LOCUS       NM_026484               5776 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus cyclin Y (Ccny), mRNA.
ACCESSION   NM_026484 XM_905427 XM_919358 XM_919367
VERSION     NM_026484.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5776)
  AUTHORS   Seo,J., Hwang,H., Sohn,H., Cho,E., Jung,S., Kim,S., Um,S.M.,
            Kim,J.Y., Kang,M., Choi,Y., Kim,J.H., Kim,M., Kim,S.Y., Lee,S.K.,
            Ahnn,J., Rhim,H., Jo,D.G., Kim,E. and Park,M.
  TITLE     Cyclin Y regulates spatial learning and memory flexibility through
            distinct control of the actin pathway
  JOURNAL   Mol Psychiatry 28 (3), 1351-1364 (2023)
   PUBMED   36434054
  REMARK    GeneRIF: Cyclin Y regulates spatial learning and memory flexibility
            through distinct control of the actin pathway.
REFERENCE   2  (bases 1 to 5776)
  AUTHORS   Zhang,K., Da Silva,F., Seidl,C., Wilsch-Brauninger,M., Herbst,J.,
            Huttner,W.B. and Niehrs,C.
  TITLE     Primary cilia are WNT-transducing organelles whose biogenesis is
            controlled by a WNT-PP1 axis
  JOURNAL   Dev Cell 58 (2), 139-154 (2023)
   PUBMED   36693320
REFERENCE   3  (bases 1 to 5776)
  AUTHORS   Da Silva,F., Zhang,K., Pinson,A., Fatti,E., Wilsch-Brauninger,M.,
            Herbst,J., Vidal,V., Schedl,A., Huttner,W.B. and Niehrs,C.
  TITLE     Mitotic WNT signalling orchestrates neurogenesis in the developing
            neocortex
  JOURNAL   EMBO J 40 (19), e108041 (2021)
   PUBMED   34431536
REFERENCE   4  (bases 1 to 5776)
  AUTHORS   Molinas,A., Heil,S. and Koch,S.
  TITLE     The Candidate IBD Risk Gene CCNY Is Dispensable for Intestinal
            Epithelial Homeostasis
  JOURNAL   Cells 10 (9), 2330 (2021)
   PUBMED   34571979
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5776)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 5776)
  AUTHORS   Shalom-Barak,T., Zhang,X., Chu,T., Timothy Schaiff,W., Reddy,J.K.,
            Xu,J., Sadovsky,Y. and Barak,Y.
  TITLE     Placental PPARgamma regulates spatiotemporally diverse genes and a
            unique metabolic network
  JOURNAL   Dev Biol 372 (1), 143-155 (2012)
   PUBMED   22967998
REFERENCE   7  (bases 1 to 5776)
  AUTHORS   Mikolcevic,P., Sigl,R., Rauch,V., Hess,M.W., Pfaller,K.,
            Barisic,M., Pelliniemi,L.J., Boesl,M. and Geley,S.
  TITLE     Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin
            Y and is essential for spermatogenesis
  JOURNAL   Mol Cell Biol 32 (4), 868-879 (2012)
   PUBMED   22184064
  REMARK    GeneRIF: CDK16 isolated from testis was unphosphorylated,
            interacted with CCNY, and exhibited kinase activity.
REFERENCE   8  (bases 1 to 5776)
  AUTHORS   Jiang,M., Gao,Y., Yang,T., Zhu,X. and Chen,J.
  TITLE     Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1
  JOURNAL   FEBS Lett 583 (13), 2171-2178 (2009)
   PUBMED   19524571
REFERENCE   9  (bases 1 to 5776)
  AUTHORS   Collins,M.O., Yu,L., Coba,M.P., Husi,H., Campuzano,I.,
            Blackstock,W.P., Choudhary,J.S. and Grant,S.G.
  TITLE     Proteomic analysis of in vivo phosphorylated synaptic proteins
  JOURNAL   J Biol Chem 280 (7), 5972-5982 (2005)
   PUBMED   15572359
REFERENCE   10 (bases 1 to 5776)
  AUTHORS   Lluch Fernandez,M.D., Pena Grinan,M.J., Perez Cano,R., Ramos
            Sanchez,I. and Montoya Carcia,M.J.
  TITLE     [Phosphorus-calcium metabolism in children under long-term
            anticonvulsant therapy]
  JOURNAL   An Esp Pediatr 35 (2), 103-107 (1991)
   PUBMED   1952457
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK014201.1, AK028696.1, AK014507.1, AC108777.7 and AW048376.1.
