LOCUS       NM_007721               1725 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus C-C motif chemokine receptor 10 (Ccr10), mRNA.
ACCESSION   NM_007721 XM_894898 XM_905316 XM_983479
VERSION     NM_007721.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Chang,C., Sell,L.B., Shi,Q. and Bhat,M.A.
  TITLE     Mouse models of human CNTNAP1-associated congenital hypomyelinating
            neuropathy and genetic restoration of murine neurological deficits
  JOURNAL   Cell Rep 42 (10), 113274 (2023)
   PUBMED   37862170
REFERENCE   2  (bases 1 to 1725)
  AUTHORS   Dhanushkodi,N.R., Prakash,S., Quadiri,A., Zayou,L., Srivastava,R.,
            Tran,J., Dang,V., Shaik,A.M., Chilukurri,A., Suzer,B., Vera,P.,
            Sun,M., Nguyen,P., Lee,A., Salem,A., Loi,J., Singer,M.,
            Nakayama,T., Vahed,H., Nesburn,A.B. and BenMohamed,L.
  TITLE     Mucosal CCL28 Chemokine Improves Protection against Genital Herpes
            through Mobilization of Antiviral Effector Memory CCR10+CD44+
            CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the
            Infected Vaginal Mucosa
  JOURNAL   J Immunol 211 (1), 118-129 (2023)
   PUBMED   37222480
  REMARK    GeneRIF: Mucosal CCL28 Chemokine Improves Protection against
            Genital Herpes through Mobilization of Antiviral Effector Memory
            CCR10+CD44+ CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells
            into the Infected Vaginal Mucosa.
REFERENCE   3  (bases 1 to 1725)
  AUTHORS   Davila,M.L., Xu,M., Huang,C., Gaddes,E.R., Winter,L.,
            Cantorna,M.T., Wang,Y. and Xiong,N.
  TITLE     CCL27 is a crucial regulator of immune homeostasis of the skin and
            mucosal tissues
  JOURNAL   iScience 25 (6), 104426 (2022)
   PUBMED   35663027
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1725)
  AUTHORS   Wang,J., Gong,J., Yang,Q., Wang,L., Jian,Y. and Wang,P.
  TITLE     Interleukin-17 Receptor E and C-C Motif Chemokine Receptor 10
            Identify Heterogeneous T Helper 17 Subsets in a Mouse Dry Eye
            Disease Model
  JOURNAL   Am J Pathol 192 (2), 332-343 (2022)
   PUBMED   35144761
  REMARK    GeneRIF: Interleukin-17 Receptor E and C-C Motif Chemokine Receptor
            10 Identify Heterogeneous T Helper 17 Subsets in a Mouse Dry Eye
            Disease Model.
REFERENCE   5  (bases 1 to 1725)
  AUTHORS   Zhao,L., Hu,S., Davila,M.L., Yang,J., Lin,Y.D., Albanese,J.M.,
            Lo,Y., Wang,Y., Kennett,M.J., Liu,Q. and Xiong,N.
  TITLE     Coordinated co-migration of CCR10+ antibody-producing B cells with
            helper T cells for colonic homeostatic regulation
  JOURNAL   Mucosal Immunol 14 (2), 420-430 (2021)
   PUBMED   32773769
  REMARK    GeneRIF: Coordinated co-migration of CCR10(+) antibody-producing B
            cells with helper T cells for colonic homeostatic regulation.
REFERENCE   6  (bases 1 to 1725)
  AUTHORS   Bhat,M.A., Rios,J.C., Lu,Y., Garcia-Fresco,G.P., Ching,W., St
            Martin,M., Li,J., Einheber,S., Chesler,M., Rosenbluth,J.,
            Salzer,J.L. and Bellen,H.J.
