LOCUS       NM_001404024            5648 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus coiled-coil domain containing 85A (Ccdc85a),
            transcript variant 4, mRNA.
ACCESSION   NM_001404024 XM_006514654
VERSION     NM_001404024.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5648)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5648)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929280.6 and BX255910.3.
            
            On Apr 7, 2022 this sequence version replaced XM_006514654.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR9219379.36715.1,
                                           SRR1660811.245272.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1001              AL929280.6         131194-132194
            1002-1956           AL929280.6         138131-139085
            1957-2033           BX255910.3         112619-112695       c
            2034-2168           BX255910.3         77914-78048         c
            2169-2288           BX255910.3         74584-74703         c
            2289-2387           BX255910.3         71392-71490         c
            2388-5648           BX255910.3         64226-67486         c
FEATURES             Location/Qualifiers
     source          1..5648
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 16.22 cM"
     gene            1..5648
                     /gene="Ccdc85a"
                     /note="coiled-coil domain containing 85A"
                     /db_xref="GeneID:216613"
                     /db_xref="MGI:MGI:2445069"
     exon            1..1001
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     CDS             741..2477
                     /gene="Ccdc85a"
                     /note="isoform 4 is encoded by transcript variant 4;
                     coiled-coil domain-containing protein 85A"
                     /codon_start=1
                     /product="coiled-coil domain-containing protein 85A
                     isoform 4"
                     /protein_id="NP_001390953.1"
                     /db_xref="GeneID:216613"
                     /db_xref="MGI:MGI:2445069"
                     /translation="MSKAAGGSAPAAESCPSAPAGASTPTGVDDLSKVTDEELLQWSK
                     EELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRD
                     LCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKELEVKQEEVVKENMEL
                     KELCMLLDEEKGVGCAGSRCSIDSQASLCQLVASATPYVRDVGDGSSTSSTGSTDSPD
                     HHKHHASGGSPEHLQKPRSEGSPEHTKHRSTSPEHLHKPRASGTPDHSKALKGPSPEH
                     HKPLCKGSPEQQRHPHPGSSPEVLPKHVLSGSPEHFQKHRPGGSPEHTRHSGGSPEHL
                     QKHALGGSLEHLPRARGTSPEHLKQHYGASPDHKHASGSGGSGGGSREGTLRRPAQED
                     SSSHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQATQNRSQPPTRNSSNMEKG
                     WGPRARRVLQWWQGCRGIGRCLPSLPGSFRLSSGADGNNSSLNSPASFSGHTTPSQQP
                     EPVVHSLKVLDVEETIDRQQGKEYGHDLSETEKAVVREMCNVVWRKLGDAAGSCPGIR
                     QHLSGNQYKGPM"
     exon            1002..1956
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2033
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     exon            2034..2168
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     exon            2169..2288
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     exon            2289..2387
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     exon            2388..5648
                     /gene="Ccdc85a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4165..4170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc85a"
                     /note="hexamer: AATAAA"
     polyA_site      4188
                     /gene="Ccdc85a"
                     /note="major polyA site"
     regulatory      4223..4228
