LOCUS       NM_027045               7500 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus coiled-coil serine rich 2 (Ccser2), transcript variant
            1, mRNA.
ACCESSION   NM_027045
VERSION     NM_027045.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7500)
  AUTHORS   Mun,D.J., Goo,B.S., Suh,B.K., Hong,J.H., Woo,Y., Kim,S.J., Kim,S.,
            Lee,S.B., Won,Y., Yoo,J.Y., Cho,E., Jang,E.J., Nhung,T.T.M.,
            Triet,H.M., An,H., Lee,H., Nguyen,M.D., Park,S.Y., Baek,S.T. and
            Park,S.K.
  TITLE     Gcap14 is a microtubule plus-end-tracking protein coordinating
            microtubule-actin crosstalk during neurodevelopment
  JOURNAL   Proc Natl Acad Sci U S A 120 (8), e2214507120 (2023)
   PUBMED   36795749
  REMARK    GeneRIF: Gcap14 is a microtubule plus-end-tracking protein
            coordinating microtubule-actin crosstalk during neurodevelopment.
REFERENCE   2  (bases 1 to 7500)
  AUTHORS   Nakano,Y., Wiechert,S. and Banfi,B.
  TITLE     Overlapping Activities of Two Neuronal Splicing Factors Switch the
            GABA Effect from Excitatory to Inhibitory by Regulating REST
  JOURNAL   Cell Rep 27 (3), 860-871 (2019)
   PUBMED   30995482
REFERENCE   3  (bases 1 to 7500)
  AUTHORS   Hosono,H., Yamaguchi,N., Oshima,K., Matsuda,T. and Nadano,D.
  TITLE     The murine Gcap14 gene encodes a novel microtubule binding and
            bundling protein
  JOURNAL   FEBS Lett 586 (10), 1426-1430 (2012)
   PUBMED   22673506
REFERENCE   4  (bases 1 to 7500)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   5  (bases 1 to 7500)
  AUTHORS   Kambouris,M., Triarhou,L.C., Dlouhy,S.R., Sangameswaran,L., Luo,F.,
            Ghetti,B. and Hodes,M.E.
  TITLE     Novel cDNA clones obtained by antibody screening of a mouse
            cerebellar cDNA expression library
  JOURNAL   Brain Res Mol Brain Res 25 (3-4), 183-191 (1994)
   PUBMED   7808216
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB871809.1, AK147383.1, CV556741.1 and BM214039.2.
            
            Transcript Variant: This variant (1) encodes isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147383.1, SRR1660821.49199.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 BB871809.1         15-20
            7-3202              AK147383.1         2-3197
            3203-3891           CV556741.1         147-835
            3892-7242           AK147383.1         3886-7236
            7243-7500           BM214039.2         2-259               c
FEATURES             Location/Qualifiers
     source          1..7500
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 21.29 cM"
     gene            1..7500
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /note="coiled-coil serine rich 2"
                     /db_xref="GeneID:72972"
                     /db_xref="MGI:MGI:101859"
     exon            1..223
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            224..1676
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     CDS             263..2764
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /note="isoform 1 is encoded by transcript variant 1;
