LOCUS       NM_001355127            1723 bp    mRNA    linear   ROD 24-DEC-2022
DEFINITION  Mus musculus cyclin D-type binding-protein 1 (Ccndbp1), transcript
            variant 2, mRNA.
ACCESSION   NM_001355127 XM_006498851
VERSION     NM_001355127.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1723)
  AUTHORS   Huang Y, Chen B, Ye M, Liang P, Zhangfang Y, Huang J, Liu M,
            Songyang Z and Ma W.
  TITLE     Ccndbp1 is a new positive regulator of skeletal myogenesis
  JOURNAL   J Cell Sci 129 (14), 2767-2777 (2016)
   PUBMED   27235421
  REMARK    GeneRIF: Ccndbp1 is a positive modulator of skeletal myogenic
            differentiation in vivo and in vitro.
REFERENCE   2  (bases 1 to 1723)
  AUTHORS   Motizuki M, Saitoh M and Miyazawa K.
  TITLE     Maid is a negative regulator of transforming growth
            factor-beta-induced cell migration
  JOURNAL   J Biochem 158 (5), 435-444 (2015)
   PUBMED   26002959
  REMARK    GeneRIF: Data suggest Maid/Ccndbp1 inhibits cell migration induced
            by TGFB1 (transforming growth factor-beta1) but not by BMP4 (bone
            morphogenetic protein-4); Maid does not alter cell proliferation,
            epithelial-mesenchymal transition, or TGFB3-induced apoptosis.
REFERENCE   3  (bases 1 to 1723)
  AUTHORS   Ishii R, Isogaya K, Seto A, Koinuma D, Watanabe Y, Arisaka F,
            Yaguchi S, Ikushima H, Dohmae N, Miyazono K, Miyazawa K, Ishitani R
            and Nureki O.
  TITLE     Structure of a dominant-negative helix-loop-helix transcriptional
            regulator suggests mechanisms of autoinhibition
  JOURNAL   EMBO J 31 (11), 2541-2552 (2012)
   PUBMED   22453338
REFERENCE   4  (bases 1 to 1723)
  AUTHORS   Sonnenberg-Riethmacher E, Wustefeld T, Miehe M, Trautwein C and
            Riethmacher D.
  TITLE     Maid (GCIP) is involved in cell cycle control of hepatocytes
  JOURNAL   Hepatology 45 (2), 404-411 (2007)
   PUBMED   17256742
  REMARK    GeneRIF: These results indicate that Maid is involved in G1/S-phase
            progression of hepatocytes, which in older animals is associated
            with the development of liver tumors.
REFERENCE   5  (bases 1 to 1723)
  AUTHORS   Ma W, Xia X, Stafford LJ, Yu C, Wang F, LeSage G and Liu M.
  TITLE     Expression of GCIP in transgenic mice decreases susceptibility to
            chemical hepatocarcinogenesis
  JOURNAL   Oncogene 25 (30), 4207-4216 (2006)
   PUBMED   16501603
REFERENCE   6  (bases 1 to 1723)
  AUTHORS   Chang MS, Chen CY, Yeh HI, Fan CC, Huang CJ and Yang YC.
  TITLE     Cloning, expression, and genomic organization of mouse mp29 gene
  JOURNAL   Biochem Biophys Res Commun 299 (2), 241-246 (2002)
   PUBMED   12437976
REFERENCE   7  (bases 1 to 1723)
  AUTHORS   Hwang SY, Oh B, Fuchtbauer A, Fuchtbauer EM, Johnson KR, Solter D
            and Knowles BB.
  TITLE     Maid: a maternally transcribed novel gene encoding a potential
            negative regulator of bHLH proteins in the mouse egg and zygote
  JOURNAL   Dev Dyn 209 (2), 217-226 (1997)
   PUBMED   9186056
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844548.7.
            
            [WARNING] On May 2, 2023 this sequence was replaced by
            NM_001355127.2.
            
            On Sep 8, 2017 this sequence version replaced XM_006498851.2.
            
