LOCUS       NM_001081291            4959 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 88B (Ccdc88b), mRNA.
ACCESSION   NM_001081291 XM_887102
VERSION     NM_001081291.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4959)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4959)
  AUTHORS   Olivier,J.F., Langlais,D., Jeyakumar,T., Polyak,M.J., Galarneau,L.,
            Cayrol,R., Jiang,H., Molloy,K.R., Xu,G., Suzuki,H., LaCava,J.,
            Gros,P. and Fodil,N.
  TITLE     CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic
            cell function in neuroinflammation and colitis
  JOURNAL   Commun Biol 7 (1), 77 (2024)
   PUBMED   38200184
  REMARK    GeneRIF: CCDC88B interacts with RASAL3 and ARHGEF2 and regulates
            dendritic cell function in neuroinflammation and colitis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4959)
  AUTHORS   Olivier,J.F., Fodil,N., Al Habyan,S., Gopal,A., Artusa,P.,
            Mandl,J.N., McCaffrey,L. and Gros,P.
  TITLE     CCDC88B is required for mobility and inflammatory functions of
            dendritic cells
  JOURNAL   J Leukoc Biol 108 (6), 1787-1802 (2020)
   PUBMED   32480428
  REMARK    GeneRIF: CCDC88B is required for mobility and inflammatory
            functions of dendritic cells.
REFERENCE   4  (bases 1 to 4959)
  AUTHORS   Fodil,N., Moradin,N., Leung,V., Olivier,J.F., Radovanovic,I.,
            Jeyakumar,T., Flores Molina,M., McFarquhar,A., Cayrol,R., Bozec,D.,
            Shoukry,N.H., Kubo,M., Dimitrieva,J., Louis,E., Theatre,E.,
            Dahan,S., Momozawa,Y., Georges,M., Yeretssian,G. and Gros,P.
  TITLE     CCDC88B is required for pathogenesis of inflammatory bowel disease
  JOURNAL   Nat Commun 8 (1), 932 (2017)
   PUBMED   29030607
  REMARK    GeneRIF: A critical function of CCDC88B in colonic inflammation
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4959)
  AUTHORS   Kennedy,J.M., Fodil,N., Torre,S., Bongfen,S.E., Olivier,J.F.,
            Leung,V., Langlais,D., Meunier,C., Berghout,J., Langat,P.,
            Schwartzentruber,J., Majewski,J., Lathrop,M., Vidal,S.M. and
            Gros,P.
  TITLE     CCDC88B is a novel regulator of maturation and effector functions
            of T cells during pathological inflammation
  JOURNAL   J Exp Med 211 (13), 2519-2535 (2014)
   PUBMED   25403443
  REMARK    GeneRIF: These results identify CCDC88B as a novel and important
            regulator of T cell function.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC120557.12.
            
            On Feb 6, 2007 this sequence version replaced XM_887102.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC151009.1, SRR13422601.999599.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               AC120557.12        140767-140898
            133-290             AC120557.12        141187-141344
            291-402             AC120557.12        141483-141594
            403-472             AC120557.12        141672-141741
            473-531             AC120557.12        141821-141879
            532-615             AC120557.12        141968-142051
            616-759             AC120557.12        142726-142869
            760-908             AC120557.12        142988-143136
            909-990             AC120557.12        143245-143326
            991-1149            AC120557.12        143464-143622
            1150-1296           AC120557.12        144090-144236
            1297-1405           AC120557.12        144391-144499
            1406-1542           AC120557.12        144654-144790
            1543-2703           AC120557.12        144876-146036
            2704-2831           AC120557.12        148406-148533
            2832-2949           AC120557.12        148605-148722
            2950-3045           AC120557.12        148981-149076
            3046-3186           AC120557.12        149154-149294
            3187-3443           AC120557.12        149747-150003
