LOCUS       NM_009139               1436 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus C-C motif chemokine ligand 6 (Ccl6), mRNA.
ACCESSION   NM_009139
VERSION     NM_009139.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1436)
  AUTHORS   Lee,H., Lee,G., Cho,Y.H., Song,Y. and Ko,G.
  TITLE     Chemokine CCL6 Plays Key Role in the Inhibitory Effect of Vitamin A
            on Norovirus Infection
  JOURNAL   J Microbiol 61 (5), 579-587 (2023)
   PUBMED   37233907
  REMARK    GeneRIF: Chemokine CCL6 Plays Key Role in the Inhibitory Effect of
            Vitamin A on Norovirus Infection.
REFERENCE   2  (bases 1 to 1436)
  AUTHORS   Feng,X., Ji,Y., Zhang,C., Jin,T., Li,J. and Guo,J.
  TITLE     CCL6 promotes M2 polarization and inhibits macrophage autophagy by
            activating PI3-kinase/Akt signalling pathway during skin wound
            healing
  JOURNAL   Exp Dermatol 32 (4), 403-412 (2023)
   PUBMED   36457234
  REMARK    GeneRIF: CCL6 promotes M2 polarization and inhibits macrophage
            autophagy by activating PI3-kinase/Akt signalling pathway during
            skin wound healing.
REFERENCE   3  (bases 1 to 1436)
  AUTHORS   Gao,H., Cao,M., Deng,K., Yang,Y., Song,J., Ni,M., Xie,C., Fan,W.,
            Ou,C., Huang,D., Lin,L., Liu,L., Li,Y., Sun,H., Cheng,X., Wu,J.,
            Xia,C., Deng,X., Mou,L. and Chen,P.
  TITLE     The Lineage Differentiation and Dynamic Heterogeneity of Thymic
            Epithelial Cells During Thymus Organogenesis
  JOURNAL   Front Immunol 13, 805451 (2022)
   PUBMED   35273595
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1436)
  AUTHORS   Kurz,J., Weiss,A.C., Thiesler,H., Qasrawi,F., Deuper,L., Kaur,J.,
            Rudat,C., Ludtke,T.H., Wojahn,I., Hildebrandt,H., Trowe,M.O. and
            Kispert,A.
  TITLE     Notch signaling is a novel regulator of visceral smooth muscle cell
            differentiation in the murine ureter
  JOURNAL   Development 149 (4) (2022)
   PUBMED   35103284
REFERENCE   5  (bases 1 to 1436)
  AUTHORS   Du,X., Li,F., Zhang,C., Li,N., Huang,H., Shao,Z., Zhang,M.,
            Zhan,X., He,Y., Ju,Z., Li,W., Chen,Z., Ying,S. and Shen,H.
  TITLE     Eosinophil-derived chemokine (hCCL15/23, mCCL6) interacts with CCR1
            to promote eosinophilic airway inflammation
  JOURNAL   Signal Transduct Target Ther 6 (1), 91 (2021)
   PUBMED   33640900
  REMARK    GeneRIF: Eosinophil-derived chemokine (hCCL15/23, mCCL6) interacts
            with CCR1 to promote eosinophilic airway inflammation.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1436)
  AUTHORS   Krulova,M., Havelkova,H., Kosarova,M., Holan,V., Hart,A.A.,
            Demant,P. and Lipoldova,M.
  TITLE     IL-2-induced proliferative response is controlled by loci Cinda1
            and Cinda2 on mouse chromosomes 11 and 12: a distinct control of
            the response induced by different IL-2 concentrations
  JOURNAL   Genomics 42 (1), 11-15 (1997)
   PUBMED   9177770
REFERENCE   7  (bases 1 to 1436)
  AUTHORS   Ohshima,T., Kozak,C.A., Nagle,J.W., Pant,H.C., Brady,R.O. and
            Kulkarni,A.B.
  TITLE     Molecular cloning and chromosomal mapping of the mouse gene
            encoding cyclin-dependent kinase 5 regulatory subunit p35
  JOURNAL   Genomics 35 (2), 372-375 (1996)
   PUBMED   8661152
REFERENCE   8  (bases 1 to 1436)
  AUTHORS   Kozak,C.A., Danciger,M., Bowes,C., Adamson,M.C., Palczewski,K.,
            Polans,A.S. and Farber,D.B.
  TITLE     Localization of three genes expressed in retina on mouse chromosome
            11
  JOURNAL   Mamm Genome 6 (2), 142-144 (1995)
   PUBMED   7767000
REFERENCE   9  (bases 1 to 1436)
  AUTHORS   Berger,M.S., Kozak,C.A., Gabriel,A. and Prystowsky,M.B.