            Transcript Variant: This variant (2) contains an alternate exon in
            the 3' end compared to variant 1, that causes a frameshift. The
            resulting isoform (2) has a longer and distinct C-terminus compared
            to isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1954853.1,
                                           SRR1660811.97924.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-202               AL844548.7         117396-117597
            203-262             AL844548.7         117706-117765
            263-342             AL844548.7         118031-118110
            343-424             AL844548.7         118815-118896
            425-521             AL844548.7         120422-120518
            522-595             AL844548.7         120671-120744
            596-672             AL844548.7         121341-121417
            673-950             AL844548.7         121687-121964
            951-1011            AL844548.7         122946-123006
            1012-1162           AL844548.7         123501-123651
            1163-1209           AL844548.7         125119-125165
            1210-1723           AL844548.7         125387-125900
FEATURES             Location/Qualifiers
     source          1..1723
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..1723
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /note="cyclin D-type binding-protein 1"
                     /db_xref="GeneID:17151"
                     /db_xref="MGI:MGI:109595"
     exon            1..202
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            203..262
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            263..342
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            343..424
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            425..521
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            522..595
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            596..672
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            673..950
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1011
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1162
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1209
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
     exon            1210..1723
                     /gene="Ccndbp1"
                     /gene_synonym="DIP1; GCIP; Maid; SECC-8; SSEC-8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgtgtgtt gccggaaacg agatgagttt ttcagcaccg gaagtactgc ggcggggcca
       61 aatggcttaa gcgtcttagc tggttcccag agagagcctg cgatggcgag ctcgacagcc
      121 gcagtcccct tccttgctcc gcctctggag cagctccggc acttagcaga ggagctacgg
      181 tcacttctgc ctcgagtacg ggtcggcgaa gcccaggaga cagcggagga atttaatcga
      241 gaaatgtttt ggagaagact caatgaggca gcagtgaaag tgaacgggga agccactgtt
      301 ctgacaacgc acttctctaa acttccatgg ccatctccac aggaaaccca gaggatctgt
      361 gagcaagtcc gtattgccat cgaggaaata attatagtgt attattcact tcctaaggac
      421 cagggaatca ccctgagaaa gctggtacgg aatgctgccc tggacatcgt ggacggcatg
      481 gctcagctcc tggaagtgct tcttactgct ccatctcaga gcactgagaa tggtgacctg
      541 atttcctgca atagtgtctc agtcgcatgt caacaggtgc ctgagatccc aaaagataac
      601 aaagccgcag cccttttgat gctgaccaag agtgtggatt ttgtgaaaga tgcacatgaa
      661 gaaatggagc aggctgtaga agaatgtgac ccgtacagcg gcctcttgaa tgattctgaa
      721 gacaactccg acagccacag tgatgaggat ggtgtgttag ggcttcccag caatcgggac
      781 tcatactggt cagaggaaga tcaagaactc ataatcccgt gcctggcgct ggtgagagca
      841 tcccgagctt cactcaagaa aatccggatc ttggtggctg agaatggaaa gaaggatgag
      901 gtggcccagc tggatgacat tgtggacatt tctgatgaga tcagccccag tgtggatgac
      961 ttggttctga gcatataccc acctgtgtgc cacctcactg tgcggatcag tgtgaatgtg
     1021 tggacactca gaggctctgt cactcttcct gattaccctg agacagttca ctcactgaac
     1081 ctggagctgg tctggcagca agcaagccca gcgatcgcct tgcctctgtg cccacagcgc
     1141 tggagtaaca gatacacgca tgtctgcgaa attggtgtct gttttaataa aggctcttga
     1201 aattacaaaa gcaagtcacg tgagccccca cccaggagat agctggattc ctttactcat
     1261 taatgccgtt gaccattgca tgaacagaat taaggcgctc actcagcgtg cagctgaact
     1321 gtgagcctcc aatccctact cttctttctc ccctctctct cacacccacg atccagtgtc
     1381 tgctttacct atttattttt taagtttttt taacgtctgc ttttagaagt ggagctttga
     1441 cagggtgttt gctcgataga aaggcagcct ctgtccttaa gaagagattg ttaccaagac
     1501 tccaggctag gagagattgc agttatccac caatcataca gtgtgctatg cttctgtgct
     1561 ggacacaaat ttctataaac ttgtgctctg agctgttttt tggaaatctt taaggaagtt
     1621 gacttgttct ctagtttact acagtaaagc atattgtttt attaagattt taatgatctc
     1681 aataaattgc taacctgctg tgattaaatg tgtcatttaa tgt
//