            3444-3587           AC120557.12        150294-150437
            3588-3774           AC120557.12        150610-150796
            3775-3920           AC120557.12        150899-151044
            3921-4019           AC120557.12        151244-151342
            4020-4186           AC120557.12        151535-151701
            4187-4393           AC120557.12        152209-152415
            4394-4462           AC120557.12        152563-152631
            4463-4959           AC120557.12        153859-154355
FEATURES             Location/Qualifiers
     source          1..4959
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 5.08 cM"
     gene            1..4959
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /note="coiled-coil domain containing 88B"
                     /db_xref="GeneID:78317"
                     /db_xref="MGI:MGI:1925567"
     exon            1..132
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..4518
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /note="hkRP3; hook-related protein 3; coiled-coil domain
                     containing 88; gipie"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 88B"
                     /protein_id="NP_001074760.1"
                     /db_xref="CCDS:CCDS37900.1"
                     /db_xref="GeneID:78317"
                     /db_xref="MGI:MGI:1925567"
                     /translation="MEGAKGPRLRGFLSGSLATWALGLAGLVGEAEESAGGTEEEEEE
                     EEEEGALCTEKRFLRLIDGALLLRVLGIIAPSSRGGLRMVRGRDGPAACRMWNLCHLW
                     GRLRDFYQEELQLLILSPPPDLQTMGCDPFSEEAVDELESILRLLLGASVQCEHRELF
                     IRHIRGLSLDVQSELAGAIQEVTQPGAGVVLALAGPESGELVAEELEMQLRSLTGMMS
                     RLARERDLGAQRLAELLLEREPAHLLLPEAPANASAEGVSHHLALQLTNAKAQLRRLR
                     QEVEEKAEQLLDSQAEVQGLEAEIRRLRQETQALSAQAKRAELYREEAEALRERAGRL
                     PRLQEELRRCREKLQAAEVFKGQLEEERVLSEALEASKVLLEEQLEVARERSARLHET
                     QRENLLLRTRLGEAHADLDSLRHQLEQLVEENVELELELQRSLEPPPGSPGEASLPGA
                     APSLQDEVREAEAGRLRAVERENRELRGQLQMLQAQLGSQHPLLEEQRENSRQPPVPN
                     RDPATPSALHHSPQSPACQIGGEGSESLDLPSPASYSDITRSPKCSQAPDSHPELESP
                     LQMVSQDPQTSDQALQESDPTVETHQCLEKSGHRVPLQSPIVWDPPQGPEVRIEVQEL
                     LGETGSREAPQGELVHKAQVLKQESPKCRPRSAELTLREPLKDQKALDRELELSKQQK
                     ETGRHEQRPKGLESKLGPQKPQQTSEGVPDAWSREEPTPGETLVSAIPEEQALRDEVA
                     QLRREVAGLEVKLQAQAQRLEARSAEALCLSEELAQARRTEAEAHQEAEAQAREQARL
                     REAVDTASLELEAASREREALAEALAAAGRERRQWERDGPRLRAQVEAAEQQVQALES
                     QVRCHLEEAEREHAEKQALREELEKAVLRGQELGDRLEHLQEELEQAALERQKFLQEQ
                     ENQHQRYRHLEQRLEAELQAASTSKEEALMELKARALQLEEELIQLRQYPVDLATGAR
                     AGPRTVETQNGRLIEVERNNATLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRA
                     QEHSSRLQAEKSMMEMQGQELHRKLGVLEEEVRAARRAQEETRGQQQALLRDHEALVQ
                     LQRRQETELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRANVEAQEVALLAER
                     ERLMQDGHRQRGLEEELRRLQNEHERAQMLLAEVSRERGELQGERGELRSRLARLELE
                     RAQLEIQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRENR
                     ELLERSLESRDHLHREQREYLDQLNALRREKQKLVEKIMDQYRVLEPGPLPRTKKGSW
                     LADKVKRLIRPRREGALHGGPRLGADGAGSTESLGGPLETELPEGREADGTGSSSPAP
                     MRRVQSSLCLGDETLAGGQRRRLSSRFPGGRSSASFSPGDTPRQRFRQRRPGPLGAPS
                     THSKGSGVEWDGSIKTLSEHEADDTREAFQEQKPEKQFLTPSLSQ"
     exon            133..290
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            291..402
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            403..472
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            473..531
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            532..615
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            616..759
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            760..908
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            909..990
