LOCUS       NM_001159558            3566 bp    mRNA    linear   ROD 02-MAY-2023
DEFINITION  Mus musculus CD36 molecule (Cd36), transcript variant 1, mRNA.
ACCESSION   NM_001159558
VERSION     NM_001159558.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Chen DW, Kang T, Xu XZ, Xia WJ, Ye X, Wu YB, Xu YR, Liu J, Ren H,
            Deng J, Chen YK, Ding HQ, Aslam M, Zelek WM, Morgan BP, Kapur R,
            Santoso S and Fu YS.
  TITLE     Mechanism and intervention of murine transfusion-related acute lung
            injury caused by anti-CD36 antibodies
  JOURNAL   JCI Insight 8 (6), e165142 (2023)
   PUBMED   36809299
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3566)
  AUTHORS   Gauer JS, Duval C, Xu RG, Macrae FL, McPherson HR, Tiede C,
            Tomlinson D, Watson SP and Ariens RAS.
  TITLE     Fibrin-glycoprotein VI interaction increases platelet procoagulant
            activity and impacts clot structure
  JOURNAL   J Thromb Haemost 21 (3), 667-681 (2023)
   PUBMED   36696196
  REMARK    GeneRIF: Fibrin-glycoprotein VI interaction increases platelet
            procoagulant activity and impacts clot structure.
REFERENCE   3  (bases 1 to 3566)
  AUTHORS   Devereux CJ, Bayliss J, Keenan SN, Montgomery MK and Watt MJ.
  TITLE     Investigating dual inhibition of ACC and CD36 for the treatment of
            nonalcoholic fatty liver disease in mice
  JOURNAL   Am J Physiol Endocrinol Metab 324 (2), E187-E198 (2023)
   PUBMED   36629823
  REMARK    GeneRIF: Investigating dual inhibition of ACC and CD36 for the
            treatment of nonalcoholic fatty liver disease in mice.
REFERENCE   4  (bases 1 to 3566)
  AUTHORS   Qu J, Li D, Jin J, Sun N, Wu J, Yang C, Wu L, Zhuang S, Wu H, Chen
            R, Ren Y, Zhong C, Ying L, Zhang Y, Yuan X and Zhang M.
  TITLE     Hypoxia-Inducible Factor 2alpha Attenuates Renal
            Ischemia-Reperfusion Injury by Suppressing CD36-Mediated Lipid
            Accumulation in Dendritic Cells in a Mouse Model
  JOURNAL   J Am Soc Nephrol 34 (1), 73-87 (2023)
   PUBMED   36719147
  REMARK    GeneRIF: Hypoxia-Inducible Factor 2alpha Attenuates Renal
            Ischemia-Reperfusion Injury by Suppressing CD36-Mediated Lipid
            Accumulation in Dendritic Cells in a Mouse Model.
REFERENCE   5  (bases 1 to 3566)
  AUTHORS   Xavier AM, Ludwig RG, Nagai MH, de Almeida TJ, Watanabe HM, Hirata
            MY, Rosenstock TR, Papes F, Malnic B and Glezer I.
  TITLE     CD36 is expressed in a defined subpopulation of neurons in the
            olfactory epithelium
  JOURNAL   Sci Rep 6, 25507 (2016)
   PUBMED   27145700
  REMARK    GeneRIF: Coexpression of the Olfr287 in olfactory sensory neurons
            with CD36 suggests that only a specific set of olfactory receptors
            may be coexpressed with CD36 in these neurons.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3566)
  AUTHORS   Oberland S, Ackels T, Gaab S, Pelz T, Spehr J, Spehr M and Neuhaus
            EM.
  TITLE     CD36 is involved in oleic acid detection by the murine olfactory
            system
  JOURNAL   Front Cell Neurosci 9, 366 (2015)
   PUBMED   26441537
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 3566)
  AUTHORS   Berglund L, Petersen TE and Rasmussen JT.
  TITLE     Structural characterization of bovine CD36 from the milk fat
            globule membrane
  JOURNAL   Biochim Biophys Acta 1309 (1-2), 63-68 (1996)
   PUBMED   8950178
REFERENCE   8  (bases 1 to 3566)
  AUTHORS   Franc NC, Dimarcq JL, Lagueux M, Hoffmann J and Ezekowitz RA.
  TITLE     Croquemort, a novel Drosophila hemocyte/macrophage receptor that
            recognizes apoptotic cells
  JOURNAL   Immunity 4 (5), 431-443 (1996)
   PUBMED   8630729
REFERENCE   9  (bases 1 to 3566)
  AUTHORS   Fernandez-Ruiz E, Armesilla AL, Sanchez-Madrid F and Vega MA.
