LOCUS       NM_001025156            7272 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus coiled-coil domain containing 93 (Ccdc93), transcript
            variant 1, mRNA.
ACCESSION   NM_001025156
VERSION     NM_001025156.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7272)
  AUTHORS   Kumar,N., Yang,M.L., Sun,P., Hunker,K.L., Li,J., Jia,J., Fan,F.,
            Wang,J., Ning,X., Gao,W., Xu,M., Zhang,J., Chang,L., Chen,Y.E.,
            Huo,Y., Zhang,Y. and Ganesh,S.K.
  TITLE     Genetic variation in CCDC93 is associated with elevated central
            systolic blood pressure, impaired arterial relaxation, and
            mitochondrial dysfunction
  JOURNAL   PLoS Genet 20 (9), e1011151 (2024)
   PUBMED   39250516
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7272)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY136404.1, BC054083.1, AC111011.6 and CO042243.1.
            
            On Nov 15, 2007 this sequence version replaced NM_001025156.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK142302.1, AK159415.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                BY136404.1         1-97
            98-2389             BC054083.1         1-2292
            2390-6618           AC111011.6         67522-71750
            6619-7272           CO042243.1         1-654               c
FEATURES             Location/Qualifiers
     source          1..7272
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 52.97 cM"
     gene            1..7272
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /note="coiled-coil domain containing 93"
                     /db_xref="GeneID:70829"
                     /db_xref="MGI:MGI:1918079"
     exon            1..191
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..2039
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     coiled-coil domain-containing protein 93"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 93 isoform
                     a"
                     /protein_id="NP_001020327.1"
                     /db_xref="CCDS:CCDS15237.1"
                     /db_xref="GeneID:70829"
                     /db_xref="MGI:MGI:1918079"
                     /translation="MGLPKGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARI
                     KGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQ
                     LEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSISQFQKTYSLPEDDDFIK
                     RKDKAVKTVVGLSDAYKPRRKYRRQRGAEELPDEESRVHSTLLEYGRRYGFSRQSKTE
                     KAEDKKTALAAGLSAAEKVDAHEEDELQAAEEQRIQSLMTKMTAMANEESRLTASSVG
                     QIVGLCSEEIKQIVSEYAGKQSELSAEESPEKLGTSQLHQRKVISLNKQILQKSKHLE
                     ELQANHTSLKAKYSDRKKTLTELKDHGEKLDKEQAALEKLEAKADPSMLQNLRALVAM
                     NESLKSQEQEFKAHCREEMARLQQEIETLKAERAPGEKIISGGEPQGALTSTMTHNED
                     LDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISA
                     VHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVE
                     GIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKI
                     KAKAS"
     exon            192..305
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            306..400
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            401..512
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            513..611
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            612..668
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            669..769
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            770..806