                     granule cell antiserum positive protein 14; protein
                     FAM190B; granule cell antiserum positive 14; coiled-coil
                     serine-rich protein 2; serine-rich coiled-coil
                     domain-containing protein 2"
                     /codon_start=1
                     /product="serine-rich coiled-coil domain-containing
                     protein 2 isoform 1"
                     /protein_id="NP_081321.1"
                     /db_xref="CCDS:CCDS26948.1"
                     /db_xref="GeneID:72972"
                     /db_xref="MGI:MGI:101859"
                     /translation="MEEKTQIKTFLGSKLPKYGMKSVRSTLQPMPNGATVTLLGTSKS
                     SNVKSYIKNNGSDCSLSHSFNWRKTNKYQLGSQNTAELNNIQSTHDKLIEPEQHAPAP
                     GTLDGHGIKGGLKSASLFTSKLARPSTMFVSSAEELSQKSFSGPSNLGKFTKGTLLGR
                     TSYSSVNAKSHLNAFYGNRSSGNVQKPRVNSCASRSSSGESLAQSPDNAKSITCEKMV
                     RSQSFSHSIQNVFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLRSGMLTRSSLQS
                     EVLNGNEHVGFGFNRPYAAAGKKLALSNGPAVSSTLVYRMAHPPLLKSSRPPFSGPMT
                     VDSNKNPPADMCVEEEGMVSAQDSSPGKDQELIENESYRRDNDQTGKNESKVRYLSDD
                     VDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITPEEMTLKEEKHESRPSKDIFD
                     SPKESEQAFSKAEEWIDISVSDRSECTKHTSGNNLISPDTDYRAGSSFELSPSDSSDG
                     TYMWDEEGLEPIGSVHPVGSYESSEMNSIDILNNLESCDLEDDDLMLDVDLPEDAPLE
                     NVECDNMNRFDRTDRNVRQSQDGFWKRPPQRWSGQDHYHLSHPGHYHHHGQSDLSRGS
                     PYRESPLGHFESYGGTPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLK
                     RLLHQHDGSGSLHDVQLSLPSSPEPEDGDQIYKNEDLLNEITQLKEEIKKKDEKIQLL
                     EQQLATRCNCQQKSKEEKCTYADKYTQTPWRRIPGGYCAPSFSPWQGSFQGMPRTVPP
                     HRRQTSSTTAFQQPSQIYRPRPGKTNKATTYRGPQ"
     exon            1677..1873
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..1964
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            1965..2127
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            2128..2323
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            2324..2407
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            2408..2494
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            2495..2584
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            2585..2669
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     exon            2670..7496
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7465..7470
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /note="hexamer: AATAAA"
     regulatory      7472..7477
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /note="hexamer: AATAAA"
     polyA_site      7488
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
     polyA_site      7496
                     /gene="Ccser2"
                     /gene_synonym="1700012P13Rik; 2900054P12Rik; Fam190b;
                     Gcap14"
                     /note="major polyA site"
ORIGIN      
        1 ggcggagtcc aggagggtgc cggcctaggg agggggcgcg gcgtcggtga agtccggcgc