  TITLE     Gene encoding the collagen type I and thrombospondin receptor CD36
            is located on chromosome 7q11.2
  JOURNAL   Genomics 17 (3), 759-761 (1993)
   PUBMED   7503937
REFERENCE   10 (bases 1 to 3566)
  AUTHORS   Endemann G, Stanton LW, Madden KS, Bryant CM, White RT and Protter
            AA.
  TITLE     CD36 is a receptor for oxidized low density lipoprotein
  JOURNAL   J Biol Chem 268 (16), 11811-11816 (1993)
   PUBMED   7685021
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BQ926044.1, AK128908.1, AK052825.1, BB534670.2 and AW261674.1.
            
            [WARNING] On May 10, 2023 this sequence was replaced by
            NM_001159558.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK128908.1, SRR5189679.134723.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849390 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-429               BQ926044.1         19-447
            430-2784            AK128908.1         207-2561
            2785-3240           AK052825.1         2562-3017
            3241-3432           BB534670.2         330-521
            3433-3538           AW261674.1         1-106               c
            3539-3566           BB534670.2         628-655
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 8.11 cM"
     gene            1..3566
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /note="CD36 molecule"
                     /db_xref="GeneID:12491"
                     /db_xref="MGI:MGI:107899"
     exon            1..249
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            250..303
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            304..397
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            398..607
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     CDS             488..1906
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /note="PAS-4; GPIIIB; PAS IV; glycoprotein IIIb; platelet
                     glycoprotein IV; fatty acid translocase; CD36 antigen"
                     /codon_start=1
                     /product="platelet glycoprotein 4"
                     /protein_id="NP_001153030.1"
                     /db_xref="CCDS:CCDS19100.1"
                     /db_xref="GeneID:12491"
                     /db_xref="MGI:MGI:107899"
                     /translation="MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDMLIEKTIKREVVL
                     EEGTTAFKNWVKTGTTVYRQFWIFDVQNPDDVAKNSSKIKVKQRGPYTYRVRYLAKEN
                     ITQDPEDHTVSFVQPNGAIFEPSLSVGTEDDNFTVLNLAVAAAPHIYQNSFVQVVLNS
                     LIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFYPYNDTVDGVYKVFNGK
                     DNISKVAIIESYKGKRNLSYWPSYCDMINGTDAASFPPFVEKSRTLRFFSSDICRSIY
                     AVFGSEIDLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCK
                     EGKPVYISLPHFLHASPDVSEPIEGLHPNEDEHRTYLDVEPITGFTLQFAKRLQVNIL
                     VKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFKTQVTGKIKLLGMVEMALLG
                     IGVVMFVAFMISYCACKSKNGK"
     exon            608..768
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            769..916
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1096
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1188
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1235
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1305
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1493
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1612
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1613..1686
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1741
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1906
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..3566
                     /gene="Cd36"
                     /gene_synonym="FAT; GPIV; Scarb3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcagagacct atatttatct cctagtaggc gtgggtctga aggactggaa tgctcaggat
       61 gtcaatggct gtcaggcgtc aggataacct agaagataga tgaatggttg agaccccgtg
      121 cctcctccca gaattctcag ctgctccgct gtggaaatgg tgtgtttact ttctgtgtct
      181 ccttcaacag tctccctgaa gccaatctta agatcctgtg actgggcaag caagctgttc
