LOCUS       NM_007633               2022 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus cyclin E1 (Ccne1), mRNA.
ACCESSION   NM_007633
VERSION     NM_007633.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Nedomova,M., Haberecht-Muller,S., Moller,S., Venz,S.,
            Prochazkova,M., Prochazka,J., Sedlak,F., Chawengsaksophak,K.,
            Hammer,E., Kasparek,P., Adamek,M., Sedlacek,R., Konvalinka,J.,
            Kruger,E. and Grantz Saskova,K.
  TITLE     DDI2 protease controls embryonic development and inflammation via
            TCF11/NRF1
  JOURNAL   iScience 27 (10), 110893 (2024)
   PUBMED   39328932
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2022)
  AUTHORS   Yao,X., Wang,C., Yu,W., Sun,L., Lv,Z., Xie,X., Tian,S., Yan,L.,
            Li,L. and Liu,J.
  TITLE     BCAS2 regulates oocyte meiotic prophase I by participating in mRNA
            alternative splicing
  JOURNAL   FASEB J 38 (1), e23361 (2024)
   PUBMED   38085152
REFERENCE   3  (bases 1 to 2022)
  AUTHORS   Katano,W., Mori,S., Sasaki,S., Tajika,Y., Tomita,K., Takeuchi,J.K.
            and Koshiba-Takeuchi,K.
  TITLE     Sall1 and Sall4 cooperatively interact with Myocd and SRF to
            promote cardiomyocyte proliferation by regulating CDK and cyclin
            genes
  JOURNAL   Development 150 (24) (2023)
   PUBMED   38014633
REFERENCE   4  (bases 1 to 2022)
  AUTHORS   Otto,J., Verwaayen,A., Penners,C., Hundertmark,J., Lin,C.,
            Kallen,C., Paffen,D., Otto,T., Berger,H., Tacke,F., Weiskirchen,R.,
            Nevzorova,Y.A., Bartneck,M., Trautwein,C., Sonntag,R. and
            Liedtke,C.
  TITLE     Expression of Cyclin E1 in hepatic stellate cells is critical for
            the induction and progression of liver fibrosis and hepatocellular
            carcinoma in mice
  JOURNAL   Cell Death Dis 14 (8), 549 (2023)
   PUBMED   37620309
  REMARK    GeneRIF: Expression of Cyclin E1 in hepatic stellate cells is
            critical for the induction and progression of liver fibrosis and
            hepatocellular carcinoma in mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2022)
  AUTHORS   Cai,F., Song,B., Yang,Y., Liao,H., Li,R., Wang,Z., Cao,R., Chen,H.,
            Wang,J., Wu,Y., Zhang,Y. and Song,W.
  TITLE     USP25 contributes to defective neurogenesis and cognitive
            impairments
  JOURNAL   FASEB J 37 (6), e22971 (2023)
   PUBMED   37171286
REFERENCE   6  (bases 1 to 2022)
  AUTHORS   Fromm,L. and Overbeek,P.A.
  TITLE     Regulation of cyclin and cyclin-dependent kinase gene expression
            during lens differentiation requires the retinoblastoma protein
  JOURNAL   Oncogene 12 (1), 69-75 (1996)
   PUBMED   8552401
REFERENCE   7  (bases 1 to 2022)
  AUTHORS   Beijersbergen,R.L., Carlee,L., Kerkhoven,R.M. and Bernards,R.
  TITLE     Regulation of the retinoblastoma protein-related p107 by G1 cyclin
            complexes
  JOURNAL   Genes Dev 9 (11), 1340-1353 (1995)
   PUBMED   7797074
REFERENCE   8  (bases 1 to 2022)
  AUTHORS   Hirai,H., Roussel,M.F., Kato,J.Y., Ashmun,R.A. and Sherr,C.J.
  TITLE     Novel INK4 proteins, p19 and p18, are specific inhibitors of the
            cyclin D-dependent kinases CDK4 and CDK6
  JOURNAL   Mol Cell Biol 15 (5), 2672-2681 (1995)
   PUBMED   7739547
REFERENCE   9  (bases 1 to 2022)
  AUTHORS   Toyoshima,H. and Hunter,T.
  TITLE     p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is
            related to p21
  JOURNAL   Cell 78 (1), 67-74 (1994)
   PUBMED   8033213
REFERENCE   10 (bases 1 to 2022)
  AUTHORS   Damjanov,I., Shan,J., Wang,R.F., Damjanov,A. and DeLoia,J.A.
  TITLE     Molecular cloning and characterization of murine cyclin E
  JOURNAL   Biochem Biophys Res Commun 201 (2), 994-1000 (1994)
   PUBMED   8003041
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC106191.1.
