LOCUS       NM_023731               3003 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus coiled-coil domain containing 86 (Ccdc86), mRNA.
ACCESSION   NM_023731
VERSION     NM_023731.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3003)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3003)
  AUTHORS   Georgas,K., Rumballe,B., Valerius,M.T., Chiu,H.S.,
            Thiagarajan,R.D., Lesieur,E., Aronow,B.J., Brunskill,E.W.,
            Combes,A.N., Tang,D., Taylor,D., Grimmond,S.M., Potter,S.S.,
            McMahon,A.P. and Little,M.H.
  TITLE     Analysis of early nephron patterning reveals a role for distal RV
            proliferation in fusion to the ureteric tip via a cap
            mesenchyme-derived connecting segment
  JOURNAL   Dev Biol 332 (2), 273-286 (2009)
   PUBMED   19501082
REFERENCE   3  (bases 1 to 3003)
  AUTHORS   Saint Fleur,S., Hoshino,A., Kondo,K., Egawa,T. and Fujii,H.
  TITLE     Regulation of Fas-mediated immune homeostasis by an
            activation-induced protein, Cyclon
  JOURNAL   Blood 114 (7), 1355-1365 (2009)
   PUBMED   19528538
  REMARK    GeneRIF: Regulation of Fas-mediated immune homeostasis by an
            activation-induced protein, Cyclon.
REFERENCE   4  (bases 1 to 3003)
  AUTHORS   Hoshino,A. and Fujii,H.
  TITLE     Redundant promoter elements mediate IL-3-induced expression of a
            novel cytokine-inducible gene, cyclon
  JOURNAL   FEBS Lett 581 (5), 975-980 (2007)
   PUBMED   17300783
  REMARK    GeneRIF: cyclon gene encodes a phosphorylated nuclear protein
            consisting of repetitive sequences in the amino-terminus and a
            coiled-coil domain in the carboxyl-terminus
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK078455.1, AK036812.1 and AC148991.2.
            
            On Jan 17, 2008 this sequence version replaced NM_023731.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK036812.1, AK078407.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-307               AK078455.1         2-308
            308-527             AK036812.1         298-517
            528-1654            AK078455.1         529-1655
            1655-1932           AK036812.1         1646-1923
            1933-1933           AC148991.2         111788-111788
            1934-3003           AK036812.1         1925-2994
FEATURES             Location/Qualifiers
     source          1..3003
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 7.41 cM"
     gene            1..3003
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /note="coiled-coil domain containing 86"
                     /db_xref="GeneID:108673"
                     /db_xref="MGI:MGI:1277220"
     exon            1..989
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1314
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /note="cyclon; mCyclon; cytokine-induced protein with
                     coiled-coil domain"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 86"
                     /protein_id="NP_076220.2"
                     /db_xref="CCDS:CCDS29593.1"
                     /db_xref="GeneID:108673"
                     /db_xref="MGI:MGI:1277220"
                     /translation="MDTPLRRSRRLEGLKPLSPENLPVPEVSRAKRALVDFKSNSEET
                     GELKSTRVPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGP
                     QPETSPGSPCPPLSLPSPGPQPETSPGSPCPPLSLPSPGPQPEASPGSPGPRQDADDG
                     SPQRQPEPHPGSLQPHQDLGLESPAGQTESSPESPQREQPSKLPPPQGELDSEAAHAK
                     EEVIPGSPEPCPGQQAPGPEPSQPAQELTVQAPSSPERQLEPGKLPPAGETVTESLNL
                     KKRVIASPQAPASKKLKEKEELPVIPKGKPKSGRVWKDRSKKRFSQMVQDKPLRTSWQ
                     RKMKERQERKLAKDFARHLEEEKQRRRQEKKERRAENLRRRLENERKAEIVQVIRNPA
                     KLKKAKKKQLRSIEKRDTLALLQKQPPQRPVAKV"
     exon            990..1119
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1194
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /inference="alignment:Splign:2.1.0"
     exon            1195..3003
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2079..2084
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /note="hexamer: AATAAA"
     polyA_site      2096