            
            On Oct 28, 2017 this sequence version replaced NM_026484.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK028696.1, SRR10223970.19774.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 AK014201.1         2-5
            5-4021              AK028696.1         2-4018
            4022-4402           AK014507.1         845-1225
            4403-4403           AC108777.7         211805-211805       c
            4404-5757           AK014507.1         1227-2580
            5758-5776           AW048376.1         1-19                c
FEATURES             Location/Qualifiers
     source          1..5776
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 4.91 cM"
     gene            1..5776
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="cyclin Y"
                     /db_xref="GeneID:67974"
                     /db_xref="MGI:MGI:1915224"
     exon            1..637
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             484..1509
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="cyclin fold protein 1"
                     /codon_start=1
                     /product="cyclin-Y"
                     /protein_id="NP_080760.2"
                     /db_xref="CCDS:CCDS29050.1"
                     /db_xref="GeneID:67974"
                     /db_xref="MGI:MGI:1915224"
                     /translation="MGNTTSCCVSSSPKLRRNAHSRLESYRPDTDLSREDTGCNLQHI
                     SDRENIDDLNMEFNPSDHPRASTIFLSKSQTDVREKRKSLFINHHPPGQTSRKYSSCS
                     TIFLDDSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPD
                     YDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLG
                     AILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYF
                     DLRSLAEANNLSFPLEPLSRERAHKLEAISRLCEDKYKDLRKPMRKRSASADNLILPR
                     WSPAIIS"
     exon            638..712
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            713..747
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            748..848
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            849..884
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            885..942
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1062
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1229
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1392
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..5761
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2099..2104
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2120
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="major polyA site"
     regulatory      3659..3664
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      3678
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="major polyA site"
     regulatory      4002..4007
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4023
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="major polyA site"
     regulatory      5737..5742
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="hexamer: AATACA"
     polyA_site      5761
                     /gene="Ccny"
                     /gene_synonym="1700025H17Rik; 3110050L10Rik;
                     4631402G10Rik; 5730405I09Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggcgtgggg ccgggctcgc gaaccccagc cgcacgccac ggttgtcgtg caacgctgcg
       61 gacgctcccg ctaactgcgg tccggtctgc gtatccgcgc gcactcgcgt gtccccggcg
      121 tgaaccggaa ccgcttgcgg aagtcgccgc tgggagcgga gcgctgaaca agaacacggt
      181 gggaggcggc ctgcgcggcg ccacccgcca tggccgcggc ggggtgagca ctgcgtgggg
