LOCUS       NM_009831               3418 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus cyclin G1 (Ccng1), transcript variant 1, mRNA.
ACCESSION   NM_009831
VERSION     NM_009831.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Strasser,A.S., Gonzalez-Reiche,A.S., Zhou,X.,
            Valdebenito-Maturana,B., Ye,X., Zhang,B., Wu,M., van Bakel,H. and
            Jabs,E.W.
  TITLE     Limb reduction in an Esco2 cohesinopathy mouse model is mediated by
            p53-dependent apoptosis and vascular disruption
  JOURNAL   Nat Commun 15 (1), 7154 (2024)
   PUBMED   39168984
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3418)
  AUTHORS   Lin,Y., Tang,W., Huang,P., Wang,Z., Duan,L., Jia,C., Sun,R., Liu,L.
            and Shen,J.
  TITLE     Denticleless E3 ubiquitin protein ligase (DTL) maintains the
            proliferation and differentiation of epidermis and hair follicles
            during skin development
  JOURNAL   Dev Dyn 253 (7), 635-647 (2024)
   PUBMED   38131461
REFERENCE   3  (bases 1 to 3418)
  AUTHORS   Katano,W., Mori,S., Sasaki,S., Tajika,Y., Tomita,K., Takeuchi,J.K.
            and Koshiba-Takeuchi,K.
  TITLE     Sall1 and Sall4 cooperatively interact with Myocd and SRF to
            promote cardiomyocyte proliferation by regulating CDK and cyclin
            genes
  JOURNAL   Development 150 (24) (2023)
   PUBMED   38014633
REFERENCE   4  (bases 1 to 3418)
  AUTHORS   Kuzelova,A., Dupacova,N., Antosova,B., Sunny,S.S., Kozmik,Z. Jr.,
            Paces,J., Skoultchi,A.I., Stopka,T. and Kozmik,Z.
  TITLE     Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell
            Proliferation and Photoreceptor Maintenance
  JOURNAL   Cells 12 (7), 1035 (2023)
   PUBMED   37048108
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3418)
  AUTHORS   Taguchi,K., Elias,B.C., Sugahara,S., Sant,S., Freedman,B.S.,
            Waikar,S.S., Pozzi,A., Zent,R., Harris,R.C., Parikh,S.M. and
            Brooks,C.R.
  TITLE     Cyclin G1 induces maladaptive proximal tubule cell
            dedifferentiation and renal fibrosis through CDK5 activation
  JOURNAL   J Clin Invest 132 (23), e158096 (2022)
   PUBMED   36453545
  REMARK    GeneRIF: Cyclin G1 induces maladaptive proximal tubule cell
            dedifferentiation and renal fibrosis through CDK5 activation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3418)
  AUTHORS   Endo,Y., Fujita,T., Tamura,K., Tsuruga,H. and Nojima,H.
  TITLE     Structure and chromosomal assignment of the human cyclin G gene
  JOURNAL   Genomics 38 (1), 92-95 (1996)
   PUBMED   8954786
REFERENCE   7  (bases 1 to 3418)
  AUTHORS   Okamoto,K., Kamibayashi,C., Serrano,M., Prives,C., Mumby,M.C. and
            Beach,D.
  TITLE     p53-dependent association between cyclin G and the B' subunit of
            protein phosphatase 2A
  JOURNAL   Mol Cell Biol 16 (11), 6593-6602 (1996)
   PUBMED   8887688
REFERENCE   8  (bases 1 to 3418)
  AUTHORS   Morita,N., Kiryu,S. and Kiyama,H.
  TITLE     p53-independent cyclin G expression in a group of mature neurons
            and its enhanced expression during nerve regeneration
  JOURNAL   J Neurosci 16 (19), 5961-5966 (1996)
   PUBMED   8815878
REFERENCE   9  (bases 1 to 3418)
  AUTHORS   Horne,M.C., Goolsby,G.L., Donaldson,K.L., Tran,D., Neubauer,M. and
            Wahl,A.F.