  TITLE     The gene for C10, a member of the beta-chemokine family, is located
            on mouse chromosome 11 and contains a novel second exon not found
            in other chemokines
  JOURNAL   DNA Cell Biol 12 (9), 839-847 (1993)
   PUBMED   8216854
REFERENCE   10 (bases 1 to 1436)
  AUTHORS   Orlofsky,A., Berger,M.S. and Prystowsky,M.B.
  TITLE     Novel expression pattern of a new member of the MIP-1 family of
            cytokine-like genes
  JOURNAL   Cell Regul 2 (5), 403-412 (1991)
   PUBMED   1832565
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY172106.1, AK002697.1, M58004.1 and AV014853.1.
            
            On Mar 2, 2007 this sequence version replaced NM_009139.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M58004.1, AK154553.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-371               BY172106.1         1-371
            372-851             AK002697.1         275-754
            852-1430            M58004.1           755-1333
            1431-1436           AV014853.1         165-170
FEATURES             Location/Qualifiers
     source          1..1436
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 50.85 cM"
     gene            1..1436
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /note="C-C motif chemokine ligand 6"
                     /db_xref="GeneID:20305"
                     /db_xref="MGI:MGI:98263"
     exon            1..222
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..497
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /note="C-C motif chemokine 6; CC chemokine C10;
                     small-inducible cytokine A6; chemokine (C-C motif) ligand
                     6"
                     /codon_start=1
                     /product="C-C motif chemokine 6 precursor"
                     /protein_id="NP_033165.1"
                     /db_xref="CCDS:CCDS25171.1"
                     /db_xref="GeneID:20305"
                     /db_xref="MGI:MGI:98263"
                     /translation="MRNSKTAISFFILVAVLGSQAGLIQEMEKEDRRYNPPIIHQGFQ
                     DTSSDCCFSYATQIPCKRFIYYFPTSGGCIKPGIIFISRRGTQVCADPSDRRVQRCLS
                     TLKQGPRSGNKVIA"
     exon            223..270
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /inference="alignment:Splign:2.1.0"
     exon            271..382
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /inference="alignment:Splign:2.1.0"
     exon            383..1436
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      908..913
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /note="hexamer: AATAAA"
     polyA_site      933
                     /gene="Ccl6"
                     /gene_synonym="c10; MRP-1; Scya6"
                     /note="major polyA site"
ORIGIN      
        1 ttgtgtatta tgtagccagg gacagcattc tgaactctac cctggcactt cctgaacctc
       61 ctagcttata aataccaggg caggccagag aatcagggag gagtgagcaa aaattctcag
      121 accagctggg cctgtcctcc aggaggatga gaaactccaa gactgccatt tcattcttta
      181 tccttgtggc tgtccttggg tcccaggctg gcctcataca agaaatggaa aaagaagatc
      241 gtcgctataa ccctccaata attcatcaag gctttcaaga cacttcttca gactgctgct
      301 tctcttatgc cacacagatc ccatgtaaaa gatttatata ttatttcccc accagtggtg
      361 ggtgcatcaa gccgggcatc atctttatca gcaggagggg aacccaggtc tgtgccgacc
      421 ccagcgatcg gagagttcag aggtgcctaa gcaccctgaa gcaaggccca agatctggga
      481 acaaggtcat tgcttgagaa ggagggcagg cattgtcacc cactttcttc tgtcttcccc
      541 agtgaccgcc tgcctaggag accttgtttt tatagatatt taaagcattt atccttctgt
      601 tcaggtttag agcagtcaac agtattcatg tggactccgc ctgacacggt tagagccatc
      661 tggagttgta aacatcaaga ttgtctttga gtaattgttg ggtttttttt cggtttctca
      721 gcagattata aatggataca ttattagggt agtctttggg gctttggaat gtgtctggtt
      781 ctgatacaag cttaagccgg gtaatatcta gctgagatga aatcaatttt gccctaggcc
      841 atacatatgt ccagctttgt gggttcccag ttgttcgccc tgccacaata gagcaatgag
      901 tgcccccaat aaagtccact ccatgtagcc acaggactgt ctctttcttc agattcatag
      961 aactacgggg ccagtctgaa actgggctct tggggtgaaa ttatctcact cactcacctt
     1021 gagtacagga gggagatggg accatataac tttgaatatt ctaaaccaaa agacatcatg
     1081 gtataatttt taaaaattaa gaacacggtt tattcctctg agcttggtgc aaaacagagg
     1141 aatacctttt ccagcagggc gtcttcttct ctgcctgact tttatctgcg gaacctgacc
     1201 ttcacaccct ctacctgagg aagttcaggt agttgttggc aaatctacaa gtaagaacct
     1261 gcacaccaag tatctgggat tcctggaatg cctctccatg caaatgaggc attcccagta
     1321 ctttaaactt catctagtaa tttacattta ccctgaaaac tccttcctat actccaaggt
     1381 tcatgtatag ccctggttta ccccaataaa gtgtatgcac acaagctgtt tcactg
//