  TITLE     Axon-glia interactions and the domain organization of myelinated
            axons requires neurexin IV/Caspr/Paranodin
  JOURNAL   Neuron 30 (2), 369-383 (2001)
   PUBMED   11395000
REFERENCE   7  (bases 1 to 1725)
  AUTHORS   Wang,W., Soto,H., Oldham,E.R., Buchanan,M.E., Homey,B., Catron,D.,
            Jenkins,N., Copeland,N.G., Gilbert,D.J., Nguyen,N., Abrams,J.,
            Kershenovich,D., Smith,K., McClanahan,T., Vicari,A.P. and
            Zlotnik,A.
  TITLE     Identification of a novel chemokine (CCL28), which binds CCR10
            (GPR2)
  JOURNAL   J Biol Chem 275 (29), 22313-22323 (2000)
   PUBMED   10781587
REFERENCE   8  (bases 1 to 1725)
  AUTHORS   Jarmin,D.I., Rits,M., Bota,D., Gerard,N.P., Graham,G.J.,
            Clark-Lewis,I. and Gerard,C.
  TITLE     Cutting edge: identification of the orphan receptor
            G-protein-coupled receptor 2 as CCR10, a specific receptor for the
            chemokine ESkine
  JOURNAL   J Immunol 164 (7), 3460-3464 (2000)
   PUBMED   10725696
REFERENCE   9  (bases 1 to 1725)
  AUTHORS   Zlotnik,A. and Yoshie,O.
  TITLE     Chemokines: a new classification system and their role in immunity
  JOURNAL   Immunity 12 (2), 121-127 (2000)
   PUBMED   10714678
  REMARK    Review article
REFERENCE   10 (bases 1 to 1725)
  AUTHORS   Nibbs,R.J., Wylie,S.M., Pragnell,I.B. and Graham,G.J.
  TITLE     Cloning and characterization of a novel murine beta chemokine
            receptor, D6. Comparison to three other related macrophage
            inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5
  JOURNAL   J Biol Chem 272 (19), 12495-12504 (1997)
   PUBMED   9139699
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK090044.1.
            
            On or before Sep 2, 2006 this sequence version replaced
            XM_894898.2, XM_905316.2, XM_983479.1, NM_007721.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090044.1, AF215983.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1725              AK090044.1         4-1728
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 64.34 cM"
     gene            1..1725
                     /gene="Ccr10"
                     /gene_synonym="C-C CKR-10; CC-CKR-10; CCR-10; Cmkbr9;
                     Gpr2"
                     /note="C-C motif chemokine receptor 10"
                     /db_xref="GeneID:12777"
                     /db_xref="MGI:MGI:1096320"
     exon            1..44
                     /gene="Ccr10"
                     /gene_synonym="C-C CKR-10; CC-CKR-10; CCR-10; Cmkbr9;
                     Gpr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1109
                     /gene="Ccr10"
                     /gene_synonym="C-C CKR-10; CC-CKR-10; CCR-10; Cmkbr9;
                     Gpr2"
                     /note="G protein-coupled receptor 2; chemokine C-C
                     receptor 9; chemokine (C-C motif) receptor 10"
                     /codon_start=1
                     /product="C-C chemokine receptor type 10"
                     /protein_id="NP_031747.2"
                     /db_xref="CCDS:CCDS25454.1"
                     /db_xref="GeneID:12777"
                     /db_xref="MGI:MGI:1096320"
                     /translation="MGTKPTEQVSWGLYSGYDEEAYSVGPLPELCYKADVQAFSRAFQ