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            807..899
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            900..950
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            951..1037
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1154
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1217
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1291
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1373
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1374..1439
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1440..1493
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1556
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1665
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1748
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1786
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1871
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1872..1985
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..7256
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2366..2371
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2389
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
     regulatory      7234..7239
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /note="hexamer: AATAAA"
     polyA_site      7256
                     /gene="Ccdc93"
                     /gene_synonym="4633402D15Rik; 9230102M16Rik"
                     /note="major polyA site"
ORIGIN      
        1 tagtgcgcat gctccgcggg gccacggttc tccgacctgc tgtggtagtg tcagctcctg
       61 tgaaggaagt ttccgctttg caccccaccc ggatcacagt tcggttgtag ggcccgctct
      121 ctccggctcc acatcagcgc atctggatca tggggttacc caaggggcca gagggccagg
      181 gactcccgga ggtggagacg agagaagacg aagaacagaa tgtcaagctg actgaaatcc
      241 tggagctctt ggtcgcagct ggctatttca gagcaagaat taaaggcttg tctcctttcg
      301 acaaggtagt aggaggaatg acgtggtgta tcaccacatg cagctttgat gtggacgtgg
      361 atttgctctt tcaagaaaac tctacaatcg gtcagaaaat tgctctatcg gaaaagattg
      421 tctccgtcct cccaaggatg aagtgtcccc accagctgga gccccaccag atccagggca
      481 tggattttat ccacatattc cctgtcgtgc agtggctggt gaaacgagct atcgaaacaa
      541 aggaagagat gggagactac atccgctcct actccatctc tcagttccag aagacctaca
      601 gcctcccgga ggatgatgac ttcataaaga gaaaagacaa ggccgtcaag acggtcgttg
      661 gcctctcgga tgcttacaag ccccggcgaa agtaccgacg gcagcgggga gcagaggagc
      721 tgccagacga agagtcccga gtccactcca cacttctgga atatggcagg agatacggat
      781 ttagtcgcca gagcaaaaca gagaaggctg aggacaagaa aacagcactt gctgcagggc
      841 tgtcagctgc agagaaagtg gatgctcacg aggaagatga gcttcaggca gccgaagagc
      901 agcgtattca gtcactgatg accaagatga ccgccatggc aaacgaggag agccgtctca
      961 ccgcaagctc cgtgggccag atcgtgggtc tctgctctga ggagatcaag cagattgtgt
     1021 ctgagtacgc agggaagcag tctgagctgt ccgctgaaga aagtccagag aagttaggaa
     1081 cctcccagct gcatcagcgg aaagtcattt ccttgaataa gcagattctg cagaagagca
     1141 aacatctgga agagctgcaa gcgaatcata ccagcctcaa agccaagtac agcgacagga
     1201 agaagacact gacagagttg aaggatcatg gtgagaaact agacaaagag caggcagccc
     1261 tggagaaatt agaagccaaa gccgacccaa gcatgctgca gaacctgaga gcacttgtag
     1321 ccatgaatga aagtctgaaa agccaggagc aggagtttaa ggcacactgc cgggaggaga
     1381 tggctcggct acaacaggaa attgagaccc tgaaagctga gagagcacca ggtgagaaga
     1441 tcatctctgg tggagagccg cagggtgccc tgacctccac catgactcac aatgaggacc
     1501 tggacagacg gtacaacatg gaaaaagaga agctgtacaa gatccggtta ctacaggcac
     1561 gaagaaatcg agaaatagca attttgcatc gcaagattga cgaagtgccc agtcgagcag
