LOCUS       NM_207268               3163 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus coiled-coil domain containing 87 (Ccdc87), mRNA.
ACCESSION   NM_207268
VERSION     NM_207268.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3163)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3163)
  AUTHORS   Wang,T., Yin,Q., Ma,X., Tong,M.H. and Zhou,Y.
  TITLE     Ccdc87 is critical for sperm function and male fertility
  JOURNAL   Biol Reprod 99 (4), 817-827 (2018)
   PUBMED   29733332
  REMARK    GeneRIF: Ccdc87 mRNA and protein were only expressed in testis.
            Ccdc87 expression first appeared at postnatal day 14 and remained
            at a relatively high level until adulthood. Male mice lacking
            Ccdc87 gene (Ccdc87-/-) were found to be subfertile.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB614818.1, AK029877.1, AC141437.4, BB667164.1 and AV275040.1.
            
            On Jun 1, 2007 this sequence version replaced NM_207268.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-647               BB614818.1         3-649
            648-851             AK029877.1         600-803
            852-2196            AC141437.4         69169-70513         c
            2197-2798           AK029877.1         2149-2750
            2799-3151           BB667164.1         305-657
            3152-3163           AV275040.1         247-258
FEATURES             Location/Qualifiers
     source          1..3163
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 4.11 cM"
     gene            1..3163
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /note="coiled-coil domain containing 87"
                     /db_xref="GeneID:399599"
                     /db_xref="MGI:MGI:3026882"
     exon            1..3163
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..2684
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 87"
                     /protein_id="NP_997151.2"
                     /db_xref="CCDS:CCDS29439.1"
                     /db_xref="GeneID:399599"
                     /db_xref="MGI:MGI:3026882"
                     /translation="MEPHSQEPDLKPIYHRLLSPLSLFPSKAKPPPEPPKRPSQDATP
                     LQSIPLAKLKVGPLCRQVSKRLASSGRAARVTAKDRLRLTEVILEELKCNWREPPIEP
                     ILDYENNQKLRQRLESYVLISSEQLFVRYLHLLVTLPTSRRVFTESATLSRLAVNLAR
                     DCTVFLTSPDVYRCLLADFQTLLNLKHAQGGIVKLRPPPCPPGTFKLCPIPWPHSTGL
                     DHMPCSSLNLNYLVQLSRPYDFPSEPEPDPVEELKSIPQLKSRQQLLWVPSMIKDKEI
                     ESRPSPMVPLPSHSPSSESHQFPTSPVHSWLQRGQSMPCLHEGWSLADELCLLPPSPH
                     PLTPLILASESKPLPFRDIVAEDLKQKMKIMRMEWSRYSLLDSGLPPLLGVLTRRLTA
                     QHHLEKLQQMIKSLQEEEASGKWDLQPPRIIPLHPQPVTVALKVHDQVIVQVATVQLS
                     ERYFNDSFHVEGAGVLYNHLTGELDGKAIEEMDADRLVGNTTGEVYKELMSRVSVSHL
                     SFEEGDQIEPSADKDWSSYLASSFLHQDKHMPIINRNLVGFYSRRTSTPKPVPEKVPS
                     LTLLPRHKSWDKRPNRHGVWMNWLKPSVSSEDYFKYLSFQESDFLHVIFQMYEKEAPV
                     EVPVPVQEYLDIQQPPPLLQDEELEFMQGKWDWSSVIEDGSGPGRAYIHNLQQRLKRL
                     WVMLEVPEQNRLDMVIKYSSNARLQQLPALIKAWEQVLKPIQKRESLLGRLEWFEQQA
                     SDPNRFFQKPDLLMNRLLEENRFRSYLQRKLNRMESNLVSLLERIESVFGEPVTFKGR
                     SYLKKMKQDKVEMLYWLQQQRRIRNLTQAQKTFRQSCTFTGSSSQALVAPGNTPTTH"
     regulatory      2784..2789
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2801
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /note="major polyA site"
     regulatory      3140..3145
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3162
                     /gene="Ccdc87"
                     /gene_synonym="4931419P11Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggctgaggc ctctgagctg tccggtagtg ctaccggctg cgcaggcgca ttgatgcagt
       61 ttccttagta accatttggc gtcctctacc cgctcagccg gaaccacctg gtaaagatgg
