LOCUS       NM_001418046            2266 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus coiled-coil domain containing 92 (Ccdc92), transcript
            variant 2, mRNA.
ACCESSION   NM_001418046 XM_006504287
VERSION     NM_001418046.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2266)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2266)
  AUTHORS   Zuo,F., Wang,Y., Xu,X., Ding,R., Tang,W., Sun,Y., Wang,X.,
            Zhang,Y., Wu,J., Xie,Y., Liu,M., Wang,Z. and Yi,F.
  TITLE     CCDC92 deficiency ameliorates podocyte lipotoxicity in diabetic
            kidney disease
  JOURNAL   Metabolism 150, 155724 (2024)
   PUBMED   37952690
REFERENCE   3  (bases 1 to 2266)
  AUTHORS   Ren,L., Du,W., Song,D., Lu,H., Hamblin,M.H., Wang,C., Du,C.,
            Fan,G.C., Becker,R.C. and Fan,Y.
  TITLE     Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity
            and insulin resistance in mice
  JOURNAL   iScience 26 (1), 105769 (2022)
   PUBMED   36594018
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2266)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (bases 1 to 2266)
  AUTHORS   Jerome-Majewska,L.A., Achkar,T., Luo,L., Lupu,F. and Lacy,E.
  TITLE     The trafficking protein Tmed2/p24beta(1) is required for
            morphogenesis of the mouse embryo and placenta
  JOURNAL   Dev Biol 341 (1), 154-166 (2010)
   PUBMED   20178780
REFERENCE   6  (bases 1 to 2266)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   7  (bases 1 to 2266)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164649.4.
            
            On Mar 15, 2023 this sequence version replaced XM_006504287.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR3363660.834867.1,
                                           SRR7652917.947381.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-203               AC164649.4         131438-131640       c
            204-350             AC164649.4         109350-109496       c
            351-392             AC164649.4         108632-108673       c
            393-2266            AC164649.4         104107-105980       c
FEATURES             Location/Qualifiers
     source          1..2266
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 63.85 cM"
     gene            1..2266
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /note="coiled-coil domain containing 92"
                     /db_xref="GeneID:215707"
                     /db_xref="MGI:MGI:106485"
     exon            1..203
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /inference="alignment:Splign:2.1.0"
     exon            204..350
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..1165
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 92"
                     /protein_id="NP_001404975.1"
                     /db_xref="GeneID:215707"
                     /db_xref="MGI:MGI:106485"
                     /translation="MAATNLENQLHSAQKNLLFLQREHASTLKGLHAEIRRLQQHCTD
                     LTYELTLKSFELTGDSSSRTTELKRRCEELEAQLKAKEEENRKLLQELEQKNAAIAVL
                     ENTVREREKKYLEELKVKSHKLSMLSGELEQRASTVAYLTSQLHAAKKKLLSSSGTSD
                     ASPAGSPALASYKPTPPKDKLPETPRRRMKKSLSAPLHPEFEEVYRFGAESRKLLLRE
                     PVDAMPDPTPFLLARESAEVQLKERPLVIPPIASDRSATGQHSPARDKPHKTHVGVAH
                     RIHHATPSQAQPEGEMRAVDQVNASKVVRKHSGTDRTV"
     exon            351..392
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /inference="alignment:Splign:2.1.0"