  TITLE     Cyclin G1 and cyclin G2 comprise a new family of cyclins with
            contrasting tissue-specific and cell cycle-regulated expression
  JOURNAL   J Biol Chem 271 (11), 6050-6061 (1996)
   PUBMED   8626390
REFERENCE   10 (bases 1 to 3418)
  AUTHORS   Okamoto,K. and Beach,D.
  TITLE     Cyclin G is a transcriptional target of the p53 tumor suppressor
            protein
  JOURNAL   EMBO J 13 (20), 4816-4822 (1994)
   PUBMED   7957050
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL646055.10.
            
            On Mar 4, 2023 this sequence version replaced NM_009831.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK153392.1, BC006609.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               AL646055.10        128042-128258       c
            218-478             AL646055.10        126849-127109       c
            479-732             AL646055.10        125145-125398       c
            733-811             AL646055.10        124481-124559       c
            812-910             AL646055.10        124302-124400       c
            911-3418            AL646055.10        121593-124100       c
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 24.42 cM"
     gene            1..3418
                     /gene="Ccng1"
                     /note="cyclin G1"
                     /db_xref="GeneID:12450"
                     /db_xref="MGI:MGI:102890"
     exon            1..217
                     /gene="Ccng1"
                     /inference="alignment:Splign:2.1.0"
     exon            218..478
                     /gene="Ccng1"
                     /inference="alignment:Splign:2.1.0"
     exon            479..732
                     /gene="Ccng1"
                     /inference="alignment:Splign:2.1.0"
     exon            733..811
                     /gene="Ccng1"
                     /inference="alignment:Splign:2.1.0"
     exon            812..910
                     /gene="Ccng1"
                     /inference="alignment:Splign:2.1.0"
     exon            911..3418
                     /gene="Ccng1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3398..3403
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccng1"
                     /note="hexamer: AATAAA"
     polyA_site      3418
                     /gene="Ccng1"
                     /note="major polyA site"
ORIGIN      
        1 gcagtccttc gctgcgcgct gaccccgagg aaggcagtac ttggtcaggg cgctgaggga
       61 ccctccaccg ggacgccggc ccctccccgg gcctctgctc acttgacccc cactccctag
      121 tccgtcccct tagtaggcct gtcggatcgg ggacgtgggg cgagctgaga gcaggcccgg
      181 ggtgggtggt caccgtggtg aagacgtggc tgtcaagatg atagaagtac tgacaactga
      241 ctctcagaaa ctgctacacc agctgaacac cctgttggaa caggagtcta gatgtcagcc
      301 aaaggtctgc ggcttgaaac taattgagtc ggcccatgat aatggcctca gaatgactgc
      361 aagattacgg gactttgaag taaaagatct acttagtcta actcagttct ttggctttga
      421 cacggagaca ttttccctag ctgtgaattt actggacaga ttcttgtcta aaatgaaggt
      481 acaggcgaag catcttgggt gtgttggact gagctgcttt tatttggctg tgaaagcgac
      541 tgaagaggaa aggaatgtcc cactggcgac tgatttgatc cgaataagtc agtataggtt
      601 cacggtttca gacctgatga gaatggagaa gattgtgttg gagaaagtgt gttggaaagt
      661 caaagctact actgcctttc aatttctgca gctctattat tcactcgttc acgacacctt
      721 gccatttgag aggagaaacg atctgaattt tgaaagacta gaagcccaac ttaaggcctg
