LOCUS       NM_009846               1825 bp    mRNA    linear   ROD 31-JAN-2024
DEFINITION  Mus musculus CD24a antigen (Cd24a), mRNA.
ACCESSION   NM_009846
VERSION     NM_009846.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1825)
  AUTHORS   Dror,E., Fagnocchi,L., Wegert,V., Apostle,S., Grimaldi,B.,
            Gruber,T., Panzeri,I., Heyne,S., Hoffler,K.D., Kreiner,V.,
            Ching,R., Tsai-Hsiu Lu,T., Semwal,A., Johnson,B., Senapati,P.,
            Lempradl,A., Schones,D., Imhof,A., Shen,H. and Pospisilik,J.A.
  TITLE     Epigenetic dosage identifies two major and functionally distinct
            beta cell subtypes
  JOURNAL   Cell Metab 35 (5), 821-836 (2023)
   PUBMED   36948185
REFERENCE   2  (bases 1 to 1825)
  AUTHORS   Zhang,X., Yu,C., Liu,J.Q. and Bai,X.F.
  TITLE     Dendritic cell expression of CD24 contributes to optimal priming of
            T lymphocytes in lymph nodes
  JOURNAL   Front Immunol 14, 1116749 (2023)
   PUBMED   36969215
  REMARK    GeneRIF: Dendritic cell expression of CD24 contributes to optimal
            priming of T lymphocytes in lymph nodes.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1825)
  AUTHORS   Wang,X., Liu,M., Zhang,J., Brown,N.K., Zhang,P., Zhang,Y., Liu,H.,
            Du,X., Wu,W., Devenport,M., Tao,W., Mao-Draayer,Y., Chen,G.Y.,
            Chen,Y.E., Zheng,P. and Liu,Y.
  TITLE     CD24-Siglec axis is an innate immune checkpoint against
            metaflammation and metabolic disorder
  JOURNAL   Cell Metab 34 (8), 1088-1103 (2022)
   PUBMED   35921817
REFERENCE   4  (bases 1 to 1825)
  AUTHORS   Zhang,Y.F., Li,X.X., Cao,X.L., Ji,C.C., Gao,X.Y., Gao,D., Han,H.,
            Yu,F. and Zheng,M.H.
  TITLE     MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells
            Through Inhibiting Secretory Protein FAM19A1
  JOURNAL   Front Cell Neurosci 16, 866020 (2022)
   PUBMED   35685988
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1825)
  AUTHORS   Herranz-Perez,V., Nakatani,J., Ishii,M., Katada,T.,
            Garcia-Verdugo,J.M. and Ohata,S.
  TITLE     Ependymoma associated protein Zfta is expressed in immature
            ependymal cells but is not essential for ependymal development in
            mice
  JOURNAL   Sci Rep 12 (1), 1493 (2022)
   PUBMED   35087169
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1825)
  AUTHORS   Morse,H.C. 3rd.
  TITLE     Genetic nomenclature for loci controlling surface antigens of mouse
            hemopoietic cells
  JOURNAL   J Immunol 149 (10), 3129-3134 (1992)
   PUBMED   1431091
  REMARK    Review article
            Erratum:[J Immunol 1993 Mar 15;150(6):2563]
REFERENCE   7  (bases 1 to 1825)
  AUTHORS   Kato,K., Koyanagi,M., Okada,H., Takanashi,T., Wong,Y.W.,
            Williams,A.F., Okumura,K. and Yagita,H.
  TITLE     CD48 is a counter-receptor for mouse CD2 and is involved in T cell
            activation
  JOURNAL   J Exp Med 176 (5), 1241-1249 (1992)
   PUBMED   1383383
REFERENCE   8  (bases 1 to 1825)
  AUTHORS   Liu,Y., Jones,B., Brady,W., Janeway,C.A. Jr. and Linsley,P.S.
  TITLE     Co-stimulation of murine CD4 T cell growth: cooperation between B7
            and heat-stable antigen
  JOURNAL   Eur J Immunol 22 (11), 2855-2859 (1992)
   PUBMED   1385153
  REMARK    Erratum:[Eur J Immunol 1993 Mar;23(3):780. Linley PS [corrected to
            Linsley PS]]
REFERENCE   9  (bases 1 to 1825)
  AUTHORS   Hitsumoto,Y., Nakano,A., Ohnishi,H., Hamada,F., Saheki,S. and
            Takeuchi,N.
  TITLE     Purification of the murine heat-stable antigen from erythrocytes
  JOURNAL   Biochem Biophys Res Commun 187 (2), 773-777 (1992)
   PUBMED   1530634
REFERENCE   10 (bases 1 to 1825)
  AUTHORS   Liu,Y., Jones,B., Aruffo,A., Sullivan,K.M., Linsley,P.S. and
            Janeway,C.A. Jr.
  TITLE     Heat-stable antigen is a costimulatory molecule for CD4 T cell
            growth
  JOURNAL   J Exp Med 175 (2), 437-445 (1992)
   PUBMED   1346270
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK014279.1, AK133869.1 and AA154829.1.
            
            [WARNING] On Mar 11, 2024 this sequence was replaced by
            NM_009846.3.
