LOCUS       NM_001379289            3186 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus centriole, cilia and spindle associated protein
            (Ccsap), transcript variant 1, mRNA.
ACCESSION   NM_001379289 XM_030243802
VERSION     NM_001379289.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3186)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK086180.1, AK006786.1 and AC147266.6.
            
            On Mar 28, 2020 this sequence version replaced XM_030243802.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024705.1, AK086180.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-250               AK086180.1         64-313
            251-1048            AK006786.1         1-798
            1049-3186           AC147266.6         155164-157301       c
FEATURES             Location/Qualifiers
     source          1..3186
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 72.22 cM"
     gene            1..3186
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /note="centriole, cilia and spindle associated protein"
                     /db_xref="GeneID:73420"
                     /db_xref="MGI:MGI:1920670"
     exon            1..374
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..817
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /codon_start=1
                     /product="centriole, cilia and spindle-associated protein"
                     /protein_id="NP_001366218.1"
                     /db_xref="GeneID:73420"
                     /db_xref="MGI:MGI:1920670"
                     /translation="MSPGSGVKSEYMKRYREPRWDEYAPCYRELLRYRLGRRLLEQAH
                     APWLWDAWGPDSPSDSSASPSPAPRGALGEPSAPSAREEEQPVGERGAELRDAEEQDT
                     VLPAPPKKDTEEKPEEHKTKETDGAPSGPGPRQQPSALCARGSKKATRSPQRSTSKIK
                     ENKHPFALYGWGERQMDMGSQKTHNVCASASVHEIHESALRAKNRRQVEKRKLAAQRQ
                     RAHSVDVEKNQRVKPASAENPWLTEYMRCYSARA"
     exon            375..640
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            641..3186
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2298..2303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2328
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /note="major polyA site"
     regulatory      3062..3067
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3091
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
     regulatory      3110..3115
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3129
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
     regulatory      3164..3169
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3186
                     /gene="Ccsap"
                     /gene_synonym="1700054N08Rik"
ORIGIN      
        1 gagtccgtcg cacccgtagg cggcagcgcg gagcaggcag tcggcggcgc gcggcaccat
       61 gtccccgggc agcggggtga agagcgagta tatgaagcgc tatcgggagc cgcgctggga
      121 cgaatacgcg ccgtgctacc gcgagctgct gcgctaccgc ctgggccgcc ggctgctgga
      181 gcaagcgcac gcgccctggc tctgggacgc ctggggcccg gacagcccct cggacagctc
      241 ggcttcaccc agtccggccc ccaggggcgc gttaggggag ccctcggcgc cctccgcgcg
      301 ggaggaggag cagccggtgg gggagcgcgg cgcggagctg cgggacgcgg aggagcagga
      361 cacagtgtta ccagcaccac caaaaaagga cacggaagag aaacccgaag aacacaagac
      421 aaaagagact gatggggcac ccagtggccc tggaccgcgg caacagccta gtgccttatg
      481 tgccagagga agtaagaaag ccaccagaag cccacagaga tcgacgagca agataaaaga
