LOCUS       NM_001384257             586 bp    mRNA    linear   ROD 26-SEP-2023
DEFINITION  Mus musculus C-C motif chemokine ligand 27A like (Ccl27al),
            transcript variant 5, mRNA.
ACCESSION   NM_001384257 XM_030252990
VERSION     NM_001384257.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Davila ML, Xu M, Huang C, Gaddes ER, Winter L, Cantorna MT, Wang Y
            and Xiong N.
  TITLE     CCL27 is a crucial regulator of immune homeostasis of the skin and
            mucosal tissues
  JOURNAL   iScience 25 (6), 104426 (2022)
   PUBMED   35663027
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  AUTHORS   Church DM, Schneider VA, Graves T, Auger K, Cunningham F, Bouk N,
            Chen HC, Agarwala R, McLaren WM, Ritchie GR, Albracht D, Kremitzki
            M, Rock S, Kotkiewicz H, Kremitzki C, Wollam A, Trani L, Fulton L,
            Fulton R, Matthews L, Whitehead S, Chow W, Torrance J, Dunn M,
            Harden G, Threadgold G, Wood J, Collins J, Heath P, Griffiths G,
            Pelan S, Grafham D, Eichler EE, Weinstock G, Mardis ER, Wilson RK,
            Howe K, Flicek P and Hubbard T.
  TITLE     Modernizing reference genome assemblies
  JOURNAL   PLoS Biol 9 (7), e1001091 (2011)
   PUBMED   21750661
REFERENCE   3  (bases 1 to 586)
  AUTHORS   Church DM, Goodstadt L, Hillier LW, Zody MC, Goldstein S, She X,
            Bult CJ, Agarwala R, Cherry JL, DiCuccio M, Hlavina W, Kapustin Y,
            Meric P, Maglott D, Birtle Z, Marques AC, Graves T, Zhou S, Teague
            B, Potamousis K, Churas C, Place M, Herschleb J, Runnheim R,
            Forrest D, Amos-Landgraf J, Schwartz DC, Cheng Z, Lindblad-Toh K,
            Eichler EE and Ponting CP.
  CONSRTM   Mouse Genome Sequencing Consortium
  TITLE     Lineage-specific biology revealed by a finished genome assembly of
            the mouse
  JOURNAL   PLoS Biol 7 (5), e1000112 (2009)
   PUBMED   19468303
REFERENCE   4  (bases 1 to 586)
  AUTHORS   Gortz A, Nibbs RJ, McLean P, Jarmin D, Lambie W, Baird JW and
            Graham GJ.
  TITLE     The chemokine ESkine/CCL27 displays novel modes of intracrine and
            paracrine function
  JOURNAL   J Immunol 169 (3), 1387-1394 (2002)
   PUBMED   12133963
REFERENCE   5  (bases 1 to 586)
  CONSRTM   IUIS/WHO Subcommittee on Chemokine Nomenclature
  TITLE     Chemokine/chemokine receptor nomenclature
  JOURNAL   J Immunol Methods 262 (1-2), 1-3 (2002)
   PUBMED   12080938
REFERENCE   6  (bases 1 to 586)
  AUTHORS   Nakano H and Gunn MD.
  TITLE     Gene duplications at the chemokine locus on mouse chromosome 4:
            multiple strain-specific haplotypes and the deletion of secondary
            lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the
            plt mutation
  JOURNAL   J Immunol 166 (1), 361-369 (2001)
   PUBMED   11123313
REFERENCE   7  (bases 1 to 586)
  AUTHORS   Morales J, Homey B, Vicari AP, Hudak S, Oldham E, Hedrick J, Orozco
            R, Copeland NG, Jenkins NA, McEvoy LM and Zlotnik A.
  TITLE     CTACK, a skin-associated chemokine that preferentially attracts
            skin-homing memory T cells
  JOURNAL   Proc Natl Acad Sci U S A 96 (25), 14470-14475 (1999)
   PUBMED   10588729
REFERENCE   8  (bases 1 to 586)
  AUTHORS   Baird JW, Nibbs RJ, Komai-Koma M, Connolly JA, Ottersbach K,
            Clark-Lewis I, Liew FY and Graham GJ.