     1621 agctgataca gtatcagaag cgatttattg aactctaccg tcagatttcc gcagtgcaca
     1681 aggaaaccaa gcagttcttc actttgtaca ataccctgga tgacaaaaag gtttacctgg
     1741 agaaggagat tagcctgctg aactctattc acgagaactt ctcacaagcc atggcctccc
     1801 ctgctgcccg ggaccagttt ttaaggcaga tggaacagat cgtcgaaggc attaaacaaa
     1861 gcaggatgaa gatggaaaag aagaagcagg agaacaagat gaggagggac cagttgaacg
     1921 atcagtactt ggagctcctg gaaaagcaga ggctctactt caagactgtg aaagagttca
     1981 aagaggaggg ccgaaagaat gagctattac tatctaagat caaagccaag gcctcctgaa
     2041 aactccatct ccgtttctgg atgtccctga tattttttta atgacgtgta tagactacag
     2101 gatcttgaca tggttctgcc ggtgatggca gagagaccca ggaaaattca tttcagttct
     2161 ctagacggat gttgtctttc tcctacttgt ttcatttcgt ctctcctggc tgcggctgat
     2221 ggactcagag ccctacaaag aaccgtgggc agtgtggatg acactcagag ccccataggc
     2281 agtgcccact cactctgacc actcaacttc catttcttca gtgacactgc atttatgaag
     2341 gtaccggatg tgtgcgggcc ctgagaataa agagcattat gttcagcaag tattgagcaa
     2401 ctgctaagaa ataagccctg aggtaaatgt agccgaacac ggtccctgcc cttatggtat
     2461 ctggcagagg cccagagaac aaccctcttg gtcccctccc ccaaagcttg tcccctgaaa
     2521 tgtttcaaat ggctgctgga tgagcagcca gcccgttcac ctaccattgt gccttttgtt
     2581 ctggcttgtc acagtacgta aggactctag gctgggttgg ggtgcagagc aattagccca
     2641 gaggtgtaaa gacagaagca ggcgaggttc aggttgacta gagtccaccc atttgtgttg
     2701 tgaagactga taccaggtgc ccatgatggc ctttggaaac aggaacccct ggtctggagc
     2761 cgtgcttctc aggcatctgc tctggtgtgg ctgtaggtgt gtcctgtcct ctggctacat
     2821 gtggtcaagc ctagctgtga gggtgctgga agcatatccc atgttcttgc actgtcaggg
     2881 tttcagtaaa gataggatgt atagactgtt gagtactatc cggtcagaca aggggaaaga
     2941 cttcgggtgc tgtgcatgga ggaaaagatg gtagtaacag gggcaggaag actccacgga
     3001 gtgaacagca cttgggccag agccaaaagg agtaggatgt tagctgagat gggaaggagg
     3061 gcctctaata acccctaaat ggttggcttt agcctctgga catgagcaga ccaaagcaat
     3121 cacagagcac tcccagaccc ccaggtatcg gaaacctagc aactgggtca tgctaggtaa
     3181 accccagtgt gagatttgtg ctcccttctg tataaactta gcatacacat gaacagcagg
     3241 ttgggaccat taagcagaag caggtggggg cattgggcag tcacagaaga agtgcttctc
     3301 aactttagtt tcctaatgta tgattgagag gcatgaggca tgcatactga taggaaagaa
     3361 ggggtgctgg gctcagtggg tagggtgctt gtctaggttc catccctagc atcacataaa
     3421 tagacatggt agcacacact tgtgatagag gcaggaggat caggactttg agtgtatcct
     3481 aggctagaat ttcttttggt gtggttgtag gcatgatcaa ctacaggctg cctgtagcca
     3541 aggatagctg tgaaggtggc ccaacatgaa attgtaaagt aatttagaac acagattatt
     3601 ttccatctct tctcttaaaa ctccattaca ctatgtactc cataaacttt gtaggtggcg
     3661 gggtcatgtt gtaaaagcat aacggtgatc actcctgata gagagagatt gggttggtaa
     3721 ctcttggtag agagaggttg gtggctactt tgtcccattc cttaatccgc aaggcttaat
     3781 agagatgatg agaggttcct gttcttctgt accaggtaca accgccctcc tgaggagcag
     3841 gcaagagatc taaacagaat aaggtggttg acctatgcct ctctgagtcc agtgctctcg
     3901 tcttgcctgg cagatttgta ttacaggctg caagtccata gctgggtaag gctgttgctg
     3961 acactgttac cccagcgtct gtgcagcaac atctgacaca gggaaagcta agccatcaga
     4021 ggagaggctt cgagctcaga tctaccttga tttctctctc ctacattcaa agtacgtgtt
     4081 acctaaagca gtaatgtctt actatctggt tctggtaagc aacaatgagc agcggccgac
     4141 ctgtattgtt tagagctttg tgggtagact gtgttattct ttcaattaaa cctgaggacc
     4201 ctacatttgt atcagacatc ctaaatcaga tagacaacac tttcgtgagt aattccagca
     4261 tgaagtgggc tgctcagtct gacttattgt tggctgagga gattccctga gatccctggt
     4321 cagttcagaa tccacctgga ggctggtgga aggggagggc ctctcagggt agtgtcttct
     4381 gtacccagac atagctgtac ccagacatag tatagcattg tatttggagc ctactggctt