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc85a"
                     /note="hexamer: AATAAA"
     polyA_site      4246
                     /gene="Ccdc85a"
     regulatory      5626..5631
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ccdc85a"
                     /note="hexamer: AATAAA"
     polyA_site      5648
                     /gene="Ccdc85a"
ORIGIN      
        1 aatcgtccct agcagcagag caccaggagc tcagggtccg gttgggcagc tgagtgccat
       61 tcgggtttgg cctttgcaga aggtgttgcg gaatgcgggc gccccgggag ccagcttcct
      121 ccctgctgct gctccccaat ccccgcccat ccttttctgg gctctgaaaa cccaaggctt
      181 cccagaacag tttaggatca gccataggac tacagctagc cagctgcgcg gagctttctg
      241 ggaaggacag cagctcgccc tagggtagca gcggagcctc ggggtttagc aagcgagagg
      301 gaagggcgtg tgcatcgtgt gcctgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt
      361 gtgtgtgtca gaccgtgagg gatggctgtc tggatctgag cgaaggagag ggcaggggat
      421 tgagacagat ctctcttggt gtccccgccc gctcctgctc cccggcgccc ttcaccatgg
      481 aattgcgccg agttgggacg gacctatgca gccaccagga actggctgtc gggccccgag
      541 attcggcagg tactcgcgct tggatggcga ggtaggatgg ccacgcagcg cgattcctgc
      601 cgtccccacg cagcggtccc ccggaggtac ctctgactct ggaagcgtac aggggtgtgg
      661 gaggaggcca cccagccgcg cctgcacctt cgccagtcgt ttcgcctcta cccactcgca
      721 cctgccgctg cgcggatacc atgtctaagg cggctggagg ctcagcgcca gcggcggaaa
      781 gttgtccctc ggctccggcc ggtgcgtcga cacccacggg cgtggatgat ctatctaaag
      841 tgacggacga agagctgctg cagtggagca aggaggagct gatccgcagc ctgcggcgag
      901 ccgaagccga gaaggtgagc gcgatgctgg accacagcaa cctcattcgc gaggtcaacc
      961 gccgcctgca gctgcatctc ggcgagatcc gagggctcaa ggatattaac cagaaactcc
     1021 aggaagacaa ccaggaactg agggacctat gctgtttcct ggatgatgac cggcagaaag
     1081 gcaaaagggt gtcccgggag tggcaaagat tgggtcgcta cacagctgga gtgatgcaca
     1141 aggaagtggc cttatacttg cagaagctga aggagctgga ggtgaagcag gaggaggtgg
     1201 tgaaggagaa catggaactt aaggaactct gcatgttgct ggacgaggag aagggcgtag
     1261 gatgtgccgg cagccgctgc tccatcgata gccaggccag cctgtgccag ctggttgcct
     1321 ccgctacccc ctatgtgcga gatgtgggtg atggcagcag cacctctagc actggcagta
     1381 ctgatagtcc tgaccaccac aaacaccatg ccagtggggg aagccctgaa catttacaga
     1441 agccccggag cgagggcagc ccagagcaca ccaaacacag gagcactagc cctgaacatc
     1501 tacacaaacc cagggcttct gggaccccag atcactccaa agcactgaaa ggacccagcc
     1561 ctgagcacca caagcccttg tgcaagggca gccccgagca gcagaggcac ccacatccag
     1621 ggagcagccc agaagtgctg cccaagcacg tgttgagtgg gagccctgaa catttccaga
     1681 agcataggcc aggaggcagc ccggaacaca ccaggcacag tggagggagc cctgagcatc
     1741 ttcagaaaca tgcccttggt gggagcctgg agcacctccc cagagccagg ggaacaagcc
     1801 cagagcatct caaacaacat tacggggcca gccctgatca caaacatgca agtggcagtg
     1861 gaggcagcgg cgggggcagc agggaaggca ccctccggcg gcctgctcaa gaggattcat
     1921 catcccatca ccggaatgtc tacagcggca tgaatgaatc aaccttgtcc tatgttaggc
     1981 agctggaggc cagagtcaga cagctggaag aagaaaatcg catgctgccc caggctaccc
     2041 agaatagaag tcaacctcca actagaaaca gctcaaatat ggagaaaggc tgggggccca
     2101 gagcccggcg ggtcttgcag tggtggcaag ggtgccgagg aataggacga tgcctgccat
     2161 ctctcccggg ttcttttagg ttgtcatcag gggctgatgg gaataacagt tcactcaact
     2221 ctccagctag cttcagtgga cataccacac cttctcagca gcctgaacct gtggtacatt
     2281 ctcttaaggt cttggatgtt gaggaaacta tagatcgtca gcagggtaaa gagtatggcc
     2341 atgaccttag tgagacagaa aaagctgtag tcagagaaat gtgcaatgtt gtgtggagga
     2401 aacttggaga tgctgcaggc tcctgtcctg gaattaggca acatttgtca ggaaaccagt
     2461 acaaagggcc tatgtgaaaa gcactgcctt caaacatgac atcatcacta ctagagacag
     2521 cagaaaaaga agacaaagaa gaaattcagt ttctacaaaa taaaactcat gacatcacat
     2581 ggagtgattg tacattgctc atatctccct tctaaatcct ttagtgtacc ttctcccata
     2641 cagctaatat gtgctataag tctcaacttt agtgttcata gcagtctcaa ggtagctttg
