kanda,T., Murata,T., Terao,C., Ohmura,K.,
            Arase,N., Kurosaki,T., Fujimoto,M., Suenaga,T., Kumanogoh,A.,
            Sakaguchi,S., Ogawa,Y. and Arase,H.
  TITLE     Neoself-antigens are the primary target for autoreactive T cells in
            human lupus
  JOURNAL   Cell 187 (21), 6071-6087 (2024)
   PUBMED   39276775
REFERENCE   5  (bases 1 to 1002)
  AUTHORS   Tsai,P.J., Chen,M.Y., Hsu,W.C., Lin,S.F., Chan,P.C., Chen,H.H.,
            Kao,C.Y., Lin,W.J., Chuang,T.H., Yu,G.Y. and Su,Y.W.
  TITLE     PTEN acts as a crucial inflammatory checkpoint controlling
            TLR9/IL-6 axis in B cells
  JOURNAL   iScience 27 (7), 110388 (2024)
   PUBMED   39092178
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1002)
  AUTHORS   Clark,M.R., Campbell,K.S., Kazlauskas,A., Johnson,S.A., Hertz,M.,
            Potter,T.A., Pleiman,C. and Cambier,J.C.
  TITLE     The B cell antigen receptor complex: association of Ig-alpha and
            Ig-beta with distinct cytoplasmic effectors
  JOURNAL   Science 258 (5079), 123-126 (1992)
   PUBMED   1439759
REFERENCE   7  (bases 1 to 1002)
  AUTHORS   Matsuuchi,L., Gold,M.R., Travis,A., Grosschedl,R., DeFranco,A.L.
            and Kelly,R.B.
  TITLE     The membrane IgM-associated proteins MB-1 and Ig-beta are
            sufficient to promote surface expression of a partially functional
            B-cell antigen receptor in a nonlymphoid cell line
  JOURNAL   Proc Natl Acad Sci U S A 89 (8), 3404-3408 (1992)
   PUBMED   1373499
REFERENCE   8  (bases 1 to 1002)
  AUTHORS   Flaswinkel,H. and Reth,M.
  TITLE     Molecular cloning of the Ig-alpha subunit of the human B-cell
            antigen receptor complex
  JOURNAL   Immunogenetics 36 (4), 266-269 (1992)
   PUBMED   1639443
REFERENCE   9  (bases 1 to 1002)
  AUTHORS   Travis,A., Hagman,J. and Grosschedl,R.
  TITLE     Heterogeneously initiated transcription from the pre-B- and
            B-cell-specific mb-1 promoter: analysis of the requirement for
            upstream factor-binding sites and initiation site sequences
  JOURNAL   Mol Cell Biol 11 (11), 5756-5766 (1991)
   PUBMED   1922076
REFERENCE   10 (bases 1 to 1002)
  AUTHORS   Campbell,K.S., Hager,E.J., Friedrich,R.J. and Cambier,J.C.
  TITLE     IgM antigen receptor complex contains phosphoprotein products of
            B29 and mb-1 genes
  JOURNAL   Proc Natl Acad Sci U S A 88 (9), 3982-3986 (1991)
   PUBMED   2023945
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB842272.1 and AK143605.1.
            
            On Jun 3, 2018 this sequence version replaced NM_007655.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC027633.1, AK143605.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                BB842272.1         1-14
            15-1002             AK143605.1         2-989
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 13.49 cM"
     gene            1..1002
                     /gene="Cd79a"
                     /gene_synonym="Ig-alpha; Iga; Igalpha; Ly-54; Ly54; mb-1"
                     /note="CD79A antigen (immunoglobulin-associated alpha)"
                     /db_xref="GeneID:12518"
                     /db_xref="MGI:MGI:101774"
     exon            1..92
                     /gene="Cd79a"
                     /gene_synonym="Ig-alpha; Iga; Igalpha; Ly-54; Ly54; mb-1"
                     /inference="alignment:Splign:2.1.0"
     exon            93..386
                     /gene="Cd79a"
                     /gene_synonym="Ig-alpha; Iga; Igalpha; Ly-54; Ly54; mb-1"
                     /inference="alignment:Splign:2.1.0"
     exon            387..505
                     /gene="Cd79a"
                     /gene_synonym="Ig-alpha; Iga; Igalpha; Ly-54; Ly54; mb-1"
                     /inference="alignment:Splign:2.1.0"
     exon            506..574
                     /gene="Cd79a"
                     /gene_synonym="Ig-alpha; Iga; Igalpha; Ly-54; Ly54; mb-1"
                     /inference="alignment:Splign:2.1.0"
     exon            575..1002
                     /gene="Cd79a"
                     /gene_synonym="Ig-alpha; Iga; Igalpha; Ly-54; Ly54; mb-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaactaaccg actcactggg agacgatgcc agggggtcta gaagccctca gagccctgcc
       61 tctcctcctc ttcttgtcat acgcctgttt gggtcccgga tgccaggccc tgcgggtaga
      121 agggggtcca ccatccctga cggtgaactt gggcgaggag gcccgcctca cctgtgaaaa
      181 caatggcagg aaccctaata tcacatggtg gttcagcctt cagtctaaca tcacatggcc
      241 cccagtgcca ctgggtcctg gccagggtac cacaggccag ctgttcttcc ccgaagtaaa
      301 caagaaccac aggggcttgt actggtgcca agtgatagaa aacaacatat taaaacgctc
      361 ctgtggtact tacctccgcg tgcgcaatcc agtccctagg cccttcctgg acatggggga
      421 aggtaccaag aaccgcatca tcacagcaga agggatcatc ttgctgttct gtgcagtggt
      481 gccagggacg ctgctgctat tcaggaaacg gtggcaaaat gagaagtttg gggtggacat
      541 gccagatgac tatgaagatg aaaatctcta tgagggcctg aaccttgatg actgttctat
      601 gtatgaggac atctccaggg gactccaggg cacctaccag gatgtgggca acctccacat
      661 tggagatgcc cagctggaaa agccatgact gacatgtccc acccttccct gcctgccata
      721 tgtctgactc cagcatccct gcctccccac tcttcccctg gagtcccccc ttcccagtgc
      781 ttgctccagc cactcgagtg gcctaccctt gcctccaggc tgccccaccc tattctccca
      841 cctaatcttg tccttcccca agtccagctc cctctctagt gggtaatgag cccttaatcg
      901 ctgcctctag gggagctgat tacagcagcc tcgttagtgt caccccccct cctcccagat
      961 ctgtcatggc cacttaagtg ataataaatc cttcccaaag ca
//