     exon            393..2266
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1680..1685
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /note="hexamer: AACAAA"
     polyA_site      1704
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /note="major polyA site"
     regulatory      2242..2247
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
                     /note="hexamer: AATAAA"
     polyA_site      2266
                     /gene="Ccdc92"
                     /gene_synonym="D5Bwg0834e"
ORIGIN      
        1 aggctgcgca ccggcgcggc gggggaggcg cggcgcaacg gctgcaaccg ccggcccggg
       61 ccgggtacga gccgcattgc gggtgcgggg cagcgccccg gggtccggcc ccaagccggc
      121 gggatgctgc gggcctcagc cgcctgcccg cgtcacacct gccgcctccc ggacctgcag
      181 ctctggcgac cgggtggctc cgcgtcacct ggatgtcagc atggcagcca caaacctgga
      241 gaaccagctg cacagtgcac agaagaacct gctcttcctc cagcgggagc acgccagcac
      301 actcaagggg ctgcacgccg agatccggcg gctgcagcag cactgcacag atctaacata
      361 tgagctgaca ctcaaaagtt tcgaactgac aggagacagc tcttccagaa cgacggagct
      421 gaagaggcgc tgtgaggagc tggaagccca gctgaaggcc aaagaggagg aaaaccgcaa
      481 gctgctgcag gaactggaac agaagaacgc cgccatcgct gtgctggaga acacagtccg
      541 tgagagagag aagaagtacc tggaggagct gaaggtgaag agccacaaac tgagcatgct
      601 gtcaggtgag ttggagcaac gcgccagcac tgtggcctac ctcacctcgc agctgcatgc
      661 agccaagaag aagttgctga gctcaagtgg cacctcggat gccagccctg ccggcagtcc
      721 cgcgctggcc agctacaaac ccacaccccc caaggacaag ctgcctgaga caccccgccg
      781 ccgcatgaag aagagcctgt ccgccccact gcaccccgag tttgaggagg tctacaggtt
      841 tggagccgag agccgcaaac tcctccttcg ggagcctgtg gatgccatgc ccgaccccac
      901 cccattcctg ctggcccggg agtctgctga ggtccagctc aaggagcggc ctctcgtcat
      961 ccctcccatt gcctcagatc gtagcgccac tgggcagcac agcccagccc gagataagcc
     1021 acacaagacg catgttgggg tggctcaccg cattcatcat gccactccat cacaggccca
     1081 gcctgaggga gagatgaggg ccgtggacca ggtgaatgca agcaaggtgg tgcggaagca
     1141 ctcagggaca gaccgaactg tgtgaggcct gcggcctgcc accgcagtca tccacgcact
     1201 gtgagcgcca cagggaacct cctcgcccac accttcctcg cctacccatg ccaaatgtct
     1261 cctcctgtcg aaacctggct cctggctcca tagtgacaca atgctacaat ggtgtccccg
     1321 ctgaagatat tactggcact gtggccaacg cctgcatgcc aatagcttgc ttctagcccc
     1381 acgccatgag atcttggcgc actcctagat acagccatgg ctgaatcact atgccaccta
     1441 gaatatgaat cgcctgaagt caaagcagag aaggagctat ccctccacag atccaggaca
     1501 gcctatgaga gcagagcagc agcctcggct ccctcctgga gacccctgcc ctgcacagtc
     1561 cctttaccaa gcagctgtgg ctcctgatct tagcaagatg acctcaaccc tgatgttgcc
     1621 ccaacctgat tgtgtgttca taattttttt tgttagtttc atccagatgt tcaggatcca
     1681 acaaatgtta ttttctaaac ccgccctcct tttcctccga gtctttttga agcaccgagg
     1741 gactgtggag gaggtggtcg gggaggacga agcaggtggg gtgggaggac ttgctgccca
     1801 gagctgttgc tgagattgtt aatgctcctg cgtttctggc agaagctgca ttctgtcctg
     1861 cccaggcgct gcctccctgt ctcacagtgt aagagacgca gccagtggcc atttgtccca
     1921 aggccacaca gagaagaggt ctggagctcg ggcaggaact gaacgcttga gcctctgtgc
     1981 tcttgccgga aggagccatg tgccggagca gccggaggtg gatccccaca ccagtggctt
     2041 agcaggaagg gagggagaat gaatgcactt gccttaaaac tcgctctggc gtgtgctcta
     2101 tccagagttc tctatacaag aagcttggga agctgaggcc aaccccagca cccacgtggt
     2161 gcctcacaat tagctgtaac tccagggacc accttacagg tggtgcacgt atattcaggc
     2221 aggctctcac acatacacag aaataaaatc ttaaaaaaaa taaaaa
//