  TITLE     ESkine, a novel beta-chemokine, is differentially spliced to
            produce secretable and nuclear targeted isoforms
  JOURNAL   J Biol Chem 274 (47), 33496-33503 (1999)
   PUBMED   10559234
REFERENCE   9  (bases 1 to 586)
  AUTHORS   Ishikawa-Mochizuki I, Kitaura M, Baba M, Nakayama T, Izawa D, Imai
            T, Yamada H, Hieshima K, Suzuki R, Nomiyama H and Yoshie O.
  TITLE     Molecular cloning of a novel CC chemokine, interleukin-11 receptor
            alpha-locus chemokine (ILC), which is located on chromosome 9p13
            and a potential homologue of a CC chemokine encoded by molluscum
            contagiosum virus
  JOURNAL   FEBS Lett 460 (3), 544-548 (1999)
   PUBMED   10556532
REFERENCE   10 (bases 1 to 586)
  AUTHORS   Hromas R, Broxmeyer HE, Kim C, Christopherson K 2nd and Hou YH.
  TITLE     Isolation of ALP, a novel divergent murine CC chemokine with a
            unique carboxy terminal extension
  JOURNAL   Biochem Biophys Res Commun 258 (3), 737-740 (1999)
   PUBMED   10329455
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL824709.35.
            
            On Jun 12, 2020 this sequence version replaced XM_030252990.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1551028.1,
                                           ERR3363658.4181232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                AL824709.35        124812-124854
            44-110              AL824709.35        125247-125313
            111-170             AL824709.35        125525-125584
            171-268             AL824709.35        128454-128551
            269-401             AL824709.35        129748-129880
            402-586             AL824709.35        130070-130254
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 22.29 cM"
     gene            1..586
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /note="C-C motif chemokine ligand 27A like"
                     /db_xref="GeneID:100039863"
                     /db_xref="MGI:MGI:3713752"
     exon            1..43
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..558
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /note="isoform 5 is encoded by transcript variant 5"
                     /codon_start=1
                     /product="chemokine (C-C motif) ligand 27b isoform 5"
                     /protein_id="NP_001371186.1"
                     /db_xref="GeneID:100039863"
                     /db_xref="MGI:MGI:3713752"
                     /translation="MQAPHIECEGTVRSPDRSRLRRYEVALEAEEDIYWGCFYFFPWL
                     RMWRRERSPMSPTSQRLSLEAPSLPLRSWHPWNKTKQKQEALPLPSSTSCCTQLYRQP
                     LPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGT
                     VPSLNLVLQKKMYSHPQQQN"
     exon            44..110
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /inference="alignment:Splign:2.1.0"
     exon            111..170
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /inference="alignment:Splign:2.1.0"
     exon            171..268
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /inference="alignment:Splign:2.1.0"
     exon            269..401
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /inference="alignment:Splign:2.1.0"
     exon            402..586
                     /gene="Ccl27al"
                     /gene_synonym="100039939; Gm13306; Gm2506"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccccttctgg gtgatatgca agccccacac atagaatgcg aaggaaccgt tcggagcccg
       61 gacaggtcgc gattgaggag atacgaggtg gcgctggaag cggaggagga tatctactgg
      121 ggctgcttct acttttttcc ttggctgcga atgtggcgca gggagcggag tccgatgtct
      181 ccaacaagcc agagactaag tctggaagcc cccagcctcc cactgagaag ctggcatccg
      241 tggaacaaga ctaagcagaa gcaagaagcc ttgcctctgc cctccagcac tagctgctgt
      301 actcagctct atagacagcc actcccaagc aggctgctga ggaggattgt ccacatggaa
      361 ctgcaggagg ctgatgggga ctgtcacctc caggctgtcg tgcttcacct ggctcggcgc
      421 agtgtctgtg ttcatcccca gaaccgcagc ctggctcggt ggttagaacg ccaagggaaa
      481 aggctccaag gaactgtacc cagtttaaat ctggtactac aaaagaaaat gtactcacac
      541 ccccaacagc aaaactaata aagcaacatt agacgacaat ctccaa
//