      781 ccactgcagg atcatatttt ctaaggcaaa gccttctgtg ctggcgctat ctatccttgc
      841 gttggagatc caagcactga aatacgtaga gttaacagaa ggagtagaat gtattcagaa
      901 acattccaag ataagtggcc gagatttgac cttctggcaa gagcttgttt ccaagtgttt
      961 aactgaatat tcatcaaaca agtgctccaa acctaacggt cagaagttga aatggattgt
     1021 gtctggacgc actgcacggc aactgaagca cagttattat agaataactc acctcccaac
     1081 gattcctgag accatttgtt agttgataaa tctggttgtt attctctgta tacagaaaat
     1141 tttccagtat gatcattttc tgctacaact gaagaattga aatactatct tcaatataaa
     1201 gaatatggga tgaaaacata aaggaaaagt gaattgttga ctggtctaga tagagaatac
     1261 tggaaggcat tcactgtgta cagtgcgtag cagttttaag agaaaagaca tatcaaaccc
     1321 ctagatatac gctaatactt ttcatcaaaa gattagcgta gtagcaaaga gaatacttta
     1381 aactcgaatt ttaaaagtag ttactgaaat agcacttctt taaattacgt accaccccac
     1441 tgtagcttat ttaaagttgc ataagcccat gcagaacaac aagcaatgtg acccatatat
     1501 gaacaaattt taatctgccc atcgactatg aaaatgaagt acaaacctgg gtgatggact
     1561 tacaaagtaa tatagggcat gcccatgtta ggtttctgga aactgccaga gtgtcttaat
     1621 tctatagcta gtattttacc tctatagcat ttggactaat acaaagtaat tatatgcatg
     1681 aaaatataaa attggtctct gatacataca catttttgac atctaaattt cttaatcata
     1741 gcaaagattt atctttttat gattaaaaac aattttttcc ttaatgcatg gcagcacatg
     1801 cctttaatcc cagcactaga gaggcagaga caggtagatc tctgagttca aagccaggct
     1861 ggtctacaca gtgagttcca agacagctag agaccttgtc tcaaaaacac tcaaaacaac
     1921 caaacaccag gggtaaatgt tgctgggaag tcagggaaga tggtttagaa gggaagcctg
     1981 acaacctgac ttcattcttc aggacccaca tgatggaagg agagaacgaa gaactcccaa
     2041 gttctctcac atatgcacat acctcaccac cccccgcagg aaatacatga tcatgcgtct
     2101 gagatatcac cagttcacct ttagcagctc gcagtttgta ggcagatttc tgttaagttg
     2161 ggtctgtgtt gtttgcctat gtagcaggat tacagcagca gcaaaaacgg tccctcaagt
     2221 ctttctgcca ctctgacctg agtttcctac ggtacaggat ttactctgag aaacctcagc
     2281 accttgccac agtagccttg gcagaatggc ctcacggtta gggaaactcc tgattctaag
     2341 cttgggagag ctacgcttag atttgaattc acccaggaag cattcaaatc aaggctaaag
     2401 acataaatgt gaaataaaac tgtgaacctt cattctaaag ttcatctgac ttcccagatt
     2461 tgatcaatat attcttaggt ggtattaaaa atggtaaact gcttaattta aatctcaaaa
     2521 tttaaattat gaggtttaca taaaaaccaa catttcatga atgcactttt aaggtattaa
     2581 aaggggtact taagcggtaa atggtttctt ggcacccata accaagtaat agttaattta
     2641 caggtgggat ttttttttat tgctatgaga attacattta aaattgtggg tgttttatat
     2701 aaagcagata tcacaagttt tgaaaatttg ttacctttaa tatttcttct agagaatagg
     2761 tgtttgtatc cataataaaa gaaaaatttg tcagaactgc tgcttcaatc taatcccatt
     2821 tgagagaatt gtctttactg tcttaataac tggatgaatt atcactctga aaatgtattt
     2881 attgcactaa agttagttta ggcttgataa aacactccag acatttttac tacagactgt
     2941 ttctataaaa ctgccattgc ttctaatgga gaattttatt ttaaaagaaa taaaattgct
     3001 gagtttatct gcaaaacctt tctctaagtc ttatgggacg taaggagaca cctccataat
     3061 tataagagcc gttgtgctca gagtctccat gctggcttga atgtatgatc cacactgtta
     3121 aaacataggc agcagctcag ggccctggac agcctgagtc aacctagagt agctggaacc
     3181 attttgacat gtaatggata agaaaattat ccattgagaa gctgaacaat aaaccaaaga
     3241 acgggtgtat tttatcctta acctctgtaa accacgttac actgagaaca cttcagttct
     3301 tcctaaaggt tgataggctt cagtctgaaa acaatattga tttggagtgg acagaagtta
     3361 actaaccaac taccattatg ttttgaatac acctttcaat aaaatgattg aaatgcaa
//
