LOCUS       NM_001159910            4268 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus coiled-coil domain containing 85C (Ccdc85c), mRNA.
ACCESSION   NM_001159910 XM_994648
VERSION     NM_001159910.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4268)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4268)
  AUTHORS   Xu,J., Deng,X., Gu,A., Cai,Y., Huang,Y., Zhang,W., Zhang,Y., Wen,W.
            and Xie,Y.
  TITLE     Ccdc85c-Par3 condensates couple cell polarity with Notch to control
            neural progenitor proliferation
  JOURNAL   Cell Rep 42 (7), 112677 (2023)
   PUBMED   37352102
REFERENCE   3  (bases 1 to 4268)
  AUTHORS   Mori,N., Kuwamura,M., Tanaka,N., Hirano,R., Nabe,M., Ibuki,M. and
            Yamate,J.
  TITLE     Ccdc85c encoding a protein at apical junctions of radial glia is
            disrupted in hemorrhagic hydrocephalus (hhy) mice
  JOURNAL   Am J Pathol 180 (1), 314-327 (2012)
   PUBMED   22056358
REFERENCE   4  (bases 1 to 4268)
  AUTHORS   Kuwamura,M., Kinoshita,A., Okumoto,M., Yamate,J. and Mori,N.
  TITLE     Hemorrhagic hydrocephalus (hhy): a novel mutation on mouse
            chromosome 12
  JOURNAL   Brain Res Dev Brain Res 152 (1), 69-72 (2004)
   PUBMED   15283996
REFERENCE   5  (bases 1 to 4268)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122407.4 and AC152059.4.
            
            On Feb 15, 2019 this sequence version replaced NM_001159910.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927938.2248687.1,
                                           SRR11927936.1839537.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164136
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-469               AC122407.4         93898-94366         c
            470-1056            AC152059.4         1-587
            1057-1130           AC152059.4         53143-53216
            1131-1238           AC152059.4         63303-63410
            1239-1334           AC152059.4         66996-67091
            1335-1433           AC152059.4         67705-67803
            1434-4268           AC152059.4         68491-71325
FEATURES             Location/Qualifiers
     source          1..4268
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 59.23 cM"
     gene            1..4268
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /note="coiled-coil domain containing 85C"
                     /db_xref="GeneID:668158"
                     /db_xref="MGI:MGI:3644008"
     exon            1..1056
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..1523
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 85C"
                     /protein_id="NP_001153382.1"
                     /db_xref="CCDS:CCDS49166.1"
                     /db_xref="GeneID:668158"
                     /db_xref="MGI:MGI:3644008"
                     /translation="MAKPPAVAAAAAAAASEELSQVPDEELLRWSKEELARRLRRAEG
                     EKVGLMLEHGGLMRDVNRRLQQHLLEIRGLKDVNQRLQDDNQELRELCCFLDDDRQKG
                     RKLAREWQRFGRHAAGAVWHEVARSQQKLRELEARQEALLRENLELKELVLLLDEERA