       61 tcccgcaggc cgaggaggcg atgctggctg ctgcggggca ggcggctgga cagaccggga
      121 tgtgacggaa ctgcctctcg cctctctccc atcctcgggc gggcaggtcg ctgggcgacc
      181 ggcagccggg ccgcggccga ggaggcaacg cgacctccgc acgattctgt caagttttaa
      241 gaaccaatgc accttatagc ccatggaaga aaaaacacaa atcaagacat ttttgggttc
      301 caagctgccg aaatatggaa tgaaatctgt gagaagtaca ttgcagccga tgccaaatgg
      361 cgccactgtg actttattag ggacctccaa gagtagtaat gtcaaaagtt acataaaaaa
      421 taatggctct gattgttcat tgtcccattc atttaattgg agaaaaacaa ataaatatca
      481 acttggttca caaaatacag cagaacttaa taatattcaa agtacacatg ataaactaat
      541 tgagcctgaa caacatgcac ctgctccagg aacgctggat gggcatggga taaagggagg
      601 tttgaaaagt gcttccttgt tcacatccaa gttagcaaga ccatcaacca tgtttgtgtc
      661 atcggcagag gagttaagtc aaaaatcttt ctctggacca tctaatttgg gtaaatttac
      721 caaaggcaca ttactaggaa ggacttcata ttcttcggtc aatgcgaagt cacatttgaa
      781 tgcgttttat gggaacagat cttctggtaa cgtgcagaag ccaagagtga actcctgtgc
      841 cagcagaagt agttctggag aaagcttagc acagtcccca gacaatgcta aatctatcac
      901 ttgtgaaaaa atggtaaggt cacaaagttt ttcacattcc attcagaatg tcttccttcc
      961 accttcatct ataaccagat cgcattcctt caacagagct gtagacctta caaagcctta
     1021 tcagaaccaa cagctccccg ttcgagtgcc tctccggtca ggtatgctaa caagaagttc
     1081 tctgcagtca gaagtactca atgggaacga acatgtgggg tttggtttta ataggcctta
     1141 tgctgctgct ggaaagaaac tggccttatc caatggcccc gctgtctcgt ccacgttggt
     1201 ttataggatg gctcatcccc ctctactgaa atctagccga cctccatttt ctgggcccat
     1261 gacagttgac agtaataaaa acccacctgc tgacatgtgc gtagaggaag aaggtatggt
     1321 ttcagcccag gacagctctc cgggtaagga ccaagaacta attgaaaatg aaagttaccg
     1381 aagagacaat gaccagactg ggaagaacga gtctaaagtt aggtacctga gcgatgacgt
     1441 ggatgatatt tccttgtcgt ccttgtcgtc ttccgacaag aatgatttaa gtgaagattt
     1501 cagcgatgat ttcatagact tagaggactc caacagaact agaataacgc cagaggaaat
     1561 gactctcaaa gaagaaaagc atgagagcag accatcaaag gatatatttg attctcctaa
     1621 ggaaagtgag caggccttca gtaaagctga agagtggata gatataagtg tctctgacag
     1681 gagtgaatgt acaaagcata catctggaaa caacttgatt tcaccggata cggattacag
     1741 agctgggtct tcatttgaac tctctccgtc cgatagctct gatggaacgt acatgtggga
     1801 tgaagagggc ctggagccca ttgggagtgt ccatcctgtt ggcagctatg agtcctctga
     1861 aatgaacagc atagatattc tgaataacct tgagtcgtgt gaccttgagg atgatgacct
     1921 tatgttggat gtggatttgc cggaggacgc acctcttgaa aatgtggagt gtgacaatat
     1981 gaaccgcttt gaccgaacag acagaaatgt acgacagtcg caggacggat tttggaaaag
     2041 gccaccccag aggtggagtg gacaggacca ttaccacctc agccaccctg gtcactatca
     2101 tcaccatgga caaagtgact tgagcagagg ctctccttat agagaatctc ctttgggtca
     2161 ttttgaaagc tatggaggga cccccttttt ccaggctcag aagatgtttg tagatgtgcc
     2221 cgacaacaca gtgatcctgg atgagatgac cctccggcac atggtccagg attgcacagc
     2281 tgtgaaaacg cagttactga aactcaagcg tctgttacac cagcatgacg gaagtggatc
     2341 attgcatgat gttcagctct cattgccatc cagtccagag ccagaagacg gtgatcagat
     2401 atataagaat gaagatttac taaatgaaat aacacaactt aaagaggaaa taaagaaaaa
     2461 agatgaaaaa atccaactat tagagcagca gcttgcaact cgatgtaact gtcagcagaa
     2521 atctaaagag gaaaagtgta catatgctga taaatatacc cagacaccct ggagacggat