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1149
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            1150..1296
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1405
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1542
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            1543..2703
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            2704..2831
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            2832..2949
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            2950..3045
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            3046..3186
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            3187..3443
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            3444..3587
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            3588..3774
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            3775..3920
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            3921..4019
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            4020..4186
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            4187..4393
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            4394..4462
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     exon            4463..4959
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4933..4938
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /note="hexamer: AATAAA"
     polyA_site      4959
                     /gene="Ccdc88b"
                     /gene_synonym="2610041P08Rik; Ccdc88"
                     /note="major polyA site"
ORIGIN      
        1 ggggacttcc tcttcctctc agagcaggtg tagctgccac agcgtgacag ggactacacc
       61 ctgaccccca acatggaggg ggccaagggg cccaggctca gaggctttct gagtgggagt
      121 ctggccacct gggcactggg actggctggg ctggtggggg aggcagaaga atcagcgggg
      181 ggaacagagg aggaggagga ggaggaggag gaagaggggg ctctttgtac agagaagaga
      241 ttcctgcggc tgatcgatgg agccttactc cttcgggtgc tgggcatcat tgctcccagt
      301 tcccgaggag gacttcgaat ggtcaggggc cgtgatggtc ctgcagcctg tcggatgtgg
      361 aacctctgtc atctatgggg gcgactgagg gatttttacc aggaggagct acagctgctg
      421 atcctatcac cacctccaga cctccagaca atggggtgtg accccttctc agaagaggca
      481 gtggacgagc tggaaagcat ccttcggctg ttgctggggg cctcagtgca gtgtgaacac
      541 cgggagctct tcatccgtca catccggggc ctcagccttg acgtccagag cgagctggct
      601 ggtgcaatcc aggaggtgac ccaacctggt gctggtgtgg tactggctct ggctggacca
      661 gaatccggag agctggtggc tgaggagctg gagatgcagt tacggagcct gacagggatg
      721 atgtccaggc tggcgcggga gcgcgatctg ggggcacagc ggttggctga actgctgcta
      781 gagcgggagc cagcccactt gctgctgcca gaggctcctg ctaatgcgtc tgcggagggt
      841 gtctcgcacc atctggctct gcagctgacc aatgccaagg cccagctgag acgcctgagg
      901 caggaggtgg aggagaaggc tgagcaactg ctggactccc aggccgaggt gcagggcttg
      961 gaggctgaaa ttcgaaggct ccgccaggag actcaggcgc tgtccgcaca agccaagcgc
     1021 gcagagctct accgcgagga ggcagaggca ctgcgggagc gggccggccg cctgccacgc
     1081 ctgcaggaag aactgcggcg ctgtcgcgag aagcttcaag ctgcagaggt cttcaagggt
     1141 cagctggagg aggagcgggt cctttccgag gccctggagg cctcgaaggt cctgctagag
     1201 gaacagctgg aggttgcccg agagcgctca gccaggctgc atgagaccca gagggagaac
     1261 ctcctgctgc gcacgcggtt gggcgaggcc catgcggacc tggactctct gcggcatcag
     1321 ctggagcagc tggtggaaga gaatgtggag ctggagctgg aacttcagag gagtctggag
     1381 ccacccccag gctcccctgg ggaggcctcc ctacccggag cagcaccctc actgcaagat
     1441 gaggtgaggg aagcagaggc tgggaggcta agggcagtgg aacgggagaa ccgggagctt
     1501 cgaggccaac tacagatgct tcaggcacag cttggcagcc agcaccctct gctggaggag
     1561 cagagggaga actccaggca gccacctgtg cctaacaggg atccagcaac tccctcggcc
     1621 ctccatcaca gcccccaaag ccccgcttgc cagataggag gtgaaggctc cgaatctttg
     1681 gacctgcctt ctccagcatc atactctgac atcacaaggt cacccaagtg ttctcaggca
     1741 cccgactcac acccagagtt ggagagtcct ctccagatgg tatctcagga tccccagacc