      241 ccgcagtcgc ggactcgggc tcctccgccg caaaccaggg gctgaggccg tagcagctgg
      301 ggtcgctgtc tgtcggtagc tgtagccgcc tgcacgtcgt cgccgtccat ggcgcggccc
      361 cgccgccgcc gtcgctgctg acccgggccc ggagcggttt ccgccctcca cggggcgcgg
      421 gcggcctgcc tttgcgcccg agcctgcgcc cgcgccccgg ggctaccggt cgggtagtca
      481 gcgatgggga acacaacttc gtgctgcgtg tcgtccagcc ccaagctccg gaggaatgcg
      541 cactcgcggc tggagtccta ccgcccggac acggacctca gccgtgagga cactggctgc
      601 aatctgcagc acatcagcga ccgggaaaac atcgacgatt taaacatgga attcaatcct
      661 tcagaccatc ctcgggccag cacaatattc ctcagcaaat ctcagacaga cgtgagagaa
      721 aaacgcaaga gtctcttcat taaccatcat cctccagggc agacatcaag gaaatacagc
      781 tcttgctcca ccatcttcct agatgacagc acagtcagcc agccaaacct caagtacacc
      841 atcaaatgtg tagctcttgc gatatattac cacatcaaaa acagggaccc agatggaagg
      901 atgctcttag atatttttga tgaaaacctc caccctcttt cgaaatccga agtgccacct
      961 gattatgaca aacacaaccc agaacagaag caaatttacc ggttcgttcg gacactcttc
     1021 agtgctgctc agctgacagc tgaatgtgcc attgtcaccc tggtatacct tgaaaggctc
     1081 ttgacatacg cagagattga tatctgtcca gccaattgga agcgcattgt tctaggggca
     1141 atcctgctgg cctctaaggt gtgggatgac caagctgtgt ggaatgtgga ttactgccag
     1201 atcctgaaag acatcacagt ggaggacatg aatgaactgg agaggcagtt tcttgaattg
     1261 ctacagttta acatcaatgt tccttccagt gtgtatgcca agtattattt tgatcttcgt
     1321 tctctggcag aagcaaacaa cctgagcttt cctctggagc ccctaagcag agagcgtgcc
     1381 cacaagcttg aggccatctc tcgtctctgt gaggacaagt acaaggacct gaggaaaccc
     1441 atgaggaagc gttcagcaag tgctgacaac ctgattctgc caaggtggtc tccagccatc
     1501 atctcctaac tggggcactc tcctgaggct gtgctgtccc tcagtttctc cttttgttta
     1561 aagaaaagat gaacttgggt ggttttgttt ggtttggttt tcttttttcc ttctgttttt
     1621 aacaatagcc tcatcgaggc tgccttcagc ccgcctccac acttggtggg tgcacgcaga
     1681 gcggctttaa gggacgtgaa atcagtattc aggaaacttg gtgtcaagcc ttcccggcca
     1741 tcatgaaaag cacttctttc atggaggaaa cagactctaa tcctggagaa ggaaatgaag
     1801 gaaaaggaag ttgtgttaag ggatagatta cttggtagct ttgctgtttc tgggtccttg
     1861 tctggtcata gataccagat ggagccagat gataggtagc agagttgaat gcatctccaa
     1921 atcgggaatg ccatgctatg cccttggaat ctgtgtgctc tgtaagaaag acttcctgca
     1981 ttccttcatg ctgctctcgg gattggggat ggggatgttt gttcattttt attctggttg
     2041 ggttttgatt cctcagagca gagagtatag tttgtaacca ccatggcaca gacatccaaa
     2101 taaatagtac tgattgttta tctctgctcc attttctcta gccttcttct gagctttctt
     2161 cctcacaagt aagatgtgct tgttgtgttt ctacacacct gttatatatg attctctttc
     2221 aacaatagca ggattaactt gactgtagta ctgaaccaaa actatccctc tcctgcctag
     2281 ttccaagaac attctatcta gattaatatg ggtgcttgtg ccttccagtt ttcttgcaat
     2341 tggttgttct tggttttggt tttgtcacct cctctccatc ccaggttctc tttttctgct
     2401 aacatgaagg tgtaattaca aaacgcactc agactttgtg gctgaaggca aaggtcctca
     2461 gcacaagcat cttggataga gaagcatccg gggagccagg tttccctgac ctcatgagga
     2521 gccatgtcca tgtgctccct gcctggtcat tcttctactt ccatgtccat tgttgtaagc
     2581 aatattctcc ttgaatttta tatgcttcct ttaaatcaaa tttagtctat ttgtatacaa
     2641 tttttttaaa aatctaaaat ttagaaaatg gggagtgggt gggtgggtat ccagtgggaa
     2701 gatcactaaa aggaaaaatg ttactatttc ctgaggtatt tttcacagaa tgattgaata
     2761 aaaaaaaaaa ttcaacttgc attctcattg tgggtgcttg gagaagctac acaaactgtg
     2821 aaggttcata cttccttact tataaccagc ttttgtgttt tctgactggt tttggcttgt
     2881 ttggggaata gattaaactc ttctattgag tgcagtaaaa gggttagagg tagctatcaa
     2941 agagagagtc tgacatgaag tctaagagtc tgagtcacac acaagtgctt tgcttctgcc