     4441 ttaccagaat tgtaagatgg tggggaaaca tctgtaggtg agtctttttt ttttttggtg
     4501 tgtttgtttg tttgtttgtt tgtttgtttg tttcagtgtg tactttaaga gaagccagat
     4561 tcagagcaga gagcttgttc acggggctgg ctcccagtgc catgcattct taggaccagc
     4621 ctctaggtca ggagctacct cccctcccat atgcttttca tgaagttcct gaggatgctc
     4681 tggttgagac caagctcaga gcagctgtga gcaggctgag actgaggtga tggtggaagg
     4741 cctgggagga tgtagggacg ttctctactt ctccgtgttc agtggttagt cggccagcac
     4801 cacaggggca gtggcgagta ccatagaata tctgtcaacc tgcatccaga ggtactgtaa
     4861 tgaagcagag tccacgctgg gcataagctc ctgttagtct gatcttctgg atcagggtct
     4921 ggtttgtagc acttgattca agaacagtgg agacgcaggc ttgtggtgga accaagccag
     4981 cattggtctc caggaaaggc tttccttctc cagactgttt ctgggggacc cctgaggacc
     5041 ttgaacaaag cacggggcag gccttccaac agctctctta ctacctccca aggtgccagt
     5101 cctatccttg gcactttggc agactcctgt cttttctatc ttgaatattg tagtcactac
     5161 ctgaaggggt atctgagaga cacccagcct gacctgcaac ccctatagtg catcccttct
     5221 ccatggttct gtcttgcctg ctcccaaggt gatggatggc tagtttaaag gagctgggca
     5281 tcctagcaat aacttcctac aggaactttg gcttgtgaag gttcaggcag ttgaactgaa
     5341 ttatgctctg agaattacca taaggaagtg ttttatgatg tgttcattgc cagggttggc
     5401 cactaagaca aagaccttaa tacagagcag tataatgaag agcccagtaa catgggtggt
     5461 attgtctgtt gcagctgagc gtggctagag gaagagtcaa tgccttctga gatgcatctt
     5521 agagttttcc atgctcttcc ttctagcagc aggtggcact gggccaaaat agtatgtaaa
     5581 acataatgga gggccaggga gatgtcccag tcggtaaagc acgagaacct gagttaggat
     5641 ccccagcatc aaggccacac atagcagtgt gctcttgtat tcccagcccg tgagaggaag
     5701 accaaaagga cccctggggc tcactgacca gccaggccag ctgagttagt aagcttcaat
     5761 tcagtgagaa aacctgtctc ataaaattag gtggagagca atgtaggtgg catctgagtt
     5821 gacctctgac cttcatatgc acaggcacat acatatacat gcacacacat ccccatacac
     5881 ataaaggaac attcatatac aaaaaatatg catgtttttc ttctcagaat aactatgtat
     5941 aagatcatga gcagggctct agtgcctcat tggcagtgtg tttgacacca tggggagtcg
     6001 cagcttctgt atcatcatcg gcctgtatca atttcccaga tggccacgct cacccttcat
     6061 tgatactctc ttcatgtgtc tgtcctctcc acgattttgg atgatgtcat cacaatgatc
     6121 tcctggtcat atcacagtcc actcgtcaca ttcctgttgt ctgtcttaat gacacatgtc
     6181 actgcttaag tttcctgatc catcacaagg tctacatctc ttttctttgg aatgtgtaag
     6241 ggcagcggat gcagggaccc tacccacctc actgtggctc atcagacagt cagaacattc
     6301 cagttggtta agttggctcc ccaaactgtt atctttgcat cctatagtag caaaatatag
     6361 atctaaccta acctatgctc aggtttaaac aggctgccag ttctagtcag cagcactaga
     6421 gaagccctct taagtccatt agtcactaac cttgaaggat ggaatggaaa aggagtttcc
     6481 cagaagtttc cagactttaa ctacaaggtc accttttgga gatgtgtagt attgcggcag
     6541 ggaaggcaca ttaatgtcga atagggtcat tagtgtgttc ttccttcaga tgtggtggac
     6601 ggatcttagc tgcgtgattg aagaaaatgg gtgttgctgt agaacagcat gccatgcagt
     6661 gaatggcaga gctctaagct tacagccgcc ttggaggaca attgaatagc atcacgaatc
     6721 caatgtaccg ccttttcaac cagcagtgcc acatatagga acttttctta tgtacagaaa
     6781 cttttattaa agtaacgttt gtaataacaa aaggttagaa actaccatta attcagaaca
     6841 gaggtgaaaa aatatcatgg cccatatcta caatggggca ttttgcagac acttaaaaga
     6901 atagacctgc tctgtgtatt gccaaggaac gttcaaggga tcttggagcc acatggttaa
     6961 gtgggggaag aaaacatgca tgaacatgca tgaagtgcta gtgtttggaa tagagataaa
     7021 tacatgtaaa tgtgtggatg catatgtgtg tgcgcgcata tactcacaca tatgcttgtg
     7081 atacgtctgc ttgcctgttc ccagactgtc tctgagaagt gacacagcag cctggcagcc
     7141 tcagttgccg cctagaagaa ggtggaaatg acttttcacc gtttgccttt tgtactctgg
     7201 aattttgtac cgtgtacatg cattatctac tcaaataaat agtttttgaa gtttaaaaaa
     7261 aaaaaaaaaa aa
//