      541 gaacaagcac ccgtttgctc tttatggctg gggagagaga cagatggaca tgggaagcca
      601 gaagacacac aacgtctgcg cgtcagcctc tgtgcacgag attcatgaat cagcacttcg
      661 agccaagaat agaagacagg tggagaaaag gaagctggct gcccagaggc agcgggctca
      721 ctcggtggac gtggaaaaga accagagggt aaagccggcg tctgccgaga acccatggct
      781 gacagagtat atgcggtgct actcagcgag ggcgtagccc cggggccatc ctctttcgag
      841 tgttcacaca agaaaaggaa aacaaagact ggcaactgag accacacacg ggtggaagaa
      901 accaactgtt cctgcaagcc cctccccctt aggaaattcc aagagatggt tttgctctca
      961 tgatggttgg tcacctgcct tagtagtggg acagaccatg gaagccatag atgctggctt
     1021 gtttatgaag acaagtcccc aagtcttgat attcttgtaa gagtttttat tgtaaagatt
     1081 ttgctctttg gagataccca caccgagtgc ctttaaccgg ctctaggcgc ttcccaccca
     1141 cccctcctgt agtccagtca gagctgctct ttttcatcag ctccacattc cacagctggc
     1201 agggtgtcct gtccactgtt caggactcac cgtgcagttc gccatgcacg gagccaagga
     1261 aggcaggtat ggagatccgg gctgttctga aaagccagag ctttggcggc tgcggaccga
     1321 ttacacttga taggttttgt ttcatctcgt cttcatatag acagtgagac ttcaggattt
     1381 tctggccaga gcgagggtca ccttttctcc ctaagtcatc ccttagacgt tcatttaatg
     1441 catagtttaa tagttctgga acattccagt gagcgacacg cagagagcat gttcagagca
     1501 acgatgacgt ttcttttgag tcactttcct ttaactgcag ttggctgctt aagtctgacc
     1561 gccattcctc tcttctaaga gagatagcgg atgaagatat tgagaagttg taatctgcag
     1621 tgacatttaa tgaactgggt ttgtttggcc tgtggggatg ggaccagcag acaccgttag
     1681 ggtgtccttg cctgcatcat gccctccttt tacagaactt aatgacggct ttgtgcacag
     1741 tgctgatggt ctaggttgaa aacctggctg cttgatcgct ggcccgatga tctttgctgc
     1801 catactgtgg gagaatttcg ggcaggtgct ggcctgatgg taatgttcgt tcttccttta
     1861 atagggaacc actgtcaggg ttttaaaaaa gaggttttaa agaacacgtg tttccgtgag
     1921 atgggtgcct tggccgccgt gcagaagaga ctcccagaag gatgagcacc gtgttcttct
     1981 ggagagatgg ggagctcttt tgcctgcacc cacgcagctt ctgagcctgc tgggtaagac
     2041 ccagtgttgg gtgtgtggct gagcattccc gtgatatttt tactttgggt tcttgagtat
     2101 gataatttct agaatgcaga ctgacttcat tccacgtgag actgtcacac gatgtcatct
     2161 gaaaactgta tcaagctttg aaaatgcaca ctaaagaatt ttttttttct aaaaaaaaaa
     2221 accactttta aaatatttgc ctagttttgt acagtcccca ttcatgtaca gagccctccc
     2281 tctgaggtgt atatttaatt aaagagtaag ttctacatgt tgtccaaata cagccttgct
     2341 agtgataact gtgttaacta catagtcccc aaatgttgcg taatcagggt gattggcaca
     2401 gtagcccagg ttgttgagaa tcactctttg taaagccatg ccttgaaagc ctgcattccc
     2461 tacatcgtca aacagcaccc ggcaatctca gaaagacagg tgggggaggg acacaggacc
     2521 ccccccaacc ctggccatca gacttgctca gaaaacagat gtgcatcctt ttgcatacgt
     2581 gtgtagaagt gcaggccggg gtgtgctgag atgcctggtg gtgtctttac caaattaccc
     2641 gcccctcccc ttctcagaac agggtttgtc tgtgtagccc tggctgtcct ggaactctgt
     2701 agaccaggct ggcctcgaac tcagagatcc gcttgcctct gcctcccaag cactgggatg
     2761 aaaggcatgt gccgcattct ttttacacag agcacaaacg atcaggactt tggagaacat
     2821 tcaatgttca tacctcgcaa ataaagtcag tatgaattag tggtgactcc ccacacctga
     2881 gtccctaatg tttagggttc aaattttctc ctttaaaaaa gacggtgatt actttttgaa
     2941 cctatgagaa ttttaattaa ttgattttaa ctttttccta ttctaggagc agtgaaataa
     3001 tttaaaatta acttctatgc tggaaacatc tgaaaatgtt tgagaatcca gtcatattta
     3061 aaataaacga catacaagtc ttttttaaaa acctgatttt aaggtcttaa ttaaaaccgt
     3121 tttctgtaag cgttttcatt ttctgtgcta cttttacttg agaattaaac agaatattga
     3181 actaaa
//
