LOCUS       NM_001290660            1363 bp    mRNA    linear   ROD 08-JUN-2024
DEFINITION  Mus musculus CD302 antigen (Cd302), transcript variant 1, mRNA.
ACCESSION   NM_001290660 XM_006499999
VERSION     NM_001290660.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Lo,T.H., Silveira,P.A., Fromm,P.D., Verma,N.D., Vu,P.A.,
            Kupresanin,F., Adam,R., Kato,M., Cogger,V.C., Clark,G.J. and
            Hart,D.N.
  TITLE     Characterization of the Expression and Function of the C-Type
            Lectin Receptor CD302 in Mice and Humans Reveals a Role in
            Dendritic Cell Migration
  JOURNAL   J Immunol 197 (3), 885-898 (2016)
   PUBMED   27316686
  REMARK    GeneRIF: These studies confirm a functional role for CD302 in
            myeloid dendritic cells migration.
REFERENCE   2  (bases 1 to 1363)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   3  (bases 1 to 1363)
  AUTHORS   Yasuda,S., Hasegawa,T., Hosono,T., Satoh,M., Watanabe,K., Ono,K.,
            Shimizu,S., Hayakawa,T., Yamaguchi,T., Suzuki,K. and Sato,Y.
  TITLE     AW551984: a novel regulator of cardiomyogenesis in pluripotent
            embryonic cells
  JOURNAL   Biochem J 437 (2), 345-355 (2011)
   PUBMED   21554246
REFERENCE   4  (bases 1 to 1363)
  AUTHORS   Kato,M., Khan,S., d'Aniello,E., McDonald,K.J. and Hart,D.N.
  TITLE     The novel endocytic and phagocytic C-Type lectin receptor
            DCL-1/CD302 on macrophages is colocalized with F-actin, suggesting
            a role in cell adhesion and migration
  JOURNAL   J Immunol 179 (9), 6052-6063 (2007)
   PUBMED   17947679
  REMARK    GeneRIF: hDCL-1 is an unconventional lectin receptor that plays
            roles not only in endocytosis/phagocytosis but also in cell
            adhesion and migration
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AI116405.1, AK002812.1 and AA222439.1.
            
            On Mar 15, 2014 this sequence version replaced XM_006499999.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY703317.1, DV046556.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-360               AI116405.1         1-360
            361-1007            AK002812.1         2-648
            1008-1363           AA222439.1         119-474
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 34.5 cM"
     gene            1..1363
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /note="CD302 antigen"
                     /db_xref="GeneID:66205"
                     /db_xref="MGI:MGI:1913455"
     exon            1..425
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             365..1051
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; C-type lectin domain family 13 member A; type I
                     transmembrane C-type lectin receptor DCL-1"
                     /codon_start=1
                     /product="CD302 antigen isoform a precursor"
                     /protein_id="NP_001277589.1"
                     /db_xref="CCDS:CCDS71058.1"
                     /db_xref="GeneID:66205"
                     /db_xref="MGI:MGI:1913455"
                     /translation="MPHAALSSLVLLSLATAIVADCPSSTWVQFQGSCYAFLQVTINV
                     ENIEDVRKQCTDHGADMVSIHNEEENAFILDTLQKRWKGPDDLLLGMFYDTDDATFKW
                     YDHSNMTFDKWADQDGEDLVDTCGFLYTKTGEWRKGDCEISSVEGTLCKAAIPYDKKY
                     LSDNHILISTLVIASTVTLAVLGAIIWFLYRRNARSGFTSFSPAPLSPYSDGCALVVA
                     EEDEYAVQLD"
     exon            426..536
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            537..653
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            654..824
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            825..851
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            852..1350
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1331..1336
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1350
                     /gene="Cd302"
                     /gene_synonym="1110055L24Rik"
                     /note="major polyA site"
ORIGIN      
        1 aatgccacaa gtgctatgga ttagtcaaca gtgctccacc aatgctctgt cctggttcct
       61 atccttgcac tgatgttatg taagatgcta acatttggag aagctgccgc aaggattacg
      121 ggaagttcta tttatttttg caacatttta gaaagtctga gattacttca gttcaaatga
      181 gaagtttatc tttaacgaag agaagttgga gtctgcggtg tgtccgccgc ttggggatct
      241 gagcgtccca gcagtgcgac cctgggctcc actcccccgc ctcgagtggg aggcgtcgca
      301 actgagctgg gagctgcgca cccgacaagc accgcccccg gcccgctctc ggcgccgcgc
      361 agtcatgccc cacgcagcgc tgtcctcgct cgtgctgctg agcctcgcca ctgccatcgt
      421 cgccgactgt ccttcatcta cctgggtcca gttccaaggc agctgttatg cttttcttca
      481 agtaaccatc aatgtggaaa acatagagga tgtcagaaaa cagtgcactg accacggggc
      541 agacatggta agcatacaca atgaagagga aaacgcgttt atactggaca ctttgcaaaa
      601 gcgatggaag ggtccagatg atctcctgct aggcatgttc tatgacactg atgatgcaac
      661 tttcaagtgg tatgatcatt caaatatgac attcgacaag tgggcagatc aagatggtga
      721 ggacctagtt gatacctgtg gttttctgta caccaagaca ggtgaatgga gaaaagggga
      781 ttgtgaaatc tcttctgtgg agggaacact ttgcaaagca gcaatcccat atgacaagaa
      841 gtatttatca gataaccaca ttttaatatc gactctggtg atcgctagca cagtaactct
      901 ggcagttttg ggagcgatca tttggttcct ctatagaaga aacgcgcgct ctggcttcac
      961 ctctttttca cctgcaccac tgtcacctta cagtgatggc tgtgccctgg tagttgcaga
     1021 agaagatgaa tatgctgttc agctggacta agagtttggt aatatcaggc cagcatattg
     1081 aatccattga caataatttc ctgtgcaagg ttttcatata aaaacttgcc acaaaaactg
     1141 agccttttat ggttattctt atatcagtat tttcatgtat taaatgtgac aaaacattaa
     1201 ccttctaaga aaaaatatat ataaaataaa aaatataaaa atattaagtt tcagaacagg
     1261 aaccatcctg gatctaactt acacgttttc ttgtgtagtt ttcatttgag tacatgaaag
     1321 ctgcaagtac aataaagctg gtaaaacgcc aaaaaaaaaa aaa
//