            
            On Dec 22, 2005 this sequence version replaced NM_009846.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BG975994.1, AK133869.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                AK014279.1         2-63
            63-1811             AK133869.1         62-1810
            1812-1825           AA154829.1         410-423
FEATURES             Location/Qualifiers
     source          1..1825
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 23.01 cM"
     gene            1..1825
                     /gene="Cd24a"
                     /gene_synonym="Cd24; HSA; Ly-52; nectadrin"
                     /note="CD24a antigen"
                     /db_xref="GeneID:12484"
                     /db_xref="MGI:MGI:88323"
     exon            1..154
                     /gene="Cd24a"
                     /gene_synonym="Cd24; HSA; Ly-52; nectadrin"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..316
                     /gene="Cd24a"
                     /gene_synonym="Cd24; HSA; Ly-52; nectadrin"
                     /note="signal transducer CD24; R13-Ag; lymphocyte antigen
                     52; X62 heat stable antigen; M1/69-J11D heat stable
                     antigen; cluster of differentiation 24"
                     /codon_start=1
                     /product="signal transducer CD24 precursor"
                     /protein_id="NP_033976.1"
                     /db_xref="CCDS:CCDS23821.1"
                     /db_xref="GeneID:12484"
                     /db_xref="MGI:MGI:88323"
                     /translation="MGRAMVARLGLGLLLLALLLPTQIYCNQTSVAPFPGNQNISASP
                     NPSNATTRGGGSSLQSTAGLLALSLSLLHLYC"
     exon            155..1816
                     /gene="Cd24a"
                     /gene_synonym="Cd24; HSA; Ly-52; nectadrin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1793..1798
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Cd24a"
                     /gene_synonym="Cd24; HSA; Ly-52; nectadrin"
                     /note="putative"
     polyA_site      1811
                     /gene="Cd24a"
                     /gene_synonym="Cd24; HSA; Ly-52; nectadrin"
                     /note="putative"
ORIGIN      
        1 ccaccttgcc tgcgcccgcg cgagcttagc agatctccac ttaccgaaca tctagagagt
       61 cgcgccgcgc gccgacggag cggacatggg cagagcgatg gtggccaggc tagggctggg
      121 gttgctgctt ctggcactgc tcctacccac gcagatttac tgcaaccaaa catctgttgc
      181 accgtttccc ggtaaccaga atatttctgc ttccccaaat ccaagtaacg ctaccaccag
      241 agggggtggc agctccctgc agtccacagc tggtctcctg gctctctctc tctctcttct
      301 acatctctac tgttagagac tcaggccagg aaacgtctct acttccccat cttctacacc
      361 taccccaaat ggcaaccaca agtccaatgt gatcaggaag aaacaggtcc acctcgaatt
      421 ggctgttacc atatctcaac agaaaacacg gagaattcga aattcgacgg gattaaagga
      481 cgcgtgaaag gtttgagaga agagagatgc cgctattgaa tctgctggag ttttacatcc
      541 caagatgaag acagcattca gaattgatgt gatttccttg aatgtggctt aggaaatgtg
      601 gacacttaaa actctcactt gaaattgggc acaggtttga tgtagagata aggacggggt
      661 gcggaatgga gacccatttt gtcattgatt catctgaccg ataaggccat agtgcagtta
      721 ggtgatattc gaaagcttct ttgatgctct ttatgtatat gttggaagga actaccaggc
      781 gttgctttaa attcccaatg tgttgtttcg ttactactaa tttaataccg taagctctag
      841 gtaaagttcc atgttgttga actctgactg ttctctttgg aattgaacgt tttgcatcct
      901 cctcctgtgg ctttaggtct gacattgtat ttgaccttta ctagtaatta acatgtgcca
      961 ggcaatggtg gattggaacc catccccaag tccagccacc actgaataaa tctgatttca
     1021 aaagtcaaac agtagacatt tcccattgtc gtttctcact caccacaagc accaaattca
     1081 ctagagtaca ctggttccag agagcagaat catgttggcc ttggctaatt tcaaaatgct
     1141 gtcttttact ttggtatatg ttgagggctt ttcataattt aaagtgtgtt ctgttagcaa
     1201 ggcaaaaatt atgagtctta attctacagg caaatatgca aaggagccaa aactgtaaac
     1261 ccagcatttg ggatgtgaag actggaagct aactctcatt gaattcacaa agtcttttat
     1321 acaatttctg tacatacttt tttttttttt aagagaaaaa caaacggtgg atcagaatag
     1381 ccacgtttgg aatactttgg ttatccattc atatttttag atagttattg gtcctgtgcc
     1441 tgaaaggggg cttggttcta ccgtaagttt ttccaatttc cttgatatac acataccttc
     1501 taaaacctag acatttcctg aaaaaaatct tttgttcgca tggtcacaca ctgatgctta
     1561 cccgtacagt agtcttgata accagagtca ttttctccat ctttagaaac cttcctggga
     1621 agaaggagag ctcacagacc cgaagctact gtgtgtgtga atgaacactc cccttgcctc
     1681 acacctgaat gctgtacatc tatttgattg taaattgtgt ttgtgtattt atgctttgat
     1741 tcatagtaac ttctcatgtt atggaattga tttgcattga acacaaactg taaataaaag
     1801 aaagaaatgg cggagaaaaa aaaaa
//
