LOCUS       NM_145437               2440 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus CD300 molecule like family member d (Cd300ld), mRNA.
ACCESSION   NM_145437 XM_909923
VERSION     NM_145437.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2440)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2440)
  AUTHORS   Wang,C., Zheng,X., Zhang,J., Jiang,X., Wang,J., Li,Y., Li,X.,
            Shen,G., Peng,J., Zheng,P., Gu,Y., Chen,J., Lin,M., Deng,C.,
            Gao,H., Lu,Z., Zhao,Y. and Luo,M.
  TITLE     CD300ld on neutrophils is required for tumour-driven immune
            suppression
  JOURNAL   Nature 621 (7980), 830-839 (2023)
   PUBMED   37674079
  REMARK    GeneRIF: CD300ld on neutrophils is required for tumour-driven
            immune suppression.
REFERENCE   3  (bases 1 to 2440)
  AUTHORS   Haga,K., Fujimoto,A., Takai-Todaka,R., Miki,M., Doan,Y.H.,
            Murakami,K., Yokoyama,M., Murata,K., Nakanishi,A. and Katayama,K.
  TITLE     Functional receptor molecules CD300lf and CD300ld within the CD300
            family enable murine noroviruses to infect cells
  JOURNAL   Proc Natl Acad Sci U S A 113 (41), E6248-E6255 (2016)
   PUBMED   27681626
  REMARK    GeneRIF: Our results indicate that direct interaction of MNV with
            two cell-surface molecules, CD300lf and CD300ld, dictates
            permissive noroviral infection.
REFERENCE   4  (bases 1 to 2440)
  AUTHORS   Orchard,R.C., Wilen,C.B., Doench,J.G., Baldridge,M.T., McCune,B.T.,
            Lee,Y.C., Lee,S., Pruett-Miller,S.M., Nelson,C.A., Fremont,D.H. and
            Virgin,H.W.
  TITLE     Discovery of a proteinaceous cellular receptor for a norovirus
  JOURNAL   Science 353 (6302), 933-936 (2016)
   PUBMED   27540007
REFERENCE   5  (bases 1 to 2440)
  AUTHORS   Enomoto,Y., Yamanishi,Y., Izawa,K., Kaitani,A., Takahashi,M.,
            Maehara,A., Oki,T., Takamatsu,R., Kajikawa,M., Takai,T.,
            Kitamura,T. and Kitaura,J.
  TITLE     Characterization of leukocyte mono-immunoglobulin-like receptor 7
            (LMIR7)/CLM-3 as an activating receptor: its similarities to and
            differences from LMIR4/CLM-5
  JOURNAL   J Biol Chem 285 (46), 35274-35283 (2010)
   PUBMED   20817736
  REMARK    GeneRIF: Data show that LMIR7/CLM-3 shares similarities with
            LMIR4/CLM-5, although they are differentially regulated in their
            distribution, expression, and function.
REFERENCE   6  (bases 1 to 2440)
  AUTHORS   Nakano,T., Tahara-Hanaoka,S., Nakahashi,C., Can,I., Totsuka,N.,
            Honda,S., Shibuya,K. and Shibuya,A.
  TITLE     Activation of neutrophils by a novel triggering immunoglobulin-like
            receptor MAIR-IV
  JOURNAL   Mol Immunol 45 (1), 289-294 (2008)
   PUBMED   17543387
  REMARK    GeneRIF: MAIR-IV may regulate activation of neutrophils and play an
            important role for innate immunity.
REFERENCE   7  (bases 1 to 2440)
  AUTHORS   Izawa,K., Kitaura,J., Yamanishi,Y., Matsuoka,T., Oki,T.,
            Shibata,F., Kumagai,H., Nakajima,H., Maeda-Yamamoto,M.,
            Hauchins,J.P., Tybulewicz,V.L.J., Takai,T. and Kitamura,T.
  TITLE     Functional analysis of activating receptor LMIR4 as a counterpart
            of inhibitory receptor LMIR3
  JOURNAL   J Biol Chem 282 (25), 17997-18008 (2007)
   PUBMED   17438331
  REMARK    GeneRIF: the innate immune system is at least in part regulated by
            the qualitative and quantitative balance of the paired receptors
            LMIR3 and LMIR4
REFERENCE   8  (bases 1 to 2440)
  AUTHORS   Chung,D.H., Humphrey,M.B., Nakamura,M.C., Ginzinger,D.G.,
            Seaman,W.E. and Daws,M.R.
  TITLE     CMRF-35-like molecule-1, a novel mouse myeloid receptor, can
            inhibit osteoclast formation
  JOURNAL   J Immunol 171 (12), 6541-6548 (2003)
   PUBMED   14662855
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL607025.21.