                     PSVSLMVAVLGLAGNGLVLATHLAARRTTRSPTSVHLLQLALADLLLALTLPFAAAGA
                     LQGWNLGSTTCRAISGLYSASFHAGFLFLACISADRYVAIARALPAGQRPSTPSRAHL
                     VSVFVWLLSLFLALPALLFSRDGPREGQRRCRLIFPESLTQTVKGASAVAQVVLGFAL
                     PLGVMAACYALLGRTLLAARGPERRRALRVVVALVVAFVVLQLPYSLALLLDTADLLA
                     ARERSCSSSKRKDLALLVTGGLTLVRCSLNPVLYAFLGLRFRRDLRRLLQGGGCSPKP
                     NPRGRCPRRLRLSSCSAPTETHSLSWDN"
     exon            45..1725
                     /gene="Ccr10"
                     /gene_synonym="C-C CKR-10; CC-CKR-10; CCR-10; Cmkbr9;
                     Gpr2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1233..1238
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccr10"
                     /gene_synonym="C-C CKR-10; CC-CKR-10; CCR-10; Cmkbr9;
                     Gpr2"
                     /note="hexamer: ATTAAA"
     polyA_site      1256
                     /gene="Ccr10"
                     /gene_synonym="C-C CKR-10; CC-CKR-10; CCR-10; Cmkbr9;
                     Gpr2"
                     /note="major polyA site"
ORIGIN      
        1 agaaaccctt gtagccagag atggggacca agcccacaga gcaggtctcc tggggacttt
       61 actccgggta cgatgaggag gcctattcgg ttgggccgct gccagagctc tgttacaagg
      121 ctgatgtcca ggctttcagt cgggccttcc aacccagtgt ctccctgatg gtggctgtac
      181 tgggtctggc tggcaatggc ctagtcttgg ccacccatct ggcagccaga cgaactaccc
      241 gatctcccac ctccgttcac ctgctccagt tggccctggc tgacctttta ttggccctga
      301 ctttgccttt tgctgcagca ggggctcttc agggctggaa tctaggaagt accacctgcc
      361 gtgccatctc aggcctctac tcggcctctt tccacgctgg cttcctcttc ctagcctgta
      421 tcagcgccga ccgctatgtg gccatcgcac gagctctccc agccgggcag cggccctcaa
      481 cgcctagccg agcgcacttg gtttcagtct tcgtgtggct gttgtcgctg tttctggctc
      541 tacctgcgct ccttttcagc cgggacgggc cacgtgaagg ccaacgacgc tgtcggctca
      601 tttttcccga aagcctcacg cagactgtga aaggggcaag cgcagtggcg caggtggtcc
      661 tcggcttcgc gctccctctg ggcgtcatgg cagcctgtta tgcgctcctg ggccgcacgc
      721 ttctggccgc cagggggcca gagcggcggc gtgcactgcg cgtcgtggtg gctttggtgg
      781 tggccttcgt ggtgctgcag ttgccctaca gccttgccct gctgctggat acagccgatc
      841 tactggcagc ccgcgagcgg agctgctcct ccagcaagcg caaggatcta gctttgctgg
      901 tcaccggcgg cttgaccctg gtccgttgca gcctcaatcc ggtgctttat gcctttttgg
      961 gcctgcgttt ccgccgggac ctgcggaggc tgctccaggg cggaggatgc agcccgaagc
     1021 ccaaccctcg tggccgctgc ccccgtcgac tccgcctttc ttcctgctct gctcctactg
     1081 agacccacag tctctcttgg gacaactagg gctacaattc cagagaaggg ggagggctaa
     1141 agaaacaatc ccagggaggg taatagaaag gggagtaagt agggggacgt tgagaaagac
     1201 ttcaggatct aaagagattg cctctgcgct taattaaatt gattctgtgc aaatgagatg
     1261 caacccaact actgttacta tttttgaatt accagctttg gttgcagcaa ggccaagaca
     1321 gtgggttaca ccccacgccc ctgcttgcgt ctcagtggga ggtgtgaagg gacaggggtt
     1381 gctgagtcgg ctaaagcttt gagtactgac acgccctatg cttcactcgg tctctgccaa
     1441 ccgaggtgag gtgggaaagc tgccaggtga ggaggggcgg ggtttctcct cgggagtcag
     1501 tgtaagaaag ggctttctaa taaccctatc gctatccagt agtggctgct ttagcaagta
     1561 cctagatccc agcgtgtgaa atgtatgggg tgatgctgtc cccagctgta cgtgcgtggg
     1621 tctggtagag gctggaggca agagattcta gtttggggta ggtttttgga tcccttctaa
     1681 agtcctgctg tgcaaagaaa aacgctaatt aaaaagttga gtctg
//