                     ALAAAGGAGGGGGGAGSRSSIDSQASLSGPLAGSAAGSGARDVGDGSSTSSAGSGGSP
                     DHHHHVPAALLPPGPHKVPDGKAGATRRSLDDLSAPPHHRSIPNGLHDPSSTYIRPLE
                     TKVKLLDGDKLPPQQAGSGEFRTLRKGFSPYHSESQLASLPPSYQEVLQNGPACPVPE
                     LPSPPSTVYSSAGQKPEAVVHAMKVLEVHENLDRQLQDSCEEDLSEKEKAIVREMCNV
                     VWRKLGDAASTKPSIRQHLSGNQFKGPL"
     exon            1057..1130
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1238
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1334
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1433
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..4268
                     /gene="Ccdc85c"
                     /gene_synonym="EG668158; Gm265; Gm9010; hhy"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctgctgcg cccgagctcg gagagccggg gcaccgcggc cgccgacgca gccacggtcc
       61 cggttcctca gtcctgaggc gtgcgcgggc tctcgggtga ccccagaggg ggccgcggga
      121 gggagcgcga ggcggcgaag ggcgggccgc acgcgtcccc agccgccccc cgcgcgcgcg
      181 tggccgagcc cagagaagcc ccggcgcggg gagcgccggc ccggcgcggg cgagggcgat
      241 gccgcggtga cggccccgcc atggcgaagc ccccggcggt ggcggcggcg gctgcagcgg
      301 cggcgtcgga ggagctgagc caggtcccgg acgaggaact gctgcgctgg agcaaggagg
      361 agctggcgcg gcggctgcgg cgcgccgagg gcgagaaggt gggcctcatg ctggagcacg
      421 gcggcctgat gcgcgacgtg aaccggcggc tgcagcagca cctgctggag atccgcggcc
      481 tcaaggacgt gaaccagcgg ctgcaggacg acaatcagga gctgcgtgag ctctgctgtt
      541 tcctggacga cgaccggcag aaagggcgca agctggcgcg cgagtggcag cgcttcggac
      601 gccacgcggc cggcgccgtg tggcacgagg tggcccgctc gcagcagaag ctacgggagc
      661 tcgaggcgcg ccaggaggcc ctgctgcgcg agaacctgga gctgaaagag ctggtgctgt
      721 tgctggacga ggagcgcgcg gcgctggcgg cggcgggggg cgctggcggc ggcggcggcg
      781 gcgcgggctc ccgcagctcc atcgacagcc aggccagcct gagcgggccc ctggcgggga
      841 gcgcagcggg ctcgggggcc cgcgacgttg gcgacggcag cagcacgtcc agtgcgggca
      901 gcggcggcag cccggaccac caccaccacg tcccagcggc tctgctgccc ccggggccgc
      961 acaaggttcc ggacggcaag gccggagcca cgcgccggtc tctggatgac ctgtcagcgc
     1021 cgccgcacca ccgaagcatc cctaacggcc tgcacgatcc ctcgtccact tacatcaggc
     1081 cattggagac caaggtgaag ctgttggacg gtgacaagct ccccccacag caggcaggct
     1141 ctggagaatt ccgtaccctt cggaaaggct tctccccata ccattcggaa tcccagctcg
     1201 catccctgcc gccctcctac caagaagtcc tacagaacgg cccagcctgc cccgtacccg
     1261 agctgccctc acccccgtcc accgtctaca gttcggcagg acagaaaccc gaggctgtcg
     1321 tgcacgccat gaaggttctg gaagtacatg agaaccttga ccggcaactt caagacagct
     1381 gtgaggagga cctgagcgag aaggagaagg ccatcgtgcg agagatgtgc aacgtggtct
     1441 ggaggaaact gggggacgcc gccagcacca agccctccat ccggcagcac ctgtctggta
     1501 atcagttcaa ggggccattg tagggccgct tctccgtgga cgtggactgg ccctgcctgg
     1561 agtctgaggc cttagacctg gcagaaactc cggcccagcc accgtctttc tccgtggtga
     1621 attgtacata ggacacggcc taccctggct gccctggtgt gatgctgaca gccaggcctc
     1681 cacctcctgc ctccctcacc agcaaacctt gggaagacga gaagccactg ctcgcttgcc
     1741 cgctcgctgc agccaagtgg ccaggcagcc tggctccccg tttgagctcc atgttctgtc
     1801 agcaagaagc ctctgagact ccaagccaag ggactgtctg ggaggtagcc tgctcttggt