     2581 tcctggtggg tattgtgcac cctccttctc tccttggcag ggctccttcc aggggatgcc
     2641 acggactgta ccgccgcacc gcagacagac ctcaagtact acagccttcc agcagccttc
     2701 ccagatctac agaccacgcc cagggaaaac taataaagcc acaacgtacc gaggcccaca
     2761 gtgactacac agttcaaggc gtgtgtccgg gtggtgcgca tccagatgga agctgtacac
     2821 atggcttgca acaggacaac agccgtggtt tgcaagagcg tccttcttcg tcaagcccgc
     2881 agttgacagt ggatgtggtg aagtacatac cttctgaaac ggacctgagc atgactctgg
     2941 atgctcaaga gcctcatcat ttggcagaga aaaaacctag tgacttgcag tttgtaactc
     3001 ctcctcctca gaccccttcc cagtcaagta cagtggacca gactaagagg ggtggaagaa
     3061 accaatgtcc tcagcccaag tccttgcagc ttttaaagcc atccaacttg agttctttga
     3121 cacctcctcc agattctgac tcctcaccaa gtagaacttc cacatgtaag aaggcaccag
     3181 gaatcacacc atgccattca aaacatcagc caacatcgaa tcaaaacaat cctgcaaatc
     3241 atttgaatct gaaaacgtct aaactccgtc ccccttctgg ctctttcaag caaaaacaaa
     3301 taagtaaccc ccaagtagag cctcagaact tccaggccaa gacaagcatc ccaaggccat
     3361 tagcacggcc aaaagagctg catgctccac acagcggttt gcattctggg gattgtgtgg
     3421 cctctaatcg atattctcgt cttcctaaac caaagataca ttaagtgcat agccatcacc
     3481 tgccaatttg ttttttgaaa acagtctgct ctctaatagc tttatgtgca gcttattact
     3541 atgttggagg ttccatttca gcaaatctta aaattaaaat gcagaagctt ctattagttt
     3601 ggttcttcca ttttgtatcc tggctgaatt acataccatt tgcacatact tgtctcaggt
     3661 aaacacaagt ttacttatcc atctcagagg cccaagtccc tcctcatgct atccagcctt
     3721 ctctctacat accagaaaag tcaaaatatt ccatgtatca ggcaggatgt gtacttggct
     3781 gatgtagtcc tgttgtggtt atcagaatct caccccgatg cttattcttc ttgtgagtat
     3841 ggctgctatt ttaactaaag attcaaagtg acggtggaag gtagctgtct gtaagcaggg
     3901 ttctggccag gttttgtgta tttaggaagt ctatgcaaaa ggtccccagt gaggaaagac
     3961 caggctttta gtgggggagt ccttagtagt ttcatctctc ctttctagga tcagtaatct
     4021 agtcctactg cttctccatt tatcagacaa attcccatgc tgacagttgt catattttat
     4081 gtaaaccagt tatatgttgc tgtaacatct tgttttacgt acacatttac tctttgctta
     4141 tattgctact gggtagattt ggagagctgg agatgcctat ggcatatcag ttgtaaactc
     4201 tgttggtgct agagttttgt gctggtaatt gagttttgaa tcttattaac ttatggatcc
     4261 atcatacttt caagtttcca taacatacat tggaaattta aaattataat aatatttgta
     4321 tttattgact ttttcctagt gtctgaagac tagaataatg gacttgaaat atttgcacaa
     4381 aattttgatg agatataaaa gagggtttta aagcttattt tctataaaaa atgagttaaa
     4441 acactttaag agaaatatat aaatttaaga ctatcataag tcactttttg ggtttcctaa
     4501 gtttctcttt tctgttggtg gaaggttgaa tgacagtttc ttgaaaagta gatttggggg
     4561 aaattaagtt gtaggtagga aagaatactt tcttaagaga gattgctcca gatgtcctat
     4621 ggaaggtagc tgtgggttaa gagagattgt tctagatgtg gctgtgggcc tccaagtgac
     4681 catgtacagg aacccagctg ggcttctggc aacttcacaa gcagttgagt gaatttacct
     4741 catgtttgcc caaatcatgc catctttagg ctggtcataa tttgtttaat tcatagtaag
     4801 atttctcaga aagataacct tacaagatca gtatctgatt agctgaccaa aaatgcatca
     4861 aaaggaatta tggccaaaaa aattaaatgt ctatggcttc ctttttaaat gtatctaggt
     4921 tacaaagaga aacgtggtat caagtgcatt agtgcaaagt tacaaagtca catttgctgc
     4981 ggtttggggg ggcggcagtc ttcccttaaa tgtcagaacc cctcatgtgg atttgtcttt