     3001 catcttaggt tgcggtgacc gaggtttgtg aggttttcct tgtttgagat aaattctagc
     3061 atttgcttta tcatatactc ctcctgtgtg agcgtggaaa agtttagaat tgtatgctag
     3121 ttttgaatgc cctaaaatca tatgcctgac ccctctcaat agagcacact ttgaagatgg
     3181 aaggaacaaa atatcaaaat cccaaaagta tgaagccaca aatgttagta aagagtcagt
     3241 gcagttcttg tgcagttttg gatgcaatat gagcaaattc tagcctaaac ttgcaaagca
     3301 ggaagtaaaa aattaactac cctcctgttg cctctttgat gatttgctct gagtgggaaa
     3361 ggggatcggc ttctctcctt acaaacctta aacagaggtc gaaacatgta gaaagtgtca
     3421 ttttgtattc cctcatctct ataactctag aagggaccta ttttcttagc caaatatgaa
     3481 tgcctcttag atgaatcctt cctctcatgt aaagtacctt atcttaccag cccatttcag
     3541 gaaagaactg ctggcttgat agcagaaatc ttatttttat tccttttatt tgaatgggag
     3601 atttggaaat tgacttatgt aaatagttca atgcacctga tactattttg tggagtttat
     3661 taaactactt taaaagattg tacagtgtat tcgttgtatg tgtgtacaca cagtctggta
     3721 cctgacattc aacagtgact ctttatagcc tggcttggtt ttattcagac tgttgactat
     3781 tgttttcaag ccttgtacac tggactctac ctctgaatag gaaggttttc tctttgcatc
     3841 agtgagtgtt aactgtatta attggttgta tttcttgcac taaggatttc agttgtactg
     3901 tttagtctga attactaggc atgtaagtat aggctcattt aatttttcta tacaataatg
     3961 aaaacttatt tttgttttct gggttgttct caggttgcca aaataaaaag gagataaaac
     4021 caatctaata gtagtgttga taaatcatag tgactgtaac ttgtttgcaa agtagttcgg
     4081 tgtccaacag gtaacgctgg atgctgtttg ggaatgctat ctcagtgcag cctctggtaa
     4141 agagctcgtt gtcattgttg aaggatgaag aaagccacag ttttttgact atagacttga
     4201 tttaaacagc aaatataatt tgttgaagaa taaacacaca ttccggtaaa ttttgtttta
     4261 ctttttcact gggaaaagaa aggagttaag ctaaaatata atgagatcct aagcacctaa
     4321 gaggtgcttt catgccttaa tgttcaggtg agatcagctg tgacttcatg cctccagctg
     4381 tttaagatag ctcttctgtt ctgtgttcct tctccatggt ctttacctgg gatatctcca
     4441 acttggtgtt tcccttgctt cagggaattt tgctgcttac ctgagtgtca aagcagaatt
     4501 tggtgagtta tgattttgca tattcttgct gctttaggga cagcaacctg gggccatatt
     4561 ataagctttg agtttatata tgtatatatt cttagttcac tataggtatt taataagtta
     4621 aaaatatata tgtacataga acaaatactg tctgccttcc tgctatattt ttttaattat
     4681 ggtggtataa gattggacag tgttttcaga gtggcaatac tgaatcatga ttgtgaggct
     4741 ggcctcctag tctatgtaat catattctgc ctcaaaacag taaaattgag caggttttag
     4801 gggtgatgag taaatgaatt ctaagaatag tgagagaaag tgtgtatgtc ttcagtgatt
     4861 gagaaactga agcccacctg ggacttcagc caggtgagga gctaagttag ccagtaggaa
     4921 tcagagcaca ttctttcctt aaatactgtt tctgtgttat aaaccactat gtcctggtcc
     4981 tcagtggagt ggatatctca agactgagcc ttggcagttc ttacaaacat gaatggtctt
     5041 ctgaaaagca agctacagat gatgcctatc cttgttaata ggaggaaata ggaagcatag
     5101 cctggagcag aactggggaa agaacttagc ttagggctaa gaacccctca gctctatgcg
     5161 tagaaagaaa actccagcct ataataggaa taacagttca gccttactga atgcagagca
     5221 cagagcagca ccagaatgcc ctcccagaag caagctacct gacagctcca ttagagacaa
     5281 ggaagtcagt gaggcgtgtg ctcacactgc tgatgacttc aacaagccat accccatgct
     5341 acttgttaga gcttcttact gagtttgtat atgtcaaggc cacagatcct ctggtgccac
     5401 ttttactaga aacttcttcg gtaagcaata caaaaatgac tacttttact gatggtgtgt
     5461 cattagaagc tgctttgtgt gtacactgct gcagggttag caatgcccaa gccaggactt
     5521 gttccaaaaa aacatgtaga gttctccaag aacctgttta tactaagaaa tgccctccaa
     5581 catgtctgac tgaatggcat ttgagattta taggtcctag taaaccatct tgtatccttt
     5641 tgtgatttgt ttgtgggcag ggaactttat tccttttgag aacttttgtt tataaataga
     5701 tttaaatgtg caatcaaaaa ctgtcatctc aaaataaata cagttttgac aaaaatgtta
     5761 aaaaaaaaaa aaaaaa
//