     2701 gaaaatcgtt ttagtattaa tgaaagtatt aatttcatga aagctgaaat gtttttgact
     2761 cttcacaacc atgattgaca tattgggtag tctgcatggt tggatgagtc cagtagagtc
     2821 cctgtggctt tgatagaggt ggttcattat atctaatggt aggagctttc tactgtgtgg
     2881 aagatatgaa aaagtatttt tgagcataca acctgggttg ggaagctccc tcatatatat
     2941 agcagttgag gaaagattgc ttcctgatgc aaatttagtt ggatgcaaga taacatttgg
     3001 ttttctcatt tgaattctga ggtgctaaaa aataacacaa aatattttac cagctagaaa
     3061 ggtaggagga atttttaaaa atgcttagca gagagtatca tttattttca tttggtcaag
     3121 ataaataatt taattttgat gagttgttta taaaggcatg tctttggacc atacaaccct
     3181 tcatatatat tcaacttacc aatgtcaact aacaaggaaa caaacataat taatttttct
     3241 aggagtttca agctgtgaca ttgtctgttt ctacaactta gtttttagac atgctgtata
     3301 cttaataaac tttatgtaaa ctttaaagtc ttgcactgcc ctaggaaaca gaagctttct
     3361 ttgcatatca ctgcagctat ctaatgtctt aggaggctaa cgcatgtcca ttattgaggc
     3421 taaatactct tttcagattg cttgagatgt gtgccagctt tgctagtttt ctgcctagtg
     3481 gtatagatgt ataatattag aatgtgtgta ctggaaatgc tatgatattt tgtgtttatc
     3541 taaatttaat gatcgtttct tgtatgaatg ttcaagaggc ctgtgacaga atgctgtttt
     3601 taccatagtt taagattata aagtagggat gcaacaattc ctggatagct tctaaactta
     3661 tgatttgatt cacagtcaat attctttgtt gtctataaat gaaatggttt tattatataa
     3721 tttattaatg aacattggca ggagaatgag aagaaatttg ccatagtaaa aatacctaat
     3781 tgctacttcc aaaaccgccc tctatcttct gaaaatattt atgggttcat ttaacataga
     3841 atcatctttc taattatcat tactgagtta taatttaaga ctcttccttt aaactgctat
     3901 agttttagtg tctaagagaa aattgttaca cacacacaca cacatacttt ctcacacaga
     3961 aacatccttc aattgttgta ttcctacagt ctgaagatat ttaaacaaat ttttgtgctt
     4021 gcagtagatc ctgcagtagc gatacaaagg acattggtct tttgacaaaa tacttgtgca
     4081 aattttgata ctgtatcaaa actatttttt taaagttcca cataaaattg agtattaagt
     4141 atatgtgttc atcttagcaa cagtaataaa ttatttaatc tcacagtatt tttgtctgtt
     4201 ttgaaatgtt cttccttaac agaataaatt tctaatagtc actgaatatc atcccttgtg
     4261 tgattatgat actagtagta atatagatca aaataaaaga catgcaaaag gcatattaaa
     4321 aatatgctta tgagggactt aatagtcaga gacatcttaa tttataccat tttctattat
     4381 agcctccagg agtatgattt aggaacagtt gaattttctt aataaaattc tcagttctta
     4441 aacttatact tggaatggaa atactaaaat agttttgaaa caatcagcat tattttatgt
     4501 atttgtggga aattttatag tagcacataa ggcttcttag aagttgctaa taagatggta
     4561 aaatgaggct tcctgtgctg agcattatac cagttttaag taatggcgta cattgatccc
     4621 atgagtaata ctgttttcct atgggatcat ttcaataaat ttactatcta atcattcctg
     4681 caacaaagcc taatttacat gtcttgacag tacttttagc tgccatgatg ctgatagact
     4741 gtcacaatct aacttttaat gaatgccttt ctcattttta gcacatgctt aaagctctgt
     4801 aggaatttgt cagctcatgt gacattccaa gagtttaatt ggtatgattt ccccttagtt
     4861 cagtgaatat ttagtgatgc ctaccactgc catacaattt tgggctagcc aaccatggtt
     4921 cttcgggatt ctcaagacat acaaggatga ataatatctc aggtcttggc agaagcttcc
     4981 tttatttttg acacctaaga taagattgtc tcagacatct gtttcacttg atctgaaaca
     5041 aactaccccc aatccttcca ttaattctca gactctatat gatgcagtca atttcctgct
     5101 gctacatctt ccctccatct aaaggcgaaa ctagcaaatc ttggcattta ttcctatgaa
     5161 agtaccttta agctagctta tcaaagtaga tcaccaacaa gatcaaaaca actatgagga
     5221 aatcacatgt tgatttctaa agaatcaaaa cttctccacc atatctaagg cagtacctta
     5281 ttctgaacaa taagtaactg atgcacatgg tctcctttgt ctacaaaaca gcaatttctt
     5341 atggctcatc ttcagatgag ggagatattt ttgcatggtt gggaggattg acaaatatag
     5401 tctcaattag agaagaatca tcatattggc caaatcacaa tgatatacta tcacattctg
     5461 cttttatata tcacccaact tacaagcctt acattttatg gtaactgcct tatattaaca
     5521 agagactctg ttttgattct tatatatgaa tattattatt ttaagctaaa aatctccact
     5581 actatttaat tctaaattgt agatgtctct aaaaatactt atgataataa atatcttatt
     5641 tcacaaaa
//