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /note="major polyA site"
     regulatory      2977..2982
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
                     /note="hexamer: ATTAAA"
     polyA_site      2996
                     /gene="Ccdc86"
                     /gene_synonym="4933411H20Rik; 6720480F16Rik; D19Ertd678e"
ORIGIN      
        1 agttccgaag gctacagagg ctacacgtga gccatggata cgccgctgag gcgcagccgg
       61 cggctggaag gcctaaaacc tctgtctcca gaaaaccttc ctgtccccga agtctctcgg
      121 gcgaaacggg ctcttgtaga tttcaagtcg aactcagaag aaacaggaga gctcaagtct
      181 acgagagttc caccactgag ccttccgtct cccggacctc agccggagac gagccccgga
      241 tcgccctgtc caccactgag ccttccgtct cccggacctc agccggagac gagccccgga
      301 tcgccctgtc caccactgag ccttccgtct cccggacctc agccggagac gagccccgga
      361 tcgccctgtc caccactgag ccttccgtct cccggacctc agccagagac gagccccgga
      421 tcgccctgtc caccactgag ccttccgtct cccggacctc agccagaggc gagccccgga
      481 tcacccggtc ctagacagga tgcagacgat gggtccccac aaaggcagcc agagcctcac
      541 cccgggtccc ttcaacctca tcaagatctg ggcctggagt cacctgcagg acagacagag
      601 tcgagcccgg aatccccgca acgagagcag ccatccaaat tacctccccc acagggagaa
      661 ctggactctg aggcggccca cgctaaagag gaggtgatcc caggatcccc cgagccttgc
      721 ccgggccagc aagcaccggg tcccgagccc tctcagccag cacaggagct gacggtccag
      781 gcacctagct ccccagagcg ccagttggag ccaggcaagc tgcctccggc gggagagaca
      841 gtaacagaaa gtctcaacct aaagaagcga gttatagcct ctccccaggc cccagcgtcc
      901 aagaaattga aagagaagga ggagcttcct gtaattccga aagggaagcc caaatccggg
      961 cgtgtgtgga aagaccgctc caagaagagg ttctcccaga tggttcagga caagcccctg
     1021 cgtacctcct ggcagcggaa gatgaaggag cgacaggaga gaaagctggc taaggacttc
     1081 gcccgacacc tggaggagga gaaacagagg cgccggcagg agaagaaaga gcgccgggct
     1141 gaaaacctga gacgccgtct agaaaatgag cgcaaggctg agattgtcca agtgatccgc
     1201 aatcctgcca agctcaagaa agcaaagaag aagcagttgc gttctattga aaaacgagac
     1261 accctggcct tgctccagaa acagccaccc cagaggcctg tagccaaggt ctgagttcag
     1321 gacagtccat aggcctcagc aaacaaggca cttctcaggc cactgactga cacctctcct
     1381 ggagccagca caccaacgct gtcacattaa gacggagact ccagcccaga gggaactgac
     1441 gactatgctg ggactcaaga gagatttaac tgtccccatc tcctttcccg cctgttccaa
     1501 agtgccttat agtcataaac tgttgctggg tggttgcagc aatgcacacc ttttatcccc
     1561 gtgctcagga gacagagaca ggcagctctc agagttcgag gccagtcttg tctatagagt
     1621 acaggatagc cagggctaca cagagaagtc gtatctaaaa aaaaaaaaaa tcaaaacaac
     1681 aaaagaggtc ttcagctgtg aattcttgtt tcccagtgag ctaataaatc cctgacttgg
     1741 ggtcctgggt gttacccacg cctgaaggtc tgctgtcaga agtcagtacc tccatttttt
     1801 cagtgacatc ttggccactt gtggattcta ctgatttggt cccctcagtc aactgaagct
     1861 agcctttccc tagtttagca ctaaaagatt aaagtagggt gttacaggga gctgagtttc
     1921 tctccagcac ccctttgcca cactggactg tagaagcctc gaggcttgag tcatacctac
     1981 ctgctctatt gcagaggtgt ttattggtat ctgcataagt acagctctgg gctccccgaa
     2041 ggacagaagc ccctgcccca cttggctttc attatcataa taaaccattg aaataatggt
     2101 gtgacaggta cactgagtaa agcaggaggg acttggtgac attttactct ccagtttgag
     2161 aagcgcctgc cacaggcttg aggcctgctc aacacaactg acaaccagcc tggccttgcg
     2221 tggttcagga gatcctgaga ctaccccatc cctgttccat atttaccaat ttctgacatc
     2281 agctcccctt cccctagaag gtaaagagga atcagccagc ttccctgcag tctatgatgg
     2341 ggaggacatg aaatgtgtga tagaaggtcc atgactggca caggtgcccc tcctacctgt
     2401 aggttggaag tgatggctgc caggccctct ccctgccagg cagctaataa gggtaggttg
     2461 ttctctctgc ctagaattga tccagtgctg ctgaaagcca gcagcagcag ccctaaaact
     2521 gggcagtgaa aatccctagt gggagttgac acatccatat caccatatat aacaataaca
     2581 agctgactag caaggtgtgg ttaaagcacc tgtctcaggc caaatggggg attaaaaatg
     2641 atggcagttg gctggtctca acccttttcc tctcactgac ccccataaat actgattggc
     2701 cgactccctt tgtcccattc acaaagcagg gagttatgag atgcaggctg tgagcttaac
     2761 ctgtgtgatt cccaagtgcc ttgggcgagc tgccaggaag gtaatagaaa tacaaaattt
     2821 tacccgaccc ttatcagtta ccctagcaag atccctaggc aattaagtac ttttgctctt
     2881 aaatgtgtag aaacctggag gccagcagtc aagagccagg taactcctcg atggctactt
     2941 ttgcatcttg ttgctctccc aggtccatac tgcaagatta aagtgtttta aaaggactgc
     3001 ttc
//