            
            On Jul 7, 2006 this sequence version replaced NM_007633.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC106191.1, AK165658.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164140
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 25.35 cM"
     gene            1..2022
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /note="cyclin E1"
                     /db_xref="GeneID:12447"
                     /db_xref="MGI:MGI:88316"
     exon            1..169
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            170..212
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..1425
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /codon_start=1
                     /product="G1/S-specific cyclin-E1"
                     /protein_id="NP_031659.2"
                     /db_xref="CCDS:CCDS39914.1"
                     /db_xref="GeneID:12447"
                     /db_xref="MGI:MGI:88316"
                     /translation="MPRERDSTDHSNMKEEGGSDLSVRSRKRKANVAVFLQDPDEEIA
                     KIDKTVKSEDSSQPWDDNSACVDPCSFIPTPNKEEDNELEYPRTAFQPRKIRPPRASP
                     LPVLNWGNREEVWRIMLNKEKTYLRDEHFLQRHPLLQARMRAVLLDWLMEVCEVYKLH
                     RETFYLAQDFFDRYMASQHNIIKTLLQLIGISALFIASKLEEIYPPKLHQFAYVTDGA
                     CSGDEILTMELMMMKALKWRLSPLTIVSWLNVYVQVAYVNDTGEVLMPQYPQQVFVQI
                     AELLDLCVLDVGCLEFPYGVLAASALYHFSSLELMQKVSGYQWCDIEKCVKWMVPFAM
                     VIREMGSSKLKHFRGVPMEDSHNIQTHTNSLDLLDKAQAKKAILSEQNRISPPPSVVL
                     TPPPSSKKQSSEQETE"
     exon            213..300
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            301..369
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            370..518
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            519..654
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            655..801
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            802..897
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            898..1032
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1144
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            1145..1302
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1956
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1933..1938
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /note="hexamer: AATAAA"
     polyA_site      1956
                     /gene="Ccne1"
                     /gene_synonym="CycE1"
                     /note="major polyA site"
ORIGIN      
        1 cgaagccggg cgcaggagca gccggctcga cagccagcgc ggtgtagggg gcaggcgcgg
       61 atcccgccag cgccgcgcgc tcggccgccg cctcccgcct cctgcttccc gctcgccgtc
      121 ggcctcctgc ccgctcgagc gcgcctgcct gcggcggaca cagcttcggg tctgagttcc
      181 aagcccaagt cctgagccat gccaagggag agagactcga cggaccacag caacatgaaa
      241 gaagaaggtg gctccgacct ttcagtccgc tccagaaaaa ggaaggcaaa tgtggccgtg
      301 tttttgcaag acccagatga agaaattgcc aagattgaca agactgtgaa aagcgaggat
      361 agcagtcagc cctgggatga taattcagca tgcgtggacc cctgctcttt catccccacc
      421 cctaacaaag aagaggacaa tgagcttgaa taccccagga ctgcatttca gcctcggaaa
      481 atcagaccac ccagagcctc cccacttccc gtcttgaatt ggggcaatag agaagaggtt
      541 tggaggatca tgttaaacaa agaaaagact tacctgagag atgagcactt tctgcagcgt
      601 catcctctcc tgcaggcgag gatgagagca gttcttctgg attggctaat ggaggtgtgc
      661 gaagtctata agctccacag agagacgttc tacttggcac aggacttctt tgatcgttac
      721 atggcatcac aacataatat cataaaaaca cttttacagc ttattgggat ttcagcctta
      781 tttattgctt caaaacttga ggaaatctac cctccaaagt tgcaccagtt tgcttatgtt
      841 acagatggcg cttgctccgg ggatgaaatt cttaccatgg aattgatgat gatgaaggcc
      901 cttaagtggc gtctaagccc tctgaccatt gtgtcctggc tgaatgtcta tgtccaagtg
      961 gcctatgtca acgacacggg tgaggtgctg atgcctcagt acccacagca ggtcttcgtg
     1021 cagatcgcag agcttctaga cctgtgcgtc ctggatgttg gctgcttaga atttccttat
     1081 ggtgtcctcg ctgcttctgc tttgtatcat ttctcctcac tggagttgat gcagaaggtc
     1141 tcaggttatc agtggtgcga catagagaag tgtgtcaaat ggatggttcc gttcgccatg
     1201 gttatccggg agatgggaag ttccaagctc aagcacttcc ggggagtccc catggaagac
     1261 tcccacaaca tccagaccca caccaacagc ttggatttgc tggacaaagc ccaagcaaag
     1321 aaagccatat tgtcagaaca gaataggatt tctcctcctc cgagtgtggt cctgacaccc
     1381 ccacccagca gtaagaagca gagcagcgag caggagacag aatgaccaaa cctgccattg
     1441 cctccaaaga cagtggtgtg gaagcagctg cctggagctc cctgtgctgc cttggaggtc
     1501 aggagcccct gcagatgctg tgctctatgg agaggtgcat ctcttccgga gcagcagggg
     1561 tctgcaagat gccttggatg gaagtgcttt tattgaatgc taggtgtttt aactataggg
     1621 tcaagtacac cagccacctc cagaacacca ctgagtgctc cagaagctgc taaggagggt
     1681 gctacttgac ccactggact cttcacacag atgacacaag cttgaagtta aggaggccac
     1741 gccatggcgg ttgctggcct ctgctcgggt gttgtaggtt gctgttgata ggctgtgacc
     1801 agtggttgtg agcaagtgtg ggatgcagag cccacagcct ggcctaggct gcccttctcc
     1861 actgtcagcc aacagcatgt cctgccttca tgaactctta ttttgtaagt gctgctatgt
     1921 ctatcaattt ttaataaaga taatactatc tttgaaaaaa aaaaaaaaaa aaaaaaaaaa
     1981 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