     1801 tcagaccaag ctctccaaga atcagaccct actgtggaga cacatcagtg cctggagaag
     1861 tctggtcata gagtccctct ccagagtccc atcgtctggg acccaccaca gggtccagag
     1921 gtcagaattg aagtgcagga gttgctagga gagactggaa gcagggaggc tccccaaggg
     1981 gagttggtac acaaggccca ggtcctaaaa caagagagcc ccaaatgcag gcccagatct
     2041 gctgagctca ccctccggga gcctctgaag gaccagaagg ccctggatcg ggaactagaa
     2101 ctatccaagc aacagaaaga gacaggaagg catgaacaga ggcccaaggg gttggagagt
     2161 aaactgggcc ctcagaaacc acagcagaca tcagaagggg tgcctgatgc ctggtccagg
     2221 gaggagccaa ccccggggga gaccctggtc agtgctatcc cagaggagca ggccctcaga
     2281 gatgaggtag cacaactaag gagagaggtt gcaggccttg aggttaaact gcaagcccaa
     2341 gcccaaagac tggaggcccg aagtgcagag gctctctgcc tctctgagga gctggcccaa
     2401 gctcgcagaa cagaggcgga ggcccatcag gaggcagagg cccaggcccg ggagcaggcc
     2461 cgtctgcgtg aagcagtgga tacggctagc ttggagctgg aggctgcatc tcgtgagagg
     2521 gaggccctgg cagaggcact agcagcagca ggcagggagc gaaggcagtg ggaacgtgac
     2581 gggcccaggc tgcgggctca agttgaggct gccgagcagc aggtgcaggc tctggagagc
     2641 caggtccgct gtcatctgga ggaagctgag agggaacatg cggagaaaca agcccttcgg
     2701 gaggagctag agaaggctgt gctacggggc caggaactgg gggaccggct ggagcatctg
     2761 caggaggagc tagaacaggc agccttagag cgccagaagt tccttcaaga acaggagaac
     2821 cagcaccaga ggtaccggca tctggagcag cgtctggaag ctgagctgca ggcagcgtct
     2881 accagtaagg aggaggcact gatggagctc aaggctcgag ccctgcagct ggaggaggag
     2941 ctgattcagc tgcgccagta cccggtggac ctggcaactg gggcgcgagc tgggcctcgg
     3001 actgtggaga cccagaatgg acggctcatc gaagtggagc gaaataatgc cacactggtg
     3061 gctgagaagg cggctctgca ggggcagctg cagcacctgg aggggcagct ggggagcctg
     3121 cagggccgtg cacaggagct cctgctacag agtcagcggg ctcaggagca cagcagtcgc
     3181 ctgcaggctg aaaagtcaat gatggagatg caaggtcagg agctgcatag gaagctgggg
     3241 gtgctagaag aggaggtgcg ggcagcaaga cgggcccagg aggagacccg agggcagcag
     3301 caggctctgc ttcgggacca tgaggccttg gtgcagctgc agcgacggca ggagacggag
     3361 ctggagggac tgttggtgcg gcaccgagat ctcaaggcca atatgcgagc attggagctg
     3421 gcccaccgtg agcttcaggg ccggcatgag cagttgcagg cccaacgggc caatgtggaa
     3481 gcacaagagg tagccctact ggcagagcgt gagcgcctga tgcaggatgg acatcggcag
     3541 cgcggcctgg aggaggagct gcggagactt cagaatgagc acgagagagc tcagatgcta
     3601 ctggccgagg tgtcccggga gcgaggggag ctccaaggtg aacgcgggga gctgcggagc
     3661 cgcctggcga ggctggagct ggagcgcgca caacttgaga tccagagcca gcagctgcgt
     3721 gagtccaacc agcagttgga cctgagtgcc tgtcgtctga ccacacagtg tgagcttctg
     3781 acccagcttc gcagcgcgca ggaggaggag aacaggcagc tgttagccga ggtccaggcc
     3841 ctgagccggg agaacaggga gctgctggag cgcagcctgg agagccgcga ccatctgcat
     3901 cgagagcagc gagagtacct ggaccagctt aatgccttgc gccgggagaa acagaagctg
     3961 gtggagaaaa tcatggacca gtaccgtgtg ctagaacctg ggcccctacc ccgtaccaag
     4021 aagggcagct ggctggcaga caaggtgaag aggctcattc ggccccggcg ggagggggcc
     4081 ctccatgggg ggccacgcct gggggccgat ggggctggca gcacggaaag cttggggggc
     4141 cccctggaga cggagctccc tgagggcagg gaggcagatg ggacagggtc ctcgtcacca
     4201 gcacccatgc gccgcgtcca gagctctctc tgcttgggag atgagaccct ggcaggtggg
     4261 cagcggcgga gactcagttc ccggttccct ggggggcgaa gctctgcgtc atttagtcca
     4321 ggggacaccc caaggcaacg gttcagacag cgaagacccg gccccctggg ggcacccagt
     4381 acccacagca aaggatctgg tgtggaatgg gatggctcca ttaagaccct ctcggagcat
     4441 gaagcagatg acactcgaga ggccttccag gagcagaaac cggagaaaca gttccttacc
     4501 ccttccctca gccagtgatt ctgtggggac agacggctta ggcgtgcagc cttctcccca
     4561 ttgtagggtc agtggggctc ccaggcagcc caagagccgg gggaccaggg gaccccaaga
     4621 agaccccttg gacaaagagg cctgggctct caggtccccc acagcctata ctggggctct
     4681 gagaaggagc tgggacgagg ctgtggacag gggagatgat tggtccaaac cgggagctcc
     4741 tggccagggc tcttgctctg aagtacagcc ctcaccaagg agacgatccc tgggagactc
     4801 cccagctgaa gacggctggc aagagtgggc aagaaaaccc tctgccagct ctagatgggg
     4861 agctaaggcc cattccctgg ggacaggcct gggctgatat ctgagcattg tctgggacac
     4921 gagggaaaga agaataaagc tgaaacccct tgaatctgg
//