     1861 agaaggtccc tcaacaagta ttctaactct ctgtccctta cactggacag atgccaccgg
     1921 agcctgaatc gtgacgcggg tggcactttt ctgctaccct gccagagcca ggaccctggg
     1981 tcacagagca ctgggtcccg tgtgtccatg actggctggg agctcagggt tccctgtcac
     2041 ctgggggtcg gtgctcagcc accccgaagc cagcttctcc tcgttagtat tcactccttc
     2101 agtgacgtct cctcaccaat gccaggctta gccactttgt aggtctctcc tgccaggctt
     2161 ccttttctgg tttacagcaa cataggaaag tcctggagag tgtctgagcc aggctcagca
     2221 ttctcaatgg gcaggtagaa ctgggccatt gcccagggtc actgtcaatg tgacggagca
     2281 cccccccccc cccccgcccg tgtgctacaa ggagccaccc ctgatcccct gatgaggttt
     2341 ccttgggaag gatgggggca tgcctggttc tggctttaat ctgctgtgtg gccttcagcc
     2401 agccactcag cttccctggg cccccagccg ttccttctgc ctcttgctca ctctagaaac
     2461 caccccagtt ttgtggacct ctgtcctcac agtggaagag ctcatgtggc aacctactgg
     2521 gaacatgcta ggccagcctg tttgtcatgc tgtctcctca caggtcacat ctgagcctta
     2581 gcccctccct ccaagggacc tgtgggcggg ggcggggggg gggcgggggg gtcaaatgcg
     2641 tgcttcagtg aacgttgctc gcgcctcagc cggaaggcgg cacatggctg tcaggagttt
     2701 tctctagtgt ggttggagga gagtgaggtg cttttgtgaa ccatgcagat gctgtctgta
     2761 ggaggccctg gccacactgc tggcttcgcc agttccgtgt atttacatcc acacccatca
     2821 gctgtcctca cgcaatggta cttagagccc catgcagcaa gcccaaagag cttgtccttg
     2881 cctcaggtcc ctcccaaacc ctgtgagcag aggggacagg ccaagaaggt gggtgacatc
     2941 cttgctcccc aacaagccca ggccccgtaa ccttgggtgg tacccagcac ctttgctgcc
     3001 cacacccttg ggtcccacac tctcagggga aaggcccatg gccctcggtg tgcccaggga
     3061 gtgttgcgca ggggctgtag gggaccggcc tactgctccg gctgttggtg gcactgggaa
     3121 gctctttcta ggagctgctg gatggtcaat cgatagaact tgcaactcca tctgccggcc
     3181 ccagctggta ctgggtattt ctaagtgggc tgctgggcag gcaagaccct tcctggttct
     3241 ttgaagccaa gaaaccgcag aataatgttg aggtatgtgg cccacacaag gtgggagcca
     3301 agtcagagag tcccagtcac atttgtatca ggacagttca gccacctctg aaataagcaa
     3361 taagtaagag ctcttggagt ctgaagacaa gaaagatcct gtccctagtg ctgcagggca
     3421 tccagggaat ctaaagagaa tttctcacag gctcctctgc ccttgtgcag gcagagagag
     3481 acaagctata ccccagccct cggcagtagg ctggcttccc taggacagcc tgggtcatat
     3541 ctcaaaccta acaggagagg ccagcagcaa cccagttgag cccggggcca gggagggcag
     3601 gtggtcttcc gtgacccttc ccttctggag ccttagcctt tgcagtgctg attctccacc
     3661 ccaagctcac aatatgcttg tgctggctcc acccccgtcc ccactgtgac aggtcacttg
     3721 gccccatcta gggtggcctg gccttccccg gagtcagaat ctgctgagca catcttcatt
     3781 tgcgatcaac agccacgcgc cagtgtttca agacaaagtg acctttcatt tttctttctt
     3841 gaaacttgag aggaagtgag atacatacta ctgatctttt tttttttttt tttttttttt
     3901 tttttaagaa acaaaatgca tggctgcaga gtggcagagg tgtctatttt catactgtgg
     3961 gggaaagcgt gctgcttttg ggaggggctg gagtgcctgg tttctgccct gggccggtct
     4021 tctataggag ttggtggtga gacctgcagc tgcccctcct gccctggccg tgtagagctg
     4081 gagcctgtgc acttcggccg tttctacctt ctatcgaacc actttgattt gtggagagag
     4141 aaaaaaaata gaacttttga tagtgtggta aaagcattga tttgaactat tttagtaaaa
     4201 ggagtaacat aagattgtga cagtgtctac tttgaactag ataataaagg cctctttgtg
     4261 agcctcgg
//