     5041 tggagaggca gacctttttc cagtttggga acagacgagc atagtctcac accacagcac
     5101 gttagtcaga ggaagctcag gacaggctgt gcatgggtta gacggtactg ggtcattgct
     5161 gctgtggcaa aagcacttat tcttccttca tgacagtgag ccaggttggc tacaggggta
     5221 tatgctttct ccttacggag aatgaaaacg aatctcatgt atcgcacatc agctacaatc
     5281 atactctatg ccctgcaata gaacatacta attaatgtat tagggttttg tttttttaat
     5341 tagagacttt tatagacttt atggaatact tctacaaatt ggtttatcct tgaaggaaag
     5401 ttttttaaaa tttatttata acccacttgt ctgagggaaa tgtctttgtt gtctgttttg
     5461 ttacagtgtt gactccaata atttctttat tctaatcttt ggcctacttt aattttttct
     5521 ccctgataaa tttgtagaaa tatttatcca gcagttcacc ctctctatac ctttgttggg
     5581 ccttagtctt aatagaagat agacagtctt atcaatatat tttgttctcc ttgagataag
     5641 agcctcacac aatgccaggc tggtctctaa taattcactg tgtagccaaa gatagccaaa
     5701 ggaattttga tctcctgcct ccttctcccg aatgctgaga ttacaggcgt gcaccaccac
     5761 acctggtttt gtgtggcact ggagacagaa tctagggctc agtgtgtgct ctgcaagcac
     5821 tctaccaagt gagctacact cccagccctc atgagtatgc ctttgcagca tactgtgtgc
     5881 ttcaaataca ctacccagag aaaatatcta ggatgcattc acaaataaca tagaccattg
     5941 gcctgcagtt ttctggaaaa gctgcaagga tatcaccttg tctgctccta gtaatagtaa
     6001 gcagtccaaa tgagggccca gcactgctga ataagcagag gtcatgttct ccacgtggct
     6061 cattctcttg cttgcgtgtg taaatcacat caactcacta ccaactgtcc tctgtgggaa
     6121 cgtagttcac tcaccctgtt ctgtcaggga agacagtggg agtaggtgaa gtctacgtcc
     6181 caagggtgag gttggttaat tttcacatgt atgaaagaga aaccaataca cagaattatt
     6241 tacttagctc tttaacagga tgtattaaaa aaaaaaaggc tgtttttttg agctagagtt
     6301 ttgcttggtg taagatcttc attggcatag gtatgggtga ttgcaagaca tccaacaaag
     6361 gactatagag ttgtattatt tggaagattt ctaaacactg agacttatct acctgttatt
     6421 tttcttttgg gtctcatttt ttattcgtgc agtattttca ggcacatcga ctactgctca
     6481 ctatatttat atagatgtta gggaactttc taagcatttt agtaagtaaa aatctgagta
     6541 tgaaagaaaa tatcagatac gcactttaaa tgagcttaat tgcttggagt cgtgcctgaa
     6601 atatcaaggt gcctcctctg ggtgtggctt ttgtttagta aaatgaattt ctctgcagtt
     6661 gttgctgttt gaaggtagct gtacagcttt tcacagaact gtatcccagc atgccacttt
     6721 gcccatgatc gcactaaatt ttccttgaat gtccatcatg cctttaaata ttttactcag
     6781 tgtatcaaga caacttgagc ctggtaatgt cacttctgag gttccgtgcc atagatggtg
     6841 ttccagatgc agggggcttc ctggctttcc accagagtgg tcctaccggt ttcctgaggt
     6901 tgcactttgg ggtccagtca gactgcagcc ccatctccac tctctccatc ctccacagta
     6961 gcttccatgt tgctgagtta gcttgggcaa ttacgtttgc atgcatgtgc acacagttga
     7021 aaatgaagtc tagccgtaat ataaacacat gggatttgcc ttggagatga tcacctgctc
     7081 ttttcctcat tcgaatgctt gagttctgtt ttctgttggt ctttccacag gtccctttaa
     7141 ctttctgctg cagcaatttg agaggatgta tttgaacaaa tgattatgag gttcctctaa
     7201 ttatgtaatt gattaaagat tgtgtcttca ccttgttgaa taaaagctgc ccctttcttc
     7261 ctggtagagc attgccacga tgagccaggc tggccttgag aatctggtca tggccgacta
     7321 aaaccagaaa cagtatctgt agtgttctcc ccccattgat tgtacaatcc agttcagagt
     7381 acataatgta tattagaatt tgcttgtaaa atgaattatg gaaaccggat gtaaagtctc
     7441 tttcctgaaa gtgttggctt agtaaataaa aaataaagtt cataattata aaagtgaaaa
//