      121 aaccacacag tcaggaacct gacctcaagc cgatttacca ccggttgctg agtccgctgt
      181 cgctcttccc cagcaaggcg aagcctcctc cagagcctcc gaagcgcccc tctcaagatg
      241 ccacgccctt gcaatccatc ccgctggcga agctgaaagt tgggccgctg tgccgccaag
      301 tgtccaagcg gctagcaagc agcgggcggg cggcacgagt aactgccaag gaccgacttc
      361 gtctcactga ggttattcta gaagagctga agtgcaactg gcgggaacct cctatagaac
      421 ccattctgga ctacgaaaac aaccagaagc tgcggcagcg gctcgagtcc tacgtgctga
      481 tcagtagtga gcagctcttc gtacgctacc tgcacctgct ggtgaccctg ccgacctcta
      541 gaagggtctt cactgaatca gccaccctca gccggttggc agtaaacctt gccagggatt
      601 gcacagtttt cctcaccagt cctgatgtct atcgctgtct gctggctgat tttcagaccc
      661 tgctaaattt aaagcacgcc cagggaggca tagtcaaatt gcgtcctcct ccctgtcccc
      721 ctgggacttt caagctctgt ccaatcccct ggcctcacag cactggctta gaccacatgc
      781 cgtgctctag cctcaacctg aactaccttg tccaactcag ccgcccatat gatttcccca
      841 gtgagcccga acctgatcca gtggaagagt tgaaatccat cccccagctg aagagtagac
      901 agcagctcct ctgggtgccc tccatgataa aggataaaga aattgaatcg agaccctcac
      961 cgatggtacc actgcctagt cattctccca gcagtgagag tcaccaattc cccacctcac
     1021 cagtccattc ctggctccaa aggggccagt ccatgccttg tcttcatgag gggtggagtc
     1081 tggcagatga gttgtgcctt cttcctccct ctcctcatcc cctcaccccg ctgatcttgg
     1141 cttcagagag taaaccactg ccattccggg acatagtggc tgaggatctg aagcagaaaa
     1201 tgaagatcat gagaatggag tggagtcgat actccctgct ggactctggc ctgcctcccc
     1261 tcctcggggt ccttacccgg cgcctaactg cccagcacca cctagagaaa ctgcagcaaa
     1321 tgatcaaaag cctgcaggag gaagaagcct ccggaaagtg ggatctccaa cccccgagaa
     1381 tcatcccact acacccacag ccagtcactg ttgctttgaa ggtacatgat caagttatag
     1441 tccaggtagc tactgtgcaa ctctctgaaa gatactttaa cgactctttc cacgttgagg
     1501 gggctggagt cctatacaac catctgactg gggaactgga tggtaaagcc attgaagaaa
     1561 tggatgcgga tcgtcttgtt gggaacacca ccggagaggt ctacaaggag ttgatgagcc
     1621 gagtctctgt tagtcactta tcttttgagg aaggagacca aattgagcct tcagcagata
     1681 aagattggtc ctcctacttg gcctcatctt ttctacacca agataaacat atgccaatca
     1741 tcaaccgtaa tctggttgga ttttactcca gaagaacaag cactccgaag ccagtccctg
     1801 agaaggtgcc ctctctcaca ttactcccaa ggcacaaaag ctgggacaag cgaccaaaca
     1861 gacacggtgt atggatgaat tggctgaaac cctcggtgtc ttcagaggac tacttcaagt
     1921 acctctcctt tcaggagtcg gatttcctcc acgtcatctt ccaaatgtat gaaaaagagg
     1981 ctcctgtgga ggtaccagtc cctgtccaag agtacctaga tattcagcaa ccccctcccc
     2041 tgctgcaaga tgaagagcta gagttcatgc aaggaaaatg ggattggagc tcagtgatag
     2101 aggatggctc aggacctggg agagcctaca ttcataactt gcagcagcgt ctcaaacgac
     2161 tgtgggtcat gttggaagtc cctgaacaga atcggctaga catggttatt aaatacagct
     2221 ccaatgcacg cctgcaacag ctaccagcat tgatcaaggc ttgggagcag gtcctgaagc
     2281 ccattcaaaa gagggagtcg ttgctaggaa gactggagtg gtttgagcaa caagcctctg
     2341 atcccaatcg tttcttccaa aagcctgatt tgttgatgaa tcggttactg gaggagaatc
     2401 ggttccgtag ctatctccaa aggaagctca atcgaatgga atctaatttg gtttccttgt
     2461 tggaaaggat agagtcagtc tttggggagc cagtgacctt caaggggcgg agctatctga
     2521 agaagatgaa gcaggacaaa gtggagatgc tgtactggct ccagcagcag cggcggattc
     2581 gcaatctgac ccaggcccag aaaaccttcc gccaatcatg cactttcaca gggagcagca
     2641 gccaggcgtt agtggccccc gggaatactc ccactactca ctaaggcggc caagtgcccc
     2701 caaacccttc ctcaccccca aatgctcacg tagaactctc aatgacttta aaagagattg
     2761 agattctttt tcttgatatt ctaaataaaa ggatccccaa acttggtatt cccatgtatg
     2821 tcaaccatcc tgcacaagac aaccaaaatc ctatatcaga tgatcccttg gagttcgtga
     2881 taatagaggt cagacagagc aagccatggt ccttaaaaaa atatatagtg actttctcac
     2941 tgtgctgaat tgctgtttag agtgccaaat cactcttgtt taggcccagt agcataatcc
     3001 ttgattgcta gggctctgaa attaacagat gtatgtatat cctgcctgta tgacttatgg
     3061 taagtcacct aacttctctg tgaggatctg ggtccatgtt gtcacttcta gtgcttacac
     3121 attgttggca ggacttgtta ataaaaccac ttggtatatc aag
//