            
            On Nov 17, 2006 this sequence version replaced NM_145437.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC019814.1, AK028662.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               AL607025.21        66097-66212         c
            117-458             AL607025.21        63629-63970         c
            459-585             AL607025.21        62421-62547         c
            586-2440            AL607025.21        58769-60623         c
FEATURES             Location/Qualifiers
     source          1..2440
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 80.56 cM"
     gene            1..2440
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /note="CD300 molecule like family member d"
                     /db_xref="GeneID:217305"
                     /db_xref="MGI:MGI:2442358"
     exon            1..116
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..742
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /note="CMRF35-like molecule 5; leukocyte mono-Ig-like
                     receptor 4; myeloid-associated immunoglobulin (Ig)-like
                     receptor IV; novel immunoglobulin V-set protein (Clm5);
                     MAIR-4; myeloid-associated immunoglobulin-like receptor 4;
                     CD300 antigen like family member D"
                     /codon_start=1
                     /product="CMRF35-like molecule 5 precursor"
                     /protein_id="NP_663412.1"
                     /db_xref="CCDS:CCDS25615.1"
                     /db_xref="GeneID:217305"
                     /db_xref="MGI:MGI:2442358"
                     /translation="MWQFSALLLFFLPGCCTAQDSVTGPEEVSGQEQGSLTVQCRYSS
                     YWKGYKKYWCRGVPQRSCDILVETDKSEQLVKKNRVSIRDNQRDFIFTVTMEDLRMSD
                     AGIYWCGITKGGPDPMFKVNVNIDQAPKSSMMTTTATVLKSIQPSAENTGKEQVTQSK
                     EVTQSRPHTRSLLSSIYFLLMVFVELPLLLSMLSAVLWVTRPQRCFGRGENDLVKTHS
                     PVA"
     exon            117..458
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /inference="alignment:Splign:2.1.0"
     exon            459..585
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /inference="alignment:Splign:2.1.0"
     exon            586..2440
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /inference="alignment:Splign:2.1.0"
     regulatory      763..768
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /note="hexamer: AAGAAA"
     polyA_site      786
                     /gene="Cd300ld"
                     /gene_synonym="4732429D16Rik; Cd300ld1; clm-5; CLM5;
                     LMIR4; MAIR-IV"
                     /note="major polyA site"
ORIGIN      
        1 ggcaactcaa gctgagctgc gagtcctcac agggtcctga catctgtcgt caacaaggac
       61 atgagaggag acgaccatgt ggcagttctc tgctctactc ctattcttcc tcccaggctg
      121 ctgcacggct caggattcag tcacaggtcc agaggaggtg agcggtcagg agcagggctc
      181 cttgacagtg cagtgcagat attcctcata ctggaagggt tacaagaagt actggtgccg
      241 aggagttcct cagagatcat gtgatattct tgttgaaacc gataaatcag agcagctggt
      301 gaagaagaac cgtgtgtcca tcagggacaa ccagagagac ttcatcttca cagtgaccat
      361 ggaggatctg aggatgagcg atgctggcat ttactggtgt ggaattacga aaggtggacc
      421 tgatcccatg tttaaagtta atgtgaacat tgaccaagcc ccaaaaagtt caatgatgac
      481 caccacagcc acagttctga aatccataca accaagcgct gagaacactg gcaaggaaca
      541 agtgactcag agcaaagaag tgactcagag caggccccac accaggtccc tgctgagcag
      601 catctacttc ctgctgatgg tctttgtgga gttacccctg ctcctgagca tgctcagtgc
      661 tgtcctctgg gtgaccaggc ctcagagatg ctttgggaga ggtgaaaatg acctggtgaa
      721 gacccatagt cctgttgcct aggatagaga gaaacagttc ccaagaaatg gaaaataatc
      781 tctgtctctc tgttgtctct gtctctgtct ctggggtgta tgtatgtgtg tgcatgcacc
      841 ttgccggggc agatgtgtat gtgggagaca tctactggaa tcattccctt agtatctgag
      901 acagggtttc taattgacca gcacctttgt gtggtaggtc agacagctgg ccagggaact
      961 ccagggatct ccctgcctct accatccatc ctgagattgc aagcatacac gagtgcccta
     1021 gcttaaaaac aaacaaacaa acaaacacct taggttgtag ggattgaact catgtccttg
     1081 tacctgcaag gaaggtaggc gatttacctg ctgagccatc tccccaatct ggagaagact
     1141 caatctagta aagaacaact catcagcagt accatggctc tgatgtgctg cacaaccaga
     1201 ctcagactaa tcccactcct atagcaggga cagctgagtt ctggaaccca ttcatgtgcc
     1261 cctctctcag gacatcctgc aatacctatc tggggctatc ttccactgat gacttccaaa
     1321 gaagaaaata caagaaaaca tcacatttct tcttagtgta ctagttcctt agaggacaca
     1381 tgccaatata agactgcggg ccaccagcca gttgattgac caaatatctc ggtgatgtgg
     1441 cctcaccaag tagcataaag tttgccactg tcacactagc tatctgtccc ttattggcag
     1501 gacacaccct gctttctttt ttctcaacac agcccagtga ctaagcccat tgcaaaccca
     1561 gatggagtag ttgacctaag ctttgtacca cctgctcagg tcttcaagta gtagttaagc
     1621 cttggtccct gaaatctaga ttgctcagtg agaccaaatg gggaggtcaa ctgcaggaat
     1681 cagctgatct cacaggagtc acgaacccac atcaccccca aacccttcca ggaatggtct
     1741 cttcaccagg cccttccact ctctcccttt tactcagaca aatctattga atgtctaagt
     1801 agttatcact ctccacatac atgctccaaa ataagacaga cccaattaaa gtccatagag
     1861 aaggccaatg ggatcaaagg taaatactca ggggaaatga gtagtctcag cccaccagtc
     1921 tcagacatcc tgagttctgc accatgacac agtcttcttc ttgagtgggg ctctgacacc
     1981 cacagccaaa ttcacaacta acatgggtgt tctccaactt tgtggaagaa gagtccccag
     2041 gttagcatct tctcagtgat gacatgtgtt ggactctagt gagcttgcct cttgttaaga
     2101 ggatggtttt catttgcttc aggggtatac ctgccagtca gtcagccaca ttcccactca
     2161 tgctcagacc aacaatcatg gttaaactct gtgggacaca cacacacaca cacacacaca
     2221 cacacacaca cacacacgac atataatcag gagagggact cattagagcc tgtaggtcag
     2281 gcagtggtag cacatgcctt taatctcaac actcaggagg cagaggcagg tggatttctg
     2341 agttctaggt cagtctgctt tacagagtga gttctaggac tacacagaga aatccaaaaa
     2401 aacaaggcta cacagagaaa ccatgtcctg gggtaaaaaa
//