      241 tagaagttgc tgccttctga aatgtgtgga gcaactggtg gatggtttcc tagcctttca
      301 aaggtagttt acaaatgatt tgaagtgctg atcctttcag agtctcaaca gattatttct
      361 taaacagctc atacattgct gtttatgcat gaattagtag aaccgggcca cgtagaaaac
      421 actgtgattg tacctgggag ttggcgagaa aaccagtgct ctcccttgat tctgctgcac
      481 gaggagaatg ggctgtgatc ggaactgtgg gctcattgct ggagctgtta ttggtgcagt
      541 cctggctgtg tttggaggca ttctcatgcc agtcggagac atgcttattg agaagacaat
      601 caaaagggaa gttgtccttg aagaaggaac cactgctttc aaaaactggg ttaaaacagg
      661 caccactgtg tacagacagt tttggatctt tgatgtgcaa aacccagatg acgtggcaaa
      721 gaacagcagc aaaatcaagg ttaaacaaag aggtccttac acatacagag ttcgttatct
      781 agccaaggaa aatataactc aggaccccga ggaccacact gtgtcttttg tacagcccaa
      841 tggagccatc tttgagcctt cactgtctgt tggaacagag gatgacaact tcacagttct
      901 gaatctggct gtagcagctg caccacatat ctaccaaaat tcatttgttc aagttgtgct
      961 caactctctt ataaaaaagt ccaagtcttc tatgttccaa acaagatctt tgaaagaact
     1021 cttgtggggt tacaaagatc cattcctcag tttggttcca tatcctataa gtaccacagt
     1081 tggtgtgttt tatccttaca atgacactgt agatggagtt tataaagttt tcaatggaaa
     1141 ggataacata agcaaagttg ccataattga gtcctataaa gggaaaagga atttgtccta
     1201 ttggccaagc tattgcgaca tgattaatgg cacagacgca gcctcctttc caccttttgt
     1261 tgaaaagtct cggacattga gattcttttc ctctgacatt tgcaggtcta tctacgctgt
     1321 gttcggatct gaaatcgacc ttaaaggaat ccccgtgtac agatttgttc ttccagccaa
     1381 tgcctttgca tcacccctcc agaatccaga caaccattgt ttctgcactg aaaaagtaat
     1441 ctccaataac tgtacatctt atggtgtgct agacattggc aaatgcaaag aaggaaagcc
     1501 tgtgtatatt tcgcttccac atttcctaca tgcaagtcca gatgtttcag aacctattga
     1561 aggcttacat ccaaatgaag atgagcatag gacatactta gatgtggaac ccataactgg
     1621 attcactcta caatttgcaa aacgactgca ggtcaacata ttggtcaagc cagctagaaa
     1681 aatagaagca ttaaagaatc tgaagagacc ttacattgta cctatactgt ggctaaatga
     1741 gactgggacc attggtgatg aaaaagcaga aatgttcaaa acacaagtga ctgggaaaat
     1801 caagctcctt ggcatggtag agatggcctt acttgggatt ggagtggtga tgtttgttgc
     1861 ttttatgatt tcatattgtg cttgcaaatc caagaatgga aaataagtag tggatgagcc
     1921 tacatataca ctggctacat ctttggtaaa gccgatctac aaaatgaaaa cttaatatat
     1981 gcttcgtttt tacaaaacac acctatcttt aggagaagaa atggtggtgt gtgctctctc
     2041 tctctttctc tttctctctt attgcagata tatatttatt tgtaaatata tatatatgca
     2101 ataagtcaca gcatatttca aaagattaat atgtcactat aggcaatatt ttttaataaa
     2161 atcttgcact tttattaaaa gtccatcatt tgcaactgag tggacttcaa tttctgtaga
     2221 cccaattatc ctgtttggtt ctgatttact gatttgttcc atgttggcaa atttcaagaa
     2281 tgtacattct gagaaatttt tgttttccct cactggagga aactgctatc atgactgggg
     2341 tggccccttt gtttatagca aatttggctt gcaactgtca gcacatggca taagtataac
     2401 atcttgaaag acttaagaat gaaaaatgaa caattcacat gtgagccact gcttatatat
     2461 taagtctctc cctctctgga gttcttggct acagcaaggc cagatatcac attggttttg
     2521 gttttgttgt ttttgttttg tttttgtttt ttactctctg acacagagct tatgaaatgg
     2581 actttttttt ttttttttag cataccttag ctctttgtat tttaagtatg tcgtcatgtt
     2641 ccatgctgca tagctcttta aaaaacctga gtaggttttt ctctttctgc tcagctgcaa
     2701 ctaataacaa ccttggagag ctgttatagt gttaaaagat gtaaatgata ataaaagaat
     2761 tattaaatgg aatcctacaa aagcaacaat gggctttaat atatatttgt ggtaatatct
     2821 cctgctttca taatcaccca aaaaaaggac tggtttctaa cattaaaaga agtcgttcct
     2881 taaattcaac ctttttgtct agttactatt gaatcacagt atgttattta ttgtatttta
     2941 ttttgttttt tgtagaagtg ttctatctga gattctgtgt ccttctgaat catttaacct
     3001 ttctgctatg tcttaatgca attgaacaca gatattttgt tataatttta tagcagcagt
     3061 gtgagactga aggcaaatat tttccagggt aagacacagt gataggttgt tctacttcct
     3121 ttagcagcat aatcaatttc acttagtatt agtcccaata aattctggta taagacacaa
     3181 aataaaaaca aacattttct gttctatacg tagaaaaata aaaggaaagg tgagacaact
     3241 aactctcttg tctagatata aaaataatca aaactgcatg gcagctttgg gcaggagtgc
     3301 tggattagtg gttaggagtc atcaatgttc ctacagaaga cctgggcttg gtacccagct
     3361 tctatacgtc tgctcacagc ctcatatgat tcctgtcagt tgatactatg cccgcctctc
     3421 ctgtgcaccc ttctgcactg catgtggtga tcatttatac actcaggtat gcatgcacac
     3481 atggaattta aagaggctgg aagagtgtat gagaaggttg tagaggagaa aggagtgtgg
     3541 gaaacgatgt cattaaaatc agattt
//
